JP2001520012A5 - - Google Patents
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- Publication number
- JP2001520012A5 JP2001520012A5 JP2000516033A JP2000516033A JP2001520012A5 JP 2001520012 A5 JP2001520012 A5 JP 2001520012A5 JP 2000516033 A JP2000516033 A JP 2000516033A JP 2000516033 A JP2000516033 A JP 2000516033A JP 2001520012 A5 JP2001520012 A5 JP 2001520012A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- gene
- gene product
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000623 proteins and genes Proteins 0.000 description 36
- 108020004707 nucleic acids Proteins 0.000 description 30
- 102000039446 nucleic acids Human genes 0.000 description 30
- 150000007523 nucleic acids Chemical class 0.000 description 30
- 150000001875 compounds Chemical class 0.000 description 17
- 210000004027 cell Anatomy 0.000 description 14
- 238000000034 method Methods 0.000 description 12
- 208000036142 Viral infection Diseases 0.000 description 10
- 230000009385 viral infection Effects 0.000 description 10
- 239000002773 nucleotide Substances 0.000 description 9
- 125000003729 nucleotide group Chemical group 0.000 description 9
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 7
- 238000012216 screening Methods 0.000 description 7
- 230000002401 inhibitory effect Effects 0.000 description 6
- 230000001413 cellular effect Effects 0.000 description 4
- 230000003211 malignant effect Effects 0.000 description 4
- 108700008625 Reporter Genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 102100039436 DNA-binding protein inhibitor ID-3 Human genes 0.000 description 2
- 101710152064 DNA-binding protein inhibitor ID-3 Proteins 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000010076 replication Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 102100028505 6-pyruvoyl tetrahydrobiopterin synthase Human genes 0.000 description 1
- 108010045523 6-pyruvoyltetrahydropterin synthase Proteins 0.000 description 1
- 102100033350 ATP-dependent translocase ABCB1 Human genes 0.000 description 1
- 102100040269 Cleavage stimulation factor subunit 2 Human genes 0.000 description 1
- 101150051240 DLX2 gene Proteins 0.000 description 1
- 101000798869 Escherichia phage Mu DDE-recombinase A Proteins 0.000 description 1
- 101000891793 Homo sapiens Cleavage stimulation factor subunit 2 Proteins 0.000 description 1
- 101000795753 Homo sapiens mRNA decay activator protein ZFP36 Proteins 0.000 description 1
- 108010047230 Member 1 Subfamily B ATP Binding Cassette Transporter Proteins 0.000 description 1
- 102100026888 Mitogen-activated protein kinase kinase kinase 7 Human genes 0.000 description 1
- 102100030608 Mothers against decapentaplegic homolog 7 Human genes 0.000 description 1
- 101700026522 SMAD7 Proteins 0.000 description 1
- 108091023040 Transcription factor Proteins 0.000 description 1
- 102000040945 Transcription factor Human genes 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 108010070113 alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase I Proteins 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000002018 overexpression Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 108091008743 testicular receptors 4 Proteins 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6202197P | 1997-10-10 | 1997-10-10 | |
| US60/062,021 | 1997-10-10 | ||
| PCT/US1998/021276 WO1999019481A2 (en) | 1997-10-10 | 1998-10-08 | Mammalian genes involved in viral infection and tumor suppression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009033300A Division JP2009100780A (ja) | 1997-10-10 | 2009-02-16 | ウイルス感染および腫瘍抑制に関与する哺乳動物遺伝子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001520012A JP2001520012A (ja) | 2001-10-30 |
| JP2001520012A5 true JP2001520012A5 (enExample) | 2006-01-05 |
Family
ID=22039706
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000516033A Withdrawn JP2001520012A (ja) | 1997-10-10 | 1998-10-08 | ウイルス感染および腫瘍抑制に関与する哺乳動物遺伝子 |
| JP2009033300A Pending JP2009100780A (ja) | 1997-10-10 | 2009-02-16 | ウイルス感染および腫瘍抑制に関与する哺乳動物遺伝子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009033300A Pending JP2009100780A (ja) | 1997-10-10 | 2009-02-16 | ウイルス感染および腫瘍抑制に関与する哺乳動物遺伝子 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1021536A2 (enExample) |
| JP (2) | JP2001520012A (enExample) |
| AU (1) | AU9604198A (enExample) |
| CA (2) | CA2305312C (enExample) |
| WO (1) | WO1999019481A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001016323A2 (en) * | 1999-09-01 | 2001-03-08 | Subsidiary N0.3, Inc. | Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes |
| JP2002300900A (ja) * | 2001-04-05 | 2002-10-15 | National Institute Of Advanced Industrial & Technology | 腫瘍悪性化因子および腫瘍悪性化を抑制する化合物のスクリーニング方法 |
| WO2003002528A2 (en) * | 2001-06-29 | 2003-01-09 | Subsidiary No. 3 | Compositions and methods for inhibiting human immunodeficiency virus infection by down-regulating human cellular genes |
| EP1572084A4 (en) * | 2002-05-02 | 2008-04-30 | Univ Vanderbilt | MAMMALS WITH PARTICIPATION IN VIRUS INFECTION AND TUMORSUPPRESSION |
| EP2339009A1 (en) * | 2009-12-22 | 2011-06-29 | Sandoz Ag | Cold inducible promoter sequences |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU646799B2 (en) * | 1989-02-14 | 1994-03-10 | Amira, Inc. | Inhibiting transformation of cells having elevated purine metabolic enzyme activity |
| US5364783A (en) * | 1990-05-14 | 1994-11-15 | Massachusetts Institute Of Technology | Retrovirus promoter-trap vectors |
| US5350835A (en) * | 1991-11-05 | 1994-09-27 | Board Of Regents, University Of Texas | Cellular nucleic acid binding protein and uses thereof in regulating gene expression and in the treatment of aids |
| AU742243B2 (en) * | 1996-04-15 | 2001-12-20 | Vanderbilt University | Mammalian genes involved in viral infection and tumor suppression |
-
1998
- 1998-10-08 JP JP2000516033A patent/JP2001520012A/ja not_active Withdrawn
- 1998-10-08 CA CA2305312A patent/CA2305312C/en not_active Expired - Fee Related
- 1998-10-08 EP EP98949800A patent/EP1021536A2/en not_active Withdrawn
- 1998-10-08 CA CA2696653A patent/CA2696653A1/en not_active Abandoned
- 1998-10-08 AU AU96041/98A patent/AU9604198A/en not_active Abandoned
- 1998-10-08 WO PCT/US1998/021276 patent/WO1999019481A2/en not_active Ceased
-
2009
- 2009-02-16 JP JP2009033300A patent/JP2009100780A/ja active Pending
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