JP2002506204A - 可逆的アフィニティー電気泳動を用いる精製および検出プロセス - Google Patents

可逆的アフィニティー電気泳動を用いる精製および検出プロセス

Info

Publication number
JP2002506204A
JP2002506204A JP2000534862A JP2000534862A JP2002506204A JP 2002506204 A JP2002506204 A JP 2002506204A JP 2000534862 A JP2000534862 A JP 2000534862A JP 2000534862 A JP2000534862 A JP 2000534862A JP 2002506204 A JP2002506204 A JP 2002506204A
Authority
JP
Japan
Prior art keywords
analyte
electrophoretic medium
electric field
affinity ligand
changed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000534862A
Other languages
English (en)
Japanese (ja)
Inventor
アブラムス，エズラ，エス．
ハモンド，フィリップ，ダブリュ．
ミュア，アンドリュー，アール．
ボールズ，ティー．，クリスチャン
Original Assignee
モザイク テクノロジーズ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by モザイク テクノロジーズ filed Critical モザイク テクノロジーズ
Publication of JP2002506204A publication Critical patent/JP2002506204A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2000534862A 1998-03-03 1999-03-03 可逆的アフィニティー電気泳動を用いる精製および検出プロセス Pending JP2002506204A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7661498P 1998-03-03 1998-03-03
US60/076,614 1998-03-03
PCT/US1999/004849 WO1999045374A2 (fr) 1998-03-03 1999-03-03 Procedes de purification et de detection par electrophorese d'affinite reversible

Publications (1)

Publication Number Publication Date
JP2002506204A true JP2002506204A (ja) 2002-02-26

Family

ID=22133151

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000534862A Pending JP2002506204A (ja) 1998-03-03 1999-03-03 可逆的アフィニティー電気泳動を用いる精製および検出プロセス

Country Status (5)

Country Link
EP (1) EP1068518A2 (fr)
JP (1) JP2002506204A (fr)
AU (1) AU2896399A (fr)
CA (1) CA2322975A1 (fr)
WO (1) WO1999045374A2 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002350400A (ja) * 2001-05-29 2002-12-04 Aloka Co Ltd 電気泳動装置
JP2007512509A (ja) * 2003-11-05 2007-05-17 エグザクト サイエンシーズ コーポレイション 反復的親和性分離およびその使用
JP2009516176A (ja) * 2005-11-10 2009-04-16 テラダイン、 インコーポレイテッド ローカルに順序付けられたストロービング
JP2010508496A (ja) * 2006-08-29 2010-03-18 ベクトン・ディキンソン・アンド・カンパニー 無担体の偏向電気泳動の方法及び装置
JP2010536790A (ja) * 2007-08-17 2010-12-02 パーデュー・リサーチ・ファウンデーション Ｐｓｍａ結合性リガンド−リンカー結合体及び使用方法
US9636413B2 (en) 2012-11-15 2017-05-02 Endocyte, Inc. Conjugates for treating diseases caused by PSMA expressing cells
US9951324B2 (en) 2010-02-25 2018-04-24 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10188759B2 (en) 2015-01-07 2019-01-29 Endocyte, Inc. Conjugates for imaging
US10398791B2 (en) 2013-10-18 2019-09-03 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0981647B1 (fr) 1997-05-16 2006-08-09 EXACT Sciences Corporation Analyse electrophoretique de molecules au moyen de sondes immobilisees
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
FR2799988B1 (fr) 1999-10-26 2001-12-07 Centre Nat Rech Scient Procede de separation d'un compose chimique ou biologique dans un melange de composes similaires par diffusion dans un milieu tel qu'un gel
FR2806161B1 (fr) 2000-03-10 2002-09-20 Sebia Sa Methode de separation, d'identification et de quantification des isophosphatases alcalines par electrophorese
US8529744B2 (en) 2004-02-02 2013-09-10 Boreal Genomics Corp. Enrichment of nucleic acid targets
US8518228B2 (en) 2011-05-20 2013-08-27 The University Of British Columbia Systems and methods for enhanced SCODA
US9186685B2 (en) 2012-01-13 2015-11-17 The University Of British Columbia Multiple arm apparatus and methods for separation of particles
CA2552262C (fr) 2004-02-02 2016-04-19 The University Of British Columbia Scodaphorese, procedes et appareil utilises pour deplacer et concentrer des particules
US10337054B2 (en) 2004-02-02 2019-07-02 Quantum-Si Incorporated Enrichment of nucleic acid targets
US8475641B2 (en) 2008-02-01 2013-07-02 The University Of British Columbia Methods and apparatus for particle introduction and recovery
WO2010121381A1 (fr) 2009-04-21 2010-10-28 The University Of British Columbia Système et procédés pour la détection de particules
WO2013166444A2 (fr) 2012-05-04 2013-11-07 Boreal Genomics Corp. Analyse de biomarqueurs utilisant la scodaphorèse
US9340835B2 (en) 2013-03-15 2016-05-17 Boreal Genomics Corp. Method for separating homoduplexed and heteroduplexed nucleic acids
US11130986B2 (en) 2015-05-20 2021-09-28 Quantum-Si Incorporated Method for isolating target nucleic acid using heteroduplex binding proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5167790A (en) * 1985-09-27 1992-12-01 Washington University Field-inversion gel electrophoresis
GB9502660D0 (en) * 1995-02-10 1995-03-29 Univ London Detection of mutations or variations in DNA
WO1997045721A1 (fr) * 1996-05-24 1997-12-04 Novartis Ag Procede pour separer des melanges de substances au moyen d'une lectrophorese sur gel par affinite capillaire

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002350400A (ja) * 2001-05-29 2002-12-04 Aloka Co Ltd 電気泳動装置
JP4598989B2 (ja) * 2001-05-29 2010-12-15 アロカ株式会社 電気泳動装置
JP2007512509A (ja) * 2003-11-05 2007-05-17 エグザクト サイエンシーズ コーポレイション 反復的親和性分離およびその使用
JP2009516176A (ja) * 2005-11-10 2009-04-16 テラダイン、 インコーポレイテッド ローカルに順序付けられたストロービング
US8795494B2 (en) 2006-08-29 2014-08-05 Becton, Dickinson And Company Methods and apparatus for carrier-free deflection electrophoresis
JP2010508496A (ja) * 2006-08-29 2010-03-18 ベクトン・ディキンソン・アンド・カンパニー 無担体の偏向電気泳動の方法及び装置
US11369590B2 (en) 2007-08-17 2022-06-28 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US11298341B2 (en) 2007-08-17 2022-04-12 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US11717514B2 (en) 2007-08-17 2023-08-08 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
JP2010536790A (ja) * 2007-08-17 2010-12-02 パーデュー・リサーチ・ファウンデーション Ｐｓｍａ結合性リガンド−リンカー結合体及び使用方法
US10828282B2 (en) 2007-08-17 2020-11-10 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10046054B2 (en) 2007-08-17 2018-08-14 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US11083710B2 (en) 2007-08-17 2021-08-10 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US11318121B2 (en) 2007-08-17 2022-05-03 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10406240B2 (en) 2007-08-17 2019-09-10 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US8907058B2 (en) 2007-08-17 2014-12-09 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10485878B2 (en) 2007-08-17 2019-11-26 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10517957B2 (en) 2007-08-17 2019-12-31 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10517956B2 (en) 2007-08-17 2019-12-31 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10646581B2 (en) 2007-08-17 2020-05-12 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10624970B2 (en) 2007-08-17 2020-04-21 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10624971B2 (en) 2007-08-17 2020-04-21 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10624969B2 (en) 2007-08-17 2020-04-21 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US10557128B2 (en) 2010-02-25 2020-02-11 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US9951324B2 (en) 2010-02-25 2018-04-24 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US11155800B2 (en) 2010-02-25 2021-10-26 Purdue Research Foundation PSMA binding ligand-linker conjugates and methods for using
US9782493B2 (en) 2012-11-15 2017-10-10 Endocyte, Inc. Conjugates for treating diseases caused by PSMA expressing cells
US10912840B2 (en) 2012-11-15 2021-02-09 Endocyte, Inc. Conjugates for treating diseases caused by PSMA expressing cells
US9636413B2 (en) 2012-11-15 2017-05-02 Endocyte, Inc. Conjugates for treating diseases caused by PSMA expressing cells
US11045564B2 (en) 2013-10-18 2021-06-29 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (PSMA) as agents for the treatment of prostate cancer
US10471160B2 (en) 2013-10-18 2019-11-12 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
US10398791B2 (en) 2013-10-18 2019-09-03 Deutsches Krebsforschungszentrum Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
US11931430B2 (en) 2013-10-18 2024-03-19 Novartis Ag Labeled inhibitors of prostate specific membrane antigen (PSMA) as agents for the treatment of prostate cancer
US11951190B2 (en) 2013-10-18 2024-04-09 Novartis Ag Use of labeled inhibitors of prostate specific membrane antigen (PSMA), as agents for the treatment of prostate cancer
US10898596B2 (en) 2015-01-07 2021-01-26 Endocyte, Inc. Conjugates for imaging
US10188759B2 (en) 2015-01-07 2019-01-29 Endocyte, Inc. Conjugates for imaging

Also Published As

Publication number Publication date
WO1999045374A2 (fr) 1999-09-10
AU2896399A (en) 1999-09-20
EP1068518A2 (fr) 2001-01-17
CA2322975A1 (fr) 1999-09-10
WO1999045374A3 (fr) 2000-02-17

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