JP2002500650A5 - - Google Patents

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Publication number
JP2002500650A5
JP2002500650A5 JP1998550618A JP55061898A JP2002500650A5 JP 2002500650 A5 JP2002500650 A5 JP 2002500650A5 JP 1998550618 A JP1998550618 A JP 1998550618A JP 55061898 A JP55061898 A JP 55061898A JP 2002500650 A5 JP2002500650 A5 JP 2002500650A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1998550618A
Other languages
English (en)
Japanese (ja)
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JP2002500650A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1998/010376 external-priority patent/WO1998052559A1/en
Publication of JP2002500650A publication Critical patent/JP2002500650A/ja
Publication of JP2002500650A5 publication Critical patent/JP2002500650A5/ja
Pending legal-status Critical Current

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JP55061898A 1997-05-23 1998-05-21 Rafキナーゼ阻害剤 Pending JP2002500650A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12642097P 1997-05-23 1997-05-23
US86302197A 1997-05-23 1997-05-23
US08/863,021 1997-05-23
PCT/US1998/010376 WO1998052559A1 (en) 1997-05-23 1998-05-21 Raf kinase inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009251583A Division JP5260474B2 (ja) 1997-05-23 2009-11-02 Rafキナーゼ阻害剤

Publications (2)

Publication Number Publication Date
JP2002500650A JP2002500650A (ja) 2002-01-08
JP2002500650A5 true JP2002500650A5 (enExample) 2005-12-08

Family

ID=26824631

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55061898A Pending JP2002500650A (ja) 1997-05-23 1998-05-21 Rafキナーゼ阻害剤

Country Status (10)

Country Link
EP (1) EP0986382B1 (enExample)
JP (1) JP2002500650A (enExample)
AT (1) ATE399007T1 (enExample)
AU (1) AU7585598A (enExample)
CA (1) CA2291065C (enExample)
DE (2) DE986382T1 (enExample)
DK (1) DK0986382T3 (enExample)
ES (1) ES2153337T3 (enExample)
GR (1) GR20010300033T1 (enExample)
WO (1) WO1998052559A1 (enExample)

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ATE538794T1 (de) 1999-01-13 2012-01-15 Bayer Healthcare Llc Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
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US7351834B1 (en) 1999-01-13 2008-04-01 Bayer Pharmaceuticals Corporation ω-Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
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JP2004531571A (ja) 2001-05-25 2004-10-14 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド サイトカイン生産のインヒビターとしてのカルバメート及びオキサミド化合物
PL395097A1 (pl) * 2001-06-11 2011-10-10 Vertex Pharmaceuticals (Canada) Incorporated Sposób wytwarzania związku o wzorze A stanowiącego pochodną tiofenu
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ATE529406T1 (de) 2002-02-11 2011-11-15 Bayer Healthcare Llc Aryl-harnstoffe als kinase inhibitoren
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DE60310730T2 (de) 2002-07-09 2007-05-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische zusammensetzungen aus anticholinergica und p38 kinase hemmern zur behandlung von erkrankungen der atemwege
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CN104688697A (zh) 2005-03-07 2015-06-10 拜尔健康护理有限责任公司 用于治疗癌症的包含ω-羧芳基取代的二苯基脲的药物组合物
EP2546246A3 (en) 2005-05-13 2013-04-24 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of flavivirus infections
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JP5072595B2 (ja) 2005-08-05 2012-11-14 中外製薬株式会社 マルチキナーゼ阻害剤
US7825120B2 (en) 2005-12-15 2010-11-02 Cytokinetics, Inc. Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
TW200808321A (en) 2005-12-15 2008-02-16 Cytokinetics Inc Certain chemical entities, compositions and methods
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EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
CN102627657B (zh) * 2012-03-09 2015-01-07 苏州施亚生物科技有限公司 3-(4-甲氧基-苄基)-1h-嘧啶-2,4-二酮衍生物的合成方法
WO2015041534A1 (en) 2013-09-20 2015-03-26 Stichting Het Nederlands Kanker Instituut P90rsk in combination with raf/erk/mek
EP3046557A1 (en) 2013-09-20 2016-07-27 Stichting Het Nederlands Kanker Instituut Rock in combination with mapk-pathway
US20170027940A1 (en) 2014-04-10 2017-02-02 Stichting Het Nederlands Kanker Instituut Method for treating cancer
CN106470974B (zh) 2014-04-17 2019-07-16 韩国巴斯德研究所 用于治疗病毒感染的化合物
WO2015178770A1 (en) 2014-05-19 2015-11-26 Stichting Het Nederlands Kanker Instituut Compositions for cancer treatment
HUE053286T2 (hu) * 2016-10-26 2021-06-28 Ishihara Sangyo Kaisha Eljárás 3-metil-2-tiofénkarbonsav elõállítására

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JPS61268678A (ja) * 1985-05-17 1986-11-28 バイエル・アクチエンゲゼルシヤフト 生産増進剤
US5597719A (en) * 1994-07-14 1997-01-28 Onyx Pharmaceuticals, Inc. Interaction of RAF-1 and 14-3-3 proteins
US5773459A (en) * 1995-06-07 1998-06-30 Sugen, Inc. Urea- and thiourea-type compounds
DE1019040T1 (de) * 1997-05-23 2001-02-08 Bayer Corp., West Haven Hemmung von p38 kinase aktivität durch arylharnstoff

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