JP2001522369A5 - - Google Patents

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Publication number
JP2001522369A5
JP2001522369A5 JP1998546732A JP54673298A JP2001522369A5 JP 2001522369 A5 JP2001522369 A5 JP 2001522369A5 JP 1998546732 A JP1998546732 A JP 1998546732A JP 54673298 A JP54673298 A JP 54673298A JP 2001522369 A5 JP2001522369 A5 JP 2001522369A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998546732A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001522369A (ja
JP4514242B2 (ja
Filing date
Publication date
Priority claimed from GBGB9708611.0A external-priority patent/GB9708611D0/en
Application filed filed Critical
Publication of JP2001522369A publication Critical patent/JP2001522369A/ja
Publication of JP2001522369A5 publication Critical patent/JP2001522369A5/ja
Application granted granted Critical
Publication of JP4514242B2 publication Critical patent/JP4514242B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP54673298A 1997-04-28 1998-04-27 抗ウイルスピリミジンヌクレオシド類似体 Expired - Lifetime JP4514242B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9708611.0 1997-04-28
GBGB9708611.0A GB9708611D0 (en) 1997-04-28 1997-04-28 Chemical compounds
PCT/GB1998/001222 WO1998049177A1 (en) 1997-04-28 1998-04-27 Anti-viral pyrimidine nucleoside analogues

Publications (3)

Publication Number Publication Date
JP2001522369A JP2001522369A (ja) 2001-11-13
JP2001522369A5 true JP2001522369A5 (https=) 2005-09-08
JP4514242B2 JP4514242B2 (ja) 2010-07-28

Family

ID=10811493

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54673298A Expired - Lifetime JP4514242B2 (ja) 1997-04-28 1998-04-27 抗ウイルスピリミジンヌクレオシド類似体

Country Status (13)

Country Link
US (1) US6573247B1 (https=)
EP (1) EP0980377B1 (https=)
JP (1) JP4514242B2 (https=)
AT (1) ATE221543T1 (https=)
AU (1) AU737902B2 (https=)
CA (1) CA2288147C (https=)
DE (1) DE69806919T2 (https=)
DK (1) DK0980377T3 (https=)
ES (1) ES2181208T3 (https=)
GB (1) GB9708611D0 (https=)
NZ (1) NZ500881A (https=)
PT (1) PT980377E (https=)
WO (1) WO1998049177A1 (https=)

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GB9708611D0 (en) * 1997-04-28 1997-06-18 Univ Cardiff Chemical compounds
GB9716231D0 (en) 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues
WO1999008110A1 (en) 1997-08-08 1999-02-18 Newbiotics, Inc. Methods and compositions for overcoming resistance to biologic and chemotherapy
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
IL137164A0 (en) 1998-01-23 2001-07-24 Newbiotics Inc Enzyme catalyzed therapeutic agents
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
BR0012676A (pt) 1999-07-22 2003-07-01 Newbiotics Inc Métodos para tratamento de tumores resistentes a terapia
GB0009486D0 (en) * 2000-04-17 2000-06-07 Univ Cardiff Chemical compounds
GB0011203D0 (en) * 2000-05-09 2000-06-28 Univ Cardiff Chemical compounds
AU2003225701A1 (en) 2002-03-08 2003-09-22 Glen Research Corporation Fluorescent nitrogenous base and nucleosides incorporating same
LT1576138T (lt) 2002-11-15 2017-06-26 Idenix Pharmaceuticals Llc 2`-šakoti nukleozidai derinyje su interferonu ir flaviviridae mutacija
GB0609178D0 (en) 2006-05-09 2006-06-21 Univ Cardiff Novel compounds
US20080261913A1 (en) 2006-12-28 2008-10-23 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of liver disorders
US9216979B2 (en) 2009-10-16 2015-12-22 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
WO2011047320A2 (en) 2009-10-16 2011-04-21 Rib-X Pharmaceuticals, Inc. Antimicrobial compounds and methods of making and using the same
KR101972992B1 (ko) * 2009-10-16 2019-04-29 멜린타 서브시디어리 코프. 항미생물성 화합물 및 이의 제조 방법 및 사용 방법
GB201016855D0 (en) * 2010-10-06 2010-11-17 Nucana Biomed Ltd Chemical compounds
US9243025B2 (en) 2011-03-31 2016-01-26 Idenix Pharmaceuticals, Llc Compounds and pharmaceutical compositions for the treatment of viral infections
KR20140065378A (ko) 2011-04-15 2014-05-29 멜린타 테라퓨틱스, 인크. 항미생물 화합물 및 그의 제조 방법과 사용 방법
GB201111779D0 (en) 2011-07-08 2011-08-24 Univ Cardiff Chemical compounds
AR088441A1 (es) 2011-09-12 2014-06-11 Idenix Pharmaceuticals Inc Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
US8507460B2 (en) 2011-10-14 2013-08-13 Idenix Pharmaceuticals, Inc. Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
JP6165848B2 (ja) 2012-05-22 2017-07-19 イデニク ファーマシューティカルズ エルエルシー 肝疾患のためのd−アミノ酸化合物
WO2013177188A1 (en) 2012-05-22 2013-11-28 Idenix Pharmaceuticals, Inc. 3',5'-cyclic phosphoramidate prodrugs for hcv infection
MX2014014323A (es) 2012-05-25 2015-02-12 Janssen R & D Ireland Nucleosidos de espirooxetano de uracilo.
WO2014052638A1 (en) 2012-09-27 2014-04-03 Idenix Pharmaceuticals, Inc. Esters and malonates of sate prodrugs
EP2906579B1 (en) 2012-10-08 2018-04-18 Idenix Pharmaceuticals LLC. 2'-chloro nucleoside analogs for hcv infection
US10723754B2 (en) 2012-10-22 2020-07-28 Idenix Pharmaceuticals Llc 2′,4′-bridged nucleosides for HCV infection
EP2935304A1 (en) 2012-12-19 2015-10-28 IDENIX Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
WO2014137930A1 (en) 2013-03-04 2014-09-12 Idenix Pharmaceuticals, Inc. Thiophosphate nucleosides for the treatment of hcv
WO2014137926A1 (en) 2013-03-04 2014-09-12 Idenix Pharmaceuticals, Inc. 3'-deoxy nucleosides for the treatment of hcv
WO2014160484A1 (en) 2013-03-13 2014-10-02 Idenix Pharmaceuticals, Inc. Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
EP2981542B1 (en) 2013-04-01 2021-09-15 Idenix Pharmaceuticals LLC 2',4'-fluoro nucleosides for the treatment of hcv
US10005779B2 (en) 2013-06-05 2018-06-26 Idenix Pharmaceuticals Llc 1′,4′-thio nucleosides for the treatment of HCV
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
EP3038623A4 (en) 2013-09-09 2017-04-19 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
KR20160070066A (ko) 2013-09-09 2016-06-17 멜린타 테라퓨틱스, 인크. 항균 화합물, 및 이의 제조 방법 및 이용 방법
US10202411B2 (en) 2014-04-16 2019-02-12 Idenix Pharmaceuticals Llc 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV
CA2979342A1 (en) 2015-03-11 2016-09-15 Melinta Therapeutics, Inc. Antimicrobial compounds and methods of making and using the same
WO2017193016A1 (en) 2016-05-06 2017-11-09 Melinta Therapeutics, Inc. Antimicrobials and methods of making and using same
EP4337646A4 (en) * 2021-05-13 2025-05-21 Promega Corporation BIOLUMINESCENT DETECTION OF DNA SYNTHESIS
US20260062437A1 (en) * 2022-08-26 2026-03-05 Regents Of The University Of Minnesota Antiviral compounds

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JPS62255499A (ja) * 1986-04-28 1987-11-07 Teijin Ltd 螢光性ヌクレオシド又はヌクレオチド
US5047519A (en) * 1986-07-02 1991-09-10 E. I. Du Pont De Nemours And Company Alkynylamino-nucleotides
GB9109186D0 (en) * 1991-04-29 1991-06-19 Wellcome Found Preparation of thionucleosides
YU43193A (sh) 1992-06-22 1997-01-08 Eli Lilly And Company 2'-deoksi-2',2'-difluoro(4-supstituisani)pirimidinski nukleozidi antivirusnog i antikancerogenog dejstva i međuproizvodi
JPH06192285A (ja) * 1992-12-25 1994-07-12 Yamasa Shoyu Co Ltd 1−(β−D−エリスロ−ペントフラン−2−ウロシル)ピリミジン誘導体の製造法
DE4321978A1 (de) * 1993-07-01 1995-01-12 Boehringer Mannheim Gmbh Liponucleotide von Desoxynucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
GB9505025D0 (en) 1995-03-13 1995-05-03 Medical Res Council Chemical compounds
GB9708611D0 (en) * 1997-04-28 1997-06-18 Univ Cardiff Chemical compounds
GB9716231D0 (en) * 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues
HK1053126A1 (zh) * 1999-07-22 2003-10-10 新生物生物公司 酶催化的治疗活化
BR0012676A (pt) * 1999-07-22 2003-07-01 Newbiotics Inc Métodos para tratamento de tumores resistentes a terapia
MXPA02000761A (es) * 1999-07-22 2002-08-12 Newbiotics Inc Agentes terapeuticos anti-infecciosos catalizados por enzima.

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