JP2002507434A - 検出複合体に関する方法、キットおよび組成物 - Google Patents
検出複合体に関する方法、キットおよび組成物Info
- Publication number
- JP2002507434A JP2002507434A JP2000538214A JP2000538214A JP2002507434A JP 2002507434 A JP2002507434 A JP 2002507434A JP 2000538214 A JP2000538214 A JP 2000538214A JP 2000538214 A JP2000538214 A JP 2000538214A JP 2002507434 A JP2002507434 A JP 2002507434A
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- complex
- component
- residue
- pna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 230000000717 retained effect Effects 0.000 description 1
- 238000004366 reverse phase liquid chromatography Methods 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 229910052707 ruthenium Inorganic materials 0.000 description 1
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
- 230000009291 secondary effect Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 208000007056 sickle cell anemia Diseases 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- KUYMVWXKHQSIAS-UHFFFAOYSA-N tert-butyl 2-chloroacetate Chemical compound CC(C)(C)OC(=O)CCl KUYMVWXKHQSIAS-UHFFFAOYSA-N 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 description 1
- 238000006276 transfer reaction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical class [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 238000007738 vacuum evaporation Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7921198P | 1998-03-24 | 1998-03-24 | |
| US60/079,211 | 1998-03-24 | ||
| PCT/US1999/006422 WO1999049293A2 (en) | 1998-03-24 | 1999-03-24 | Methods, kits and compositions pertaining to detection complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002507434A true JP2002507434A (ja) | 2002-03-12 |
| JP2002507434A5 JP2002507434A5 (enExample) | 2005-12-22 |
Family
ID=22149128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000538214A Abandoned JP2002507434A (ja) | 1998-03-24 | 1999-03-24 | 検出複合体に関する方法、キットおよび組成物 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1064399A2 (enExample) |
| JP (1) | JP2002507434A (enExample) |
| KR (1) | KR20010042167A (enExample) |
| AU (1) | AU3012599A (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007512837A (ja) * | 2003-12-03 | 2007-05-24 | アボット・ラボラトリーズ | 二本鎖直鎖核酸プローブ及びその使用 |
| WO2008096562A1 (ja) * | 2007-02-06 | 2008-08-14 | Konica Minolta Medical & Graphic, Inc. | マイクロチップ検査システム、マイクロチップ、マイクロチップ検査装置及びプログラム |
| JP2011201943A (ja) * | 2010-03-24 | 2011-10-13 | Saitama Univ | Ｆｒｅｔを利用した酵素活性測定基質及びその製造方法 |
| JP2015097532A (ja) * | 2004-02-18 | 2015-05-28 | クロモセル コーポレイション | シグナリングプローブを使用する方法および材料 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3014093T3 (en) | 2014-07-30 | 2025-04-16 | Harvard College | Method for determining nucleic acids |
| EP4339956A3 (en) * | 2016-11-08 | 2024-06-19 | President and Fellows of Harvard College | Multiplexed imaging using merfish, expansion microscopy, and related technologies |
| US11788123B2 (en) | 2017-05-26 | 2023-10-17 | President And Fellows Of Harvard College | Systems and methods for high-throughput image-based screening |
| CN113366116A (zh) | 2018-12-13 | 2021-09-07 | 哈佛学院院长及董事 | 用于merfish和其他应用的扩增方法和系统 |
-
1999
- 1999-03-24 EP EP99911496A patent/EP1064399A2/en not_active Withdrawn
- 1999-03-24 AU AU30125/99A patent/AU3012599A/en not_active Abandoned
- 1999-03-24 KR KR1020007010618A patent/KR20010042167A/ko not_active Ceased
- 1999-03-24 JP JP2000538214A patent/JP2002507434A/ja not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007512837A (ja) * | 2003-12-03 | 2007-05-24 | アボット・ラボラトリーズ | 二本鎖直鎖核酸プローブ及びその使用 |
| JP2015097532A (ja) * | 2004-02-18 | 2015-05-28 | クロモセル コーポレイション | シグナリングプローブを使用する方法および材料 |
| WO2008096562A1 (ja) * | 2007-02-06 | 2008-08-14 | Konica Minolta Medical & Graphic, Inc. | マイクロチップ検査システム、マイクロチップ、マイクロチップ検査装置及びプログラム |
| JP2011201943A (ja) * | 2010-03-24 | 2011-10-13 | Saitama Univ | Ｆｒｅｔを利用した酵素活性測定基質及びその製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1064399A2 (en) | 2001-01-03 |
| AU3012599A (en) | 1999-10-18 |
| KR20010042167A (ko) | 2001-05-25 |
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