JP2002503683A5 - - Google Patents

Download PDF

Info

Publication number
JP2002503683A5
JP2002503683A5 JP2000532093A JP2000532093A JP2002503683A5 JP 2002503683 A5 JP2002503683 A5 JP 2002503683A5 JP 2000532093 A JP2000532093 A JP 2000532093A JP 2000532093 A JP2000532093 A JP 2000532093A JP 2002503683 A5 JP2002503683 A5 JP 2002503683A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
seq
patient
dna
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000532093A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002503683A (ja
Filing date
Publication date
Priority claimed from US09/072,967 external-priority patent/US6592877B1/en
Application filed filed Critical
Publication of JP2002503683A publication Critical patent/JP2002503683A/ja
Publication of JP2002503683A5 publication Critical patent/JP2002503683A5/ja
Withdrawn legal-status Critical Current

Links

JP2000532093A 1998-02-18 1999-02-17 結核の免疫療法および診断のための化合物および方法 Withdrawn JP2002503683A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2519798A 1998-02-18 1998-02-18
US09/025,197 1998-02-18
US09/072,967 1998-05-05
US09/072,967 US6592877B1 (en) 1995-09-01 1998-05-05 Compounds and methods for immunotherapy and diagnosis of tuberculosis
PCT/US1999/003268 WO1999042076A2 (en) 1998-02-18 1999-02-17 Compounds and methods for immunotherapy and diagnosis of tuberculosis

Publications (2)

Publication Number Publication Date
JP2002503683A JP2002503683A (ja) 2002-02-05
JP2002503683A5 true JP2002503683A5 (enExample) 2006-04-06

Family

ID=26699420

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000532093A Withdrawn JP2002503683A (ja) 1998-02-18 1999-02-17 結核の免疫療法および診断のための化合物および方法

Country Status (6)

Country Link
US (6) US6592877B1 (enExample)
EP (1) EP1071451A4 (enExample)
JP (1) JP2002503683A (enExample)
AU (1) AU2766399A (enExample)
CA (1) CA2337638A1 (enExample)
WO (1) WO1999042076A2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
DE69941545D1 (de) * 1998-11-04 2009-11-26 Isis Innovation Tuberkulose diagnose test
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1517913B9 (en) * 1999-10-07 2007-08-29 Corixa Corporation A mycobacterium tuberculosis coding sequence for exression of heterologous proteins
US7009042B1 (en) 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
EP1229931A4 (en) * 1999-10-07 2003-05-28 Corixa Corp FUSION PROTEINS FROM MYCOBACTERIUM TUBERCULOSIS
WO2001062893A2 (en) 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
PT2133100E (pt) 2000-06-20 2012-01-11 Corixa Corp Antigénio mtb32a de mycobacterium tuberculosis com um local activo inactivado e suas proteínas de fusão
AU2003213118A1 (en) * 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US20040175341A1 (en) * 2003-03-04 2004-09-09 Manning Monna Marie Microemulsion for cosmetic or pharmaceutical use containing an active ingredient
ITRM20040091A1 (it) 2004-02-19 2004-05-19 Istituto Naz Per Le Malattie Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
US8475735B2 (en) * 2004-11-01 2013-07-02 Uma Mahesh Babu Disposable immunodiagnostic test system
BRPI0518933A2 (pt) 2004-11-16 2008-12-16 Crucell Holland B V E Aeras Gl adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium
WO2006060484A2 (en) * 2004-12-01 2006-06-08 Gene Therapy Systems, Inc. Tuberculosis nucleic acids, polypeptides and immunogenic compositions
US20060292647A1 (en) * 2004-12-03 2006-12-28 Green Lawrence R Reflex supplemental testing - A rapid, efficient and highly accurate method to identify subjects with an infection, disease or other condition
US20080124738A1 (en) * 2005-03-01 2008-05-29 Pritest, Inc Compositions and methods of testing for tuberculosis and mycobacterium infection
EP2305701A1 (en) 2005-07-01 2011-04-06 Forsyth Dental Infirmary for Children Tuberculosis antigen detection assays and vaccines
US7713715B2 (en) * 2005-09-06 2010-05-11 University Of Tennessee Research Foundation Method for diagnosing infections
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
CN100999550B (zh) * 2006-01-10 2010-10-06 中国人民解放军第三○九医院 结核分枝杆菌融合蛋白及其应用
GB0618127D0 (en) * 2006-09-14 2006-10-25 Isis Innovation Biomarker
EP2087128A4 (en) 2006-11-01 2009-11-04 Immport Therapeutics Inc COMPOSITIONS AND METHODS FOR IMMUNOMINANT ANTIGENES
RU2312673C1 (ru) * 2006-11-24 2007-12-20 Людмила Анатольевна Шовкун Способ лечения больных туберкулезом легких
WO2008124647A2 (en) 2007-04-04 2008-10-16 Infectious Disease Research Institute Immunogenic compositions comprising mycobacterium tuberculosis polypeptides and fusions thereof
HRP20181353T1 (hr) 2008-07-25 2018-10-19 Glaxosmithkline Biologicals S.A. Tuberkulozni protein rv2386c, njegovi pripravci i upotreba
NO2315597T3 (enExample) 2008-07-25 2018-01-20
LT2528621T (lt) 2010-01-27 2016-12-12 Glaxosmithkline Biologicals S.A. Modifikuoti tuberkuliozės antigenai
WO2012031752A2 (en) * 2010-09-07 2012-03-15 Institut Pasteur Korea Tuberculosis mutants
PL2844282T3 (pl) * 2012-05-04 2019-11-29 Pfizer Antygeny związane z gruczołem krokowym i schematy immunoterapii oparte na szczepionce
KR101665849B1 (ko) * 2015-01-29 2016-10-12 사단법인대한결핵협회 결핵감염 진단을 위한 항원 펩타이드 조성물 및 이의 용도

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5856073A (en) 1973-06-28 1975-01-30 Toru Tsumits Tuberculin active proteins and peptides
FR2244539A1 (en) 1973-07-13 1975-04-18 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
FR2265402A1 (en) 1974-03-29 1975-10-24 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
US4235877A (en) * 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4769330A (en) * 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4866034A (en) * 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4876089A (en) * 1984-09-06 1989-10-24 Chiron Corporation Feline leukemia virus protein vaccines
US4751180A (en) * 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4689397A (en) * 1985-08-12 1987-08-25 Scripps Clinic And Research Foundation Synthetic polypeptides for detecting mycobacterial infections
US4777127A (en) * 1985-09-30 1988-10-11 Labsystems Oy Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
US4935233A (en) * 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4877611A (en) * 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
EP0345299A1 (en) 1987-02-02 1989-12-13 Whitehead Institute For Biomedical Research Mycobacterium tuberculosis genes encoding protein antigens
GB8702816D0 (en) 1987-02-07 1987-03-11 Al Sumidaie A M K Obtaining retrovirus-containing fraction
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US4952395A (en) * 1987-02-26 1990-08-28 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US5504005A (en) * 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5583112A (en) * 1987-05-29 1996-12-10 Cambridge Biotech Corporation Saponin-antigen conjugates and the use thereof
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
AP129A (en) 1988-06-03 1991-04-17 Smithkline Biologicals S A Expression of retrovirus gag protein eukaryotic cells
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5108745B1 (en) 1988-08-16 1998-06-30 Univ California Tuberculosis and legionellosis vaccines and methods for their production
US5549910A (en) * 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
CA2042016C (en) 1989-09-19 2004-04-06 Jean Content Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
EP0419355B1 (en) 1989-09-19 2000-02-09 N.V. Innogenetics S.A. Recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnostic of tuberculosis
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
SE9001105D0 (sv) 1990-03-27 1990-03-27 Astra Ab New methods foer diagnosis of tuberculosis
US5466468A (en) * 1990-04-03 1995-11-14 Ciba-Geigy Corporation Parenterally administrable liposome formulation comprising synthetic lipids
WO1992008488A1 (en) * 1990-11-08 1992-05-29 University College London Mycobacterium as adjuvant for antigens
JP3218637B2 (ja) * 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
AU650065B2 (en) 1990-09-06 1994-06-09 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Inhibitor of lymphocyte response and immune-related disease
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
EP0499003A1 (en) 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
GB9105446D0 (en) 1991-03-14 1991-05-01 British Bio Technology Proteins and nucleic acids
DE69231519T2 (de) 1991-03-25 2001-05-31 N.V. Innogenetics S.A., Gent Polypeptide aus micobakterium paratuberculosis
RU2024021C1 (ru) 1991-05-05 1994-11-30 Научно-исследовательский институт хирургии Восточно-Сибирского филиала СО РАМН Способ диагностики туберкулеза
DE4116249A1 (de) 1991-05-17 1992-11-19 Biotechnolog Forschung Gmbh Hybrid-plasmid fuer m.-tuberculosis-antigen, e. coli als wirt und antigen
GB9111291D0 (en) 1991-05-24 1991-07-17 Medical Res Council Diagnostic peptides
FR2677365B1 (fr) 1991-06-07 1995-08-04 Pasteur Institut Proteines de mycobacterium et applications.
US5240856A (en) * 1991-10-23 1993-08-31 Cellpro Incorporated Apparatus for cell separation
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
ATE155681T1 (de) * 1992-05-18 1997-08-15 Minnesota Mining & Mfg Einrichtung zur transmucosalen wirkstoffabgabe
WO1994000492A1 (en) 1992-06-24 1994-01-06 Washington State University Research Foundation Angiotensin iv peptides and receptor
US5330754A (en) * 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
NL9202197A (nl) * 1992-12-17 1994-07-18 Kreatech Biotech Bv Werkwijze en inrichting voor het identificeren van een voor een mycobacteriële infectie verantwoordelijk mycobacterium species.
DE69418699T2 (de) * 1993-01-11 1999-09-30 Dana-Farber Cancer Institute, Boston Induktion der antworten zytotoxischer t-lymphozyten
US5616500A (en) * 1993-04-30 1997-04-01 The United States Of America As Represented By The Department Of Health & Human Services Trichohyalin and transglutaminase-3 and methods of using same
DK79793D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test
US5955077A (en) * 1993-07-02 1999-09-21 Statens Seruminstitut Tuberculosis vaccine
DK79893D0 (da) 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine
US5639653A (en) * 1993-07-19 1997-06-17 Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva Universtiy Method for proliferating Vγ2Vδ2 T cells
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
JPH09505588A (ja) 1993-11-23 1997-06-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 多くの細胞外生成物及びそれらの製造法並びに使用
US5783386A (en) 1994-02-24 1998-07-21 Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd. Mycobacteria virulence factors and a novel method for their identification
GB9409985D0 (en) 1994-05-18 1994-07-06 Medical Res Council Vaccine against mycobacterial infections
US5616432A (en) 1994-06-14 1997-04-01 Ovonic Battery Company, Inc. Electrochemical hydrogen storage alloys and batteries fabricated from Mg containing base alloys
US5736524A (en) 1994-11-14 1998-04-07 Merck & Co.,. Inc. Polynucleotide tuberculosis vaccine
DE4446509A1 (de) * 1994-12-24 1996-06-27 Sel Alcatel Ag Verfahren zur Herstellung von Leiterbahnen auf einem Vertiefungen aufweisenden Substrat
US5795587A (en) * 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US5714593A (en) 1995-02-01 1998-02-03 Institut Pasteur DNA from mycobacterium tuberculosis which codes for a 45/47 kilodalton protein
US5580579A (en) * 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
AU706367B2 (en) 1995-03-13 1999-06-17 Astra Aktiebolag New DNA molecules
US5817476A (en) * 1995-06-07 1998-10-06 Genetics Institute, Inc. Polynucleotides encoding interleukin-1 receptor intracellular ligand proteins
US6458366B1 (en) * 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
CA2230276A1 (en) 1995-09-01 1997-03-13 Mitsui Petrochemical Industries, Ltd. Casing enclosed type magnetic core
EP1203817B9 (en) 1995-09-01 2006-08-16 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6338852B1 (en) * 1995-09-01 2002-01-15 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
MX9801687A (es) 1995-09-01 1998-11-29 Corixa Corp Compuestos y metodos para el diagnostico de tuberculosis.
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
CO4600637A1 (es) * 1996-03-15 1998-05-08 Corixa Corp Compuestos para inmunoterapia e inmunodiagnosis del cancer de prostata
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US5985287A (en) * 1996-08-29 1999-11-16 Genesis Research And Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
US5856462A (en) * 1996-09-10 1999-01-05 Hybridon Incorporated Oligonucleotides having modified CpG dinucleosides
US6350456B1 (en) * 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6627198B2 (en) * 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6544522B1 (en) * 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6113918A (en) * 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6355257B1 (en) * 1997-05-08 2002-03-12 Corixa Corporation Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US6555653B2 (en) * 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
BR9909472A (pt) * 1998-04-07 2001-09-11 Corixa Corp Polipeptìdeo purificado, processo para prevenir tuberculose, e, composição farmacêutica
US6465633B1 (en) * 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
EP1229931A4 (en) * 1999-10-07 2003-05-28 Corixa Corp FUSION PROTEINS FROM MYCOBACTERIUM TUBERCULOSIS
WO2001062893A2 (en) * 2000-02-25 2001-08-30 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
PT2133100E (pt) * 2000-06-20 2012-01-11 Corixa Corp Antigénio mtb32a de mycobacterium tuberculosis com um local activo inactivado e suas proteínas de fusão
AU2003213118A1 (en) * 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis

Similar Documents

Publication Publication Date Title
CA2230885A1 (en) Compounds and methods for immunotherapy and diagnosis of tuberculosis
JP2006149406A5 (enExample)
JP2006187292A5 (enExample)
JP2006501825A5 (enExample)
IL133056A (en) Polypeptide containing an immunogenic portion of an m. tuberculosis antigen, a variant thereof and pharmaceutical compositions containing same
NZ334358A (en) isolated polypeptide comprising an immunogenic portion of a M vaccine antigen, use in the treatment and diagnosis of mycobacterial infections
JP2001081042A5 (enExample)
JP2002542827A5 (enExample)
JP2004511201A5 (enExample)
CA2195955A1 (en) Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
CA2224127A1 (en) Flagellin gene, flac of campylobacter
CA2405247A1 (en) Tuberculosis antigens and methods of use thereof
JP2004531242A5 (enExample)
JP2009149642A (ja) ヘモフィルス・インフルエンゼ抗原及び対応ｄｎａ断片
JP2002512800A5 (enExample)
JP2005512518A5 (enExample)
JP2002512005A5 (enExample)
Musso et al. Sequence of quinolone resistance-determining region of gyrA gene for clinical isolates and for an in vitro-selected quinolone-resistant strain of Coxiella burnetii
JP2002516662A5 (enExample)
US6605287B2 (en) Vaccines for Chlamydia psittaci infections
JP2004513615A5 (enExample)
CA2223503A1 (en) Transferrin receptor genes
US20030007976A1 (en) Methods and compounds for the treatment of immunologically-mediated skin disorders
US6660275B2 (en) Chlamydia antigens and corresponding DNA fragments and uses thereof
JP4374245B2 (ja) グループｂ連鎖球菌の抗原及び対応するｄｎａ断片