JP2002515439A - 脳腫瘍の治療のためのエーデルホシン - Google Patents

脳腫瘍の治療のためのエーデルホシン

Info

Publication number
JP2002515439A
JP2002515439A JP2000549264A JP2000549264A JP2002515439A JP 2002515439 A JP2002515439 A JP 2002515439A JP 2000549264 A JP2000549264 A JP 2000549264A JP 2000549264 A JP2000549264 A JP 2000549264A JP 2002515439 A JP2002515439 A JP 2002515439A
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JP
Japan
Prior art keywords
treatment
brain
tumors
tumor
patients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000549264A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002515439A5 (enExample
Inventor
ナーグラー アポロニア
Original Assignee
メドマルク ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メドマルク ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical メドマルク ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング
Publication of JP2002515439A publication Critical patent/JP2002515439A/ja
Publication of JP2002515439A5 publication Critical patent/JP2002515439A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2000549264A 1998-05-19 1999-05-11 脳腫瘍の治療のためのエーデルホシン Pending JP2002515439A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19822509A DE19822509A1 (de) 1998-05-19 1998-05-19 Edelfosin zur Behandlung von Hirntumoren
DE19822509.1 1998-05-19
PCT/EP1999/003241 WO1999059599A1 (de) 1998-05-19 1999-05-11 Edelfosin zur behandlung von hirntumoren

Publications (2)

Publication Number Publication Date
JP2002515439A true JP2002515439A (ja) 2002-05-28
JP2002515439A5 JP2002515439A5 (enExample) 2006-07-13

Family

ID=7868323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000549264A Pending JP2002515439A (ja) 1998-05-19 1999-05-11 脳腫瘍の治療のためのエーデルホシン

Country Status (6)

Country Link
US (1) US6514519B1 (enExample)
EP (1) EP1079838B1 (enExample)
JP (1) JP2002515439A (enExample)
AT (1) ATE223721T1 (enExample)
DE (2) DE19822509A1 (enExample)
WO (1) WO1999059599A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010509293A (ja) * 2006-11-10 2010-03-25 アルファプトーゼ ゲーエムベーハー トリ置換グリセロール化合物を含む経口投与剤形
JP2013227341A (ja) * 2006-11-10 2013-11-07 Radioprotect Alphaptose Ug (Haftungsbeschraenkt) & Co Kg 放射線傷害治療のための三置換グリセロール化合物の使用

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE226843T1 (de) * 1998-12-04 2002-11-15 Max Delbrueck Centrum Mittel zur tumortherapie auf liposomenbasis, die tamoxifen enthalten
US7041302B2 (en) * 2001-01-09 2006-05-09 Biother Corporation Therapeutic modulation of the tumor inflammatory response
JP2008539721A (ja) * 2005-05-02 2008-11-20 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク アルツハイマー病の治療のためのホスホイノシチドモジュレーション
DE102006019907A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung
JP5773569B2 (ja) * 2006-11-10 2015-09-02 アルファプトーゼ ゲーエムベーハーＡｌｐｈａｐｔｏｓｅ Ｇｎｂｈ 受容体リガンド模倣体を検出する方法
ES2391226T3 (es) * 2006-12-20 2012-11-22 Alphaptose Gmbh Forma farmacéutica tópica que comprende compuestos de glicerol tri-sustituido
RU2474427C2 (ru) 2006-12-20 2013-02-10 Универзитетсклиникум Хамбург-Эппендорф Применение тризамещенных соединений глицерина для лечения гематологических злокачественных опухолей
AU2008254328A1 (en) 2007-05-18 2008-11-27 The Johns Hopkins University A treatment simulator for brain diseases and method of use thereof
RU2382765C1 (ru) * 2008-10-24 2010-02-27 Государственное образовательное учреждение высшего профессионального образования "Московская государственная академия тонкой химической технологии имени М.В. Ломоносова" Rac-N,N-ДИМЕТИЛ-N-[2-(5-N',N'- ДИМЕТИЛАМИНОНАФТАЛЕН-1-СУЛЬФОНИЛОКСИ)ЭТИЛ]-N- {4-[(2-МЕТОКСИ-3-ОКТАДЕЦИЛОКСИ)ПРОП-1-ИЛОКСИКАРБОНИЛ]БУТИЛ} АММОНИЙИОДИД
WO2013156630A1 (en) 2012-04-20 2013-10-24 Alphaptose Gmbh S-enantiomer of a tri-substituted glycerol compound

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05502878A (ja) * 1990-01-03 1993-05-20 メドマルク　ファルマ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 静脈内適用可能なｅｔ１８―ｏｃｈ↓３の医薬調合物
JPH05504132A (ja) * 1989-12-12 1993-07-01 メドマルク　ファルマ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 活性化されたリンパ球の除去

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925669A (en) * 1994-03-22 1999-07-20 Molecular/Structural Bio Technologies, Inc. Carrier compositions for anti-neoplastic drugs
WO1997035588A1 (en) * 1996-03-27 1997-10-02 Uab Research Foundation Novel uses of phospholipase c inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05504132A (ja) * 1989-12-12 1993-07-01 メドマルク　ファルマ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 活性化されたリンパ球の除去
JPH05502878A (ja) * 1990-01-03 1993-05-20 メドマルク　ファルマ　ゲゼルシャフト　ミット　ベシュレンクテル　ハフツング 静脈内適用可能なｅｔ１８―ｏｃｈ↓３の医薬調合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6009057070, ＥＮＧＥＢＲＡＡＴＥＮ，Ｏ． ｅｔ ａｌ, "Ｅｆｆｅｃｔ ｏｆ ａｌｋｙｌ−ｌｙｓｏｐｈｏｓｐｈｏｌｉｐｉｄ ｏｎ ｇｌｉｏｂｌａｓｔｏｍａ ｃｅｌｌ ｉｎｖａｓｉｏｎ ｉｎｔｏ ｆｅｔａｌ ｒａｔ ｂｒａｉｎ ｔｉｓｓｕｅ ｉｎ ｖｉｔｒｏ", Ｃａｎｃｅｒ Ｒｅｓ, 1991, Ｖｏｌ．５１， Ｎｏ．６, ｐ．１７１３−９ *
JPN6009057071, ＢＥＲＤＥＬ，Ｗ．Ｅ． ｅｔ ａｌ, "Ｃｙｔｏｔｏｘｉｃｉｔｙ ｏｆ ａｌｋｙｌ−ｌｙｓｏｐｈｏｓｐｈｏｌｉｐｉｄ ｄｅｒｉｖａｔｉｖｅｓ ａｎｄ ｌｏｗ−ａｌｋｙｌ−ｃｌｅａｖａｇｅ ｅｎｚｙｍｅ ａｃｔｉｖｉｔｉｅｓ ｉｎ ｒａｔ ｂ", Ｃａｎｃｅｒ Ｒｅｓ, 1983, Ｖｏｌ．４３， Ｎｏ．２, ｐ．５４１−５ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010509293A (ja) * 2006-11-10 2010-03-25 アルファプトーゼ ゲーエムベーハー トリ置換グリセロール化合物を含む経口投与剤形
JP2013227341A (ja) * 2006-11-10 2013-11-07 Radioprotect Alphaptose Ug (Haftungsbeschraenkt) & Co Kg 放射線傷害治療のための三置換グリセロール化合物の使用

Also Published As

Publication number Publication date
DE19822509A1 (de) 1999-11-25
EP1079838B1 (de) 2002-09-11
US6514519B1 (en) 2003-02-04
EP1079838A1 (de) 2001-03-07
DE59902666D1 (de) 2002-10-17
WO1999059599A1 (de) 1999-11-25
ATE223721T1 (de) 2002-09-15

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