JP2002506204A - 可逆的アフィニティー電気泳動を用いる精製および検出プロセス - Google Patents
可逆的アフィニティー電気泳動を用いる精製および検出プロセスInfo
- Publication number
- JP2002506204A JP2002506204A JP2000534862A JP2000534862A JP2002506204A JP 2002506204 A JP2002506204 A JP 2002506204A JP 2000534862 A JP2000534862 A JP 2000534862A JP 2000534862 A JP2000534862 A JP 2000534862A JP 2002506204 A JP2002506204 A JP 2002506204A
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- electrophoretic medium
- electric field
- affinity ligand
- changed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
- G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7661498P | 1998-03-03 | 1998-03-03 | |
US60/076,614 | 1998-03-03 | ||
PCT/US1999/004849 WO1999045374A2 (fr) | 1998-03-03 | 1999-03-03 | Procedes de purification et de detection par electrophorese d'affinite reversible |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2002506204A true JP2002506204A (ja) | 2002-02-26 |
Family
ID=22133151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000534862A Pending JP2002506204A (ja) | 1998-03-03 | 1999-03-03 | 可逆的アフィニティー電気泳動を用いる精製および検出プロセス |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1068518A2 (fr) |
JP (1) | JP2002506204A (fr) |
AU (1) | AU2896399A (fr) |
CA (1) | CA2322975A1 (fr) |
WO (1) | WO1999045374A2 (fr) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002350400A (ja) * | 2001-05-29 | 2002-12-04 | Aloka Co Ltd | 電気泳動装置 |
JP2007512509A (ja) * | 2003-11-05 | 2007-05-17 | エグザクト サイエンシーズ コーポレイション | 反復的親和性分離およびその使用 |
JP2009516176A (ja) * | 2005-11-10 | 2009-04-16 | テラダイン、 インコーポレイテッド | ローカルに順序付けられたストロービング |
JP2010508496A (ja) * | 2006-08-29 | 2010-03-18 | ベクトン・ディキンソン・アンド・カンパニー | 無担体の偏向電気泳動の方法及び装置 |
JP2010536790A (ja) * | 2007-08-17 | 2010-12-02 | パーデュー・リサーチ・ファウンデーション | Psma結合性リガンド−リンカー結合体及び使用方法 |
US9636413B2 (en) | 2012-11-15 | 2017-05-02 | Endocyte, Inc. | Conjugates for treating diseases caused by PSMA expressing cells |
US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
US10398791B2 (en) | 2013-10-18 | 2019-09-03 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2289925A1 (fr) | 1997-05-16 | 1998-11-19 | Mosaic Technologies | Analyse electrophoretique de molecules au moyen de sondes immobilisees |
US6586177B1 (en) | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
FR2799988B1 (fr) * | 1999-10-26 | 2001-12-07 | Centre Nat Rech Scient | Procede de separation d'un compose chimique ou biologique dans un melange de composes similaires par diffusion dans un milieu tel qu'un gel |
FR2806161B1 (fr) | 2000-03-10 | 2002-09-20 | Sebia Sa | Methode de separation, d'identification et de quantification des isophosphatases alcalines par electrophorese |
US9186685B2 (en) | 2012-01-13 | 2015-11-17 | The University Of British Columbia | Multiple arm apparatus and methods for separation of particles |
US8529744B2 (en) | 2004-02-02 | 2013-09-10 | Boreal Genomics Corp. | Enrichment of nucleic acid targets |
US8518228B2 (en) | 2011-05-20 | 2013-08-27 | The University Of British Columbia | Systems and methods for enhanced SCODA |
US10337054B2 (en) | 2004-02-02 | 2019-07-02 | Quantum-Si Incorporated | Enrichment of nucleic acid targets |
EP1720636A4 (fr) | 2004-02-02 | 2012-06-20 | Univ British Columbia | Scodaphorese, procedes et appareil utilises pour deplacer et concentrer des particules |
US8475641B2 (en) | 2008-02-01 | 2013-07-02 | The University Of British Columbia | Methods and apparatus for particle introduction and recovery |
US8877028B2 (en) | 2009-04-21 | 2014-11-04 | The University Of British Columbia | System and methods for detection of particles |
WO2013166444A2 (fr) | 2012-05-04 | 2013-11-07 | Boreal Genomics Corp. | Analyse de biomarqueurs utilisant la scodaphorèse |
US9340835B2 (en) | 2013-03-15 | 2016-05-17 | Boreal Genomics Corp. | Method for separating homoduplexed and heteroduplexed nucleic acids |
US11130986B2 (en) | 2015-05-20 | 2021-09-28 | Quantum-Si Incorporated | Method for isolating target nucleic acid using heteroduplex binding proteins |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5167790A (en) * | 1985-09-27 | 1992-12-01 | Washington University | Field-inversion gel electrophoresis |
GB9502660D0 (en) * | 1995-02-10 | 1995-03-29 | Univ London | Detection of mutations or variations in DNA |
EP0901623B1 (fr) * | 1996-05-24 | 2004-06-30 | Zeptosens AG | Procede pour separer des melanges de substances au moyen d'une lectrophorese sur gel par affinite capillaire |
-
1999
- 1999-03-03 CA CA002322975A patent/CA2322975A1/fr not_active Abandoned
- 1999-03-03 WO PCT/US1999/004849 patent/WO1999045374A2/fr not_active Application Discontinuation
- 1999-03-03 AU AU28963/99A patent/AU2896399A/en not_active Abandoned
- 1999-03-03 JP JP2000534862A patent/JP2002506204A/ja active Pending
- 1999-03-03 EP EP99909853A patent/EP1068518A2/fr not_active Withdrawn
Cited By (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002350400A (ja) * | 2001-05-29 | 2002-12-04 | Aloka Co Ltd | 電気泳動装置 |
JP4598989B2 (ja) * | 2001-05-29 | 2010-12-15 | アロカ株式会社 | 電気泳動装置 |
JP2007512509A (ja) * | 2003-11-05 | 2007-05-17 | エグザクト サイエンシーズ コーポレイション | 反復的親和性分離およびその使用 |
JP2009516176A (ja) * | 2005-11-10 | 2009-04-16 | テラダイン、 インコーポレイテッド | ローカルに順序付けられたストロービング |
US8795494B2 (en) | 2006-08-29 | 2014-08-05 | Becton, Dickinson And Company | Methods and apparatus for carrier-free deflection electrophoresis |
JP2010508496A (ja) * | 2006-08-29 | 2010-03-18 | ベクトン・ディキンソン・アンド・カンパニー | 無担体の偏向電気泳動の方法及び装置 |
US11369590B2 (en) | 2007-08-17 | 2022-06-28 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US11298341B2 (en) | 2007-08-17 | 2022-04-12 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US11717514B2 (en) | 2007-08-17 | 2023-08-08 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
JP2010536790A (ja) * | 2007-08-17 | 2010-12-02 | パーデュー・リサーチ・ファウンデーション | Psma結合性リガンド−リンカー結合体及び使用方法 |
US10828282B2 (en) | 2007-08-17 | 2020-11-10 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10046054B2 (en) | 2007-08-17 | 2018-08-14 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US11083710B2 (en) | 2007-08-17 | 2021-08-10 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US11318121B2 (en) | 2007-08-17 | 2022-05-03 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10406240B2 (en) | 2007-08-17 | 2019-09-10 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US8907058B2 (en) | 2007-08-17 | 2014-12-09 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10485878B2 (en) | 2007-08-17 | 2019-11-26 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10517957B2 (en) | 2007-08-17 | 2019-12-31 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10517956B2 (en) | 2007-08-17 | 2019-12-31 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10646581B2 (en) | 2007-08-17 | 2020-05-12 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10624969B2 (en) | 2007-08-17 | 2020-04-21 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10624971B2 (en) | 2007-08-17 | 2020-04-21 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10624970B2 (en) | 2007-08-17 | 2020-04-21 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US10557128B2 (en) | 2010-02-25 | 2020-02-11 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US11155800B2 (en) | 2010-02-25 | 2021-10-26 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
US9782493B2 (en) | 2012-11-15 | 2017-10-10 | Endocyte, Inc. | Conjugates for treating diseases caused by PSMA expressing cells |
US10912840B2 (en) | 2012-11-15 | 2021-02-09 | Endocyte, Inc. | Conjugates for treating diseases caused by PSMA expressing cells |
US9636413B2 (en) | 2012-11-15 | 2017-05-02 | Endocyte, Inc. | Conjugates for treating diseases caused by PSMA expressing cells |
US11045564B2 (en) | 2013-10-18 | 2021-06-29 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (PSMA) as agents for the treatment of prostate cancer |
US10471160B2 (en) | 2013-10-18 | 2019-11-12 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
US10398791B2 (en) | 2013-10-18 | 2019-09-03 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
US11931430B2 (en) | 2013-10-18 | 2024-03-19 | Novartis Ag | Labeled inhibitors of prostate specific membrane antigen (PSMA) as agents for the treatment of prostate cancer |
US11951190B2 (en) | 2013-10-18 | 2024-04-09 | Novartis Ag | Use of labeled inhibitors of prostate specific membrane antigen (PSMA), as agents for the treatment of prostate cancer |
US10898596B2 (en) | 2015-01-07 | 2021-01-26 | Endocyte, Inc. | Conjugates for imaging |
US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
Also Published As
Publication number | Publication date |
---|---|
WO1999045374A2 (fr) | 1999-09-10 |
CA2322975A1 (fr) | 1999-09-10 |
AU2896399A (en) | 1999-09-20 |
EP1068518A2 (fr) | 2001-01-17 |
WO1999045374A3 (fr) | 2000-02-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060303 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090313 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090903 |