JP2001511187A - 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス - Google Patents

選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス

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Publication number
JP2001511187A
JP2001511187A JP53778198A JP53778198A JP2001511187A JP 2001511187 A JP2001511187 A JP 2001511187A JP 53778198 A JP53778198 A JP 53778198A JP 53778198 A JP53778198 A JP 53778198A JP 2001511187 A JP2001511187 A JP 2001511187A
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Japan
Prior art keywords
cells
subject
rats
sidr
immune
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JP53778198A
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English (en)
Japanese (ja)
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JP2001511187A5 (https=
Inventor
ロイ―チャウダリー,ジャヤンタ
イラン,ヤロン
ラバーニ,エレザー
エル. エンゲルハート,ディーン
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エンゾー セラピュウティクス, インコーポレイテッド
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Publication of JP2001511187A publication Critical patent/JP2001511187A/ja
Publication of JP2001511187A5 publication Critical patent/JP2001511187A5/ja
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/001Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP53778198A 1997-02-28 1998-02-26 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス Pending JP2001511187A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80862997A 1997-02-28 1997-02-28
US08/808,629 1997-02-28
PCT/US1998/003606 WO1998037917A1 (en) 1997-02-28 1998-02-26 Novel processes implementing selective immune down regulation (sidr)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007062690A Division JP2007145871A (ja) 1997-02-28 2007-03-12 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス

Publications (2)

Publication Number Publication Date
JP2001511187A true JP2001511187A (ja) 2001-08-07
JP2001511187A5 JP2001511187A5 (https=) 2004-10-28

Family

ID=25199306

Family Applications (3)

Application Number Title Priority Date Filing Date
JP53778198A Pending JP2001511187A (ja) 1997-02-28 1998-02-26 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス
JP2007062690A Withdrawn JP2007145871A (ja) 1997-02-28 2007-03-12 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス
JP2010276299A Withdrawn JP2011046753A (ja) 1997-02-28 2010-12-10 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007062690A Withdrawn JP2007145871A (ja) 1997-02-28 2007-03-12 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス
JP2010276299A Withdrawn JP2011046753A (ja) 1997-02-28 2010-12-10 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス

Country Status (6)

Country Link
US (2) US20040022768A1 (https=)
EP (2) EP0914163B1 (https=)
JP (3) JP2001511187A (https=)
CA (1) CA2252790A1 (https=)
IL (3) IL126714A (https=)
WO (1) WO1998037917A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001511187A (ja) * 1997-02-28 2001-08-07 エンゾー セラピュウティクス, インコーポレイテッド 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス
EP1005561A4 (en) 1997-03-21 2004-03-31 Enzo Therapeutics Inc A Fully VECTOR, VIRAL VECTORS AND PACKAGING CELL LINES TO THEIR REPRODUCTION
US8703480B1 (en) 1997-03-21 2014-04-22 Enzo Therapeutics, Inc. Biological function effecting viral vectors and chimeric cells useful as packaging cell lines and target cells
CA2313899A1 (en) * 1999-07-16 2001-01-16 Enzo Therapeutics, Inc. Novel selective imune down regulation (sidr) mediated transplantation processes, processes for preventing or treating diseases in a subject, and compositions of matter comprising trained or programmed cells, tissues or organs useful for sidr establishment
IL142802A (en) 2000-04-27 2015-01-29 Enzo Therapeutics Inc Use of one or more HBV antigens for the preparation of oral pharmaceutical preparations for the treatment of a person with active HBV infection or hepatocellular carcinoma
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)
US7485314B2 (en) * 2002-05-06 2009-02-03 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Induction of antigen specific immunologic tolerance
WO2005032462A2 (en) 2003-02-27 2005-04-14 Enzo Therapeutics, Inc. Glucocerebroside treatment of disease
US20070184058A1 (en) * 2003-02-27 2007-08-09 Yaron Ilan Glucocerebroside treatment of pulmonary or respiratory diseases or disorders
US20040171522A1 (en) * 2003-02-27 2004-09-02 Yaron Ilan Regulation of immune responses by manipulation of intermediary metabolite levels
US9717754B2 (en) 2003-02-27 2017-08-01 Enzo Therapeutics, Inc. Glucocerebroside treatment of disease
US20050069546A1 (en) 2003-09-30 2005-03-31 Yaron Ilan Educated NKT cells and their uses in the treatment of immune-related disorders
US7364758B2 (en) * 2004-08-31 2008-04-29 Shih-Lan Hsu Pharmaceutical use of Graptopetalum and related plants
US7588776B2 (en) 2004-08-31 2009-09-15 Shih-Lan Hsu Pharmaceutical use of water-soluble fraction of Graptopetalum
BRPI0915582A2 (pt) * 2008-06-06 2016-01-26 Baylor Res Inst anticorpos anto-cd8 que bloqueiam a sensibilização de efetores citotóxicos e levam à geração de células t cd8+ reguladoras
DE102015225578A1 (de) * 2015-12-17 2017-06-22 Robert Bosch Gmbh Vorrichtung zum Empfangen von Mikrowellenstrahlung
TW201911653A (zh) * 2017-08-03 2019-03-16 廣達電腦股份有限公司 雙頻帶天線結構
CN109355300B (zh) * 2018-11-26 2022-01-28 成都中医药大学 黄连sdir转录因子在提高植物抗旱中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322405A (en) * 1981-04-06 1982-03-30 Laboratoires Om Societe Anonyme Method for treating rheumatoid arthritis
US4950469A (en) * 1986-05-30 1990-08-21 La Jolla Pharmaceutical Company D-GL conjugate therapy
US5399347A (en) * 1987-06-24 1995-03-21 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
DE69033975T2 (de) * 1989-01-23 2002-10-02 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Rekombinanttherapien für Infektionen und hyperproliferative Störungen
ES2085983T3 (es) * 1989-12-20 1996-06-16 Schering Corp Antagonistas de anticuerpos de la interleuquina-4 humana.
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
IL99864A (en) * 1990-10-31 2000-11-21 Autoimmune Inc Compositions for suppressing transplant rejection in mammals which contain tissue donor derived MHC antigens
WO1994003202A1 (en) * 1992-08-10 1994-02-17 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Interleukin-4 stimulated t lymphocyte cell death
PT1438970E (pt) * 1993-03-19 2008-12-26 D Allen Allen Métodos para inibição de doença associada ao vih que utilizam anticorpos monoclonais dirigidos contra células t citotóxicas anti-próprias
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
EP0752880A4 (en) * 1994-04-08 2000-08-09 Brigham & Womens Hospital TREATMENT OF AUTOIMMUNE DISEASES BY ORAL TOLERATION AND / OR INTERFERON OF TYPE I
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US5849285A (en) * 1994-04-13 1998-12-15 Research Corporation Technologies, Inc. Autoimmune disease treatment with sertoli cells and in vitro co-culture of mammal cells with sertoli cells
US5872154A (en) * 1995-02-24 1999-02-16 The Trustees Of The University Of Pennsylvania Method of reducing an immune response to a recombinant adenovirus
JP2001511187A (ja) * 1997-02-28 2001-08-07 エンゾー セラピュウティクス, インコーポレイテッド 選択的免疫ダウンレギュレーション(sidr)を行う新規プロセス
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)

Also Published As

Publication number Publication date
JP2007145871A (ja) 2007-06-14
WO1998037917A1 (en) 1998-09-03
EP2301567A1 (en) 2011-03-30
EP0914163B1 (en) 2016-02-24
US20040022768A1 (en) 2004-02-05
IL126714A (en) 2010-12-30
EP0914163A1 (en) 1999-05-12
EP0914163A4 (en) 2001-08-16
IL126714A0 (en) 1999-08-17
JP2011046753A (ja) 2011-03-10
US20040023909A1 (en) 2004-02-05
IL184691A0 (en) 2007-12-03
CA2252790A1 (en) 1998-09-03
IL209847A0 (en) 2011-02-28

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