JP2002514053A5 - - Google Patents

Download PDF

Info

Publication number
JP2002514053A5
JP2002514053A5 JP1998514774A JP51477498A JP2002514053A5 JP 2002514053 A5 JP2002514053 A5 JP 2002514053A5 JP 1998514774 A JP1998514774 A JP 1998514774A JP 51477498 A JP51477498 A JP 51477498A JP 2002514053 A5 JP2002514053 A5 JP 2002514053A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1998514774A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514053A (ja
Filing date
Publication date
Priority claimed from US08/928,958 external-priority patent/US5877282A/en
Application filed filed Critical
Publication of JP2002514053A publication Critical patent/JP2002514053A/ja
Publication of JP2002514053A5 publication Critical patent/JP2002514053A5/ja
Withdrawn legal-status Critical Current

Links

JP51477498A 1996-09-20 1997-09-15 核局在化配列を持つ、核タンパク輸送のペプチド阻害物質およびその使用方法 Withdrawn JP2002514053A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2697896P 1996-09-20 1996-09-20
US60/026,978 1996-09-20
US08/928,958 1997-09-12
US08/928,958 US5877282A (en) 1996-09-20 1997-09-12 Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
PCT/US1997/016217 WO1998011907A1 (en) 1996-09-20 1997-09-15 Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2002514053A JP2002514053A (ja) 2002-05-14
JP2002514053A5 true JP2002514053A5 (https=) 2005-04-07

Family

ID=26701884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51477498A Withdrawn JP2002514053A (ja) 1996-09-20 1997-09-15 核局在化配列を持つ、核タンパク輸送のペプチド阻害物質およびその使用方法

Country Status (7)

Country Link
US (1) US5877282A (https=)
EP (1) EP1015012A4 (https=)
JP (1) JP2002514053A (https=)
AU (1) AU731725B2 (https=)
CA (1) CA2265571A1 (https=)
TW (1) TW575580B (https=)
WO (1) WO1998011907A1 (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495518B1 (en) 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
US7553929B2 (en) * 1994-06-13 2009-06-30 Vanderbilt University Cell permeable peptides for inhibition of inflammatory reactions and methods of use
FR2739621B1 (fr) * 1995-10-05 1997-12-05 Centre Nat Rech Scient Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives
US5962415A (en) * 1996-09-20 1999-10-05 Bristol-Myers Squibb Co. Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof
GB2337329B (en) * 1997-04-30 2001-09-05 Imp Cancer Res Tech Inhibitors of nuclear protein/nuclear receptor interaction
GB9708676D0 (en) * 1997-04-30 1997-06-18 Imp Cancer Res Tech Chemical compounds
AU766489B2 (en) * 1998-11-13 2003-10-16 Cyclacel Limited Transport vectors
AU5011200A (en) * 1999-05-14 2000-12-05 Arbor Vita Corporation Molecular interactions in hematopoietic cells
ATE385503T1 (de) 1999-06-28 2008-02-15 Inter K Pty Ltd Verfahren zur modulierung von integrin- vermittelter zellaktivitaet und hierfuer geeignete reagenzien
DE19933492B4 (de) * 1999-07-16 2008-01-10 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Konjugat zur Vermittlung eines zell-, kompartiment- oder membranspezifischen Transports von Wirksubstanzen, Verfahren zu dessen Herstellung und dessen Verwendung
US6312956B1 (en) * 1999-10-01 2001-11-06 Vanderbilt University Nuclear targeted peptide nucleic acid oligomer
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US6844324B1 (en) * 1999-11-12 2005-01-18 Massachusetts Institute Of Technology Modular peptide mediated intracellular delivery system and uses therefore
EP1235914A2 (en) * 1999-11-24 2002-09-04 Joseph Rosenecker Polypeptides comprising multimers of nuclear localization signals or of protein transduction domains and their use for transferring molecules into cells
EP1862471A3 (en) * 2000-02-07 2008-05-28 Wisconsin Alumni Research Foundation Pharmacologically active antiviral peptides and methods of their use
JP4896333B2 (ja) * 2000-02-07 2012-03-14 ウイスコンシン アラムニ リサーチ ファンデーション 薬理活性抗ウイルスペプチドおよびそれらの使用法
GB0103110D0 (en) 2000-08-25 2001-03-28 Aventis Pharma Inc A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1
US20040086896A1 (en) * 2001-04-19 2004-05-06 Julie Carman Polynucleotides and polypeptides associated with the NF-kB pathway
AU2002252705A1 (en) * 2001-04-19 2002-11-05 Bristol-Myers Squibb Company Polynucleotides and polypeptides associated with the nf-kb pathway
ATE489462T1 (de) * 2002-04-25 2010-12-15 Toagosei Co Ltd Antimikrobielles polypeptid und nutzung davon
EP2418219B1 (en) * 2003-10-17 2018-06-27 InterK Peptide Therapeutics Limited Methods and agents for the treatment of cancer
US7674771B2 (en) * 2003-10-29 2010-03-09 Toagosei Co., Ltd Antimicrobial peptides and utilization of the same
WO2005060541A2 (en) * 2003-12-01 2005-07-07 Wisconsin Alumni Research Foundation Peptides and methods for inducing cellular resistance to infection
US20050203150A1 (en) * 2004-03-09 2005-09-15 Haffar Omar K. Compounds, compositions and methods for inhibiting or treating HIV-1
JP4507080B2 (ja) * 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
WO2006056227A1 (en) * 2004-11-27 2006-06-01 Eberhard-Karls- Universität Tübingen Universitätsklinikum Conjugates comprising the active agent and flanking or branched-chain peptides
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
US20090030179A1 (en) * 2005-02-15 2009-01-29 Toagosei Co., Ltd Antimicrobial peptide and use thereof
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20110105408A1 (en) * 2008-02-22 2011-05-05 Inter-K Pty Limited Therapeutic peptides
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
JP2012533521A (ja) 2008-07-17 2012-12-27 ニュートリペップ・ピーティーワイ・リミテッド 治療剤
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
WO2012048721A1 (en) 2010-10-14 2012-04-19 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
KR20160023669A (ko) 2013-06-26 2016-03-03 자이겐 인플라메이션 리미티드 다양한 질병의 치료를 위한 jnk 신호 전달 경로의 세포 투과성 펩타이드 억제자의 새로운 용도
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
HUE049292T2 (hu) 2013-08-07 2020-09-28 Yeda Res & Dev A P53 mutánsok újraaktíválására képes peptidek
KR20150050646A (ko) * 2013-10-29 2015-05-11 삼성전자주식회사 융합 펩타이드 및 이의 세포막투과를 위한 용도
CN108884137B (zh) * 2016-02-04 2022-04-05 耶达研究及发展有限公司 肽及其在治疗与突变型p53相关的疾病、病症或病况中的用途
BR112022011744A2 (pt) * 2020-02-18 2022-09-20 Cellivery Therapeutics Inc Peptídeo sintético inibidor de importação nuclear permeável à célula melhorado para inibição de tempestade de citocina ou doença inflamatória e uso do mesmo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135736A (en) * 1988-08-15 1992-08-04 Neorx Corporation Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
IL106760A (en) * 1992-08-25 1999-12-31 Miles Inc Protein-nucleic acid hybrid construct for translocating an exogenous nucleic acid into a target cell and nucleus
JPH09510352A (ja) * 1994-03-15 1997-10-21 プリズム ファーマシューティカルズ,インコーポレイティド 遺伝子療法及び前部の眼疾患のためのヘパリン結合成長因子
WO1995031999A1 (en) * 1994-05-23 1995-11-30 Immunogiology Research Institute, Inc. Compositions of transactivating proteins of human immunodeficiency virus
US5807746A (en) * 1994-06-13 1998-09-15 Vanderbilt University Method for importing biologically active molecules into cells

Similar Documents

Publication Publication Date Title
JP2000502280A5 (https=)
JP2000501771A5 (https=)
JP2000515319A5 (https=)
JP2000501599A5 (https=)
JP2000501018A5 (https=)
JP2000500076A5 (https=)
JP2000501324A5 (https=)
JP2000500026A5 (https=)
JP2000513978A5 (https=)
JP2000502472A5 (https=)
JP2000501338A5 (https=)
JP2000501825A5 (https=)
JP2000511597A5 (https=)
JP2000500874A5 (https=)
JP2000502485A5 (https=)
JP2000502425A5 (https=)
JP2000501774A5 (https=)
JP2000500912A5 (https=)
JP2000502570A5 (https=)
JP2000501876A5 (https=)
JP2000501744A5 (https=)
JP2000501229A5 (https=)
JP2000502316A5 (https=)
JP2000500857A5 (https=)
JP2000502714A5 (https=)