JP2002501484A5 - - Google Patents

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Publication number
JP2002501484A5
JP2002501484A5 JP1998538801A JP53880198A JP2002501484A5 JP 2002501484 A5 JP2002501484 A5 JP 2002501484A5 JP 1998538801 A JP1998538801 A JP 1998538801A JP 53880198 A JP53880198 A JP 53880198A JP 2002501484 A5 JP2002501484 A5 JP 2002501484A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538801A
Other languages
English (en)
Japanese (ja)
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JP2002501484A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/004303 external-priority patent/WO1998039363A2/en
Publication of JP2002501484A publication Critical patent/JP2002501484A/ja
Publication of JP2002501484A5 publication Critical patent/JP2002501484A5/ja
Ceased legal-status Critical Current

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JP53880198A 1997-03-05 1998-03-05 免疫毒素および免疫寛容を誘導する方法 Ceased JP2002501484A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3998797P 1997-03-05 1997-03-05
US60/039,987 1997-03-05
PCT/US1998/004303 WO1998039363A2 (en) 1997-03-05 1998-03-05 Immunotoxins and methods of inducing immune tolerance

Publications (2)

Publication Number Publication Date
JP2002501484A JP2002501484A (ja) 2002-01-15
JP2002501484A5 true JP2002501484A5 (cg-RX-API-DMAC7.html) 2005-11-10

Family

ID=21908461

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53880198A Ceased JP2002501484A (ja) 1997-03-05 1998-03-05 免疫毒素および免疫寛容を誘導する方法

Country Status (8)

Country Link
US (2) US6632928B1 (cg-RX-API-DMAC7.html)
EP (1) EP1015496B1 (cg-RX-API-DMAC7.html)
JP (1) JP2002501484A (cg-RX-API-DMAC7.html)
AT (1) ATE433998T1 (cg-RX-API-DMAC7.html)
AU (1) AU733898B2 (cg-RX-API-DMAC7.html)
CA (1) CA2284079C (cg-RX-API-DMAC7.html)
DE (1) DE69840913D1 (cg-RX-API-DMAC7.html)
WO (1) WO1998039363A2 (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7288254B2 (en) 1995-10-30 2007-10-30 The United States Of America As Represented By The Secretary, Department Of Health And Human Services, Nih Use of immunotoxins to induce immune tolerance to pancreatic islet transplantation
US7696338B2 (en) 1995-10-30 2010-04-13 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin fusion proteins and means for expression thereof
US7517527B2 (en) 1995-10-30 2009-04-14 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in vivo T cell suppressant activity and methods of use
US7125553B1 (en) 1996-04-15 2006-10-24 The United States of America as represented by the Department of Health and Human Services c/o Centers for Disease Control and Prevention Methods of inducing immune tolerance using immunotoxins
EP1015496B1 (en) 1997-03-05 2009-06-17 THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Divalent anti-t cells immunotoxins and use thereof
AU768547B2 (en) * 1999-01-08 2003-12-18 Wisconsin Alumni Research Foundation Methods of prolonging transplant survival using immunotoxins and costimulation blockade of CD154 and CD28
US20020142000A1 (en) * 1999-01-15 2002-10-03 Digan Mary Ellen Anti-CD3 immunotoxins and therapeutic uses therefor
BR0009772A (pt) * 1999-04-14 2002-01-08 Us Health Composições contendo imunotoxinas e agentes que inibem a maturação de células dendrìticas para induzir tolerância imune a um enxerto
EP1189635A4 (en) * 1999-06-17 2003-04-23 Univ Vermont AUTOLOGOUS ADOPTIVE IMMUNOTHERAPY WITH T-CELLS OR B-CELLS B WHICH HAVE BEEN SENSITIZED TO ANTIGENS-SPECIFIC
US6492498B1 (en) 1999-11-15 2002-12-10 Regents Of The University Of Minnesota Multimeric immunotoxins
JP4927291B2 (ja) * 2000-05-18 2012-05-09 アメリカ合衆国 免疫毒素融合タンパク質及びその発現法
CA2455154A1 (en) * 2001-07-24 2003-02-13 Hans Konrad Mueller-Hermelink Receptor, the use thereof, and mouse antibodies
US20050069549A1 (en) 2002-01-14 2005-03-31 William Herman Targeted ligands
US7105347B2 (en) 2002-07-30 2006-09-12 Corning Incorporated Method and device for protein delivery into cells
US7691580B2 (en) * 2003-01-29 2010-04-06 Corning Incorporated Reverse protein delivery into cells on coded microparticles
US20090029460A1 (en) * 2004-01-26 2009-01-29 Peter Vollmers Neoplasm-specific polypeptides and their uses
WO2008020827A2 (en) * 2005-08-01 2008-02-21 Biogen Idec Ma Inc. Altered polypeptides, immunoconjugates thereof, and methods related thereto
US20090297540A1 (en) * 2005-10-21 2009-12-03 Andrew Mellor Induction of Indoleamine 2,3-Dioxygenase in Dendritic Cells by TLR Ligands and Uses thereof
EP2081602A2 (en) * 2006-10-25 2009-07-29 Amgen Inc. Toxin peptide therapeutic agents
US8420779B2 (en) 2007-05-22 2013-04-16 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
PT2197903E (pt) * 2007-09-04 2015-01-02 Us Gov Health & Human Serv Delecções no domínio ii da exotoxina a de pseudomonas que reduzem toxicidade não específica
AU2010285071A1 (en) * 2009-08-17 2012-02-02 Roche Glycart Ag Targeted immunoconjugates
EP2565667A1 (en) 2011-08-31 2013-03-06 Friedrich-Alexander-Universität Erlangen-Nürnberg Direction of arrival estimation using watermarked audio signals and microphone arrays
WO2025050404A1 (zh) * 2023-09-08 2025-03-13 成都维瑾柏鳌生物医药科技有限公司 一种药物组合物及其应用

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US4520226A (en) 1982-07-19 1985-05-28 The United States Of America As Represented By The Department Of Health And Human Services Treatment of graft versus host disease using a mixture of T-lymphocyte specific monoclonal antibody: ricin conjugates
EP0246307B1 (en) 1985-11-13 1994-02-02 University Hospital The Cys codon-modified dna
US4981979A (en) 1987-09-10 1991-01-01 Neorx Corporation Immunoconjugates joined by thioether bonds having reduced toxicity and improved selectivity
WO1989006968A1 (en) 1988-02-03 1989-08-10 Xoma Corporation Therapeutic use of anti-t cell immunotoxin for autoimmune diseases
IL89504A0 (en) 1988-03-08 1989-09-10 Univ Wyoming Diphtheria toxin derivative,process for the preparation thereof and pharmaceutical composition containing the same
US5980896A (en) * 1989-06-30 1999-11-09 Bristol-Myers Squibb Company Antibodies reactive with human carcinomas
EP0517751A4 (en) 1990-02-26 1993-03-31 Commonwealth Scientific & Industrial Research Organisation ( C.S.I.R.O. ) Shuttle plasmid for escherichia coli and mycobacteria
US5167956A (en) 1991-02-11 1992-12-01 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in-vivo t cell suppressant activity
US5725857A (en) 1991-02-11 1998-03-10 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in vivo T cell suppressant activity and methods of use
AU3583793A (en) 1992-01-24 1993-09-01 Tanox Biosystems, Inc. An immunotoxin including a cytotoxin with an unpaired cysteine residue in or near its receptor-binding site
PT616034E (pt) 1993-03-05 2005-02-28 Wyeth Corp Plasmideo para a producao de proteina crm e toxina da difteria
US5917017A (en) 1994-06-08 1999-06-29 President And Fellows Of Harvard College Diphtheria toxin vaccines bearing a mutated R domain
US5688781A (en) 1994-08-19 1997-11-18 Bristol-Myers Squibb Company Method for treating vascular leak syndrome
CA2218166C (en) 1995-04-14 2012-08-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of inducing immune tolerance using immunotoxins
US6103235A (en) 1995-10-30 2000-08-15 The United States Of America As Represented By The Department Of Health And Human Services Methods of inducing immune tolerance using immunotoxins
US5747474A (en) * 1996-07-29 1998-05-05 Immune Modulation, Inc. Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides
EP0968282A2 (en) 1997-03-05 2000-01-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Vectors and methods for expression of mutant proteins
EP1015496B1 (en) 1997-03-05 2009-06-17 THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Divalent anti-t cells immunotoxins and use thereof
US5801193A (en) * 1997-04-15 1998-09-01 Immune Modulation, Inc. Compositions and methods for immunosuppressing
DE69941182D1 (de) 1998-04-22 2009-09-10 Uab Research Foundation Verwendung von immunotoxinen zur auslösung einer immuntoleranz bei transplantation der inselzellen der bauchspeicheldrüse
AU768547B2 (en) 1999-01-08 2003-12-18 Wisconsin Alumni Research Foundation Methods of prolonging transplant survival using immunotoxins and costimulation blockade of CD154 and CD28
US20020142000A1 (en) 1999-01-15 2002-10-03 Digan Mary Ellen Anti-CD3 immunotoxins and therapeutic uses therefor
BR0009772A (pt) 1999-04-14 2002-01-08 Us Health Composições contendo imunotoxinas e agentes que inibem a maturação de células dendrìticas para induzir tolerância imune a um enxerto

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