JP2002516090A - 組換えナルボノライドポリケチドシンターゼ - Google Patents

組換えナルボノライドポリケチドシンターゼ

Info

Publication number
JP2002516090A
JP2002516090A JP2000550984A JP2000550984A JP2002516090A JP 2002516090 A JP2002516090 A JP 2002516090A JP 2000550984 A JP2000550984 A JP 2000550984A JP 2000550984 A JP2000550984 A JP 2000550984A JP 2002516090 A JP2002516090 A JP 2002516090A
Authority
JP
Japan
Prior art keywords
pks
gene
narvonolide
domain
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000550984A
Other languages
English (en)
Japanese (ja)
Inventor
ゲイリー アシュレイ，
メラニー シー． ベットラック，
メアリー ベットラック，
ロバート マクダニエル，
リ タン，
Original Assignee
コーサン バイオサイエンシーズ， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/141,908 external-priority patent/US6503741B1/en
Application filed by コーサン バイオサイエンシーズ， インコーポレイテッド filed Critical コーサン バイオサイエンシーズ， インコーポレイテッド
Publication of JP2002516090A publication Critical patent/JP2002516090A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
JP2000550984A 1998-05-28 1999-05-27 組換えナルボノライドポリケチドシンターゼ Withdrawn JP2002516090A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US8708098P 1998-05-28 1998-05-28
US09/141,908 US6503741B1 (en) 1998-05-28 1998-08-28 Polyketide synthase genes from Streptomyces venezuelae
US10088098P 1998-09-22 1998-09-22
US11913999P 1999-02-08 1999-02-08
US60/100,880 1999-02-08
US09/141,908 1999-02-08
US60/119,139 1999-02-08
US60/087,080 1999-02-08
PCT/US1999/011814 WO1999061599A2 (fr) 1998-05-28 1999-05-27 Synthase de polyketide narbonolide de recombinaison

Publications (1)

Publication Number Publication Date
JP2002516090A true JP2002516090A (ja) 2002-06-04

Family

ID=27492096

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000550984A Withdrawn JP2002516090A (ja) 1998-05-28 1999-05-27 組換えナルボノライドポリケチドシンターゼ

Country Status (6)

Country Link
EP (1) EP1082439A2 (fr)
JP (1) JP2002516090A (fr)
AU (1) AU762399C (fr)
CA (1) CA2328427A1 (fr)
NZ (1) NZ509006A (fr)
WO (1) WO1999061599A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
EP1754700A3 (fr) 1999-01-27 2007-05-09 Kosan Biosciences, Inc. synthese de polycetides
US6524841B1 (en) 1999-10-08 2003-02-25 Kosan Biosciences, Inc. Recombinant megalomicin biosynthetic genes and uses thereof
US7033818B2 (en) 1999-10-08 2006-04-25 Kosan Biosciences, Inc. Recombinant polyketide synthase genes
JP2005529579A (ja) 2000-05-02 2005-10-06 コーサン バイオサイエンシーズ， インコーポレイテッド ポリケチドの生合成のための過剰産生宿主
WO2002059322A2 (fr) * 2000-10-17 2002-08-01 Cubist Pharmaceuticlas, Inc. Compositions et methodes liees a la famille de genes biosynthetiques de la daptomycine
ES2337134T3 (es) 2002-03-12 2010-04-21 Bristol-Myers Squibb Company Derivados de c3-ciano-epotilona.
JP2014508516A (ja) 2011-01-28 2014-04-10 アミリス， インコーポレイテッド ゲルに封入されたマイクロコロニーのスクリーニング
MX2013013065A (es) 2011-05-13 2013-12-02 Amyris Inc Metodos y composiciones para detectar la produccion microbiana de compuestos inmiscibles em agua.
CN104540949B (zh) 2012-08-07 2018-05-29 阿迈瑞斯公司 用于稳定乙酰-辅酶a衍生化合物生成的方法
KR102159691B1 (ko) 2013-03-15 2020-09-24 아미리스 인코퍼레이티드 아세틸-코엔자임 a 유래 화합물을 생산하기 위한 포스포케톨라제 및 포스포트랜스아세틸라제의 용도
EP3663392A1 (fr) 2013-08-07 2020-06-10 Amyris, Inc. Procédés pour stabiliser la production de composés dérivés de l'acétyl-coenzyme a
BR112017027970A2 (pt) 2015-06-25 2018-08-28 Amyris, Inc. degrons dependentes de maltose, promotores responsivos à maltose, construtos de estabilização, e seu uso na produção de compostos não catabólicos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712146A (en) * 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
SK182498A3 (en) * 1996-07-05 2000-05-16 Biotica Tech Ltd Erythromycins and process for their preparation

Also Published As

Publication number Publication date
CA2328427A1 (fr) 1999-12-02
WO1999061599A3 (fr) 2000-01-27
WO1999061599A2 (fr) 1999-12-02
AU4213799A (en) 1999-12-13
AU762399B2 (en) 2003-06-26
AU762399C (en) 2004-02-05
NZ509006A (en) 2003-09-26
EP1082439A2 (fr) 2001-03-14

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Legal Events

Date Code Title Description
A300 Withdrawal of application because of no request for examination

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20060801