JP2002510653A5 - - Google Patents
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- Publication number
- JP2002510653A5 JP2002510653A5 JP2000542042A JP2000542042A JP2002510653A5 JP 2002510653 A5 JP2002510653 A5 JP 2002510653A5 JP 2000542042 A JP2000542042 A JP 2000542042A JP 2000542042 A JP2000542042 A JP 2000542042A JP 2002510653 A5 JP2002510653 A5 JP 2002510653A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition
- disease
- effective amount
- condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 28
- 239000000203 mixture Substances 0.000 description 16
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000001384 succinic acid Substances 0.000 description 3
- 239000013543 active substance Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 101000599951 Homo sapiens Insulin-like growth factor I Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 102100037852 Insulin-like growth factor I Human genes 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- -1 succinic acid compound Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8000898P | 1998-04-03 | 1998-04-03 | |
| US60/080,008 | 1998-04-03 | ||
| PCT/US1999/007531 WO1999051272A1 (en) | 1998-04-03 | 1999-04-02 | Injectable igf-formulations containing succinate as buffering agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002510653A JP2002510653A (ja) | 2002-04-09 |
| JP2002510653A5 true JP2002510653A5 (https=) | 2006-05-25 |
Family
ID=22154445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000542042A Pending JP2002510653A (ja) | 1998-04-03 | 1999-04-02 | 緩衝剤としてコハク酸を含有する注射可能なｉｇｆ処方物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20070249522A1 (https=) |
| EP (1) | EP1069912B1 (https=) |
| JP (1) | JP2002510653A (https=) |
| AT (1) | ATE367828T1 (https=) |
| AU (1) | AU3473999A (https=) |
| DE (1) | DE69936638T2 (https=) |
| DK (1) | DK1069912T3 (https=) |
| ES (1) | ES2288018T3 (https=) |
| PT (1) | PT1069912E (https=) |
| WO (1) | WO1999051272A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60031999T2 (de) | 1999-10-04 | 2007-06-06 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Stabilisierte flüssige polypeptid-haltige pharmazeutische zusammensetzungen |
| US6887462B2 (en) | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
| AU2002325712C1 (en) | 2001-08-30 | 2008-07-31 | Stem Cell Therapeutics Inc. | Differentiation of neural stem cells and therapeutic use theeof |
| JP4906231B2 (ja) | 2001-09-14 | 2012-03-28 | ステム セル セラピューティクス インコーポレイテッド | プロラクチン誘導性の神経幹細胞数の増加ならびにその治療用途 |
| WO2003024471A2 (en) * | 2001-09-18 | 2003-03-27 | Stem Cell Therapeutics Inc. | Effect of growth hormone and igf-1 on neural stem cells and therapeutic application |
| WO2004011497A1 (en) | 2002-07-31 | 2004-02-05 | Stem Cell Therapeutics Inc. | Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap) |
| DE602004019761D1 (de) | 2003-01-08 | 2009-04-16 | Novartis Vaccines & Diagnostic | Stabilisierte wässrige zusammensetzungen mit gewebefaktorinhibitor (tfpi) oder gewebefaktorinhibitor-variante |
| US7534765B2 (en) | 2005-09-27 | 2009-05-19 | Stem Cell Therapeutics Corp. | Pregnancy-induced oligodendrocyte precursor cell proliferation regulated by prolactin |
| TWI705820B (zh) * | 2018-06-22 | 2020-10-01 | 美商美國禮來大藥廠 | Gip/glp1促效劑組合物 |
| CN121489917A (zh) * | 2019-05-15 | 2026-02-10 | 贝克森生物医药公司 | 用于皮下注射的氯胺酮制剂 |
| US11097023B1 (en) * | 2020-07-02 | 2021-08-24 | Par Pharmaceutical, Inc. | Pre-filled syringe containing sugammadex |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0080879B1 (en) * | 1981-11-28 | 1986-10-01 | Sunstar Kabushiki Kaisha | Pharmaceutical composition containing interferon in stable state |
| JPS6069037A (ja) * | 1983-09-26 | 1985-04-19 | Sunstar Inc | エリテマト−デス治療用外用剤 |
| US4605555A (en) * | 1984-09-20 | 1986-08-12 | Sun Star Kabushiki Kaisha | Composition and method for treating keratosic disorder of skin and mucosa |
| EP0284249A1 (en) * | 1987-03-13 | 1988-09-28 | Interferon Sciences, Inc. | Lyophilized lymphokine composition |
| US5151265A (en) * | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
| ATE90570T1 (de) * | 1988-01-29 | 1993-07-15 | Sumitomo Pharma | Verbesserte formulierungen mit kontrollierter abgabe. |
| US5374620A (en) * | 1990-06-07 | 1994-12-20 | Genentech, Inc. | Growth-promoting composition and its use |
| US5126324A (en) * | 1990-06-07 | 1992-06-30 | Genentech, Inc. | Method of enhancing growth in patients using combination therapy |
| US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
| DE69426292T2 (de) * | 1993-02-23 | 2001-05-17 | Genentech, Inc. | Stabilisierung von mit organischen lösungsmittel behandelten polypeptiden mit einem hilfsstoff |
| IT1272252B (it) * | 1994-05-16 | 1997-06-16 | Applied Research Systems | Formulazioni liquide di interferone beta |
| TW426523B (en) * | 1995-04-06 | 2001-03-21 | Hoffmann La Roche | Interferon solution |
| US6511811B1 (en) * | 1995-06-07 | 2003-01-28 | The Regents Of The University Of California | Protein kinase C antagonist related to insulin receptor |
| US5977057A (en) * | 1996-05-08 | 1999-11-02 | The University Of Vermont And State Agricultural College | Thrombosis prophylaxis for factor VLEIDEN carriers |
| US5783556A (en) * | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
| DE19825736C2 (de) * | 1997-06-11 | 2003-09-18 | Hyundai Electronics Ind | Verfahren zum Bilden eines Kondensators einer Halbleitervorrichtung |
| US6663899B2 (en) * | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
| US6887462B2 (en) * | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
-
1999
- 1999-04-02 AT AT99916414T patent/ATE367828T1/de not_active IP Right Cessation
- 1999-04-02 ES ES99916414T patent/ES2288018T3/es not_active Expired - Lifetime
- 1999-04-02 EP EP99916414A patent/EP1069912B1/en not_active Expired - Lifetime
- 1999-04-02 AU AU34739/99A patent/AU3473999A/en not_active Abandoned
- 1999-04-02 DK DK99916414T patent/DK1069912T3/da active
- 1999-04-02 PT PT99916414T patent/PT1069912E/pt unknown
- 1999-04-02 JP JP2000542042A patent/JP2002510653A/ja active Pending
- 1999-04-02 WO PCT/US1999/007531 patent/WO1999051272A1/en not_active Ceased
- 1999-04-02 DE DE69936638T patent/DE69936638T2/de not_active Expired - Fee Related
-
2007
- 2007-07-03 US US11/773,184 patent/US20070249522A1/en not_active Abandoned
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