JP2002515500A5 - - Google Patents
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- Publication number
- JP2002515500A5 JP2002515500A5 JP2000549611A JP2000549611A JP2002515500A5 JP 2002515500 A5 JP2002515500 A5 JP 2002515500A5 JP 2000549611 A JP2000549611 A JP 2000549611A JP 2000549611 A JP2000549611 A JP 2000549611A JP 2002515500 A5 JP2002515500 A5 JP 2002515500A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- residue
- aryl
- heteroaryl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98109077.2 | 1998-05-19 | ||
| EP98109077A EP0960882A1 (en) | 1998-05-19 | 1998-05-19 | Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists |
| PCT/EP1999/003064 WO1999059992A1 (en) | 1998-05-19 | 1999-05-05 | Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002515500A JP2002515500A (ja) | 2002-05-28 |
| JP2002515500A5 true JP2002515500A5 (enExample) | 2006-04-20 |
| JP4503176B2 JP4503176B2 (ja) | 2010-07-14 |
Family
ID=8231959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000549611A Expired - Lifetime JP4503176B2 (ja) | 1998-05-19 | 1999-05-05 | 骨吸収防止剤及びビトロネクチン受容体拮抗薬としての新規のチエニル置換アシルグアニジン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6566366B1 (enExample) |
| EP (2) | EP0960882A1 (enExample) |
| JP (1) | JP4503176B2 (enExample) |
| AR (1) | AR018358A1 (enExample) |
| AT (1) | ATE322490T1 (enExample) |
| AU (1) | AU4138599A (enExample) |
| DE (1) | DE69930740T2 (enExample) |
| TW (2) | TW546294B (enExample) |
| WO (1) | WO1999059992A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7381642B2 (en) | 2004-09-23 | 2008-06-03 | Megica Corporation | Top layers of metal for integrated circuits |
| US6965165B2 (en) | 1998-12-21 | 2005-11-15 | Mou-Shiung Lin | Top layers of metal for high performance IC's |
| US7405149B1 (en) | 1998-12-21 | 2008-07-29 | Megica Corporation | Post passivation method for semiconductor chip or wafer |
| EP1187825A1 (en) * | 1999-06-07 | 2002-03-20 | Shire Biochem Inc. | Thiophene integrin inhibitors |
| EP1108721A1 (en) | 1999-12-15 | 2001-06-20 | Aventis Pharma Deutschland GmbH | Thienylalanine derivatives as inhibitors of cell adhesion |
| FR2806082B1 (fr) * | 2000-03-07 | 2002-05-17 | Adir | Nouveaux composes bicycliques antagonistes des recepteurs de la vitronectine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE10041428A1 (de) * | 2000-08-23 | 2002-03-07 | Merck Patent Gmbh | Biphenylderivate |
| DE10061876A1 (de) * | 2000-12-12 | 2002-06-20 | Aventis Pharma Gmbh | Arylierte Furan- und Thiophencarbonsäureamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| PL395097A1 (pl) * | 2001-06-11 | 2011-10-10 | Vertex Pharmaceuticals (Canada) Incorporated | Sposób wytwarzania związku o wzorze A stanowiącego pochodną tiofenu |
| US8329924B2 (en) * | 2001-06-11 | 2012-12-11 | Vertex Pharmaceuticals (Canada) Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
| ES2345438T3 (es) * | 2002-12-10 | 2010-09-23 | Virochem Pharma Inc. | Compuestos y metodos para el tratamiento o prevencion de infecciones por flavivirus. |
| US7098241B2 (en) * | 2002-12-16 | 2006-08-29 | Hoffmann-La Roche Inc. | Thiophene hydroxamic acid derivatives |
| US20050107350A1 (en) * | 2003-08-22 | 2005-05-19 | Pharmacia Corporation | Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith |
| GB0412553D0 (en) | 2004-06-04 | 2004-07-07 | Univ Aberdeen | Therapeutic agents for the treatment of bone conditions |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| EP2546246A3 (en) | 2005-05-13 | 2013-04-24 | Virochem Pharma Inc. | Compounds and methods for the treatment or prevention of flavivirus infections |
| EA201101492A1 (ru) | 2006-11-15 | 2012-09-28 | Вирокем Фарма Инк. | Аналоги тиофена для лечения или предупреждения флавивирусных инфекций |
| GB0705400D0 (en) | 2007-03-21 | 2007-05-02 | Univ Aberdeen | Therapeutic compounds andm their use |
| GB0817207D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | therapeutic apsac compounds and their use |
| GB0817208D0 (en) | 2008-09-19 | 2008-10-29 | Pimco 2664 Ltd | Therapeutic apsap compounds and their use |
| GB201311361D0 (en) | 2013-06-26 | 2013-08-14 | Pimco 2664 Ltd | Compounds and their therapeutic use |
| CN106458965A (zh) * | 2014-03-11 | 2017-02-22 | Ea制药株式会社 | 杂芳基羧酸酯衍生物的制造方法及其制造中间体 |
| JP6649902B2 (ja) | 2014-05-30 | 2020-02-19 | ファイザー・インク | 選択的アンドロゲン受容体モジュレーターとしてのカルボニトリル誘導体 |
| AU2015367528B2 (en) | 2014-12-17 | 2020-05-14 | Pimco 2664 Limited | N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and N-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5125050A (en) * | 1991-05-03 | 1992-06-23 | Bell Communications Research, Inc. | Vertical metallically loaded polarization splitter and polarization-diversified optical receiver |
| US5204350A (en) * | 1991-08-09 | 1993-04-20 | Merck & Co., Inc. | Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives |
| US5786373A (en) * | 1992-10-14 | 1998-07-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| ES2186720T3 (es) * | 1994-05-27 | 2003-05-16 | Merck & Co Inc | Composiciones para inhibir la reabsorcion osea mediada por osteoclastos. |
| FR2742752B1 (fr) * | 1995-12-21 | 1998-01-30 | Adir | Nouveaux composes du thiophene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| DE19629816A1 (de) * | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
-
1998
- 1998-05-19 EP EP98109077A patent/EP0960882A1/en not_active Withdrawn
-
1999
- 1999-05-05 EP EP99924879A patent/EP1086098B1/en not_active Expired - Lifetime
- 1999-05-05 AT AT99924879T patent/ATE322490T1/de not_active IP Right Cessation
- 1999-05-05 WO PCT/EP1999/003064 patent/WO1999059992A1/en not_active Ceased
- 1999-05-05 JP JP2000549611A patent/JP4503176B2/ja not_active Expired - Lifetime
- 1999-05-05 AU AU41385/99A patent/AU4138599A/en not_active Abandoned
- 1999-05-05 DE DE69930740T patent/DE69930740T2/de not_active Expired - Lifetime
- 1999-05-05 US US09/700,655 patent/US6566366B1/en not_active Expired - Lifetime
- 1999-05-17 AR ARP990102334A patent/AR018358A1/es unknown
- 1999-08-18 TW TW088108141A patent/TW546294B/zh not_active IP Right Cessation
- 1999-08-18 TW TW090121555A patent/TWI254710B/zh not_active IP Right Cessation
-
2002
- 2002-11-14 US US10/368,771 patent/US6660728B2/en not_active Expired - Lifetime