JP2002514919A - 多価ライブラリーおよびポリクローナルライブラリー - Google Patents

多価ライブラリーおよびポリクローナルライブラリー

Info

Publication number
JP2002514919A
JP2002514919A JP54607598A JP54607598A JP2002514919A JP 2002514919 A JP2002514919 A JP 2002514919A JP 54607598 A JP54607598 A JP 54607598A JP 54607598 A JP54607598 A JP 54607598A JP 2002514919 A JP2002514919 A JP 2002514919A
Authority
JP
Japan
Prior art keywords
library
antibody
phage
polypeptide
members
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP54607598A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514919A5 (https=
Inventor
グレイ，ジェフ
ブークラー，ジョー
バルカーズ，ガナース
Original Assignee
バイオサイト ダイアグノスティックス，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/835,159 external-priority patent/US6555310B1/en
Priority claimed from US08/832,985 external-priority patent/US6057098A/en
Application filed by バイオサイト ダイアグノスティックス，インコーポレイテッド filed Critical バイオサイト ダイアグノスティックス，インコーポレイテッド
Publication of JP2002514919A publication Critical patent/JP2002514919A/ja
Publication of JP2002514919A5 publication Critical patent/JP2002514919A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP54607598A 1997-04-04 1998-04-03 多価ライブラリーおよびポリクローナルライブラリー Ceased JP2002514919A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/835,159 US6555310B1 (en) 1997-04-04 1997-04-04 Polyclonal libraries
US08/835,159 1997-04-04
US08/832,985 1997-04-04
US08/832,985 US6057098A (en) 1997-04-04 1997-04-04 Polyvalent display libraries
PCT/US1998/006704 WO1998047343A2 (en) 1997-04-04 1998-04-03 Antibodies or binding protein libraries displayed on phage, cells, or other replicatable genetic packages

Publications (2)

Publication Number Publication Date
JP2002514919A true JP2002514919A (ja) 2002-05-21
JP2002514919A5 JP2002514919A5 (https=) 2005-11-24

Family

ID=27125574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54607598A Ceased JP2002514919A (ja) 1997-04-04 1998-04-03 多価ライブラリーおよびポリクローナルライブラリー

Country Status (5)

Country Link
US (3) US6420113B1 (https=)
EP (1) EP0985033A4 (https=)
JP (1) JP2002514919A (https=)
AU (1) AU8755798A (https=)
WO (1) WO1998047343A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013511268A (ja) * 2009-11-18 2013-04-04 ピエール、ファーブル、メディカマン 新規なファージディスプレイベクター

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JP2013511268A (ja) * 2009-11-18 2013-04-04 ピエール、ファーブル、メディカマン 新規なファージディスプレイベクター

Also Published As

Publication number Publication date
US20030104477A1 (en) 2003-06-05
AU8755798A (en) 1998-11-13
WO1998047343A2 (en) 1998-10-29
EP0985033A2 (en) 2000-03-15
EP0985033A4 (en) 2005-07-13
WO1998047343A3 (en) 1998-12-10
WO1998047343A9 (en) 1999-04-15
US6420113B1 (en) 2002-07-16
US20050158796A1 (en) 2005-07-21

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