JP2001527402A - Ｎｇｆ変異体 - Google Patents
Ｎｇｆ変異体Info
- Publication number
- JP2001527402A JP2001527402A JP54714498A JP54714498A JP2001527402A JP 2001527402 A JP2001527402 A JP 2001527402A JP 54714498 A JP54714498 A JP 54714498A JP 54714498 A JP54714498 A JP 54714498A JP 2001527402 A JP2001527402 A JP 2001527402A
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- ngf
- binding
- trkc
- mutant
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- 125000000341 threoninyl group Chemical group [H]OC([H])(C([H])([H])[H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 230000005026 transcription initiation Effects 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 239000010981 turquoise Substances 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/845,541 | 1997-04-25 | ||
| US08/845,541 US6333310B1 (en) | 1994-06-03 | 1997-04-25 | NGF variants |
| US84104597A | 1997-04-29 | 1997-04-29 | |
| US08/841,045 | 1997-04-29 | ||
| PCT/US1998/008242 WO1998049308A1 (en) | 1997-04-25 | 1998-04-23 | Ngf variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2001527402A true JP2001527402A (ja) | 2001-12-25 |
Family
ID=27126232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54714498A Ceased JP2001527402A (ja) | 1997-04-25 | 1998-04-23 | Ｎｇｆ変異体 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0977860A1 (de) |
| JP (1) | JP2001527402A (de) |
| AU (2) | AU7154698A (de) |
| CA (1) | CA2286558A1 (de) |
| IL (1) | IL132251A0 (de) |
| WO (1) | WO1998049308A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6683058B1 (en) | 1998-04-15 | 2004-01-27 | Regents Of The University Of California | Methods for therapy of neurodegenerative disease of the brain |
| US6656474B1 (en) * | 1999-01-15 | 2003-12-02 | Regeneron Pharmaceuticals, Inc. | Methods of using a neurotrophin and its analogues for the treatment of gastrointestinal hypomotility disorders |
| NZ523105A (en) | 2000-06-22 | 2004-07-30 | Genentech Inc | Agonist anti-trk-C monoclonal antibodies |
| AU6175801A (en) | 2000-07-19 | 2002-02-05 | Univ California | Methods for therapy of neurodegenerative disease of the brain |
| EP1620127A4 (de) * | 2003-03-20 | 2007-04-04 | Rinat Neuroscience Corp | Verfahren zur behandlung von taxol-induzierten darmstörungen |
| EP1689865A2 (de) * | 2003-10-23 | 2006-08-16 | Monika Holmberg | Neues mutiertes gen für nervenwachstumsfaktor-beta, davon codierte proteine sowie produkte und verfahren in verbindung damit |
| US8309057B2 (en) * | 2005-06-10 | 2012-11-13 | The Invention Science Fund I, Llc | Methods for elevating neurotrophic agents |
| ITRM20060367A1 (it) * | 2006-07-13 | 2008-01-14 | Lay Line Genomics Spa | Muteine del hngf usi terapeutici e composizioni farmaceutiche |
| IT201800009384A1 (it) * | 2018-10-11 | 2020-04-11 | Cosmo Srl | Peptide for cosmetic application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728803A (en) * | 1994-06-03 | 1998-03-17 | Genentech, Inc. | Pantropic neurotrophic factors |
-
1998
- 1998-04-23 IL IL13225198A patent/IL132251A0/xx unknown
- 1998-04-23 JP JP54714498A patent/JP2001527402A/ja not_active Ceased
- 1998-04-23 CA CA002286558A patent/CA2286558A1/en not_active Abandoned
- 1998-04-23 AU AU71546/98A patent/AU7154698A/en not_active Abandoned
- 1998-04-23 EP EP98918666A patent/EP0977860A1/de not_active Withdrawn
- 1998-04-23 WO PCT/US1998/008242 patent/WO1998049308A1/en not_active Application Discontinuation
-
2002
- 2002-08-01 AU AU2002300365A patent/AU2002300365B9/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL132251A0 (en) | 2001-03-19 |
| EP0977860A1 (de) | 2000-02-09 |
| AU2002300365B9 (en) | 2007-03-15 |
| CA2286558A1 (en) | 1998-11-05 |
| WO1998049308A1 (en) | 1998-11-05 |
| AU7154698A (en) | 1998-11-24 |
| AU2002300365A1 (en) | 2003-01-30 |
| AU2002300365B2 (en) | 2006-07-13 |
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