JP2002502666A - 延伸結晶性エラストマーの医療用インプラントおよび移植方法 - Google Patents
延伸結晶性エラストマーの医療用インプラントおよび移植方法Info
- Publication number
- JP2002502666A JP2002502666A JP2000531135A JP2000531135A JP2002502666A JP 2002502666 A JP2002502666 A JP 2002502666A JP 2000531135 A JP2000531135 A JP 2000531135A JP 2000531135 A JP2000531135 A JP 2000531135A JP 2002502666 A JP2002502666 A JP 2002502666A
- Authority
- JP
- Japan
- Prior art keywords
- implant
- stretched
- lens
- medical implant
- stretched crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 title claims abstract description 290
- 238000000034 method Methods 0.000 title claims abstract description 56
- 238000002513 implantation Methods 0.000 title claims abstract description 50
- 229920001971 elastomer Polymers 0.000 title claims description 51
- 239000000806 elastomer Substances 0.000 title claims description 48
- 208000014674 injury Diseases 0.000 claims abstract description 7
- 238000003780 insertion Methods 0.000 claims abstract description 7
- 230000037431 insertion Effects 0.000 claims abstract description 7
- 230000008733 trauma Effects 0.000 claims abstract description 7
- 229920002379 silicone rubber Polymers 0.000 claims abstract description 6
- 229920001577 copolymer Polymers 0.000 claims description 27
- 238000002425 crystallisation Methods 0.000 claims description 27
- 230000008025 crystallization Effects 0.000 claims description 27
- 230000003287 optical effect Effects 0.000 claims description 27
- 238000001816 cooling Methods 0.000 claims description 18
- 229920001296 polysiloxane Polymers 0.000 claims description 17
- 238000007906 compression Methods 0.000 claims description 13
- 230000006835 compression Effects 0.000 claims description 13
- 230000006870 function Effects 0.000 claims description 13
- 238000011084 recovery Methods 0.000 claims description 12
- 239000002178 crystalline material Substances 0.000 claims description 10
- 229920001519 homopolymer Polymers 0.000 claims description 9
- -1 methyl (3,3,3-trifluoropropyl) siloxane Chemical class 0.000 claims description 8
- VCYDUTCMKSROID-UHFFFAOYSA-N 2,2,4,4,6,6-hexakis-phenyl-1,3,5,2,4,6-trioxatrisilinane Chemical compound O1[Si](C=2C=CC=CC=2)(C=2C=CC=CC=2)O[Si](C=2C=CC=CC=2)(C=2C=CC=CC=2)O[Si]1(C=1C=CC=CC=1)C1=CC=CC=C1 VCYDUTCMKSROID-UHFFFAOYSA-N 0.000 claims description 5
- 230000001976 improved effect Effects 0.000 claims description 2
- 230000013011 mating Effects 0.000 claims description 2
- 230000035807 sensation Effects 0.000 claims description 2
- 238000002054 transplantation Methods 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
- 230000036760 body temperature Effects 0.000 abstract description 21
- 208000002847 Surgical Wound Diseases 0.000 abstract description 17
- 239000013536 elastomeric material Substances 0.000 abstract description 9
- 210000000695 crystalline len Anatomy 0.000 description 143
- 239000000463 material Substances 0.000 description 46
- 238000006243 chemical reaction Methods 0.000 description 28
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 27
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 27
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 27
- 239000000178 monomer Substances 0.000 description 24
- 238000002844 melting Methods 0.000 description 22
- 230000008018 melting Effects 0.000 description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 12
- 230000008569 process Effects 0.000 description 11
- 230000008901 benefit Effects 0.000 description 10
- 239000013078 crystal Substances 0.000 description 10
- 230000000704 physical effect Effects 0.000 description 10
- XSDCTSITJJJDPY-UHFFFAOYSA-N chloro-ethenyl-dimethylsilane Chemical compound C[Si](C)(Cl)C=C XSDCTSITJJJDPY-UHFFFAOYSA-N 0.000 description 9
- 239000012153 distilled water Substances 0.000 description 9
- 239000000203 mixture Substances 0.000 description 9
- 229920000642 polymer Polymers 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 8
- 238000005406 washing Methods 0.000 description 8
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 6
- 230000009467 reduction Effects 0.000 description 6
- 230000001588 bifunctional effect Effects 0.000 description 5
- 239000000017 hydrogel Substances 0.000 description 5
- 239000003999 initiator Substances 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 238000001556 precipitation Methods 0.000 description 5
- 230000035484 reaction time Effects 0.000 description 5
- 229910052786 argon Inorganic materials 0.000 description 4
- 235000010290 biphenyl Nutrition 0.000 description 4
- 239000004305 biphenyl Substances 0.000 description 4
- 238000004132 cross linking Methods 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- 230000001965 increasing effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 230000005499 meniscus Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 229910052697 platinum Inorganic materials 0.000 description 3
- 230000001376 precipitating effect Effects 0.000 description 3
- 230000006641 stabilisation Effects 0.000 description 3
- 238000011105 stabilization Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000004971 Cross linker Substances 0.000 description 2
- MZRVEZGGRBJDDB-UHFFFAOYSA-N N-Butyllithium Chemical compound [Li]CCCC MZRVEZGGRBJDDB-UHFFFAOYSA-N 0.000 description 2
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 210000002159 anterior chamber Anatomy 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 239000003054 catalyst Substances 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000007334 copolymerization reaction Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000007872 degassing Methods 0.000 description 2
- UOUILILVWRHZSH-UHFFFAOYSA-N dimethyl-tris[(dimethyl-$l^{3}-silanyl)oxy]silyloxysilicon Chemical compound C[Si](C)O[Si](O[Si](C)C)(O[Si](C)C)O[Si](C)C UOUILILVWRHZSH-UHFFFAOYSA-N 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 239000013081 microcrystal Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229920000438 poly[methyl(3,3,3-trifluoropropyl)siloxane] polymer Polymers 0.000 description 2
- 230000000379 polymerizing effect Effects 0.000 description 2
- 239000012763 reinforcing filler Substances 0.000 description 2
- 210000001525 retina Anatomy 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 208000002197 Ehlers-Danlos syndrome Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000002730 additional effect Effects 0.000 description 1
- 201000009310 astigmatism Diseases 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 244000221110 common millet Species 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- SYZWSSNHPZXGML-UHFFFAOYSA-N dichloromethane;oxolane Chemical compound ClCCl.C1CCOC1 SYZWSSNHPZXGML-UHFFFAOYSA-N 0.000 description 1
- OLLFKUHHDPMQFR-UHFFFAOYSA-N dihydroxy(diphenyl)silane Chemical compound C=1C=CC=CC=1[Si](O)(O)C1=CC=CC=C1 OLLFKUHHDPMQFR-UHFFFAOYSA-N 0.000 description 1
- 210000005069 ears Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 229920001198 elastomeric copolymer Polymers 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 229910021485 fumed silica Inorganic materials 0.000 description 1
- 229940089982 healon Drugs 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002406 microsurgery Methods 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 230000006461 physiological response Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 210000000216 zygoma Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/023,391 | 1998-02-13 | ||
| US09/023,391 US6030416A (en) | 1998-02-13 | 1998-02-13 | Medical implants of stretch-crystallizable elastomers and methods of implantation |
| PCT/US1999/003090 WO1999040877A1 (en) | 1998-02-13 | 1999-02-12 | Medical implants of stretch-crystallizable elastomers and methods of implantation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002502666A true JP2002502666A (ja) | 2002-01-29 |
| JP2002502666A5 JP2002502666A5 (https=) | 2006-02-23 |
Family
ID=21814815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000531135A Pending JP2002502666A (ja) | 1998-02-13 | 1999-02-12 | 延伸結晶性エラストマーの医療用インプラントおよび移植方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6030416A (https=) |
| EP (1) | EP1056415B1 (https=) |
| JP (1) | JP2002502666A (https=) |
| KR (1) | KR20010052169A (https=) |
| CN (1) | CN1226971C (https=) |
| AT (1) | ATE241328T1 (https=) |
| AU (1) | AU748650B2 (https=) |
| BR (1) | BR9907757A (https=) |
| CA (1) | CA2317746C (https=) |
| DE (1) | DE69908307T2 (https=) |
| DK (1) | DK1056415T3 (https=) |
| ES (1) | ES2200502T3 (https=) |
| HU (1) | HUP0100231A3 (https=) |
| IL (1) | IL137807A (https=) |
| NO (1) | NO318248B1 (https=) |
| NZ (1) | NZ505585A (https=) |
| PL (1) | PL342842A1 (https=) |
| PT (1) | PT1056415E (https=) |
| RU (1) | RU2220681C2 (https=) |
| SK (1) | SK11282000A3 (https=) |
| TR (1) | TR200002259T2 (https=) |
| WO (1) | WO1999040877A1 (https=) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003534070A (ja) * | 2000-05-22 | 2003-11-18 | メデニアム インコーポレーテッド | 眼用装置のための結晶性ポリマー組成物 |
| WO2014027689A1 (ja) * | 2012-08-17 | 2014-02-20 | Hoya株式会社 | 眼内レンズ用部材及び眼内レンズ |
| JP2014036769A (ja) * | 2012-08-17 | 2014-02-27 | Hoya Corp | 眼内レンズ用部材及び眼内レンズ |
| JP2014036770A (ja) * | 2012-08-17 | 2014-02-27 | Hoya Corp | 眼内レンズ用部材及び眼内レンズ |
| JP2014525759A (ja) * | 2011-05-23 | 2014-10-02 | カリフォルニア インスティチュート オブ テクノロジー | 調節性眼内レンズ |
| JP2019118689A (ja) * | 2018-01-09 | 2019-07-22 | 株式会社ニデック | 眼内レンズ挿入器具および眼内レンズ挿入システム |
| US12295831B2 (en) | 2023-10-23 | 2025-05-13 | California Institute Of Technology | Liquid accommodating intraocular lens with an asymmetric chamber |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180687B1 (en) | 1996-04-08 | 2001-01-30 | Alcon Laboratories, Inc. | In vivo polymerizable ophthalmic compositions and methods of using |
| SE0001352D0 (sv) * | 2000-04-12 | 2000-04-12 | Pharmacia & Upjohn Bv | Injectable intraocular accommodating lens |
| US20050277864A1 (en) * | 2000-04-14 | 2005-12-15 | David Haffner | Injectable gel implant for glaucoma treatment |
| US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
| US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
| DE60015614T2 (de) * | 2000-08-04 | 2005-11-10 | Medennium, Inc., Irvine | Okularpfropf für tränenpunkt und intrakanalikuläres implantat |
| US6550480B2 (en) | 2001-01-31 | 2003-04-22 | Numed/Tech Llc | Lumen occluders made from thermodynamic materials |
| WO2002080811A2 (en) | 2001-04-07 | 2002-10-17 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
| US7331984B2 (en) | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
| US6733526B2 (en) | 2002-04-25 | 2004-05-11 | Advanced Medical Optics, Inc. | Method of improving adherence and centering of intra-corneal implants on corneal bed |
| US20050043796A1 (en) * | 2003-07-01 | 2005-02-24 | Grant Richard L. | Spinal disc nucleus implant |
| EP2193812A1 (en) * | 2003-09-19 | 2010-06-09 | Broockeville Corporation N.V. | Use of a curable elastomer-precursor for a medical treatment |
| US7597660B2 (en) * | 2003-09-19 | 2009-10-06 | Broockeville Corporation B.V. | Incontinence therapy |
| US20050107873A1 (en) * | 2003-11-18 | 2005-05-19 | Medennium, Inc. | Accommodative intraocular lens and method of implantation |
| US20050209695A1 (en) * | 2004-03-15 | 2005-09-22 | De Vries Jan A | Vertebroplasty method |
| US20050228216A1 (en) * | 2004-04-08 | 2005-10-13 | Vries Jan A D | Method for treating gastroesophageal reflux disease |
| US8501645B2 (en) * | 2005-06-30 | 2013-08-06 | Donna K. Jackson | Enhanced filamentous silicone products and processes |
| WO2008061043A2 (en) | 2006-11-10 | 2008-05-22 | Glaukos Corporation | Uveoscleral shunt and methods for implanting same |
| JP5520417B2 (ja) * | 2010-04-22 | 2014-06-11 | シュリカント ミルライ ラム | 改良された眼内レンズ注入デバイス |
| EP2654715B1 (en) | 2010-11-24 | 2017-01-25 | Dose Medical Corporation | Drug eluting ocular implant |
| EP3342380B1 (en) | 2012-03-26 | 2024-12-04 | Glaukos Corporation | System for delivering multiple ocular implants |
| US8808372B2 (en) * | 2012-04-27 | 2014-08-19 | Cold Winter Solutions, L.L.C. | Breast implant spacers for the treatment of periprosthetic breast implant infections |
| EP2872083A1 (en) | 2012-07-13 | 2015-05-20 | Bausch & Lomb Incorporated | Posterior capsulotomy using laser techniques |
| EP2951635A4 (en) * | 2013-01-30 | 2016-10-05 | Onefocus Technology Llc | METHOD FOR PRODUCING A CONFIDENT SOFT CONTACT LENS |
| US9592151B2 (en) | 2013-03-15 | 2017-03-14 | Glaukos Corporation | Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye |
| US11109957B2 (en) | 2014-09-22 | 2021-09-07 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US11938018B2 (en) | 2014-09-22 | 2024-03-26 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders |
| US10945832B2 (en) | 2014-09-22 | 2021-03-16 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US10299910B2 (en) | 2014-09-22 | 2019-05-28 | Kevin J. Cady | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| US10159562B2 (en) | 2014-09-22 | 2018-12-25 | Kevin J. Cady | Intraocular pseudophakic contact lenses and related systems and methods |
| US12447007B2 (en) | 2014-09-22 | 2025-10-21 | Onpoint Vision, Inc. | Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method |
| WO2016132185A1 (en) * | 2015-02-16 | 2016-08-25 | Prakhyat ROOP | Optical implantable member |
| US11116625B2 (en) | 2017-09-28 | 2021-09-14 | Glaukos Corporation | Apparatus and method for controlling placement of intraocular implants |
| WO2019070385A2 (en) | 2017-10-06 | 2019-04-11 | Glaukos Corporation | SYSTEMS AND METHODS FOR PLACING MULTIPLE OCULAR IMPLANTS |
| USD846738S1 (en) | 2017-10-27 | 2019-04-23 | Glaukos Corporation | Implant delivery apparatus |
| CN110541061B (zh) * | 2019-02-27 | 2021-04-27 | 中国宁波国际合作有限责任公司 | 活塞加工方法及旋转式压缩机加工方法 |
| CN110575289B (zh) * | 2019-09-20 | 2021-10-22 | 中国人民解放军陆军军医大学第一附属医院 | 一种骨缺损假体3d打印方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238281A (en) * | 1962-03-15 | 1966-03-01 | Kato Kiyosi | Production of molded wooden articles of any desired shape and three dimensions from the aggregated wood fibers |
| US4702244A (en) * | 1982-02-05 | 1987-10-27 | Staar Surgical Company | Surgical device for implantation of a deformable intraocular lens |
| US4573998A (en) * | 1982-02-05 | 1986-03-04 | Staar Surgical Co. | Methods for implantation of deformable intraocular lenses |
| CS269158B1 (en) * | 1988-04-01 | 1990-04-11 | Sulc Jiri | Hard intraocular eyeglass with elastic memory |
| JP3583801B2 (ja) * | 1993-03-03 | 2004-11-04 | ボストン サイエンティフィック リミテッド | 管腔用のステントおよび移植体 |
| US5492993A (en) * | 1994-02-03 | 1996-02-20 | Dow Corning Corporation | Strain-crystallizing poly(methyl(3,3,3-trifluoropropyl)-siloxane) elastomers and methods for making |
| AU1915595A (en) * | 1994-02-09 | 1995-08-29 | Kabi Pharmacia Ophthalmics, Inc. | Rapid implantation of shape transformable optical lenses |
-
1998
- 1998-02-13 US US09/023,391 patent/US6030416A/en not_active Expired - Lifetime
-
1999
- 1999-02-12 ES ES99908141T patent/ES2200502T3/es not_active Expired - Lifetime
- 1999-02-12 CN CNB998029351A patent/CN1226971C/zh not_active Expired - Fee Related
- 1999-02-12 AU AU27642/99A patent/AU748650B2/en not_active Ceased
- 1999-02-12 EP EP99908141A patent/EP1056415B1/en not_active Expired - Lifetime
- 1999-02-12 HU HU0100231A patent/HUP0100231A3/hu unknown
- 1999-02-12 CA CA002317746A patent/CA2317746C/en not_active Expired - Lifetime
- 1999-02-12 PL PL99342842A patent/PL342842A1/xx unknown
- 1999-02-12 KR KR1020007008881A patent/KR20010052169A/ko not_active Ceased
- 1999-02-12 SK SK1128-2000A patent/SK11282000A3/sk unknown
- 1999-02-12 IL IL13780799A patent/IL137807A/xx unknown
- 1999-02-12 DK DK99908141T patent/DK1056415T3/da active
- 1999-02-12 AT AT99908141T patent/ATE241328T1/de not_active IP Right Cessation
- 1999-02-12 RU RU2000123549/15A patent/RU2220681C2/ru not_active IP Right Cessation
- 1999-02-12 BR BR9907757-4A patent/BR9907757A/pt not_active IP Right Cessation
- 1999-02-12 JP JP2000531135A patent/JP2002502666A/ja active Pending
- 1999-02-12 NZ NZ505585A patent/NZ505585A/xx unknown
- 1999-02-12 DE DE69908307T patent/DE69908307T2/de not_active Expired - Lifetime
- 1999-02-12 PT PT99908141T patent/PT1056415E/pt unknown
- 1999-02-12 WO PCT/US1999/003090 patent/WO1999040877A1/en not_active Ceased
- 1999-02-12 TR TR2000/02259T patent/TR200002259T2/xx unknown
-
2000
- 2000-08-11 NO NO20004050A patent/NO318248B1/no unknown
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003534070A (ja) * | 2000-05-22 | 2003-11-18 | メデニアム インコーポレーテッド | 眼用装置のための結晶性ポリマー組成物 |
| JP2014525759A (ja) * | 2011-05-23 | 2014-10-02 | カリフォルニア インスティチュート オブ テクノロジー | 調節性眼内レンズ |
| WO2014027689A1 (ja) * | 2012-08-17 | 2014-02-20 | Hoya株式会社 | 眼内レンズ用部材及び眼内レンズ |
| JP2014036769A (ja) * | 2012-08-17 | 2014-02-27 | Hoya Corp | 眼内レンズ用部材及び眼内レンズ |
| JP2014036770A (ja) * | 2012-08-17 | 2014-02-27 | Hoya Corp | 眼内レンズ用部材及び眼内レンズ |
| JP2019118689A (ja) * | 2018-01-09 | 2019-07-22 | 株式会社ニデック | 眼内レンズ挿入器具および眼内レンズ挿入システム |
| JP7102735B2 (ja) | 2018-01-09 | 2022-07-20 | 株式会社ニデック | 眼内レンズ挿入器具および眼内レンズ挿入システム |
| US12295831B2 (en) | 2023-10-23 | 2025-05-13 | California Institute Of Technology | Liquid accommodating intraocular lens with an asymmetric chamber |
Also Published As
| Publication number | Publication date |
|---|---|
| PT1056415E (pt) | 2003-10-31 |
| PL342842A1 (en) | 2001-07-16 |
| AU748650B2 (en) | 2002-06-06 |
| WO1999040877A9 (en) | 1999-11-11 |
| WO1999040877A1 (en) | 1999-08-19 |
| KR20010052169A (ko) | 2001-06-25 |
| EP1056415A1 (en) | 2000-12-06 |
| EP1056415B1 (en) | 2003-05-28 |
| DK1056415T3 (da) | 2003-09-29 |
| NO20004050L (no) | 2000-10-12 |
| IL137807A0 (en) | 2001-10-31 |
| EP1056415A4 (en) | 2002-06-12 |
| DE69908307T2 (de) | 2004-04-29 |
| NO318248B1 (no) | 2005-02-21 |
| TR200002259T2 (tr) | 2001-05-21 |
| US6030416A (en) | 2000-02-29 |
| DE69908307D1 (de) | 2003-07-03 |
| IL137807A (en) | 2005-05-17 |
| NZ505585A (en) | 2002-11-26 |
| CN1226971C (zh) | 2005-11-16 |
| RU2220681C2 (ru) | 2004-01-10 |
| CA2317746C (en) | 2008-05-06 |
| ATE241328T1 (de) | 2003-06-15 |
| CN1305358A (zh) | 2001-07-25 |
| HUP0100231A2 (hu) | 2001-05-28 |
| ES2200502T3 (es) | 2004-03-01 |
| SK11282000A3 (sk) | 2001-02-12 |
| BR9907757A (pt) | 2000-11-14 |
| CA2317746A1 (en) | 1999-08-19 |
| HUP0100231A3 (en) | 2004-12-28 |
| AU2764299A (en) | 1999-08-30 |
| NO20004050D0 (no) | 2000-08-11 |
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