JP2001515505A - 軸索再生を促進する単核貪食細胞及びその使用 - Google Patents
軸索再生を促進する単核貪食細胞及びその使用Info
- Publication number
- JP2001515505A JP2001515505A JP54028998A JP54028998A JP2001515505A JP 2001515505 A JP2001515505 A JP 2001515505A JP 54028998 A JP54028998 A JP 54028998A JP 54028998 A JP54028998 A JP 54028998A JP 2001515505 A JP2001515505 A JP 2001515505A
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- cells
- mononuclear
- mononuclear phagocytic
- phagocytic cells
- monocytes
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/17—Monocytes; Macrophages
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/414—Nervous system antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/08—Coculture with; Conditioned medium produced by cells of the nervous system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/818,818 | 1997-03-14 | ||
| US08/818,818 US6117424A (en) | 1995-09-15 | 1997-03-14 | Compositions of mononuclear phagocytes useful for promoting axonal regeneration |
| US09/041,280 US6267955B1 (en) | 1995-09-15 | 1998-03-11 | Mononuclear phagocytes and their use to promote axonal regeneration |
| US09/041,280 | 1998-03-11 | ||
| PCT/IL1998/000120 WO1998041220A1 (en) | 1997-03-14 | 1998-03-13 | Mononuclear phagocytes and their use to promote axonal regeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001515505A true JP2001515505A (ja) | 2001-09-18 |
| JP2001515505A5 JP2001515505A5 (https=) | 2005-11-10 |
Family
ID=26717980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54028998A Ceased JP2001515505A (ja) | 1997-03-14 | 1998-03-13 | 軸索再生を促進する単核貪食細胞及びその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6267955B1 (https=) |
| EP (1) | EP0966292A1 (https=) |
| JP (1) | JP2001515505A (https=) |
| AU (1) | AU731086B2 (https=) |
| CA (1) | CA2283891A1 (https=) |
| IL (1) | IL131888A0 (https=) |
| NZ (1) | NZ337813A (https=) |
| WO (1) | WO1998041220A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006523199A (ja) * | 2003-03-28 | 2006-10-12 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 末梢神経疾患の治療及び／又は予防のためのクラステリンの使用 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2785135B1 (fr) | 1998-10-22 | 2000-12-29 | Sfr Sa | Procede de lancement d'une application par un terminal, sous commande d'un module d'identification d'abonne, module d'identification d'abonne et terminal correspondants |
| US20040120891A1 (en) | 1998-12-21 | 2004-06-24 | Craig Hill | Compounds for intracellular delivery of therapeutic moieties to nerve cells |
| US6652864B1 (en) | 1998-12-21 | 2003-11-25 | Asilomar Pharmaceuticals, Inc. | Compounds for intracellular delivery of therapeutic moieties to nerve cells |
| ATE422901T1 (de) * | 2001-03-12 | 2009-03-15 | Inst Of Gene And Brain Science | Granulocyte-macrophage colony-stimulating factor (gm-csf) als heilmittel für nervenschäden |
| AU2002309987A1 (en) * | 2001-05-25 | 2002-12-09 | Hill-Rom Services, Inc. | Modular patient room |
| AU2002353465B2 (en) | 2001-11-21 | 2008-10-16 | Yeda Research And Development Co. Ltd. | Process for the manufacture of human mononuclear phagocytic leukocytes |
| WO2003105750A2 (en) * | 2002-06-14 | 2003-12-24 | Yeda Research And Development Co. Ltd | Antigen-presenting cells for neuroprotection and nerve regeneration |
| AU2003259846A1 (en) * | 2002-08-16 | 2004-03-03 | The General Hospital Corporation | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US20090010873A1 (en) * | 2004-11-29 | 2009-01-08 | Yeda Research And Development Co. Ltd. | Methods of Cell Therapy, Neurogenesis and Oligodendrogenesis |
| LT3028716T (lt) | 2006-10-10 | 2020-12-10 | Regenesance B.V. | Komplemento slopinimas nervų regeneracijos pagerinimui |
| BRPI0919020B8 (pt) * | 2008-09-12 | 2021-05-25 | Cryopraxis Criobiologia Ltda | uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris |
| EP2370112B1 (en) | 2008-11-24 | 2017-04-05 | Bonus Cellora Ltd. | Implantable liposome embedded matrix composition, and uses thereof |
| CN105377273A (zh) | 2013-05-22 | 2016-03-02 | 耶达研究与发展公司 | 用于治疗眼睛疾病或病症的人类单核细胞亚群 |
| JP6963555B2 (ja) * | 2016-09-02 | 2021-11-10 | タカラバイオ株式会社 | 多能性幹細胞からミクログリアを得る方法 |
| US11897928B2 (en) | 2018-07-18 | 2024-02-13 | Manzanita Pharmaceuticals, Inc. | Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof |
| CA3254900A1 (en) * | 2022-03-30 | 2023-10-05 | Mdx Management Llc | COMPOSITIONS AND METHODS FOR ACTIVATING IMMUNE CELLS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5157024A (en) | 1977-10-16 | 1992-10-20 | Strategic Medical Research Corporation | Method of enhancing the activity of phagocytes including macrophages, modulating the cellular or humoral immune response, and reducing the adverse effects of stress in warm blooded animals |
| IL71440A0 (en) | 1984-04-04 | 1984-07-31 | Univ Ramot | Composition for nerve regeneration |
| US5078996A (en) | 1985-08-16 | 1992-01-07 | Immunex Corporation | Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor |
| US5082670A (en) | 1988-12-15 | 1992-01-21 | The Regents Of The University Of California | Method of grafting genetically modified cells to treat defects, disease or damage or the central nervous system |
| IL97365A0 (en) | 1991-02-27 | 1992-05-25 | Yeda Res & Dev | Pharmaceutical compositions comprising a lymphokine |
| IL91459A0 (en) | 1989-08-28 | 1990-04-29 | Yeda Res & Dev | Oligodendrocyte inhibitory factor |
| US5800812A (en) | 1995-09-15 | 1998-09-01 | Yeda Research And Development Co. Ltd. | Methods of use of mononuclear phagocytes to promote axonal regeneration |
| IL116922A0 (en) | 1996-01-26 | 1996-05-14 | Yeda Res & Dev | Compositions for the regeneration of nerves in the central nervous system |
-
1998
- 1998-03-11 US US09/041,280 patent/US6267955B1/en not_active Expired - Lifetime
- 1998-03-13 AU AU66343/98A patent/AU731086B2/en not_active Ceased
- 1998-03-13 NZ NZ337813A patent/NZ337813A/en unknown
- 1998-03-13 WO PCT/IL1998/000120 patent/WO1998041220A1/en not_active Ceased
- 1998-03-13 EP EP98908268A patent/EP0966292A1/en not_active Withdrawn
- 1998-03-13 IL IL13188898A patent/IL131888A0/xx unknown
- 1998-03-13 CA CA002283891A patent/CA2283891A1/en not_active Abandoned
- 1998-03-13 JP JP54028998A patent/JP2001515505A/ja not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006523199A (ja) * | 2003-03-28 | 2006-10-12 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 末梢神経疾患の治療及び／又は予防のためのクラステリンの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2283891A1 (en) | 1998-09-24 |
| AU6634398A (en) | 1998-10-12 |
| IL131888A0 (en) | 2001-03-19 |
| AU731086B2 (en) | 2001-03-22 |
| US6267955B1 (en) | 2001-07-31 |
| EP0966292A1 (en) | 1999-12-29 |
| NZ337813A (en) | 2002-04-26 |
| WO1998041220A1 (en) | 1998-09-24 |
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