JP2002294113A - Ink for detecting ethylene oxide gas sterilization - Google Patents
Ink for detecting ethylene oxide gas sterilizationInfo
- Publication number
- JP2002294113A JP2002294113A JP2001101274A JP2001101274A JP2002294113A JP 2002294113 A JP2002294113 A JP 2002294113A JP 2001101274 A JP2001101274 A JP 2001101274A JP 2001101274 A JP2001101274 A JP 2001101274A JP 2002294113 A JP2002294113 A JP 2002294113A
- Authority
- JP
- Japan
- Prior art keywords
- ink
- ethylene oxide
- oxide gas
- weight
- sterilization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、エチレンオキサイ
ドガス滅菌における滅菌処理検知用の印刷インキの改良
に関し、特に高圧蒸気滅菌処理された場合において他へ
の汚染（色移り）がないエチレンオキサイドガス滅菌検
知用インキ及びそのインキを用いたインジケーターに関
する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an improvement in a printing ink for detecting sterilization in ethylene oxide gas sterilization, and more particularly to an ethylene oxide gas sterilization free from contamination (color transfer) when subjected to high-pressure steam sterilization. The present invention relates to a detection ink and an indicator using the ink.
【０００２】[0002]
【従来の技術】従来、医療用のガーゼ、包帯、脱脂綿等
の材料あるいは、メス、ハサミ、注射器等の器具は一般
に、それらのメーカーで予め滅菌されて病院等に納入さ
れている。また、これらの医療用材料あるいは器具のう
ちで使い捨てでなく繰り返し使用できる種類のものに関
しては、使用した後、病院内の中央材料室で洗浄および
滅菌されて再使用に供される。これらの滅菌方法として
はエチレンオキサイドガス滅菌法や高圧蒸気滅菌法が多
く用いられている。ところで、医療用材料あるいは器具
を滅菌する場合には、滅菌後、使用時まで無菌保存する
必要から、それらを個々に予め紙、布、不織布あるいは
プラスチックフィルムなどから成る袋やその他の包装材
料で包装し、包装のまま滅菌処理することが行われる。
これらの滅菌処理される医療用材料あるいは器具の包装
物の外部の目立つ箇所に、滅菌処理前と処理後とで色相
が変化する滅菌インジケーターインキを印刷するか、あ
るいは該インジケーターインキを予め印刷してある粘着
ラベル、粘着テープなどを貼着しておくことによって、
滅菌処理済みの医療用材料あるいは器具の包装物と未処
理のそれらとが混同されることを防止できるようにして
いる。ここで、該包装物に滅菌インジケーターインキを
印刷する場合、エチレンオキサイドガス滅菌用インジケ
ーターインキと高圧蒸気滅菌インジケーターインキの両
方を印刷し、どちらの滅菌方法が行われても滅菌処理の
有無を検知できるようにされていることが多い。従来、
エチレンオキサイドガス滅菌用インジケーターインキと
しては、特公昭５２−１００４３号公報に記載されるも
のが知られている。2. Description of the Related Art Conventionally, medical materials such as gauze, bandages, absorbent cotton, and instruments such as scalpels, scissors, and syringes are generally sterilized in advance by such manufacturers and delivered to hospitals and the like. Further, among these medical materials or instruments, those which can be used repeatedly rather than disposable, are used, then washed and sterilized in a central material room in a hospital, and then reused. As these sterilization methods, ethylene oxide gas sterilization and high-pressure steam sterilization are often used. By the way, when sterilizing medical materials or instruments, it is necessary to aseptically store them after sterilization until use, so they are individually packaged in advance in bags made of paper, cloth, nonwoven fabric, plastic film, etc., or other packaging materials. Then, sterilization treatment is performed on the package as it is.
A sterile indicator ink whose hue changes before and after sterilization is printed on a prominent place outside the package of medical materials or instruments to be sterilized, or the indicator ink is printed in advance. By attaching a certain adhesive label, adhesive tape, etc.,
It is possible to prevent confusion between the sterilized medical material or the package of the device and the unprocessed package. Here, when the sterilization indicator ink is printed on the package, both the indicator ink for ethylene oxide gas sterilization and the high-pressure steam sterilization indicator ink are printed, so that the presence or absence of the sterilization process can be detected regardless of which sterilization method is performed. That is often the case. Conventionally,
As an indicator ink for ethylene oxide gas sterilization, those described in JP-B-52-10043 are known.
【０００３】[0003]
【発明が解決しようとする課題】しかし、特公昭５２−
１００４３号公報に記載されているエチレンオキサイド
ガス滅菌用インジケーターインキでは、上述したような
医療用材料あるいは器具の包装物にエチレンオキサイド
ガス滅菌用インジケーターインキと高圧蒸気滅菌用イン
ジケーターインキの両方を印刷し、該包装物を高圧蒸気
滅菌処理した場合、他の包装物等の被滅菌材料又は包装
物の滅菌インキが印刷されていないところに色移りし汚
染されるという問題がある。[Problems to be solved by the invention]
In the indicator ink for ethylene oxide gas sterilization described in Japanese Patent No. 10043, both the indicator ink for ethylene oxide gas sterilization and the indicator ink for high-pressure steam sterilization are printed on a medical material or a package of a device as described above, When the package is subjected to high-pressure steam sterilization, there is a problem that the material to be sterilized, such as another package, or the sterile ink of the package is discolored and contaminated.
【０００４】本発明の目的は、高圧蒸気滅菌処理された
場合でも、他の被滅菌材料に汚染（色移り）しないエチ
レンオキサイドガス滅菌検知用インキ及びインジケータ
ーを提供するところにある。[0004] It is an object of the present invention to provide an ink and an indicator for detecting ethylene oxide gas sterilization which do not contaminate (color transfer) other materials to be sterilized even when subjected to high-pressure steam sterilization.
【０００５】[0005]
【課題を解決するための手段】上記目的を達成するため
鋭意検討した結果、本発明は、必須成分として、下記一
般式（１）で示されるアゾ染料のうち、堅ロウ度の昇華
試験（ＪＩＳ Ｌ ０８５４−１９６７）での評価が５
以上のアゾ染料を含んでなるインキ組成物が好ましい事
を見出した。一般式（１）Means for Solving the Problems As a result of intensive studies to achieve the above-mentioned object, the present invention shows that, as an essential component, among the azo dyes represented by the following general formula (1), a sublimation test (JIS) L 0854-1967) is 5
It has been found that an ink composition containing the above azo dye is preferable. General formula (1)
【化２】 ［式中、Ａはエチレン残基又はＯ−フェニレン残基を表
わし、ＢはＰ−位にカップリングすることができるアニ
リン誘導体残基又はエナミン残基を表わす。］Embedded image [Wherein, A represents an ethylene residue or an O-phenylene residue, and B represents an aniline derivative residue or an enamine residue that can be coupled to the P-position. ]
【０００６】また、上記エチレンオキサイド滅菌検知用
インキを用いたエチレンオキサイドガス滅菌検知インジ
ケーターとして好ましい事を見出した。It has also been found that the above-mentioned ethylene oxide sterilization detecting ink is preferable as an ethylene oxide gas sterilization detection indicator.
【０００７】[0007]
【発明の実施の形態】上記一般式（１）で示されるアゾ
染料は、例えば特公昭５２−１００４３号公報に記載さ
れており、公知の染料であるが、本発明者は、該染料の
うち、堅ロウ度の昇華試験（ＪＩＳ Ｌ ０８５４−１
９６７）での評価が５以上のアゾ染料を含む印刷インキ
組成物が、エチレンオキサイドガス滅菌におけるインジ
ケーターとしての色相変化、色濃度等において、すぐれ
た性能を示すことはもちろんのこと、更に高圧蒸気滅菌
処理された場合でもすぐれた耐汚染性を示すことを見出
した。DESCRIPTION OF THE PREFERRED EMBODIMENTS The azo dye represented by the above general formula (1) is described in, for example, Japanese Patent Publication No. 52-10043, and is a known dye. And sublimation test of stiffness (JIS L 0854-1)
The printing ink composition containing an azo dye having an evaluation of 967) of 5 or more shows excellent performance in hue change and color density as an indicator in ethylene oxide gas sterilization, and furthermore, high-pressure steam sterilization. It has been found that even when treated, it shows excellent stain resistance.
【０００８】本発明で用いるアゾ染料としては、例え
ば、C.I.Disperse Red 58やC.I.Disperse Red 88等をあ
げることができる。これらアゾ染料の中でも、特にC.I.
Disperse Red 58 が、エチレンオキサイドガス滅菌イン
ジケーターとしての色相変化や色濃度等の観点から好ま
しい。Examples of the azo dye used in the present invention include CI Disperse Red 58 and CI Disperse Red 88. Among these azo dyes, especially CI
Disperse Red 58 is preferred from the viewpoint of hue change and color density as an ethylene oxide gas sterilization indicator.
【０００９】本発明の目的に使用するインキ組成物は、
上記アゾ染料が含有されている限り使用することができ
るが、溶剤、樹脂、添加剤等公知の印刷インキ組成物に
用いられている成分を適宜配合することができる。ま
た、エチレンオキサイドガスと容易に反応できる様にす
るために、触媒の添加が好ましい。The ink composition used for the purpose of the present invention comprises:
As long as the above-mentioned azo dye is contained, it can be used, but components used in known printing ink compositions such as a solvent, a resin, and an additive can be appropriately compounded. In order to easily react with the ethylene oxide gas, it is preferable to add a catalyst.
【００１０】溶剤としては、通常、印刷用のインキ組成
物に用いられる溶剤であればいずれも使用できる。例え
ば、アルコール系、エステル系、エーテル系、ケトン
系、炭化水素系等の各種溶剤が使用でき、使用する染
料、樹脂の溶解性等に応じて適宜選択すれば良い。As the solvent, any solvent can be used, so long as it is generally used for an ink composition for printing. For example, various solvents such as alcohols, esters, ethers, ketones, and hydrocarbons can be used, and they may be appropriately selected according to the dyes used, the solubility of the resin, and the like.
【００１１】樹脂としては、印刷用のインキ組成物に用
いられている公知の樹脂成分を使用できるが、特にロジ
ン変性マレイン酸樹脂、ニトロセルロース、エチルセル
ロースが色濃度の面で好ましい。As the resin, known resin components used in printing ink compositions can be used, and rosin-modified maleic resin, nitrocellulose and ethylcellulose are particularly preferable in terms of color density.
【００１２】添加剤としては、染料の溶解性を良くする
ことができれば、特に制限されず、例えば1,3-Dimethyl
-2-Imidazolidinone等が挙げられる。これら添加剤を添
加することにより、主として色濃度を向上させることが
できる。The additive is not particularly limited as long as it can improve the solubility of the dye. For example, 1,3-dimethyl
-2-Imidazolidinone and the like. By adding these additives, the color density can be mainly improved.
【００１３】触媒としては、有機酸が良好であるが、特
にマロン酸、マレイン酸が、エチレンオキサイドガス滅
菌におけるインジケーターとして、その色相変化の面で
好ましい。As a catalyst, an organic acid is preferable, but malonic acid and maleic acid are particularly preferable as an indicator in ethylene oxide gas sterilization in view of color change.
【００１４】これらをすべて配合する場合の割合は、用
いる一般式（１）で示されるアゾ染料の種類、用途等に
応じて適宜設定すれば良いが、通常は本発明インキ中ア
ゾ染料１〜１０重量％（好ましくは３〜７％）、溶剤４
０〜９０重量％（好ましくは６０〜８０重量％）、樹脂
５０重量％以下（好ましくは１０〜３０重量％）、添加
剤０．１〜１０重量％（好ましくは０．５％〜５重量
％）、触媒０．１〜１０重量％（好ましくは０．５〜５
重量％）等で調整すれば良い。The proportion when all of these are blended may be appropriately set according to the kind, use, etc. of the azo dye represented by the general formula (1) to be used. % (Preferably 3-7%), solvent 4
0 to 90% by weight (preferably 60 to 80% by weight), resin 50% by weight or less (preferably 10 to 30% by weight), additive 0.1 to 10% by weight (preferably 0.5 to 5% by weight) ), Catalyst 0.1 to 10% by weight (preferably 0.5 to 5)
Weight%) or the like.
【００１５】これら各成分は、同時に又は順次に配合
し、デゾルバー等の公知の撹拌機を用いて均一に混合す
れば良い。例えば、まず溶剤に有機酸、樹脂、アゾ染
料、添加剤等を順に配合し、混合・撹拌すれば良い。These components may be simultaneously or sequentially compounded and uniformly mixed using a known stirrer such as a dissolver. For example, first, an organic acid, a resin, an azo dye, an additive, and the like may be mixed in a solvent in order, and then mixed and stirred.
【００１６】以上の様な工程でインキ化できるが、印刷
条件に適する様に溶剤の選択添加、その他の補助剤も加
えて最終インキとする。出来上がったインキはグラビア
印刷、フレキソ印刷に適したものである。Although the ink can be formed by the above-described steps, a final ink is obtained by selectively adding a solvent and adding other auxiliaries so as to be suitable for printing conditions. The resulting ink is suitable for gravure and flexographic printing.
【００１７】本発明はエチレンオキサイドガスと変色せ
ず、かつ堅ロウ度の昇華試験（ＪＩＳ Ｌ ０８５４−
１９６７）での評価が５以上の他の染料、顔料を併用す
る事によって、所望の色相変化を作る事ができる。The present invention provides a sublimation test (JIS L 0854) which does not discolor with ethylene oxide gas and has a firm waxiness.
A desired change in hue can be produced by using other dyes and pigments having an evaluation of 1967) of 5 or more in combination.
【００１８】[0018]
【実施例】以下、実施例を示し、本発明の特徴をより一
層明確にする。The following examples are provided to further clarify the features of the present invention.
【００１９】（実施例１）アゾ染料（C.I.Disperse Red
58）１重量部、溶剤としてエタノール７０重量部、ト
ルエン５重量部、樹脂としてロジン変性マレイン酸樹脂
（「テスポール１１５８」日立化成社製）１８重量部、
エチルセルロース（「エトセル１０」ダウケミカル社
製）５重量部、触媒としてマレイン酸１重量部を均一に
撹拌機により混合し、本発明インキを調製した。(Example 1) Azo dye (CIDisperse Red)
58) 1 part by weight, 70 parts by weight of ethanol as a solvent, 5 parts by weight of toluene, 18 parts by weight of a rosin-modified maleic resin ("Tespol 1158" manufactured by Hitachi Chemical Co., Ltd.) as a resin,
5 parts by weight of ethyl cellulose (“Ethocel 10” manufactured by Dow Chemical Company) and 1 part by weight of maleic acid as a catalyst were uniformly mixed with a stirrer to prepare an ink of the present invention.
【００２０】（実施例２）アゾ染料（C.I.Disperse Red
88）１重量部、溶剤としてエタノール６５重量部、酢
酸エチル１０重量部、樹脂としてロジン変性マレイン酸
樹脂（「マルキードＮｏ．３４」荒川化学社製）１８重
量部、エチルセルロース（「エトセル１０」ダウケミカ
ル社製）５重量部、触媒としてマロン酸１重量部を均一
に撹拌機により混合し、本発明インキを調製した。Example 2 Azo dye (CIDisperse Red)
88) 1 part by weight, 65 parts by weight of ethanol as solvent, 10 parts by weight of ethyl acetate, 18 parts by weight of rosin-modified maleic resin (“Marquid No. 34” manufactured by Arakawa Chemical Co., Ltd.), and ethyl cellulose (“Ethocel 10” Dow Chemical) 5 parts by weight (manufactured by the company) and 1 part by weight of malonic acid as a catalyst were uniformly mixed with a stirrer to prepare an ink of the present invention.
【００２１】（実施例３）アゾ染料（C.I.Disperse Red
58）１重量部、溶剤としてイソプロピルアルコール６
０重量部、プロピレングリコールモノメチルエーテル
（「ダウアノールＰＭ」ダウケミカル社製）１０重量
部、樹脂としてフェノール樹脂（「タマノル１００Ｓ」
荒川化学社製）１８重量部、ニトロセルロース（「工業
用硝化綿ＦＱＲＳ１／８」ダイセル化学社製）１０重量
部、触媒として５，５´−チオジサリチル酸１重量部を
均一に撹拌機により混合し、本発明インキを調製した。Example 3 Azo dye (CIDisperse Red)
58) 1 part by weight, isopropyl alcohol 6 as solvent
0 parts by weight, 10 parts by weight of propylene glycol monomethyl ether (“Dowanol PM” manufactured by Dow Chemical Company), and a phenol resin (“Tamanol 100S”) as a resin
18 parts by weight of Arakawa Chemical Co., Ltd., 10 parts by weight of nitrocellulose ("Industrial Nitrified Cotton FQRS1 / 8" manufactured by Daicel Chemical Co., Ltd.), and 1 part by weight of 5,5'-thiodisalicylic acid as a catalyst are uniformly mixed with a stirrer. Then, the ink of the present invention was prepared.
【００２２】（実施例４）アゾ染料（C.I.Disperse Red
88）１重量部、溶剤としてイソプロピルアルコール６
０重量部、プロピレングリコールモノメチルエーテル
（「ダウアノールＰＭ」ダウケミカル社製）１０重量
部、樹脂としてロジン変性マレイン酸樹脂（「テスポー
ル１１５８」日立化成社製）１８重量部、ニトロセルロ
ース（「工業用硝化綿ＦＱＲＳ１／８」ダイセル化学社
製）１０重量部、触媒としてＰ−トルエンスルホン酸１
重量部を均一に撹拌機により混合し、本発明インキを調
製した。Example 4 Azo dye (CIDisperse Red)
88) 1 part by weight, isopropyl alcohol 6 as solvent
0 parts by weight, 10 parts by weight of propylene glycol monomethyl ether ("Dowanol PM" manufactured by Dow Chemical Company), 18 parts by weight of a rosin-modified maleic resin ("Tespol 1158" manufactured by Hitachi Chemical Co., Ltd.), and nitrocellulose ("Industrial Nitrification") Cotton FQRS1 / 8 "manufactured by Daicel Chemical Co., Ltd.) 10 parts by weight, P-toluenesulfonic acid 1 as a catalyst
The parts by weight were uniformly mixed with a stirrer to prepare an ink of the present invention.
【００２３】（試験例）実施例１〜４で得られたインキ
におけるエチレンオキサイドガス滅菌での変色性、及び
高圧蒸気滅菌処理での汚染性（色移り）を調べた。(Test Example) The inks obtained in Examples 1 to 4 were examined for discoloration by ethylene oxide gas sterilization and contamination (color transfer) by high-pressure steam sterilization.
【００２４】実施例１〜４で得られたインキ１００重量
部に対し、エタノール３０重量部を加えて希釈し、グラ
ビア印刷機にて滅菌紙上に印刷した。得られた印刷物を
エチレンオキサイドガス滅菌処理（エチレンオキサイド
２０重量％、炭酸ガス８０重量％の混合ガスを２ｋｇ／
ｃｍ2の圧で使用し、５０℃３時間滅菌処理）すると、
赤色から鮮明な青色に変色した。100 parts by weight of the inks obtained in Examples 1 to 4 were diluted by adding 30 parts by weight of ethanol and printed on sterilized paper by a gravure printing machine. The obtained printed matter is subjected to an ethylene oxide gas sterilization treatment (a mixed gas of ethylene oxide 20% by weight and carbon dioxide gas 80% by weight is mixed at 2 kg /
When used at a pressure of 2 cm2 and sterilized at 50 ° C for 3 hours)
The color changed from red to clear blue.
【００２５】上記で得られた印刷物を何も印刷されてい
ない滅菌紙に挟み、固定し、１２１℃２０分、１３４℃
２０分高圧蒸気滅菌すると、印刷物を挟んだ滅菌紙への
汚染はどちらの条件でも認められなかった。The printed matter obtained above is sandwiched between sterilized papers on which nothing is printed, fixed and fixed at 121 ° C. for 20 minutes and 134 ° C.
After high-pressure steam sterilization for 20 minutes, no contamination of the sterilized paper sandwiching the printed matter was observed under any of the conditions.
【００２６】[0026]
【発明の効果】本発明は、必須成分として、一般式
（１）で示されるアゾ染料のうち、堅ロウ度の昇華試験
（ＪＩＳ Ｌ ０８５４−１９６７）での評価が５以上
のアゾ染料を含んでなるエチレンオキサイドガス滅菌検
知用インキであるので、高圧蒸気滅菌にて他の被滅菌材
料が汚染（色移り）されることを防止することができ
る。また、汚染（色移り）のないエチレンオキサイドガ
ス滅菌検知インジケーターができる。According to the present invention, among the azo dyes represented by the general formula (1), the azo dyes having an evaluation of 5 or more in a sublimation test of stiffness (JIS L 0854-1967) are contained as essential components. Since it is an ethylene oxide gas sterilization detection ink composed of the following, contamination (color transfer) of another material to be sterilized by high-pressure steam sterilization can be prevented. In addition, an ethylene oxide gas sterilization detection indicator free of contamination (color transfer) can be obtained.
───────────────────────────────────────────────────── フロントページの続き Ｆターム(参考） 2G042 AA01 BD12 CA10 CB03 DA08 FA11 FB02 2G054 AB10 CA30 EA06 GB04 GE06 4J039 AB02 AB08 AD14 BC01 BC03 BC07 BC12 BC16 BC20 BC32 BC34 BC40 BC55 BE02 BE12 BE33 FA07 GA34 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 2G042 AA01 BD12 CA10 CB03 DA08 FA11 FB02 2G054 AB10 CA30 EA06 GB04 GE06 4J039 AB02 AB08 AD14 BC01 BC03 BC07 BC12 BC16 BC20 BC32 BC34 BC40 BC55 BE02 BE12 BE33 FA07 GA34
Claims (2)
堅ロウ度の昇華試験（ＪＩＳ Ｌ ０８５４−１９６
７）での評価が５以上のアゾ染料を必須成分としたエチ
レンオキサイドガス滅菌検知用インキ。 【化１】 ［式中、Ａはエチレン残基又はＯ−フェニレン残基を表
わし、ＢはＰ−位にカップリングすることができるアニ
リン誘導体残基又はエナミン残基を表わす。］1. An azo dye represented by the following general formula:
Sublimation test of rigidity (JIS L 0854-196)
Ink for ethylene oxide gas sterilization detection containing an azo dye having an evaluation of 7) of 5 or more as an essential component. Embedded image [Wherein, A represents an ethylene residue or an O-phenylene residue, and B represents an aniline derivative residue or an enamine residue that can be coupled to the P-position. ]
知用インキを用いたエチレンオキサイドガス滅菌検知イ
ンジケーター。2. An ethylene oxide gas sterilization detection indicator using the ethylene oxide sterilization detection ink according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001101274A JP2002294113A (en) | 2001-03-30 | 2001-03-30 | Ink for detecting ethylene oxide gas sterilization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001101274A JP2002294113A (en) | 2001-03-30 | 2001-03-30 | Ink for detecting ethylene oxide gas sterilization |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002294113A true JP2002294113A (en) | 2002-10-09 |
Family
ID=18954617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001101274A Withdrawn JP2002294113A (en) | 2001-03-30 | 2001-03-30 | Ink for detecting ethylene oxide gas sterilization |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2002294113A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007302816A (en) * | 2006-05-12 | 2007-11-22 | Nichiyu Giken Kogyo Co Ltd | Sterile indicator ink composition for offset printing or letterpress printing |
| EP2153853A1 (en) * | 2008-08-07 | 2010-02-17 | Nichiyu Giken Kogyo Co., Ltd. | Composition of indicator for detecting sterilization |
| US8222327B2 (en) | 2008-03-10 | 2012-07-17 | Hogy Medical Co., Ltd. | Plasma sterilization indicator |
| JP2012245215A (en) * | 2011-05-30 | 2012-12-13 | Nichiyu Giken Kogyo Co Ltd | Material for suppressing color fading or color transfer of sterilization indicator and bag for sterilization using the same |
| CN113429828A (en) * | 2021-06-22 | 2021-09-24 | 山东新华医疗器械股份有限公司 | Water-based environment-friendly ethylene oxide sterilization indicating ink and preparation method thereof |
-
2001
- 2001-03-30 JP JP2001101274A patent/JP2002294113A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007302816A (en) * | 2006-05-12 | 2007-11-22 | Nichiyu Giken Kogyo Co Ltd | Sterile indicator ink composition for offset printing or letterpress printing |
| US8222327B2 (en) | 2008-03-10 | 2012-07-17 | Hogy Medical Co., Ltd. | Plasma sterilization indicator |
| EP2153853A1 (en) * | 2008-08-07 | 2010-02-17 | Nichiyu Giken Kogyo Co., Ltd. | Composition of indicator for detecting sterilization |
| JP2012245215A (en) * | 2011-05-30 | 2012-12-13 | Nichiyu Giken Kogyo Co Ltd | Material for suppressing color fading or color transfer of sterilization indicator and bag for sterilization using the same |
| CN113429828A (en) * | 2021-06-22 | 2021-09-24 | 山东新华医疗器械股份有限公司 | Water-based environment-friendly ethylene oxide sterilization indicating ink and preparation method thereof |
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