JP2001516760A5 - - Google Patents
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- Publication number
- JP2001516760A5 JP2001516760A5 JP2000511769A JP2000511769A JP2001516760A5 JP 2001516760 A5 JP2001516760 A5 JP 2001516760A5 JP 2000511769 A JP2000511769 A JP 2000511769A JP 2000511769 A JP2000511769 A JP 2000511769A JP 2001516760 A5 JP2001516760 A5 JP 2001516760A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- substituted
- atoms
- unsubstituted
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 description 16
- 150000001875 compounds Chemical class 0.000 description 12
- 229910052760 oxygen Inorganic materials 0.000 description 12
- 125000003118 aryl group Chemical group 0.000 description 11
- 125000004432 carbon atom Chemical group C* 0.000 description 10
- 125000005843 halogen group Chemical group 0.000 description 8
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 8
- 125000003710 aryl alkyl group Chemical group 0.000 description 7
- 229910052757 nitrogen Inorganic materials 0.000 description 7
- 229910052698 phosphorus Inorganic materials 0.000 description 7
- 229910052717 sulfur Inorganic materials 0.000 description 7
- 229910052799 carbon Inorganic materials 0.000 description 6
- 125000004430 oxygen atom Chemical group O* 0.000 description 6
- 229910052710 silicon Inorganic materials 0.000 description 6
- 125000004434 sulfur atom Chemical group 0.000 description 6
- 125000000962 organic group Chemical group 0.000 description 5
- 125000003147 glycosyl group Chemical group 0.000 description 4
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 description 4
- -1 SO 3 − group Chemical group 0.000 description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 125000003545 alkoxy group Chemical group 0.000 description 2
- 125000003282 alkyl amino group Chemical group 0.000 description 2
- 125000004429 atom Chemical group 0.000 description 2
- GPTXWRGISTZRIO-UHFFFAOYSA-N chlorquinaldol Chemical compound ClC1=CC(Cl)=C(O)C2=NC(C)=CC=C21 GPTXWRGISTZRIO-UHFFFAOYSA-N 0.000 description 2
- 125000001072 heteroaryl group Chemical group 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 229910001413 alkali metal ion Inorganic materials 0.000 description 1
- 125000003342 alkenyl group Chemical group 0.000 description 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 description 1
- 125000004414 alkyl thio group Chemical group 0.000 description 1
- 125000000304 alkynyl group Chemical group 0.000 description 1
- 125000003277 amino group Chemical group 0.000 description 1
- 125000001769 aryl amino group Chemical group 0.000 description 1
- 125000005110 aryl thio group Chemical group 0.000 description 1
- 125000004104 aryloxy group Chemical group 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 125000002837 carbocyclic group Chemical group 0.000 description 1
- 125000004181 carboxyalkyl group Chemical group 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 125000004663 dialkyl amino group Chemical group 0.000 description 1
- 125000005842 heteroatom Chemical group 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
- 125000003107 substituted aryl group Chemical group 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 125000004665 trialkylsilyl group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92738197A | 1997-09-12 | 1997-09-12 | |
| US08/927,381 | 1997-09-12 | ||
| PCT/US1998/015734 WO1999014220A1 (en) | 1997-09-12 | 1998-08-12 | Novel compounds for generating chemiluminescence with a peroxidase |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001516760A JP2001516760A (ja) | 2001-10-02 |
| JP2001516760A5 true JP2001516760A5 (https=) | 2006-01-05 |
| JP4431272B2 JP4431272B2 (ja) | 2010-03-10 |
Family
ID=25454661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000511769A Expired - Lifetime JP4431272B2 (ja) | 1997-09-12 | 1998-08-12 | ペルオキシダーゼにより化学ルミネセンスを発生する新規化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6696569B2 (https=) |
| EP (1) | EP1015461B1 (https=) |
| JP (1) | JP4431272B2 (https=) |
| AT (1) | ATE266667T1 (https=) |
| AU (1) | AU9102398A (https=) |
| CA (1) | CA2300071C (https=) |
| DE (1) | DE69823845T2 (https=) |
| WO (1) | WO1999014220A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6017769A (en) * | 1998-06-17 | 2000-01-25 | Lumigen, Inc. | Non-enzymatic methods of generating chemiluminescence from acridan alkenes |
| AU5812299A (en) | 1999-09-07 | 2001-04-10 | Microvena Corporation | Retrievable septal defect closure device |
| WO2002000726A1 (en) * | 2000-06-26 | 2002-01-03 | Lumigen, Inc. | Electrochemiluminescence from acridan compounds |
| WO2003053934A1 (en) | 2001-12-20 | 2003-07-03 | Lumigen, Inc. | Improved compounds for generating chemiluminescence with a peroxidase |
| US6872828B2 (en) * | 2001-12-20 | 2005-03-29 | Lumigen, Inc. | Compounds for generating chemiluminescence with a peroxidase |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| AU2002311919B8 (en) | 2001-05-11 | 2007-03-22 | Ludwig Institute For Cancer Research Ltd | Specific binding proteins and uses thereof |
| US7560556B2 (en) * | 2001-12-20 | 2009-07-14 | Lumigen, Inc. | Assay methods using chemiluminescent detection of peroxidase |
| US6897036B2 (en) | 2002-06-06 | 2005-05-24 | Lumigen, Inc. | Fluorescent detection of peroxidase enzymes |
| US7422868B2 (en) * | 2004-07-02 | 2008-09-09 | Promega Corporation | Microbial ATP extraction and detection system |
| US7879575B2 (en) * | 2005-04-27 | 2011-02-01 | The Trustees Of The University Of Pennsylvania | Nanostructures that provide a modified nanoenvironment for the enhancement of luminescence |
| WO2006116686A2 (en) * | 2005-04-27 | 2006-11-02 | The Trustees Of The University Of Pennsylvania | Nanostructure enhanced luminescent devices |
| US20090246888A1 (en) * | 2005-04-27 | 2009-10-01 | The Trustees Of The University Of Pennsylvania | Nanoassays |
| WO2007082899A1 (en) | 2006-01-17 | 2007-07-26 | Vib Vzw | Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration |
| US7799534B2 (en) | 2006-05-09 | 2010-09-21 | Beckman Coulter, Inc. | Nonseparation assay methods |
| US7732153B2 (en) | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
| CA2664327A1 (en) * | 2006-09-15 | 2008-03-20 | Lifescience Pharmaceuticals | Method for detecting and treating skin disorders |
| WO2008055924A1 (en) | 2006-11-07 | 2008-05-15 | Vib Vzw | Diagnosis and treatment of t-cell acute lymphoblastic leukemia |
| US20100240070A1 (en) * | 2007-11-07 | 2010-09-23 | Beckman Coulter, Inc. | Nonseparation Assay Methods Using Peroxide Generating Enzymes |
| PL2401392T3 (pl) | 2009-02-27 | 2017-08-31 | Beckman Coulter, Inc. | Homogeniczne oznaczenia fazy roztworu |
| CN102333885A (zh) | 2009-02-27 | 2012-01-25 | 贝克曼考尔特公司 | 使用选择性信号抑制剂的非分离式测定 |
| US20110097723A1 (en) * | 2009-09-19 | 2011-04-28 | Qun Liu | Methods and reagents for analyte detection |
| WO2013078109A1 (en) | 2011-11-21 | 2013-05-30 | The Procter & Gamble Company | Absorbent articles with improved absorption properties |
| EP2535027B1 (en) | 2011-06-17 | 2022-08-17 | The Procter & Gamble Company | Absorbent article having improved absorption properties |
| CN104761584A (zh) * | 2015-02-27 | 2015-07-08 | 北京利德曼生化股份有限公司 | 吖啶酯衍生物及其合成方法和应用 |
| WO2020012391A1 (en) | 2018-07-13 | 2020-01-16 | 3M Innovative Properties Company | Assay |
| CN112400113B (zh) | 2018-07-13 | 2022-04-15 | 3M创新有限公司 | 特异性结合化学发光测定法 |
| CN115433229B (zh) * | 2022-08-29 | 2025-07-25 | 长沙创新药物工业技术研究院有限公司 | 一种化学发光底物的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1327361C (en) * | 1988-01-14 | 1994-03-01 | Nihon Nohyaku Co., Ltd. | Ketenedithioacetal derivative and processes for producing the same as well as a composition containing the same |
| DE68911633T2 (de) * | 1988-09-30 | 1994-04-07 | Fujirebio Kk | Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz. |
| EP0422252B1 (en) * | 1989-04-28 | 1995-07-26 | Toray Industries, Inc. | Method for detecting a substance using chemiluminescence |
| US5324835A (en) * | 1990-03-30 | 1994-06-28 | Biosensor Laboratories Co., Ltd. | Pyridazinoquinoxalinones for use as chemiluminescent agents |
| US5491072A (en) * | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| US5648484A (en) * | 1995-03-07 | 1997-07-15 | Schering Corporation | Catalytic enantioselective synthesis of a spriofused azetidinone |
| CN1173954C (zh) * | 1996-01-16 | 2004-11-03 | 鲁米根公司 | 与磷酸酶反应产生化学发光的化合物、组合物和方法 |
| US6126870A (en) * | 1997-09-12 | 2000-10-03 | Lumigen, Inc. | Chemiluminescent labeling compounds |
-
1998
- 1998-08-12 AU AU91023/98A patent/AU9102398A/en not_active Abandoned
- 1998-08-12 EP EP98943173A patent/EP1015461B1/en not_active Expired - Lifetime
- 1998-08-12 AT AT98943173T patent/ATE266667T1/de not_active IP Right Cessation
- 1998-08-12 JP JP2000511769A patent/JP4431272B2/ja not_active Expired - Lifetime
- 1998-08-12 CA CA002300071A patent/CA2300071C/en not_active Expired - Lifetime
- 1998-08-12 WO PCT/US1998/015734 patent/WO1999014220A1/en not_active Ceased
- 1998-08-12 DE DE69823845T patent/DE69823845T2/de not_active Expired - Lifetime
-
2001
- 2001-04-11 US US09/833,050 patent/US6696569B2/en not_active Expired - Lifetime
-
2004
- 2004-01-09 US US10/754,750 patent/US6891057B2/en not_active Expired - Lifetime
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