JP2002500893A5 - - Google Patents
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- Publication number
- JP2002500893A5 JP2002500893A5 JP2000528711A JP2000528711A JP2002500893A5 JP 2002500893 A5 JP2002500893 A5 JP 2002500893A5 JP 2000528711 A JP2000528711 A JP 2000528711A JP 2000528711 A JP2000528711 A JP 2000528711A JP 2002500893 A5 JP2002500893 A5 JP 2002500893A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- oligonucleotide
- seq
- set forth
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108091034117 Oligonucleotide Proteins 0.000 description 19
- 239000002773 nucleotide Substances 0.000 description 13
- 125000003729 nucleotide group Chemical group 0.000 description 13
- 238000000034 method Methods 0.000 description 11
- 230000003321 amplification Effects 0.000 description 9
- 238000003199 nucleic acid amplification method Methods 0.000 description 9
- 150000007523 nucleic acids Chemical class 0.000 description 9
- 108020004999 messenger RNA Proteins 0.000 description 8
- 239000000523 sample Substances 0.000 description 8
- 108010049977 Peptide Elongation Factor Tu Proteins 0.000 description 7
- 230000000295 complement effect Effects 0.000 description 7
- 238000001514 detection method Methods 0.000 description 6
- 108020004707 nucleic acids Proteins 0.000 description 5
- 102000039446 nucleic acids Human genes 0.000 description 5
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000186362 Mycobacterium leprae Species 0.000 description 4
- 108091028043 Nucleic acid sequence Proteins 0.000 description 4
- 102000008153 Peptide Elongation Factor Tu Human genes 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 230000035899 viability Effects 0.000 description 4
- 201000008827 tuberculosis Diseases 0.000 description 3
- 238000003556 assay Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000009396 hybridization Methods 0.000 description 2
- 238000013518 transcription Methods 0.000 description 2
- 230000035897 transcription Effects 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 description 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 description 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 1
- 101710137500 T7 RNA polymerase Proteins 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 241000894007 species Species 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98200184 | 1998-01-23 | ||
| EP98200184.4 | 1998-01-23 | ||
| PCT/EP1999/000323 WO1999037804A2 (en) | 1998-01-23 | 1999-01-19 | EF-Tu mRNA AS A MARKER FOR VIABILITY OF BACTERIA |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010226408A Division JP2011050387A (ja) | 1998-01-23 | 2010-10-06 | バクテリアの生存率に関するマーカーとしてのＥＦ−ＴｕｍＲＮＡ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002500893A JP2002500893A (ja) | 2002-01-15 |
| JP2002500893A5 true JP2002500893A5 (https=) | 2006-03-02 |
| JP4634604B2 JP4634604B2 (ja) | 2011-02-16 |
Family
ID=8233311
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000528711A Expired - Lifetime JP4634604B2 (ja) | 1998-01-23 | 1999-01-19 | バクテリアの生存率に関するマーカーとしてのＥＦ−ＴｕｍＲＮＡ |
| JP2010226408A Pending JP2011050387A (ja) | 1998-01-23 | 2010-10-06 | バクテリアの生存率に関するマーカーとしてのＥＦ−ＴｕｍＲＮＡ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010226408A Pending JP2011050387A (ja) | 1998-01-23 | 2010-10-06 | バクテリアの生存率に関するマーカーとしてのＥＦ−ＴｕｍＲＮＡ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6489110B1 (https=) |
| EP (1) | EP1049809B1 (https=) |
| JP (2) | JP4634604B2 (https=) |
| AT (1) | ATE343642T1 (https=) |
| AU (1) | AU2717699A (https=) |
| CA (1) | CA2318726C (https=) |
| DE (1) | DE69933755T2 (https=) |
| ES (1) | ES2275336T3 (https=) |
| WO (1) | WO1999037804A2 (https=) |
| ZA (1) | ZA99362B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1246935B1 (en) * | 1999-09-28 | 2013-08-14 | Geneohm Sciences Canada Inc. | Highly conserved genes and their use to generate probes and primers for detection of microorganisms |
| EP1950313A3 (en) * | 2000-03-27 | 2010-12-08 | GlaxoSmithKline LLC | Detection of viable agents |
| JPWO2002052034A1 (ja) * | 2000-12-26 | 2004-04-30 | 大島 譲二 | 生死判別方法及び核酸増幅方法 |
| JP2004534016A (ja) * | 2001-04-30 | 2004-11-11 | ノヴォロギックス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗菌剤 |
| EP1529117A2 (en) * | 2002-08-08 | 2005-05-11 | University of Lausanne | Method for the rapid assessment of the presence and viability of bacterial cells and use thereof |
| GB0324650D0 (en) * | 2003-10-22 | 2003-11-26 | Acolyte Biomedica Ltd | Using nucleic acids for clinical microbiology testing |
| US7309589B2 (en) * | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| AU2006274507B2 (en) * | 2005-07-27 | 2013-08-29 | Diagnostic Array Systems Pty Ltd | Method for the detection and/or identification of a microorganism |
| JP5138590B2 (ja) * | 2005-07-27 | 2013-02-06 | ディアグノスティック アレイ システムズ ピーティーワイ エルティーディー | 微生物の検出及び／又は同定方法 |
| JP5593037B2 (ja) * | 2009-03-12 | 2014-09-17 | 東洋水産株式会社 | 細菌測定用プライマーおよび細菌測定方法 |
| US11441167B2 (en) | 2019-11-20 | 2022-09-13 | Roche Molecular Systems, Inc. | Compositions and methods for rapid identification and phenotypic antimicrobial susceptibility testing of bacteria and fungi |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL71715A0 (en) | 1983-08-05 | 1984-09-30 | Miles Lab | Method,gene probes and test kit for detecting bacteria by nucleic acid hybridization |
| US5130238A (en) * | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| KR100399715B1 (ko) * | 1994-08-18 | 2003-12-18 | 악조 노벨 엔.브이. | Cmv핵산증폭 및 검출용 프라이머와 프로브 |
| US5994066A (en) | 1995-09-11 | 1999-11-30 | Infectio Diagnostic, Inc. | Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories |
| JPH09248186A (ja) * | 1996-03-15 | 1997-09-22 | Oozeki Kk | ラクトバチルス属微生物のポリペプチド鎖延長因子遺伝子Ｔｕおよびその利用 |
| US6444444B1 (en) * | 1996-07-10 | 2002-09-03 | Aventis Pasteur Limited | Genes encoding mycobacterial proteins associated with cell binding and cell entry and uses thereof |
| FR2755145B1 (fr) * | 1996-10-28 | 1999-01-15 | Gervais Danone Co | Procede de mise en evidence de contaminants microbiologiques vivants dans un echantillon de produit a usage alimentaire |
-
1999
- 1999-01-19 US US09/600,770 patent/US6489110B1/en not_active Expired - Lifetime
- 1999-01-19 AT AT99907386T patent/ATE343642T1/de not_active IP Right Cessation
- 1999-01-19 ES ES99907386T patent/ES2275336T3/es not_active Expired - Lifetime
- 1999-01-19 CA CA002318726A patent/CA2318726C/en not_active Expired - Lifetime
- 1999-01-19 WO PCT/EP1999/000323 patent/WO1999037804A2/en not_active Ceased
- 1999-01-19 JP JP2000528711A patent/JP4634604B2/ja not_active Expired - Lifetime
- 1999-01-19 DE DE69933755T patent/DE69933755T2/de not_active Expired - Lifetime
- 1999-01-19 EP EP99907386A patent/EP1049809B1/en not_active Expired - Lifetime
- 1999-01-19 AU AU27176/99A patent/AU2717699A/en not_active Abandoned
- 1999-01-19 ZA ZA9900362A patent/ZA99362B/xx unknown
-
2010
- 2010-10-06 JP JP2010226408A patent/JP2011050387A/ja active Pending
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