CN111471346A - Peroxide sterilization water-based organic ink and preparation method and application thereof - Google Patents
Peroxide sterilization water-based organic ink and preparation method and application thereof Download PDFInfo
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- CN111471346A CN111471346A CN202010494250.0A CN202010494250A CN111471346A CN 111471346 A CN111471346 A CN 111471346A CN 202010494250 A CN202010494250 A CN 202010494250A CN 111471346 A CN111471346 A CN 111471346A
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/02—Printing inks
- C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/02—Printing inks
- C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
- C09D11/033—Printing inks characterised by features other than the chemical nature of the binder characterised by the solvent
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D11/00—Inks
- C09D11/50—Sympathetic, colour changing or similar inks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
Abstract
The invention provides peroxide sterilization water-based organic ink and a preparation method and application thereof, wherein the peroxide sterilization water-based organic ink is prepared from the following raw materials: 10-45 wt% of connecting material; 0.1 wt% -2 wt% of organic dye; 1 to 20 weight percent of alkaline control agent; 50 wt% -75 wt% of aqueous system solvent; the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol. Compared with the prior art, the peroxide sterilization water-based organic ink provided by the invention adopts a water-based system solvent, is matched with other components with specific contents, realizes better interaction, has the advantages of low VOCs (volatile organic compounds) emission, no heavy metal and avoidance of heavy metal pollution, and can be widely applied to printing of products such as indicator cards, indicator labels (adhesive tapes), paper plastic bags and the like, and the color of the products can be changed after the products are sterilized by peroxide, thereby playing an indicating role.
Description
Technical Field
The invention relates to the technical field of printing ink, in particular to peroxide sterilization water-based organic printing ink and a preparation method and application thereof.
Background
In the daily work of hospitals, various instruments and tools are often required to be disinfected and sterilized. With the continuous improvement of the awareness of people on health, the demand of various medical supplies is increasing, the products need to be strictly sterilized before use, and the sterilization process also relates to the fields of medical treatment, medicines, foods, sanitary supplies and the like. Therefore, higher demands are made on routine examination and rapid identification of the sterilization effect.
Peroxide sterilization is a sterilization mode for instruments which are used in hospitals and cannot resist high temperature and high humidity. According to the national sterilization standard of medical instruments, hospital medical care personnel are required to place a corresponding chemical indicator card for sterilization at the same time when the instruments are sterilized every time, observe the color change of the indicator card, and conveniently judge whether set sterilization parameters are reached by the medical care personnel, and package or pack the instruments by using corresponding labels, adhesive tapes, paper-plastic bags and other products; the indication card is used for a corresponding sterilization mode, so that medical personnel can conveniently judge whether sterilization parameters are met; the indicating label (adhesive tape) is used for corresponding sterilization modes, only judges whether the sterilization is carried out or not and belongs to sterilization process indicators; the paper plastic bag is used for wrapping sterilized articles and is provided with indication printing ink, so that a user can conveniently judge whether the sterilized articles are sterilized.
The currently used ink is organic ink, contains a large amount of organic solvent, can cause the discharge of VOCs with very high concentration, and is harmful to the health of production personnel. VOCs have complex components, special smell, permeability, volatilization, fat solubility and other characteristics, and can cause a plurality of uncomfortable symptoms of a human body; it also has toxic, irritant and teratogenic effects, especially benzene, toluene, xylene, formaldehyde are the most harmful to human health, and long-term exposure can cause anemia and leukemia; in addition, VOCs gas can also cause lesions in the respiratory, renal, pulmonary, hepatic, nervous, digestive and hematopoietic systems; with the increase of the concentration of VOCs, the human body can have symptoms of nausea, headache, convulsion, coma and the like.
With the increasing importance of the country on environmental protection, the development of solvent type printing ink is more and more limited, and the discharge and treatment of VOCs are limited; there is therefore a trend to develop corresponding aqueous inks. Meanwhile, as the ink is applied to medical sterilization products, the ink cannot contain heavy metals, particularly lead substances, and the existence of the heavy metals can pollute instruments and cause the risk of infection of patients in the operation process.
Disclosure of Invention
In view of the above, the invention aims to provide peroxide sterilization aqueous organic ink and a preparation method and application thereof, the peroxide sterilization aqueous organic ink provided by the invention changes in color after sterilization, so as to play an indicating role, has the advantages of low VOCs (volatile organic compounds) emission, no heavy metal and avoidance of heavy metal pollution, and can be widely applied to printing of products such as indicator cards, indicator labels (adhesive tapes), paper plastic bags and the like.
The invention provides peroxide sterilization water-based organic ink which is prepared from the following raw materials:
10-45 wt% of connecting material;
0.1 wt% -2 wt% of organic dye;
1 to 20 weight percent of alkaline control agent;
50 wt% -75 wt% of aqueous system solvent;
the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol.
Preferably, the binder is selected from one or more of acrylic resin, polyvinyl alcohol resin, polyurethane resin, alkyd resin and rosin resin.
Preferably, the organic dye is selected from one or more of indigo, basic blue, basic royal blue, basic brilliant blue and basic lake blue.
Preferably, the alkali control agent is selected from one or more of ammonia, ethanolamine, methylamine, ethylamine, propylamine, aniline, cyclohexylamine and tetrabutylammonium bromide.
Preferably, the mass ratio of water to the organic solvent in the aqueous system solvent is 3: (2-10).
The invention also provides a preparation method of the peroxide sterilization water-based organic ink, which comprises the following steps:
a) dissolving the binder in an aqueous system solvent, sequentially adding the organic dye and the alkali control agent, and mixing to obtain the peroxide sterilized aqueous organic ink.
Preferably, the mixing in step a) is performed by stirring; the stirring temperature is 15-35 ℃, the rotating speed is 10-50 r/min, and the time is 3-6 h.
The present invention also provides an indicator material for peroxide sterilization monitoring comprising:
a substrate;
a color-changeable ink layer compounded on the substrate;
a protective layer compounded on the color-changeable ink layer;
the color-changeable ink layer is formed by the peroxide sterilized water-based organic ink in the technical scheme.
Preferably, the thickness of the color-changeable ink layer is 3 to 15 filaments.
Preferably, the protective layer is an organic coating layer or an anti-sticking layer.
The invention provides peroxide sterilization water-based organic ink and a preparation method and application thereof, wherein the peroxide sterilization water-based organic ink is prepared from the following raw materials: 10-45 wt% of connecting material; 0.1 wt% -2 wt% of organic dye; 1 to 20 weight percent of alkaline control agent; 50 wt% -75 wt% of aqueous system solvent; the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol. Compared with the prior art, the peroxide sterilization water-based organic ink provided by the invention adopts a water-based system solvent, is matched with other components with specific contents, realizes better interaction, has the advantages of low VOCs (volatile organic compounds) emission, no heavy metal and avoidance of heavy metal pollution, and can be widely applied to printing of products such as indicator cards, indicator labels (adhesive tapes), paper plastic bags and the like, and the color of the products can be changed after the products are sterilized by peroxide, thereby playing an indicating role.
In addition, the peroxide sterilization water-based organic ink changes color according to the mutation principle, has visual and accurate indication effect, is clearer and clearer, and avoids subjective factors judged by medical staff; meanwhile, the monitoring is simple and easy, and the monitoring sterilization time can be adjusted.
Drawings
FIG. 1 is a schematic diagram showing the indicating effect of the chemical indicator card for peroxide sterilization in example 1 of the present invention;
FIG. 2 is a schematic diagram showing the indicating effect of the chemical indicator label for peroxide sterilization in example 2 of the present invention;
fig. 3 is a schematic diagram showing the indicating effect of the peroxide sterilization chemical indicator tape in example 3 of the present invention.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides peroxide sterilization water-based organic ink which is prepared from the following raw materials:
10-45 wt% of connecting material;
0.1 wt% -2 wt% of organic dye;
1 to 20 weight percent of alkaline control agent;
50 wt% -75 wt% of aqueous system solvent;
the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol.
In the invention, the peroxide sterilized aqueous organic ink comprises a binder, an organic dye, a basic control agent and an aqueous system solvent, and preferably consists of the binder, the organic dye, the basic control agent and the aqueous system solvent. In the present invention, the binder is preferably selected from one or more of acrylic resin, polyvinyl alcohol resin, polyurethane resin, alkyd resin and rosin resin, and more preferably acrylic resin, polyvinyl alcohol resin or polyurethane resin. The present invention is not particularly limited in its source, and commercially available products of the above-mentioned acrylic resin, polyvinyl alcohol resin, polyurethane resin, alkyd resin and rosin resin, which are well known to those skilled in the art, may be used. In the invention, the peroxide sterilized aqueous organic ink comprises 10 wt% -45 wt% of the binder, preferably 25 wt% -40 wt%.
In the present invention, the organic dye is preferably selected from one or more of indigo, basic blue, basic royal blue, basic brilliant blue and basic lake blue, and more preferably basic blue, basic royal blue or basic brilliant blue. The source of the organic dye is not particularly limited in the present invention, and commercially available products of indigo, basic blue, basic royal blue, basic brilliant blue and basic lake blue, which are well known to those skilled in the art, may be used. In the invention, the peroxide sterilized water-based organic ink comprises 0.1-2 wt% of organic dye, and preferably 0.5-1 wt%. Therefore, the consumption of the organic dye in the peroxide sterilized water-based organic ink provided by the invention is less.
In the present invention, the alkali control agent is preferably selected from one or more of ammonia, ethanolamine, methylamine, ethylamine, propylamine, aniline, cyclohexylamine, and tetrabutylammonium bromide, and more preferably aniline, cyclohexylamine, or tetrabutylammonium bromide. The source of the alkali control agent in the present invention is not particularly limited, and commercially available products of the above-mentioned aqueous ammonia, ethanolamine, methylamine, ethylamine, propylamine, aniline, cyclohexylamine and tetrabutylammonium bromide, which are well known to those skilled in the art, may be used. In the invention, the peroxide sterilized aqueous organic ink comprises 1-20 wt% of alkali control agent, preferably 3-15 wt%.
In the present invention, the aqueous system solvent consists of water and an organic solvent; wherein the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol, preferably ethanol, n-propanol or isopropanol. The source of the organic solvent is not particularly limited in the present invention, and commercially available products of the above-mentioned methanol, ethanol, n-propanol, isopropanol and n-butanol, which are well known to those skilled in the art, may be used. In the present invention, the mass ratio of water to the organic solvent in the aqueous system solvent is preferably 3: (2-10), more preferably 3: (2.5-6).
Compared with the solvent type ink system (comprising high-hazard substances such as toluene, xylene, butyl acetate, cyclohexanone and the like, and all organic solvents) in the prior art, the aqueous system solvent is low in hazard, low in VOCs discharge amount and environment-friendly. In the invention, the peroxide sterilized aqueous organic ink comprises 50 wt% -75 wt% of aqueous system solvent, and preferably 55 wt% -70 wt%.
The peroxide sterilization water-based organic ink provided by the invention adopts a water-based system solvent, is matched with other components with specific contents, realizes better interaction, can be well applied to various printed matters, is very convenient to use, can change color after peroxide sterilization, further plays an indicating role, has the advantages of low VOCs (volatile organic compounds) emission, no heavy metal, avoidance of heavy metal pollution, reduction of infection risk and wide application in printing of products such as indicator cards, indicator labels (adhesive tapes), paper-plastic bags and the like, and can be widely applied to printing of products such as indicator cards, indicator labels (adhesive tapes), paper-plastic bags and the like.
The invention also provides a preparation method of the peroxide sterilization water-based organic ink, which comprises the following steps:
a) dissolving the binder in an aqueous system solvent, sequentially adding the organic dye and the alkali control agent, and mixing to obtain the peroxide sterilized aqueous organic ink.
In the present invention, the binder, the aqueous system solvent, the organic dye and the alkalinity controlling agent are the same as those described in the above technical solution, and are not described herein again.
In the present invention, the mixing mode is preferably stirring, and both the technical schemes of manual stirring or mechanical stirring well known to those skilled in the art can be adopted; the stirring temperature is preferably 15-35 ℃, and more preferably 25 ℃; the rotating speed of the stirring is preferably 10 r/min-50 r/min, and more preferably 30 r/min; the stirring time is preferably 3 to 6 hours, and more preferably 4 to 5 hours.
The preparation method provided by the invention is simple in process, mild in condition and suitable for large-scale industrial production.
The present invention also provides an indicator material for peroxide sterilization monitoring comprising:
a substrate;
a color-changeable ink layer compounded on the substrate;
a protective layer compounded on the color-changeable ink layer;
the color-changeable ink layer is formed by the peroxide sterilized water-based organic ink in the technical scheme.
In the present invention, the substrate preferably comprises PET plastic, PP plastic or tyvek paper; further obtained indicating materials comprise products such as indicating cards, labels, adhesive tapes, paper-plastic bags and the like.
In the invention, the color-changeable ink layer is formed by the peroxide-sterilized aqueous organic ink described in the above technical scheme; the formation may be by flexographic or gravure printing followed by drying as is well known to those skilled in the art. In the present invention, the temperature for the drying is preferably 40 to 70 ℃, more preferably 60 ℃.
In the present invention, the thickness of the variable color ink layer is preferably 3 to 15 filaments, and more preferably 8 to 10 filaments.
In the present invention, the protective layer is preferably an organic coating layer or an anti-sticking layer; wherein, the organic coating layer is preferably an ethyl cellulose membrane; the color-changeable ink is formed by forming a film through ethyl cellulose, and mainly has the functions of preventing the color-changeable ink layer from contacting with an instrument and reducing pollution; the anti-sticking layer is preferably prepared by an anti-sticking agent. In the present invention, the thickness of the protective layer is preferably 5 to 8 filaments.
The peroxide sterilization water-based organic ink provided by the invention changes color by a mutation principle, and the indicating material using the peroxide sterilization water-based organic ink has visual and accurate indicating effect, is clearer and clearer, and avoids subjective factors judged by medical personnel; meanwhile, the monitoring is simple and easy, and the monitoring sterilization time can be adjusted.
The invention provides peroxide sterilization water-based organic ink and a preparation method and application thereof, wherein the peroxide sterilization water-based organic ink is prepared from the following raw materials: 10-45 wt% of connecting material; 0.1 wt% -2 wt% of organic dye; 1 to 20 weight percent of alkaline control agent; 50 wt% -75 wt% of aqueous system solvent; the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol. Compared with the prior art, the peroxide sterilization water-based organic ink provided by the invention adopts a water-based system solvent, is matched with other components with specific contents, realizes better interaction, has the advantages of low VOCs (volatile organic compounds) emission, no heavy metal and avoidance of heavy metal pollution, and can be widely applied to printing of products such as indicator cards, indicator labels (adhesive tapes), paper plastic bags and the like, and the color of the products can be changed after the products are sterilized by peroxide, thereby playing an indicating role.
In addition, the peroxide sterilization water-based organic ink changes color according to the mutation principle, has visual and accurate indication effect, is clearer and clearer, and avoids subjective factors judged by medical staff; meanwhile, the monitoring is simple and easy, and the monitoring sterilization time can be adjusted.
To further illustrate the present invention, the following examples are provided for illustration. The raw materials used in the following examples of the present invention are all commercially available products.
Example 1
(1) The formula comprises the following components:
40 wt% of polyurethane resin;
20 wt% of water;
0.5 wt% of basic blue;
3 wt% of aniline;
36.5 wt% of isopropanol.
(2) The preparation process comprises the following steps:
dissolving polyurethane resin in a mixed solution of water and isopropanol, adding alkaline product blue, adding aniline, and stirring at 25 ℃ and 30r/min for 4-5 h to obtain the peroxide sterilized water-based organic ink.
The peroxide sterilization water-based organic ink provided by the embodiment 1 of the invention is coated on PP plastic by a flexible printing mode, the coating speed is 25m/min, the drying temperature is 60 ℃, an ink layer with the thickness of 8-10 filaments is formed, then an ethyl cellulose film is adopted to coat the ink layer, and the peroxide sterilization chemical indicator card is further used for a peroxide sterilization program, and the result shows that after the peroxide sterilization chemical indicator card is used for the peroxide sterilization program, the color is changed from blue to colorless under the condition that the concentration of hydrogen peroxide and peracetic acid is 2.3 mg/L, and the condition is shown in figure 1.
As can be seen from the figure 1, after the peroxide sterilization chemical indicator card is used in a peroxide sterilization procedure, the color change based on a mutation principle (non-uniform color change, no intermediate color change) is realized, the color change based on a non-gradual change principle is realized, the indicating effect is visual and accurate, the clarity is higher, and the artificial subjective factors of medical personnel are reduced.
Example 2
(1) The formula comprises the following components:
29 wt% of acrylic resin;
1 wt% of basic blue;
15 wt% of tetrabutylammonium bromide;
25 wt% of ethanol;
30 wt% of water.
(2) The preparation process comprises the following steps:
dissolving acrylic resin in a mixed solution of ethanol and water, adding alkaline blue, then adding tetrabutylammonium bromide, and stirring for 4-5 h to obtain the peroxide sterilized water-based organic ink.
The peroxide sterilization water-based organic ink provided by the embodiment 2 of the invention is coated on PET plastic by a gravure printing mode, the coating speed is 25m/min, the drying temperature is 60 ℃, an ink layer with the thickness of 8-10 threads is formed, then an ethyl cellulose film is adopted to coat the ink layer, and a peroxide object sterilization chemical indicator label is obtained and is further used for a peroxide sterilization program, and the result shows that after the peroxide sterilization chemical indicator label is used for the peroxide sterilization program, the color is changed from blue to colorless under the condition that the concentration of hydrogen peroxide and peracetic acid is 2.3 mg/L, and the color is shown in figure 2.
Example 3
(1) The formula comprises the following components:
25 wt% of polyvinyl alcohol resin;
1 wt% of alkaline brilliant blue;
4 wt% of cyclohexylamine;
30 wt% of water;
40 wt% of n-propanol.
(2) The preparation process comprises the following steps:
and dissolving polyvinyl acetal in a mixed solution of water and n-propanol, adding alkaline brilliant blue, then adding cyclohexylamine, and stirring for 4-5 hours to obtain the peroxide sterilized aqueous organic ink.
The peroxide sterilization water-based organic ink provided by the embodiment 3 of the invention is coated on PET plastic paper by a gravure printing mode, the coating speed is 25m/min, the drying temperature is 60 ℃, an ink layer with the thickness of 8-10 threads is formed, then a silicon anti-sticking agent is coated on the ink layer to form an anti-sticking layer, the peroxide sterilization chemical indicator tape is further used for a peroxide sterilization procedure, and the result shows that after the peroxide sterilization chemical indicator tape is used for the peroxide sterilization procedure, the color is changed from blue to colorless under the condition that the concentration of hydrogen peroxide and peracetic acid is 2.3 mg/L, and the color is shown in figure 3.
The peroxide sterilization water-based organic ink provided by the invention adopts a water-based system, and has the advantage of low VOCs emission; meanwhile, the medical nursing liquid does not contain heavy metals, so that the exposure risk of lead and other metals of medical personnel is avoided, and the infection risk can be reduced; and the color is changed by the mutation principle, so that subjective factors judged by medical personnel are avoided.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein (e.g., non-color shifting dyes may be added to adjust for initial and final color shifts; this is also within the scope of patent protection).
Claims (10)
1. The peroxide sterilization water-based organic ink is prepared from the following raw materials:
10-45 wt% of connecting material;
0.1 wt% -2 wt% of organic dye;
1 to 20 weight percent of alkaline control agent;
50 wt% -75 wt% of aqueous system solvent;
the aqueous system solvent consists of water and an organic solvent; the organic solvent is selected from one or more of methanol, ethanol, n-propanol, isopropanol and n-butanol.
2. A peroxide-curable aqueous organic ink according to claim 1, wherein the binder is selected from one or more of acrylic resins, polyvinyl alcohol resins, polyurethane resins, alkyd resins and rosin resins.
3. A peroxide-sterilized aqueous organic ink as claimed in claim 1, wherein the organic dye is selected from one or more of indigo, basic blue, basic royal blue, basic brilliant blue and basic lake blue.
4. A peroxide-sterilized aqueous organic ink as set forth in claim 1, wherein the alkali-controlling agent is selected from one or more of ammonia, ethanolamine, methylamine, ethylamine, propylamine, aniline, cyclohexylamine, and tetrabutylammonium bromide.
5. The peroxide-sterilized aqueous organic ink according to claim 1, wherein the mass ratio of water to the organic solvent in the aqueous solvent system is 3: (2-10).
6. A method for preparing the peroxide-sterilized aqueous organic ink according to any one of claims 1 to 5, comprising the steps of:
a) dissolving the binder in an aqueous system solvent, sequentially adding the organic dye and the alkali control agent, and mixing to obtain the peroxide sterilized aqueous organic ink.
7. The method according to claim 6, wherein the mixing in step a) is performed by stirring; the stirring temperature is 15-35 ℃, the rotating speed is 10-50 r/min, and the time is 3-6 h.
8. An indicator material for peroxide sterilization monitoring comprising:
a substrate;
a color-changeable ink layer compounded on the substrate;
a protective layer compounded on the color-changeable ink layer;
the color-changeable ink layer is formed by the peroxide-sterilized aqueous organic ink according to any one of claims 1 to 5.
9. The indicator material for peroxide sterilization monitoring according to claim 8, wherein the thickness of the color-changeable ink layer is 3 to 15 filaments.
10. An indicator material for peroxide sterilisation monitoring according to claim 8, characterised in that the protective layer is an organic coating layer or an anti-adhesive layer.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113429835A (en) * | 2021-07-22 | 2021-09-24 | 山东新华医疗器械股份有限公司 | Pressure steam sterilization water-based organic ink and preparation method and application thereof |
| CN115093747A (en) * | 2022-07-14 | 2022-09-23 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105623375A (en) * | 2016-02-25 | 2016-06-01 | 深圳九星印刷包装集团有限公司 | Color change indicating device and transparent printing ink |
| CN107652780A (en) * | 2017-09-01 | 2018-02-02 | 深圳洁康医疗器材有限公司 | A kind of environment-friendly type color shifting ink of hydrogen peroxide low-temperature plasma sterilizing |
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2020
- 2020-06-03 CN CN202010494250.0A patent/CN111471346A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105623375A (en) * | 2016-02-25 | 2016-06-01 | 深圳九星印刷包装集团有限公司 | Color change indicating device and transparent printing ink |
| CN107652780A (en) * | 2017-09-01 | 2018-02-02 | 深圳洁康医疗器材有限公司 | A kind of environment-friendly type color shifting ink of hydrogen peroxide low-temperature plasma sterilizing |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113429835A (en) * | 2021-07-22 | 2021-09-24 | 山东新华医疗器械股份有限公司 | Pressure steam sterilization water-based organic ink and preparation method and application thereof |
| CN115093747A (en) * | 2022-07-14 | 2022-09-23 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
| CN115093747B (en) * | 2022-07-14 | 2022-11-08 | 山东新华医疗器械股份有限公司 | Chemical indicating ink for pressure steam sterilization and preparation method thereof |
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