JP2002515060A5 - - Google Patents
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- JP2002515060A5 JP2002515060A5 JP1998543934A JP54393498A JP2002515060A5 JP 2002515060 A5 JP2002515060 A5 JP 2002515060A5 JP 1998543934 A JP1998543934 A JP 1998543934A JP 54393498 A JP54393498 A JP 54393498A JP 2002515060 A5 JP2002515060 A5 JP 2002515060A5
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- JP
- Japan
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Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4371397P | 1997-04-16 | 1997-04-16 | |
US60/043,713 | 1997-04-16 | ||
PCT/US1998/006035 WO1998046246A1 (en) | 1997-04-16 | 1998-03-25 | α-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2002515060A JP2002515060A (ja) | 2002-05-21 |
JP2002515060A5 true JP2002515060A5 (ja) | 2005-11-10 |
JP4308918B2 JP4308918B2 (ja) | 2009-08-05 |
Family
ID=21928513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP54393498A Expired - Lifetime JP4308918B2 (ja) | 1997-04-16 | 1998-03-25 | (2,6)−STエピトープクラスターを有するα−O−結合複合糖質、その製造方法および使用 |
Country Status (6)
Country | Link |
---|---|
US (2) | US6660714B1 (ja) |
EP (1) | EP0996455B1 (ja) |
JP (1) | JP4308918B2 (ja) |
AU (1) | AU750701C (ja) |
CA (1) | CA2286798C (ja) |
WO (1) | WO1998046246A1 (ja) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7550146B2 (en) * | 1997-04-16 | 2009-06-23 | Sloan-Kettering Institute For Cancer Research | Glycopeptide conjugates and uses thereof |
CA2286798C (en) | 1997-04-16 | 2014-01-07 | Sloan-Kettering Institute For Cancer Research | Alpha-o-linked glycoconjugates with clustered(2,6)-st epitopes, methods of preparation and uses thereof |
AU758097B2 (en) * | 1998-03-25 | 2003-03-13 | Sloan-Kettering Institute For Cancer Research | Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof |
US7824687B2 (en) | 1999-08-20 | 2010-11-02 | Sloan-Kettering Institute For Cancer Research | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof |
JP5111705B2 (ja) * | 1999-08-20 | 2013-01-09 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | 新規な複合多糖、グリコアミノ酸、これらへの中間体、及びこれらの使用 |
US7854934B2 (en) | 1999-08-20 | 2010-12-21 | Sloan-Kettering Institute For Cancer Research | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof |
JP2004534088A (ja) | 2001-07-06 | 2004-11-11 | スローン−ケッタリング・インスティテュート・フォア・キャンサー・リサーチ | 癌のための多価コンジュゲートワクチン |
US7504364B2 (en) * | 2002-03-01 | 2009-03-17 | Receptors Llc | Methods of making arrays and artificial receptors |
US20050238693A1 (en) * | 2002-05-20 | 2005-10-27 | Chemstop Pty Ltd. | Process for the preparation and activation of susbstances and a means of producing same |
US7469076B2 (en) * | 2003-09-03 | 2008-12-23 | Receptors Llc | Sensors employing combinatorial artificial receptors |
US20050136483A1 (en) * | 2003-09-03 | 2005-06-23 | Receptors Llc | Nanodevices employing combinatorial artificial receptors |
US20040137481A1 (en) * | 2002-09-16 | 2004-07-15 | Receptors Llc | Artificial receptor building blocks, components, and kits |
US20050037381A1 (en) * | 2002-09-16 | 2005-02-17 | Receptors Llc | Artificial receptors, building blocks, and methods |
US20060051802A1 (en) * | 2002-09-16 | 2006-03-09 | Receptors Llc | Artificial receptors, building blocks, and methods |
US20060057625A1 (en) * | 2002-09-16 | 2006-03-16 | Carlson Robert E | Scaffold-based artificial receptors and methods |
US20050037429A1 (en) * | 2003-03-28 | 2005-02-17 | Receptors Llc | Artificial receptors including reversibly immobilized building blocks and methods |
EP1613737A4 (en) * | 2003-03-28 | 2008-12-03 | Receptors Llc | ARTIFICIAL RECEPTORS COMPRISING REVERSIBLE IMMOBILIZED CONSTRUCTION BLOCKS AND METHODS |
US20060035267A1 (en) * | 2003-04-09 | 2006-02-16 | Livingston Philip O | Optimal polyvalent vaccine for cancer |
WO2005044841A1 (en) * | 2003-09-05 | 2005-05-19 | Sloan-Kettering Institute For Cancer Research | Method for preparing polyfunctionalized peptides and/or proteins via native chemical ligation |
US7884052B2 (en) * | 2004-09-03 | 2011-02-08 | Receptors Llc | Combinatorial artificial receptors including tether building blocks on scaffolds |
WO2006029383A2 (en) | 2004-09-11 | 2006-03-16 | Receptors Llc | Combinatorial artificial receptors including peptide building blocks |
JP4942014B2 (ja) * | 2004-09-14 | 2012-05-30 | 独立行政法人産業技術総合研究所 | O−結合型糖アミノ酸 |
ES2366552T3 (es) | 2006-01-13 | 2011-10-21 | Institut Pasteur | Síntesis enzimática a gran escala de glicoconjugados de mucina y sus aplicaciones en inmunología. |
EP2010556B1 (en) * | 2006-04-11 | 2015-09-23 | Sloan-Kettering Institute for Cancer Research | Homogeneous erythropoietin and method for their preparation |
CA2728344A1 (en) * | 2008-06-16 | 2010-01-14 | Academia Sinica | Compositions for inducing immune responses specific to globo h and ssea3 and uses thereof in cancer treatment |
ES2477549T3 (es) | 2008-06-16 | 2014-07-17 | Academia Sinica | Diagnóstico del cáncer según la concentración de anticuerpos contra Globo H y sus fragmentos |
WO2010006343A2 (en) * | 2008-07-11 | 2010-01-14 | Sloan-Kettering Institute For Cancer Research | Glycopeptide constructs and uses thereof |
CN105535955B (zh) * | 2009-06-16 | 2019-04-23 | 中央研究院 | Globo h及含新颖糖脂质佐剂的相关抗癌疫苗 |
NZ604089A (en) | 2010-06-11 | 2015-03-27 | Sloan Kettering Inst Cancer | Multivalent glycopeptide constructs and uses thereof |
EP2500033A1 (en) * | 2011-03-17 | 2012-09-19 | Institut Pasteur | Method for preparing muliple antigen glycopeptide carbohydrate conjugates |
US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
EP4170031A1 (en) | 2012-10-23 | 2023-04-26 | Caris Science, Inc. | Aptamers and uses thereof |
WO2014100434A1 (en) | 2012-12-19 | 2014-06-26 | Caris Science, Inc. | Compositions and methods for aptamer screening |
NZ729243A (en) * | 2014-08-22 | 2018-08-31 | Academia Sinica | Novel glycan conjugates and use thereof |
PT110526B (pt) | 2018-01-26 | 2021-02-04 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
CN111303112A (zh) * | 2020-02-28 | 2020-06-19 | 南京工业大学 | 一种固定二氧化碳的方法 |
Family Cites Families (29)
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US4971795A (en) | 1986-07-08 | 1990-11-20 | Biomira, Inc. | Enhancement of the cellular immune response using carbohydrate primed DTH effector cells expressing the CD5+/CD8- phenotype |
US5683674A (en) | 1987-01-07 | 1997-11-04 | Imperial Cancer Research Technology Ltd. | Antibody against human mucin core protein and method of preparing and using same |
US6054438A (en) | 1987-01-07 | 2000-04-25 | Imperial Cancer Research Technology Limited | Nucleic acid fragments encoding portions of the core protein of the human mammary epithelial mucin |
AU1103988A (en) | 1987-01-07 | 1988-07-27 | Imperial Cancer Research Technology Limited | Probe |
US5053489A (en) | 1988-01-29 | 1991-10-01 | Dana-Farber Cancer Institute, Inc. | Genetically engineered polypeptides with determinants of the human DF3 breast carcinoma-associated antigen |
US5229289A (en) | 1988-03-11 | 1993-07-20 | The Biomembrane Institute | Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates |
US5660834A (en) | 1988-03-11 | 1997-08-26 | The Biomembrane Institute | Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with carbohydrate-carrier conjugates |
EP0395217A3 (en) | 1989-04-28 | 1991-01-23 | The Biomembrane Institute | Bio-organic synthesis of dimeric lex (difucosyl y2; iii3fucv3-funcnlc6cer) and analogues thereof |
IL94872A (en) | 1989-06-30 | 1995-03-30 | Oncogen | Monoclonal or chimeric antibodies that react with human carcinoma, recombinant proteins that contain their anti-binding site, pharmaceutical preparations and kits that contain the |
US5212298A (en) | 1989-08-16 | 1993-05-18 | Monsanto Company | Method for producing synthetic N-linked glycoconjugates |
US5280113A (en) | 1989-08-16 | 1994-01-18 | Monsanto Company | Method for producing synthetic N-linked glycoconjugates |
IL105503A (en) * | 1992-04-28 | 1999-05-09 | Astra Ab | Carbon peptide couplets capable of eliciting an immune response of T cells |
US5376531A (en) | 1992-09-03 | 1994-12-27 | Northwestern University | Method of detecting cancer |
WO1995018781A1 (en) | 1994-01-06 | 1995-07-13 | Metabolix, Inc. | Methods for synthesizing oligomers containing hydroxy acid units |
US5708163A (en) * | 1994-03-15 | 1998-01-13 | Sloan-Kettering Institute Of Cancer Research | Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof |
US6303120B1 (en) | 1994-03-15 | 2001-10-16 | Memorial Sloan-Kettering Institute For Cancer Research | Synthesis of glycoconjugates of the lewis y epitope and uses thereof |
US5679769A (en) * | 1994-03-15 | 1997-10-21 | Sloan-Kettering Institute For Cancer Research | Synthesis of asparagine-linked glycopeptides on a polymeric solid support |
WO1995029927A2 (en) | 1994-05-02 | 1995-11-09 | Biomira, Inc. | Process for preparation of glycosides of tumor-associated carbohydrate antigens |
DE4436164A1 (de) | 1994-10-10 | 1996-04-11 | Hoechst Ag | Neue Kohlenhydratkonjugate als Inhibitoren der Zelladhäsion |
JP3139957B2 (ja) | 1995-03-17 | 2001-03-05 | 財団法人神奈川科学技術アカデミー | レクチンの固定化法及びそれを用いた細胞用基材 |
US5871990A (en) | 1996-05-15 | 1999-02-16 | Clausen; Henrik | UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase, gAlnAc-T3 |
EP0951484A4 (en) | 1997-01-13 | 2003-03-12 | Sloan Kettering Inst Cancer | KH-1 AND N3 ANTIGENS ASSOCIATED WITH COLON CANCER |
US7550146B2 (en) | 1997-04-16 | 2009-06-23 | Sloan-Kettering Institute For Cancer Research | Glycopeptide conjugates and uses thereof |
CA2286798C (en) * | 1997-04-16 | 2014-01-07 | Sloan-Kettering Institute For Cancer Research | Alpha-o-linked glycoconjugates with clustered(2,6)-st epitopes, methods of preparation and uses thereof |
CA2304599A1 (en) | 1997-09-25 | 1999-04-01 | Sloan-Kettering Institute For Cancer Research | Fucosyl gm1-klh conjugate vaccine against small cell lung cancer |
AU758097B2 (en) | 1998-03-25 | 2003-03-13 | Sloan-Kettering Institute For Cancer Research | Trimeric antigenic O-linked glycopeptide conjugates, methods of preparation and uses thereof |
JP5111705B2 (ja) | 1999-08-20 | 2013-01-09 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | 新規な複合多糖、グリコアミノ酸、これらへの中間体、及びこれらの使用 |
US7854934B2 (en) | 1999-08-20 | 2010-12-21 | Sloan-Kettering Institute For Cancer Research | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof |
US7824687B2 (en) | 1999-08-20 | 2010-11-02 | Sloan-Kettering Institute For Cancer Research | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof |
-
1998
- 1998-03-25 CA CA2286798A patent/CA2286798C/en not_active Expired - Lifetime
- 1998-03-25 US US09/083,776 patent/US6660714B1/en not_active Expired - Lifetime
- 1998-03-25 WO PCT/US1998/006035 patent/WO1998046246A1/en active IP Right Grant
- 1998-03-25 EP EP98913180A patent/EP0996455B1/en not_active Expired - Lifetime
- 1998-03-25 AU AU67792/98A patent/AU750701C/en not_active Expired
- 1998-03-25 JP JP54393498A patent/JP4308918B2/ja not_active Expired - Lifetime
-
2002
- 2002-07-25 US US10/205,021 patent/US7160856B2/en not_active Expired - Lifetime