JP2001525172A5 - - Google Patents

Info

Publication number

JP2001525172A5

JP2001525172A5 JP2000523343A JP2000523343A JP2001525172A5 JP 2001525172 A5 JP2001525172 A5 JP 2001525172A5 JP 2000523343 A JP2000523343 A JP 2000523343A JP 2000523343 A JP2000523343 A JP 2000523343A JP 2001525172 A5 JP2001525172 A5 JP 2001525172A5

Authority

JP

Japan

Prior art keywords

amino acid

seq

sequence

polypeptide

asp

Prior art date

1998-12-01

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000001413 amino acids Chemical class 0.000 description 61
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 24
• 125000003275 alpha amino acid group Chemical group 0.000 description 23
• 229920001184 polypeptide Polymers 0.000 description 23
• 108090000765 processed proteins & peptides Proteins 0.000 description 23
• 102000004196 processed proteins & peptides Human genes 0.000 description 23
• 125000000539 amino acid group Chemical group 0.000 description 13
• 239000002773 nucleotide Substances 0.000 description 13
• 125000003729 nucleotide group Chemical group 0.000 description 13
• 239000002157 polynucleotide Substances 0.000 description 10
• 102000040430 polynucleotide Human genes 0.000 description 10
• 108091033319 polynucleotide Proteins 0.000 description 10
• 210000004027 cell Anatomy 0.000 description 7
• 238000000034 method Methods 0.000 description 7
• 239000013604 expression vector Substances 0.000 description 5
• 108010076504 Protein Sorting Signals Proteins 0.000 description 2
• 108700008625 Reporter Genes Proteins 0.000 description 2
• 239000000556 agonist Substances 0.000 description 2
• 239000005557 antagonist Substances 0.000 description 2
• 238000004166 bioassay Methods 0.000 description 2
• 238000010256 biochemical assay Methods 0.000 description 2
• 230000000694 effects Effects 0.000 description 2
• 108020001507 fusion proteins Proteins 0.000 description 2
• 102000037865 fusion proteins Human genes 0.000 description 2
• 238000004519 manufacturing process Methods 0.000 description 2
• 230000037361 pathway Effects 0.000 description 2
• 230000004952 protein activity Effects 0.000 description 2
• 230000004044 response Effects 0.000 description 2
• 230000003248 secreting effect Effects 0.000 description 2
• 238000013518 transcription Methods 0.000 description 2
• 230000035897 transcription Effects 0.000 description 2
• 230000000295 complement effect Effects 0.000 description 1
• 210000004748 cultured cell Anatomy 0.000 description 1
• 230000028993 immune response Effects 0.000 description 1