JP2001512965A5 - - Google Patents

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Publication number
JP2001512965A5
JP2001512965A5 JP1998533032A JP53303298A JP2001512965A5 JP 2001512965 A5 JP2001512965 A5 JP 2001512965A5 JP 1998533032 A JP1998533032 A JP 1998533032A JP 53303298 A JP53303298 A JP 53303298A JP 2001512965 A5 JP2001512965 A5 JP 2001512965A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998533032A
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English (en)
Japanese (ja)
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JP4126097B2 (ja
JP2001512965A (ja
Filing date
Publication date
Priority claimed from US08/792,283 external-priority patent/US5804183A/en
Application filed filed Critical
Publication of JP2001512965A publication Critical patent/JP2001512965A/ja
Publication of JP2001512965A5 publication Critical patent/JP2001512965A5/ja
Application granted granted Critical
Publication of JP4126097B2 publication Critical patent/JP4126097B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP53303298A 1997-01-31 1998-01-27 Mycoplasma arthritidis由来アルギニンデイミナーゼ及びそれを含むポリマーコンジュゲート Expired - Fee Related JP4126097B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/792,283 1997-01-31
US08/792,283 US5804183A (en) 1997-01-31 1997-01-31 Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
PCT/US1998/001635 WO1998033519A1 (en) 1997-01-31 1998-01-27 Arginine deiminase derived from mycoplasma arthritidis and polymer conjugates containing the same

Publications (3)

Publication Number Publication Date
JP2001512965A JP2001512965A (ja) 2001-08-28
JP2001512965A5 true JP2001512965A5 (enExample) 2005-07-14
JP4126097B2 JP4126097B2 (ja) 2008-07-30

Family

ID=25156365

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53303298A Expired - Fee Related JP4126097B2 (ja) 1997-01-31 1998-01-27 Mycoplasma arthritidis由来アルギニンデイミナーゼ及びそれを含むポリマーコンジュゲート

Country Status (9)

Country Link
US (3) US5804183A (enExample)
EP (1) EP1011717B1 (enExample)
JP (1) JP4126097B2 (enExample)
AT (1) ATE314086T1 (enExample)
AU (1) AU6047598A (enExample)
DE (1) DE69832993T2 (enExample)
DK (1) DK1011717T3 (enExample)
ES (1) ES2255147T3 (enExample)
WO (1) WO1998033519A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183738B1 (en) * 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
US6635462B1 (en) * 1997-05-12 2003-10-21 Phoenix Pharmacologies, Inc. Mutated form of arginine deiminase
EP1337630A2 (en) * 2000-11-28 2003-08-27 Phoenix Pharmacologics, Inc. Modified arginine deiminase
US6645739B2 (en) * 2001-07-26 2003-11-11 Phoenix Pharmacologies, Inc. Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
US8129330B2 (en) 2002-09-30 2012-03-06 Mountain View Pharmaceuticals, Inc. Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
US20040062748A1 (en) * 2002-09-30 2004-04-01 Mountain View Pharmaceuticals, Inc. Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
CA2506244C (en) * 2002-11-18 2012-10-30 Phoenix Pharmacologics, Inc. Methods for inhibiting viral replication in vivo
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
WO2007130453A2 (en) 2006-05-02 2007-11-15 Allozyne, Inc. Non-natural amino acid substituted polypeptides
US20080096819A1 (en) * 2006-05-02 2008-04-24 Allozyne, Inc. Amino acid substituted molecules
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
CA2707840A1 (en) * 2007-08-20 2009-02-26 Allozyne, Inc. Amino acid substituted molecules
JP2009044997A (ja) * 2007-08-20 2009-03-05 Sony Corp ビリルビンオキシダーゼ(bod)の被覆方法
EP2295560A1 (en) 2009-09-14 2011-03-16 RWTH Aachen University Directed evolution of arginine deiminase for increased activity at physiological pH
USRE48805E1 (en) 2013-03-06 2021-11-02 Vision Global Holdings Ltd. Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
EP3744341A1 (en) 2013-03-15 2020-12-02 TDW Group Arginine deiminase with reduced cross-reactivity toward adi - peg 20 antibodies for cancer treatment
KR102523031B1 (ko) * 2014-03-18 2023-04-19 티디더블유 그룹 조작된 키메라성 페길화된 adi 및 사용 방법
AU2015317848B2 (en) 2014-09-16 2021-04-22 Polaris Group Arginine deiminase with reduced cross-reactivity toward ADI - PEG 20 antibodies for cancer treatment
US11613759B2 (en) 2015-09-04 2023-03-28 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
JP7602702B2 (ja) 2016-05-03 2024-12-19 ステムセル テクノロジーズ カナダ インコーポレーテッド 寛容性を誘導するための生体分子の細胞内送達
TWI847958B (zh) 2016-07-05 2024-07-11 英屬開曼群島商北極星藥業集團股份有限公司 用精胺酸耗盡劑進行之組合癌症免疫療法
EP3534963B1 (en) 2016-11-02 2024-04-17 Polaris Group Formulations of pegylated arginine deiminase
CN116143678A (zh) 2016-11-14 2023-05-23 杭州多禧生物科技有限公司 偶联连接体,含有此连接体的细胞结合分子-药物偶联物及其制备和应用
US12344645B2 (en) 2017-03-29 2025-07-01 Polaris Group Protein conjugates
WO2019042628A1 (en) 2017-08-31 2019-03-07 Erytech Pharma ARGININE DEIMINASE ENCAPSULATED WITHIN ERYTHROCYTES AND THEIR USE IN THE TREATMENT OF CANCER AND ARGINASE-1 DEFICIENCY
EP3449935A1 (en) 2017-08-31 2019-03-06 Erytech Pharma Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
EP4007768A4 (en) * 2019-08-01 2023-11-15 The University of North Carolina at Chapel Hill COMPOSITIONS AND METHODS FOR BINDING ANTIBODIES AND INHIBITING NEUTRALIZING ANTIBODIES
CA3128035A1 (en) 2020-08-13 2022-02-13 Bioasis Technologies, Inc. Combination therapies for delivery across the blood brain barrier
US20240309055A1 (en) * 2021-02-03 2024-09-19 The University Of North Carolina At Chapel Hill Protein m analogs and fusion proteins and their use for inhibiting antibody function
WO2022078524A2 (en) 2021-11-03 2022-04-21 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPH0253490A (ja) * 1988-08-16 1990-02-22 Agency Of Ind Science & Technol アルギニン・デイミナーゼ遺伝子
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
JP2900279B2 (ja) * 1989-08-02 1999-06-02 株式会社ジャパンエナジー 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤
JP3209338B2 (ja) * 1990-09-10 2001-09-17 株式会社ジャパンエナジー ポリエチレングリコール修飾アルギニンデイミナーゼおよびその製造法
US5372942A (en) * 1992-02-10 1994-12-13 Coriell Institute For Medical Research Protease K resistant arginine deiminase, its method of preparation and its use as an anti-neoplastic agent
US5349001A (en) * 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same

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