|
US6063561A
(en)
*
|
1991-01-17 |
2000-05-16 |
Abbott Laboratories |
Polyketide derivatives and recombinant methods for making same
|
|
US6066721A
(en)
*
|
1995-07-06 |
2000-05-23 |
Stanford University |
Method to produce novel polyketides
|
|
US6495348B1
(en)
|
1993-10-07 |
2002-12-17 |
Regents Of The University Of Minnesota |
Mitomycin biosynthetic gene cluster
|
|
US6399789B1
(en)
|
1996-12-18 |
2002-06-04 |
Kosan Biosciences, Inc. |
Multi-plasmid method for preparing large libraries of polyketides and non-ribosomal peptides
|
|
GB9814006D0
(en)
*
|
1998-06-29 |
1998-08-26 |
Biotica Tech Ltd |
Polyketides and their synthesis
|
|
JP2002525026A
(ja)
|
1998-07-02 |
2002-08-13 |
ザ ボード オブ リージェンツ オブ ザ レランド スタンフォード ジュニア ユニバーシティ |
ポリケチドを作製するための方法
|
|
CA2343880C
(en)
*
|
1998-10-02 |
2008-08-26 |
Kosan Biosciences, Inc. |
Polyketide synthase enzymes and recombinant dna constructs therefor
|
|
JP2002528467A
(ja)
*
|
1998-10-28 |
2002-09-03 |
コーサン バイオサイエンシーズ, インコーポレイテッド |
新規な「不自然な(unnatural)」天然生成物のライブラリ
|
|
EP1135470A2
(en)
|
1998-11-20 |
2001-09-26 |
Kosan Biosciences, Inc. |
Recombinant methods and materials for producing epothilone and epothilone derivatives
|
|
US6410301B1
(en)
|
1998-11-20 |
2002-06-25 |
Kosan Biosciences, Inc. |
Myxococcus host cells for the production of epothilones
|
|
US6358712B1
(en)
|
1999-01-05 |
2002-03-19 |
Trustee Of Boston University |
Ordered gene assembly
|
|
EP1141275B1
(en)
|
1999-01-05 |
2009-08-12 |
Trustees Of Boston University |
Improved nucleic acid cloning
|
|
WO2000044717A2
(en)
*
|
1999-01-27 |
2000-08-03 |
Kosan Biosciences, Inc. |
Synthesis of oligoketides
|
|
EP1754700A3
(en)
*
|
1999-01-27 |
2007-05-09 |
Kosan Biosciences, Inc. |
Synthesis of oligoketides
|
|
CA2359801A1
(en)
*
|
1999-02-09 |
2000-08-17 |
Rajesh S. Gokhale |
Methods to mediate polyketide synthase module effectiveness
|
|
US7001748B2
(en)
|
1999-02-09 |
2006-02-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of making polyketides using hybrid polyketide synthases
|
|
US6451768B1
(en)
|
1999-04-16 |
2002-09-17 |
Kosan Biosciences, Inc. |
Macrolide antiinfective agents
|
|
CN1373767A
(zh)
*
|
1999-04-16 |
2002-10-09 |
奥索-麦克尼尔药品公司 |
酮式大环内酯抗菌剂
|
|
DE60028956T2
(de)
*
|
1999-04-16 |
2006-11-30 |
Kosan Biosciences, Inc., Hayward |
Multi-plasmid verfahren zur herstellung von grossen bibliotheken von polyketiden und nicht-ribosomalen peptiden
|
|
US6590083B1
(en)
|
1999-04-16 |
2003-07-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Ketolide antibacterials
|
|
GB9912563D0
(en)
*
|
1999-05-28 |
1999-07-28 |
Biotica Tech Ltd |
Polyketides and their synthesis
|
|
GB9913694D0
(en)
*
|
1999-06-11 |
1999-08-11 |
Simper Adrian M |
DNA manipulation methods and applications for synthetic enzymes
|
|
US6569867B2
(en)
|
1999-10-01 |
2003-05-27 |
Kosan Biosciences, Inc. |
Polyketide derivatives
|
|
US7033818B2
(en)
|
1999-10-08 |
2006-04-25 |
Kosan Biosciences, Inc. |
Recombinant polyketide synthase genes
|
|
US6524841B1
(en)
|
1999-10-08 |
2003-02-25 |
Kosan Biosciences, Inc. |
Recombinant megalomicin biosynthetic genes and uses thereof
|
|
DE60026563D1
(de)
|
1999-10-25 |
2006-05-04 |
Kosan Biosciences Inc |
Herstellung von polyketiden
|
|
MXPA02004153A
(es)
|
1999-10-27 |
2002-10-17 |
Kosan Biosciences Inc |
Produccion heterologa de policetidos.
|
|
ATE356880T1
(de)
|
1999-10-29 |
2007-04-15 |
Kosan Biosciences Inc |
Rapamycin analoge
|
|
WO2001059126A2
(en)
|
2000-02-08 |
2001-08-16 |
Norges Teknisk Naturvitenskapelige Universitet |
Gene cluster encoding a nystatin polyketide synthase and its manipulation and utility
|
|
WO2001079520A1
(en)
*
|
2000-04-13 |
2001-10-25 |
Biotica Technology Limited |
Hybrid glycosylated products and their production and use
|
|
US6838265B2
(en)
|
2000-05-02 |
2005-01-04 |
Kosan Biosciences, Inc. |
Overproduction hosts for biosynthesis of polyketides
|
|
AU2001275012A1
(en)
|
2000-05-30 |
2001-12-11 |
Kosan Biosciences, Inc. |
Design of polyketide synthase genes
|
|
WO2002099113A1
(en)
*
|
2001-06-01 |
2002-12-12 |
Ajinomoto Co., Inc. |
Macrolide compounds, antifungal agents using the same, macrolide compound-producing bacterium belonging to the genus sorangium and process for producing macrolide compounds using the same
|
|
US7189549B2
(en)
*
|
2002-06-14 |
2007-03-13 |
Kosan Biosciences, Inc. |
Recombinant polynucleotides encoding pro-geldanamycin producing polyketide synthase and accessory proteins, and uses thereof
|
|
US7427493B2
(en)
|
2002-06-28 |
2008-09-23 |
Kosan Biosciences Incorporated |
Recombinant genes for polyketide modifying enzymes
|
|
KR100549690B1
(ko)
|
2003-10-23 |
2006-02-07 |
상하이 지아오통 대학 |
에프알-008 폴리케타이드 합성에 관여하는 유전자
|
|
EP1751279A4
(en)
|
2004-05-05 |
2008-03-19 |
Univ Minnesota |
NUCLEIC ACIDS AND POLYPEPTIDES INVOLVED IN THE PREPARATION OF CRYPTOPHYCIN
|
|
US20050272166A1
(en)
*
|
2004-05-06 |
2005-12-08 |
Li Jin |
Methods and systems for detection, identification and quantitation of macrolides and their impurities
|
|
US7566558B2
(en)
|
2006-07-28 |
2009-07-28 |
Regents Of The University Of Michigan |
Nucleic acids and polypeptides involved in the production of cryptophycin
|
|
US8759031B2
(en)
|
2007-04-12 |
2014-06-24 |
Wisconsin Alumni Research Foundation |
Type I polyketide synthase extender units
|
|
WO2009121066A1
(en)
|
2008-03-28 |
2009-10-01 |
The Regents Of The University Of California |
Producing dicarboxylic acids using polyketide synthases
|
|
CN102014623A
(zh)
*
|
2008-04-29 |
2011-04-13 |
加利福尼亚大学董事会 |
使用聚酮化物合酶制备生物燃料
|
|
US8852902B2
(en)
|
2010-11-22 |
2014-10-07 |
The Regents Of The University Of California |
Producing a trimethylpentanoic acid using hybrid polyketide synthases
|
|
GB201312318D0
(en)
*
|
2013-07-09 |
2013-08-21 |
Isomerase Therapeutics Ltd |
Novel methods and compounds
|
|
US10233431B2
(en)
|
2014-02-26 |
2019-03-19 |
The Regents Of The University Of California |
Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
|
|
CN112301005B
(zh)
*
|
2020-11-09 |
2023-01-24 |
浙江大学 |
一种6-脱氧赤酮酸内酯b合酶复合体3的制备方法
|