JP2001517212A5 - - Google Patents

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Publication number
JP2001517212A5
JP2001517212A5 JP1998537060A JP53706098A JP2001517212A5 JP 2001517212 A5 JP2001517212 A5 JP 2001517212A5 JP 1998537060 A JP1998537060 A JP 1998537060A JP 53706098 A JP53706098 A JP 53706098A JP 2001517212 A5 JP2001517212 A5 JP 2001517212A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1998537060A
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English (en)
Japanese (ja)
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JP4250771B2 (ja
JP2001517212A (ja
Filing date
Publication date
Priority claimed from AT0033897A external-priority patent/AT406373B/de
Application filed filed Critical
Publication of JP2001517212A publication Critical patent/JP2001517212A/ja
Publication of JP2001517212A5 publication Critical patent/JP2001517212A5/ja
Application granted granted Critical
Publication of JP4250771B2 publication Critical patent/JP4250771B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP53706098A 1997-02-27 1998-02-27 カチオン交換クロマトグラフィーによる因子VIII/vWF複合体の精製方法 Expired - Lifetime JP4250771B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0033897A AT406373B (de) 1997-02-27 1997-02-27 Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT338/97 1997-02-27
PCT/AT1998/000043 WO1998038220A1 (de) 1997-02-27 1998-02-27 Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie

Publications (3)

Publication Number Publication Date
JP2001517212A JP2001517212A (ja) 2001-10-02
JP2001517212A5 true JP2001517212A5 (https=) 2005-10-06
JP4250771B2 JP4250771B2 (ja) 2009-04-08

Family

ID=3487946

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53706098A Expired - Lifetime JP4250771B2 (ja) 1997-02-27 1998-02-27 カチオン交換クロマトグラフィーによる因子VIII/vWF複合体の精製方法

Country Status (11)

Country Link
US (3) US6831159B1 (https=)
EP (1) EP0971958B2 (https=)
JP (1) JP4250771B2 (https=)
AR (2) AR010121A1 (https=)
AT (2) AT406373B (https=)
AU (1) AU744919B2 (https=)
CA (1) CA2282841C (https=)
DE (1) DE59814211D1 (https=)
ES (1) ES2306471T5 (https=)
NO (2) NO324902B1 (https=)
WO (1) WO1998038220A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
EP1593388A1 (en) * 2004-05-05 2005-11-09 ZLB Behring GmbH Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers
US11197916B2 (en) 2007-12-28 2021-12-14 Takeda Pharmaceutical Company Limited Lyophilized recombinant VWF formulations
ES2298096B1 (es) 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
EP2349314B1 (en) 2008-10-21 2013-02-27 Baxter International Inc. Lyophilized recombinant vwf formulations
AU2010284116B9 (en) * 2009-08-20 2015-03-26 Takeda Pharmaceutical Company Limited Purification of VWF for increased removal of non-lipid enveloped viruses
KR101808751B1 (ko) 2009-11-13 2017-12-13 그리폴스 테라퓨틱스 인코포레이티드 폰 빌레브란트 인자(vWF)-함유 제제, 및 그와 관련된 방법, 키트 및 용도
KR101997543B1 (ko) * 2010-07-30 2019-07-09 이엠디 밀리포어 코포레이션 크로마토그래피 매질 및 방법
CA2821711C (en) 2010-12-15 2017-10-10 Baxter International Inc. Eluate collection using conductivity gradient
ES2682249T3 (es) * 2011-06-10 2018-09-19 Baxalta GmbH Tratamiento de una enfermedad de la coagulación mediante la administración de VWF recombinante
AU2012290004B2 (en) 2011-08-02 2014-11-27 Takeda Pharmaceutical Company Limited Systems and methods to increase protein yield from recombinant manufacturing processes
WO2013185184A2 (en) 2012-06-15 2013-12-19 Commonwealth Scientific And Industrial Research Organisation Production of long chain polyunsaturated fatty acids in plant cells
EP2925777B1 (en) * 2012-11-30 2019-05-01 Centre for Bioseparation Technology-VIT Monolith-based pseudo-bioaffinity purification methods for factor viii and applications thereof
AU2014346343B2 (en) 2013-11-08 2018-05-10 Csl Ltd. New method to concentrate von Willebrand factor or complexes thereof
EP3082405A4 (en) 2013-12-18 2017-12-13 Commonwealth Scientific and Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
SG11201610596PA (en) 2014-06-27 2017-01-27 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
ES2877563T3 (es) 2014-09-02 2021-11-17 Emd Millipore Corp Medios de cromotografía que comprenden conjuntos porosos discretos de nanofibrillas
US20170298091A1 (en) 2014-12-08 2017-10-19 Emd Millipore Corporation Mixed Bed Ion Exchange Adsorber
CA3069295A1 (en) 2017-07-07 2019-01-10 Baxalta Incorporated Treatment of gastrointestinal bleeding in patients with severe von willebrand disease by administration of recombinant vwf
US12128090B2 (en) 2019-02-01 2024-10-29 Takeda Pharmaceutical Company Limited Methods of prophylactic treatment using recombinant VWF (rVWF)
CN114106145B (zh) * 2021-10-22 2023-09-01 山东泰邦生物制品有限公司 一种血源人凝血因子ⅷ/血管性血友病因子复合物生产工艺

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
GB8403473D0 (en) * 1984-02-09 1984-03-14 Special Trustees For St Thomas Purification of factor viii
US5200510A (en) * 1987-06-16 1993-04-06 Zymogenetics, Inc. Method for purifying factor viii:c, von willebrand factor and complexes thereof
FR2651437A1 (fr) * 1989-09-05 1991-03-08 Lille Transfusion Sanguine Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.
NZ237244A (en) 1990-03-02 1992-10-28 Bio Technology General Corp Cloning and production of human von willebrand factor analogues and compositions thereof
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
IT1256622B (it) 1992-12-04 1995-12-12 Sclavo Spa Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii:c-fvw) da plasma umano totale.
AT401270B (de) 1994-09-26 1996-07-25 Immuno Ag Verfahren zur quantifizierung von genomischer dna
CA2159044A1 (en) * 1994-09-26 1996-03-27 Falko-Guenter Falkner Method of quantitating nucleic acids
DE4435485C1 (de) 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
DE4435392B4 (de) 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
CA2251558C (en) 1996-04-12 2005-11-22 Immuno Aktiengesellschaft Highly purified factor viii complex
AT403765B (de) 1996-04-12 1998-05-25 Immuno Ag Verfahren zur herstellung einer präparation enthaltend einen hochgereinigten komplex
AT405403B (de) 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie

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