JP2002514928A5 - - Google Patents

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Publication number
JP2002514928A5
JP2002514928A5 JP1999508771A JP50877199A JP2002514928A5 JP 2002514928 A5 JP2002514928 A5 JP 2002514928A5 JP 1999508771 A JP1999508771 A JP 1999508771A JP 50877199 A JP50877199 A JP 50877199A JP 2002514928 A5 JP2002514928 A5 JP 2002514928A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1999508771A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514928A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/013835 external-priority patent/WO1999001560A1/en
Publication of JP2002514928A publication Critical patent/JP2002514928A/ja
Publication of JP2002514928A5 publication Critical patent/JP2002514928A5/ja
Ceased legal-status Critical Current

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JP50877199A 1997-07-01 1998-07-01 脊椎動物テロメラーゼ遺伝子およびタンパク質ならびにその使用 Ceased JP2002514928A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US5141097P 1997-07-01 1997-07-01
US60/051,410 1997-07-01
US60/053,018 1997-07-19
US5332997P 1997-07-21 1997-07-21
US5301897P 1997-07-21 1997-07-21
US60/053,329 1997-07-21
US5464297P 1997-08-04 1997-08-04
US60/054,642 1997-08-04
US5828797P 1997-09-09 1997-09-09
US60/058,287 1997-09-09
PCT/US1998/013835 WO1999001560A1 (en) 1997-07-01 1998-07-01 Vertebrate telomerase genes and proteins and uses thereof

Publications (2)

Publication Number Publication Date
JP2002514928A JP2002514928A (ja) 2002-05-21
JP2002514928A5 true JP2002514928A5 (cg-RX-API-DMAC7.html) 2006-02-09

Family

ID=27535157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50877199A Ceased JP2002514928A (ja) 1997-07-01 1998-07-01 脊椎動物テロメラーゼ遺伝子およびタンパク質ならびにその使用

Country Status (9)

Country Link
US (3) US6916642B1 (cg-RX-API-DMAC7.html)
EP (1) EP0917579A1 (cg-RX-API-DMAC7.html)
JP (1) JP2002514928A (cg-RX-API-DMAC7.html)
KR (1) KR100581990B1 (cg-RX-API-DMAC7.html)
CN (1) CN1270634A (cg-RX-API-DMAC7.html)
AU (1) AU748442B2 (cg-RX-API-DMAC7.html)
CA (1) CA2294782A1 (cg-RX-API-DMAC7.html)
IL (1) IL133830A0 (cg-RX-API-DMAC7.html)
WO (1) WO1999001560A1 (cg-RX-API-DMAC7.html)

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US7585622B1 (en) * 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
US6777203B1 (en) 1997-11-19 2004-08-17 Geron Corporation Telomerase promoter driving expression of therapeutic gene sequences
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6093809A (en) 1996-10-01 2000-07-25 University Technology Corporation Telomerase
GB2321642B8 (en) * 1996-10-01 2006-08-22 Geron Corp Human telomerase reverse transcriptase promoter
US6610839B1 (en) 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US6808880B2 (en) 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US6475789B1 (en) 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
US7622549B2 (en) 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
CA2294782A1 (en) * 1997-07-01 1999-01-14 Cambia Biosystems Llc Vertebrate telomerase genes and proteins and uses thereof
US7378244B2 (en) 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
WO1999027113A1 (en) * 1997-11-26 1999-06-03 Geron Corporation Mouse telomerase reverse transcriptase
US6608188B1 (en) 1998-01-08 2003-08-19 Chugai Seiyaku Kabushiki Kaisha CRT-1 gene having reverse transcriptase motif
US7402307B2 (en) 1998-03-31 2008-07-22 Geron Corporation Method for identifying and killing cancer cells
US6337200B1 (en) 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
JP2002509716A (ja) 1998-03-31 2002-04-02 ユニバーシティ テクノロジー コーポレイション テロメラーゼ抗原に対する免疫応答を惹起するための方法および組成物
DE19916929A1 (de) 1999-04-15 2000-10-19 Bayer Ag Ein automatisierbarer Schnelltest zum Nachweis von Krebserkrankungen auf der Basis von Telomerase(hTC) mRNA mit spezifischen Primern und Sonden
US6912492B1 (en) 1999-05-25 2005-06-28 University Of Medicine & Dentistry Of New Jersey Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors
US6210950B1 (en) * 1999-05-25 2001-04-03 University Of Medicine And Dentistry Of New Jersey Methods for diagnosing, preventing, and treating developmental disorders due to a combination of genetic and environmental factors
US6664046B1 (en) 1999-12-16 2003-12-16 Roche Molecular Systems, Inc. Quantitation of hTERT mRNA expression
KR20010096991A (ko) * 2000-04-19 2001-11-08 임정빈 텔로머레이즈의 프로모터에 특정하게 결합하는더블유티이1 절편, 그 유전자, 발현벡터 및 그것을 이용한세포성장 억제 방법
AUPQ923400A0 (en) * 2000-08-07 2000-08-31 Children's Medical Research Institute Assays for alternative lengthening of telomeres
US7078491B1 (en) 2000-09-21 2006-07-18 Amgen Inc. Selective binding agents of telomerase
GB0031430D0 (en) * 2000-12-22 2001-02-07 Norsk Hydro As Polypeptides
GB0112342D0 (en) * 2001-05-21 2001-07-11 Norsk Hydro As Polypeptides
EP1440085B8 (de) * 2001-10-18 2010-08-04 Medicyte GmbH Transiente immortalisierung von zellen durch onkogenproteine oder telomerproteine
WO2004053116A2 (de) * 2002-12-06 2004-06-24 Technische Universität Dresden Gegen htert gerichtete polynucleotide und die verwendung dieser
EP1748067A1 (en) * 2005-07-29 2007-01-31 Institut Pasteur Polynucleotides encoding MHC class I-restricted hTERT epitopes, analogues thereof or polyepitopes
KR102511874B1 (ko) * 2006-07-28 2023-03-20 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 개선된 백신 및 이의 사용 방법
EP1994942A1 (en) * 2007-05-25 2008-11-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Pharmaceutical compositions comprising telomerase, and uses thereof
KR20130024888A (ko) 2010-02-16 2013-03-08 오슬로 유니버시티 하스피탈 에이치에프 폴리펩티드
RU2468030C2 (ru) 2010-04-09 2012-11-27 Государственное учебно-научное учреждение Химический факультет Московского государственного университета им. М.В. Ломоносова Ингибиторы теломеразы и способ их получения
JP6267190B2 (ja) 2012-05-11 2018-01-24 ジェムバックス アンド カエル カンパニー,リミティド 悪液質の予防用または治療用組成物
ES3046661T3 (en) 2012-05-11 2025-12-02 Gemvax & Kael Co Ltd Anti-inflammatory peptides and composition comprising the same
JP6272853B2 (ja) 2012-07-11 2018-01-31 ジェムバックス アンド カエル カンパニー,リミティド 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物
US20150125438A1 (en) * 2012-07-20 2015-05-07 Sang Jae Kim Anti-Inflammatory Peptides and Composition Comprising the Same
CN107312759B (zh) * 2012-09-19 2025-10-28 珍白斯凯尔有限公司 细胞穿透肽、包含该肽的缀合物、及包含该缀合物的组合物
EP2970990B1 (en) 2013-03-15 2018-07-18 Monsanto Technology LLC Compositions and methods for the production and delivery of rna
KR102258864B1 (ko) * 2013-04-19 2021-06-01 주식회사 젬백스앤카엘 허혈성 손상 치료 및 예방용 조성물
EP3004883B1 (en) 2013-06-07 2022-09-14 Gemvax & Kael Co., Ltd. Gv1001, gemcitabine and capecitabine for use in the treatment of pancreatic cancer in high eotaxin baseline level patients
JP6495899B2 (ja) 2013-06-21 2019-04-03 ジェムバックス アンド カエル カンパニー,リミティド ホルモン分泌調節剤、及びそれを含む組成物
KR102224965B1 (ko) * 2013-07-12 2021-03-09 주식회사 젬백스앤카엘 세포 투과성 펩티드 및 이를 포함하는 컨쥬게이트
AU2014337805B2 (en) 2013-10-23 2018-03-15 Gemvax & Kael Co., Ltd. Composition for treating and preventing benign prostatic hyperplasia
KR102494803B1 (ko) 2013-11-22 2023-02-06 주식회사 젬백스앤카엘 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물
EP3085380B1 (en) 2013-12-17 2020-06-17 Gemvax & Kael Co., Ltd. Composition for treating prostate cancer
ES2908096T3 (es) 2014-04-11 2022-04-27 Gemvax & Kael Co Ltd Péptido con actividad inhibidora de la fibrosis y composición que lo contiene
CN106659149B (zh) 2014-04-30 2020-05-19 珍白斯凯尔有限公司 用于器官、组织或细胞移植的组合物、试剂盒和移植方法
KR102413243B1 (ko) 2014-12-23 2022-06-27 주식회사 젬백스앤카엘 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물
JP6751097B2 (ja) 2015-02-27 2020-09-02 ジェムバックス アンド カエル カンパニー,リミティド 聴力損傷予防用ペプチド及びそれを含む組成物
US11015179B2 (en) 2015-07-02 2021-05-25 Gemvax & Kael Co., Ltd. Peptide having anti-viral effect and composition containing same
WO2017070237A1 (en) * 2015-10-19 2017-04-27 University Of Maryland, Baltimore Methods for generating engineered human primary blood dendritic cell lines
EP4272829A3 (en) 2016-04-07 2024-01-17 Gemvax & Kael Co., Ltd. Peptide having effects of increasing telomerase activity and extending telomere, and composition containing same
CN110117644A (zh) * 2019-04-18 2019-08-13 王金固 一种用于生物样本中rna的基因检测方法

Family Cites Families (15)

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US5645986A (en) 1992-05-13 1997-07-08 Board Of Reagents, The University Of Texas System Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5489508A (en) 1992-05-13 1996-02-06 University Of Texas System Board Of Regents Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5639613A (en) 1992-05-13 1997-06-17 Board Of Regents, University Of Texas System Methods for cancer diagnosis and prognosis
WO1995013382A1 (en) * 1993-11-12 1995-05-18 Geron Corporation Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
UA47407C2 (uk) * 1994-07-07 2002-07-15 Джерон Корпорейшн Рнк-компонент теломерази ссавця, олігонуклеотид (варіанти), рекомбінантна експресуюча плазміда (варіанти), еукаріотична клітина-хазяїн, трансформована за допомогою рекомбінантної експресуючої плазміди (варіанти), спосіб продукування рекомбінантного ферменту теломерази (варіанти), спосіб ідентифікації можливих агентів, що модулюють теломеразу, спосіб гальмування активності теломерази в клітинах людини (варіанти), спосіб визначення наявності неопластичного стану у пацієнта, спосіб визначення наявності рнк-компонента теломерази ссавця в клітині або клітинному зразку (варіанти)
US5972605A (en) 1994-07-07 1999-10-26 Geron Corporation Assays for regulators of mammalian telomerase expression
EP0799315A2 (en) * 1994-12-19 1997-10-08 Cold Spring Harbor Laboratory Telomerase protein component
US5770422A (en) 1996-07-08 1998-06-23 The Regents Of The University Of California Human telomerase
US6261836B1 (en) * 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
GB2321642B8 (en) * 1996-10-01 2006-08-22 Geron Corp Human telomerase reverse transcriptase promoter
US7390891B1 (en) * 1996-11-15 2008-06-24 Amgen Inc. Polynucleotides encoding a telomerase component TP2
US5919656A (en) 1996-11-15 1999-07-06 Amgen Canada Inc. Genes encoding telomerase protein 1
WO1998037181A2 (en) * 1997-02-20 1998-08-27 Whitehead Institute For Biomedical Research Telomerase catalytic subunit gene and encoded protein
CA2294782A1 (en) * 1997-07-01 1999-01-14 Cambia Biosystems Llc Vertebrate telomerase genes and proteins and uses thereof

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