JP2002503459A5 - - Google Patents
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- JP2002503459A5 JP2002503459A5 JP2000531540A JP2000531540A JP2002503459A5 JP 2002503459 A5 JP2002503459 A5 JP 2002503459A5 JP 2000531540 A JP2000531540 A JP 2000531540A JP 2000531540 A JP2000531540 A JP 2000531540A JP 2002503459 A5 JP2002503459 A5 JP 2002503459A5
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- JP
- Japan
- Prior art keywords
- fiber
- protein
- adenovirus
- gene
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7484498P | 1998-02-17 | 1998-02-17 | |
| US60/074,844 | 1998-02-17 | ||
| PCT/US1999/003233 WO1999041359A1 (en) | 1998-02-17 | 1999-02-16 | Modified adenovirus containing a fiber replacement protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002503459A JP2002503459A (ja) | 2002-02-05 |
| JP2002503459A5 true JP2002503459A5 (enExample) | 2006-04-06 |
Family
ID=22122019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000531540A Pending JP2002503459A (ja) | 1998-02-17 | 1999-02-16 | 繊維置換タンパク質を含有する修飾されたアデノウィルス |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6210946B1 (enExample) |
| EP (1) | EP1070118B1 (enExample) |
| JP (1) | JP2002503459A (enExample) |
| KR (1) | KR20010074429A (enExample) |
| CN (1) | CN1297479A (enExample) |
| AT (1) | ATE342350T1 (enExample) |
| AU (1) | AU751542B2 (enExample) |
| BR (1) | BR9908018A (enExample) |
| CA (1) | CA2321135A1 (enExample) |
| DE (1) | DE69933550T2 (enExample) |
| IL (1) | IL137730A0 (enExample) |
| NO (1) | NO20004563L (enExample) |
| NZ (1) | NZ506451A (enExample) |
| WO (1) | WO1999041359A1 (enExample) |
| ZA (1) | ZA200004208B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6815200B1 (en) * | 1998-02-17 | 2004-11-09 | The Uab Research Foundation | Modified adenovirus containing a fiber replacement protein |
| US20050095231A1 (en) * | 1998-02-17 | 2005-05-05 | Curiel David T. | Modified adenovirus containing a fiber replacement protein |
| WO1999055365A1 (en) | 1998-04-30 | 1999-11-04 | Cornell Research Foundation, Inc. | Adenoviral vectors with tandem fiber proteins |
| AU767975B2 (en) | 1998-09-11 | 2003-11-27 | Genvec, Inc. | Alternatively targeted adenovirus |
| AU2869300A (en) * | 1999-02-05 | 2000-08-25 | Uab Research Foundation, The | Fiber receptor-independent system for the propagation of adenoviral vectors |
| KR20020092886A (ko) * | 1999-07-06 | 2002-12-12 | 고트-아-겐 에이비 | 재조합 아데노바이러스 |
| WO2001081607A2 (en) * | 2000-04-26 | 2001-11-01 | Crucell Holland B.V. | Adenovirus vectors with knobless fibers, and their uses |
| US7332337B2 (en) * | 2000-05-16 | 2008-02-19 | Galapagos Nv | Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells |
| JP3635462B2 (ja) * | 2000-05-31 | 2005-04-06 | 国立医薬品食品衛生研究所長 | アデノウイルスベクター |
| EP1285079A2 (en) * | 2000-05-31 | 2003-02-26 | University of Saskatchewan | Modified bovine adenovirus having altered tropism |
| GB0017720D0 (en) * | 2000-07-19 | 2000-09-06 | Got A Gene Ab | Modified virus |
| ES2375557T3 (es) * | 2001-06-22 | 2012-03-02 | The Trustees Of The University Of Pennsylvania | Adenovirus recombinantes que comprenden prote�?nas de adenovirus de simios y usos de los mismos. |
| US6905678B2 (en) | 2001-07-07 | 2005-06-14 | Crucell Holland B.V. | Gene delivery vectors with cell type specificity for mesenchymal stem cells |
| JP4488290B2 (ja) * | 2002-01-24 | 2010-06-23 | ザ・スクリップス・リサーチ・インスティテュート | 効率的ターゲティングのためのファイバーシャフト変異 |
| AU2003259199A1 (en) * | 2002-07-22 | 2004-02-09 | Vectorlogics, Inc. | Adenoviral vector incorporating zipper peptide-modified fiber protein and uses thereof |
| US20050003548A1 (en) * | 2002-07-22 | 2005-01-06 | Nikolay Korokhov | Targeted adenoviral vector displaying immunoglobulin-binding domain and uses thereof |
| EP1542731A4 (en) * | 2002-07-22 | 2006-03-01 | Vectorlogics Inc | TARGETED ADENOVIRAL VECTOR DISPLAYING IMMUNOGLOBULIN BINDING DOMAIN AND ITS USES |
| EP1625222A2 (en) | 2003-05-14 | 2006-02-15 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Broadening adenovirus tropism |
| WO2004111251A2 (en) * | 2003-06-11 | 2004-12-23 | The Scripps Research Institute | Modified fiber proteins for efficient receptor binding |
| US7291498B2 (en) | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| JP6499825B2 (ja) | 2010-06-10 | 2019-04-10 | ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャリゼーション | デスモグレイン２（ｄｓｇ２）とのアデノウイルスの相互作用のための方法およびシステム |
| JP6576326B2 (ja) | 2013-03-14 | 2019-09-18 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍溶解性アデノウイルス組成物 |
| WO2015161314A1 (en) | 2014-04-18 | 2015-10-22 | Washington University | Adenoviral targeting, compositions and methods therefor |
| CN107683289B (zh) * | 2015-01-26 | 2021-08-06 | 芝加哥大学 | IL13Rα2结合剂和其在癌症治疗中的用途 |
| AU2017222568B2 (en) | 2016-02-23 | 2020-09-10 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| KR20220163505A (ko) | 2016-02-23 | 2022-12-09 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| AU2017375633C1 (en) | 2016-12-12 | 2023-04-27 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| WO2018118967A1 (en) | 2016-12-21 | 2018-06-28 | Memgen, Llc | Armed replication-competent oncolytic adenoviruses |
| CN112292449A (zh) | 2018-04-09 | 2021-01-29 | 萨克生物研究学院 | 具有增强的复制特性的溶瘤腺病毒组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9223084D0 (en) * | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
| US5543328A (en) * | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
| US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| US5871727A (en) * | 1995-12-08 | 1999-02-16 | Uab Research Foundation | Targeted adenovirus vectors |
| US5877011A (en) * | 1996-11-20 | 1999-03-02 | Genzyme Corporation | Chimeric adenoviral vectors |
-
1999
- 1999-02-16 KR KR1020007008959A patent/KR20010074429A/ko not_active Withdrawn
- 1999-02-16 EP EP99932506A patent/EP1070118B1/en not_active Expired - Lifetime
- 1999-02-16 BR BR9908018-4A patent/BR9908018A/pt not_active IP Right Cessation
- 1999-02-16 AT AT99932506T patent/ATE342350T1/de not_active IP Right Cessation
- 1999-02-16 DE DE69933550T patent/DE69933550T2/de not_active Expired - Lifetime
- 1999-02-16 IL IL13773098A patent/IL137730A0/xx unknown
- 1999-02-16 NZ NZ506451A patent/NZ506451A/xx unknown
- 1999-02-16 CA CA002321135A patent/CA2321135A1/en not_active Abandoned
- 1999-02-16 JP JP2000531540A patent/JP2002503459A/ja active Pending
- 1999-02-16 CN CN99805041A patent/CN1297479A/zh active Pending
- 1999-02-16 US US09/250,580 patent/US6210946B1/en not_active Expired - Lifetime
- 1999-02-16 AU AU32940/99A patent/AU751542B2/en not_active Ceased
- 1999-02-16 WO PCT/US1999/003233 patent/WO1999041359A1/en not_active Ceased
-
2000
- 2000-08-17 ZA ZA200004208A patent/ZA200004208B/en unknown
- 2000-09-13 NO NO20004563A patent/NO20004563L/no unknown
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