JP2001522794A5 - - Google Patents
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- Publication number
- JP2001522794A5 JP2001522794A5 JP2000520110A JP2000520110A JP2001522794A5 JP 2001522794 A5 JP2001522794 A5 JP 2001522794A5 JP 2000520110 A JP2000520110 A JP 2000520110A JP 2000520110 A JP2000520110 A JP 2000520110A JP 2001522794 A5 JP2001522794 A5 JP 2001522794A5
- Authority
- JP
- Japan
- Prior art keywords
- carvedilol
- formulation
- hmpc
- carbopol
- angina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 description 6
- NPAKNKYSJIDKMW-UHFFFAOYSA-N carvedilol Chemical compound COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=NC3=CC=C[CH]C3=C12 NPAKNKYSJIDKMW-UHFFFAOYSA-N 0.000 description 4
- 229960004195 carvedilol Drugs 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 206010002383 Angina Pectoris Diseases 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 229920001477 hydrophilic polymer Polymers 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6545697P | 1997-11-12 | 1997-11-12 | |
| US60/065,456 | 1997-11-12 | ||
| PCT/US1998/024102 WO1999024017A1 (en) | 1997-11-12 | 1998-11-12 | Novel oral dosage form for carvedilol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001522794A JP2001522794A (ja) | 2001-11-20 |
| JP2001522794A5 true JP2001522794A5 (enExample) | 2006-01-05 |
Family
ID=22062830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000520110A Pending JP2001522794A (ja) | 1997-11-12 | 1998-11-12 | カルベジロールの新規経口剤形 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1030651A4 (enExample) |
| JP (1) | JP2001522794A (enExample) |
| KR (1) | KR20010031952A (enExample) |
| CN (1) | CN1285738A (enExample) |
| AU (1) | AU751117B2 (enExample) |
| BR (1) | BR9814127A (enExample) |
| CA (1) | CA2309542A1 (enExample) |
| HU (1) | HUP0004345A3 (enExample) |
| IL (1) | IL136028A0 (enExample) |
| NO (1) | NO20002439L (enExample) |
| NZ (1) | NZ504418A (enExample) |
| PL (1) | PL340456A1 (enExample) |
| TR (1) | TR200001362T2 (enExample) |
| WO (1) | WO1999024017A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040151772A1 (en) | 2002-11-08 | 2004-08-05 | Egalet A/S | Controlled release carvedilol compositions |
| AU2003288608A1 (en) * | 2002-12-20 | 2004-07-14 | Ranbaxy Laboratories Limited | Controlled release, multiple unit drug delivery systems |
| US20050169994A1 (en) * | 2003-11-25 | 2005-08-04 | Burke Matthew D. | Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods |
| WO2005051322A2 (en) * | 2003-11-25 | 2005-06-09 | Sb Pharmco Puerto Rico Inc. | Controlled release pharmaceutical formulations comprising carvedilol, free based and its salts |
| EP2010162A4 (en) * | 2006-04-03 | 2013-01-09 | Isa Odidi | COMPOSITION FOR DISPOSING A MEDICINAL PRODUCT |
| TWI415604B (zh) | 2009-09-29 | 2013-11-21 | Tsh Biopharm Corp Ltd | 調控釋放卡菲蒂羅劑型 |
| EP2540294B1 (en) * | 2010-02-22 | 2016-08-03 | Daiichi Sankyo Company, Limited | Sustained-release solid preparation for oral use |
| WO2011102504A1 (ja) * | 2010-02-22 | 2011-08-25 | 第一三共株式会社 | 経口用徐放性固形製剤 |
| WO2011102505A1 (ja) * | 2010-02-22 | 2011-08-25 | 第一三共株式会社 | 経口用徐放性固形製剤 |
| KR102127625B1 (ko) | 2012-09-03 | 2020-06-29 | 다이이찌 산쿄 가부시키가이샤 | 하이드로모르폰염산염 함유의 경구용 서방성 의약 조성물 |
| KR102158339B1 (ko) * | 2016-02-05 | 2020-09-21 | 삼진제약주식회사 | 인습성이 개선된 카르베딜롤 속방성 제제 |
| KR102525298B1 (ko) | 2020-12-30 | 2023-04-25 | 단국대학교 천안캠퍼스 산학협력단 | 경구 생체이용률이 증가된 주석산을 포함하는 카베디롤 함유 고체분산체 및 이의 제조방법 |
| KR102492147B1 (ko) | 2020-12-30 | 2023-01-26 | 단국대학교 천안캠퍼스 산학협력단 | 자가나노유화 약물전달 시스템을 이용한 카베디롤 함유 경구용 고형제제 조성물 및 이의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| JPS5598120A (en) * | 1979-01-16 | 1980-07-25 | Shin Etsu Chem Co Ltd | Preparation of drug having enteric coating |
| CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
| US4680323A (en) * | 1983-12-01 | 1987-07-14 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration |
| ATE134300T1 (de) * | 1990-10-23 | 1996-03-15 | Davband Pty Ltd | Rückenunterstützung für einen stuhl oder sitz |
| US5760069A (en) * | 1995-02-08 | 1998-06-02 | Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 | Method of treatment for decreasing mortality resulting from congestive heart failure |
| DE19637082A1 (de) * | 1996-09-12 | 1998-03-19 | Boehringer Mannheim Gmbh | Schnellzerfallende Pellets |
-
1998
- 1998-11-12 WO PCT/US1998/024102 patent/WO1999024017A1/en not_active Ceased
- 1998-11-12 KR KR1020007005059A patent/KR20010031952A/ko not_active Ceased
- 1998-11-12 AU AU14569/99A patent/AU751117B2/en not_active Ceased
- 1998-11-12 CN CN98813082A patent/CN1285738A/zh active Pending
- 1998-11-12 EP EP98958546A patent/EP1030651A4/en not_active Withdrawn
- 1998-11-12 IL IL13602898A patent/IL136028A0/xx not_active IP Right Cessation
- 1998-11-12 NZ NZ504418A patent/NZ504418A/xx unknown
- 1998-11-12 TR TR2000/01362T patent/TR200001362T2/xx unknown
- 1998-11-12 JP JP2000520110A patent/JP2001522794A/ja active Pending
- 1998-11-12 HU HU0004345A patent/HUP0004345A3/hu unknown
- 1998-11-12 BR BR9814127-9A patent/BR9814127A/pt not_active IP Right Cessation
- 1998-11-12 CA CA002309542A patent/CA2309542A1/en not_active Abandoned
- 1998-11-12 PL PL98340456A patent/PL340456A1/xx unknown
-
2000
- 2000-05-11 NO NO20002439A patent/NO20002439L/no unknown
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