JP2001508430A5 - - Google Patents

Download PDF

Info

Publication number
JP2001508430A5
JP2001508430A5 JP1998530400A JP53040098A JP2001508430A5 JP 2001508430 A5 JP2001508430 A5 JP 2001508430A5 JP 1998530400 A JP1998530400 A JP 1998530400A JP 53040098 A JP53040098 A JP 53040098A JP 2001508430 A5 JP2001508430 A5 JP 2001508430A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998530400A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001508430A (ja
Filing date
Publication date
Priority claimed from US08/779,767 external-priority patent/US6737057B1/en
Application filed filed Critical
Publication of JP2001508430A publication Critical patent/JP2001508430A/ja
Publication of JP2001508430A5 publication Critical patent/JP2001508430A5/ja
Ceased legal-status Critical Current

Links

JP53040098A 1997-01-07 1998-01-07 免疫抑制因子のエンドサイトーシスによる提示のための化合物、組成物及び方法 Ceased JP2001508430A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/779,767 1997-01-07
US08/779,767 US6737057B1 (en) 1997-01-07 1997-01-07 Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
PCT/US1998/000520 WO1998030706A1 (en) 1997-01-07 1998-01-07 Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors

Publications (2)

Publication Number Publication Date
JP2001508430A JP2001508430A (ja) 2001-06-26
JP2001508430A5 true JP2001508430A5 (OSRAM) 2005-09-08

Family

ID=25117492

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53040098A Ceased JP2001508430A (ja) 1997-01-07 1998-01-07 免疫抑制因子のエンドサイトーシスによる提示のための化合物、組成物及び方法

Country Status (6)

Country Link
US (2) US6737057B1 (OSRAM)
EP (1) EP1012308A1 (OSRAM)
JP (1) JP2001508430A (OSRAM)
AU (1) AU744885B2 (OSRAM)
CA (1) CA2277582A1 (OSRAM)
WO (1) WO1998030706A1 (OSRAM)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020081298A1 (en) * 1997-01-07 2002-06-27 Habib Zaghouani Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
PT1037927E (pt) 1997-12-08 2004-10-29 Emd Lexigen Res Ct Corp Proteinas de fusao heterodimericas uteis para imunoterapia de abordagem selectiva e estimulacao imunologica geral
AU5090899A (en) * 1998-07-06 2000-01-24 University Of Tennessee Research Corporation, The Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
EP1104456A1 (en) * 1998-08-10 2001-06-06 Chiron Corporation Engineered antigen-presenting cells expressing an array of antigens and uses thereof
SK782002A3 (en) * 1999-07-21 2003-08-05 Lexigen Pharm Corp FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
US7067110B1 (en) 1999-07-21 2006-06-27 Emd Lexigen Research Center Corp. Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
BR0013231A (pt) 1999-08-09 2002-07-23 Lexigen Pharm Corp Complexos citocina-anticorpo múltiplos
EP1598370A3 (en) * 1999-10-27 2006-05-10 Cel-Sci Corporation Methods of preparation and composition of peptide constructs useful for treatment of autoimmune and transplant related host versus graft conditions
JP2003514828A (ja) * 1999-10-27 2003-04-22 セル−サイ・コーポレーシヨン 自己免疫および移植組織に関連する宿主対移植片症状の処置に有用なペプチド構築物の調製法および組成物
EP1228214A2 (en) 1999-11-12 2002-08-07 MERCK PATENT GmbH Erythropoietin forms with improved properties
JP5179689B2 (ja) 2000-02-11 2013-04-10 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗体ベース融合タンパク質の循環系内半減期の増強
DE60123238T2 (de) * 2000-06-05 2007-05-03 University of Tennessee Corp., Knoxville Zusammensetzungen zur behandlung von autoimmunkrankheiten
JP5390055B2 (ja) 2000-06-29 2014-01-15 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 免疫サイトカインの取り込み増強剤との併用治療による抗体−サイトカイン融合タンパク質媒介免疫応答の増強
HUP0303428A2 (hu) 2001-03-07 2004-01-28 Merck Patent Gmbh. Expressziós eljárás hibrid izotípusú antitestcsoportot tartalmazó fehérjékhez
WO2002079415A2 (en) 2001-03-30 2002-10-10 Lexigen Pharmaceuticals Corp. Reducing the immunogenicity of fusion proteins
KR100900166B1 (ko) 2001-05-03 2009-06-02 메르크 파텐트 게엠베하 재조합 종양 특이적 항체 및 이들의 용도
ATE542137T1 (de) 2001-12-04 2012-02-15 Merck Patent Gmbh Immunocytokine mit modulierter selektivität
US8603472B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide
ATE382367T1 (de) 2002-04-09 2008-01-15 Univ Missouri Behandlung des typ 1 diabetes vor und nach expression von prädispositionsmarkern
US8603471B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions for preventing the onset of type 1 diabetes
US8609091B2 (en) 2002-04-09 2013-12-17 The Curators Of The University Of Missouri Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes
US7744876B2 (en) 2002-04-09 2010-06-29 The Curators Of The University Of Missouri Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes
WO2003099312A1 (en) * 2002-05-27 2003-12-04 Östergötlands Läns Landsting Method for determining immune system affecting compounds
CN100432105C (zh) 2002-12-17 2008-11-12 默克专利有限公司 与gd2结合的小鼠14.18抗体的人源化抗体(h14.18)以及其与il-2的融合
PT1699822E (pt) 2003-12-30 2008-07-30 Merck Patent Gmbh Proteínas de fusão de il-7
BRPI0417916A (pt) 2003-12-31 2007-04-10 Merck Patent Gmbh proteìna de fusão de fc-eritropoietina com farmacocinética melhorada
AU2005203962C1 (en) 2004-01-05 2012-11-08 Antisoma Research Limited Interleukin-12 targeted to oncofoetal fibronectin
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
RU2437893C2 (ru) 2004-12-09 2011-12-27 Мерк Патент Гмбх Варианты il-7 со сниженной иммуногенностью
WO2006110091A1 (en) * 2005-04-15 2006-10-19 Therim Diagnostica Ab Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
WO2008136736A2 (en) 2007-05-08 2008-11-13 Canimguide Therapeutics Ab Immunoregulatory structures from normally occurring proteins
SG175233A1 (en) 2009-04-22 2011-11-28 Merck Patent Gmbh Antibody fusion proteins with modified fcrn binding sites
US9850296B2 (en) 2010-08-10 2017-12-26 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
JP6017422B2 (ja) 2010-08-10 2016-11-02 エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) 赤血球結合療法
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
KR20240154672A (ko) 2014-02-21 2024-10-25 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) 글리코타겟팅 치료제
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
AU2016215604B2 (en) 2015-02-02 2020-08-13 The University Of Birmingham Targeting moiety peptide epitope complexes having a plurality of T-cell epitopes
EP3638296A1 (en) 2017-06-16 2020-04-22 The University Of Chicago Compositions and methods for inducing immune tolerance
SG11202011078VA (en) 2018-05-09 2020-12-30 Univ Chicago Compositions and methods concerning immune tolerance

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954617A (en) 1986-07-07 1990-09-04 Trustees Of Dartmouth College Monoclonal antibodies to FC receptors for immunoglobulin G on human mononuclear phagocytes
AU616338B2 (en) 1989-02-02 1991-10-24 Mato Maschinen- Und Metallwarenfabrik Curt Matthaei Gmbh & Co Kg Belt skimming device
DK0460076T3 (da) * 1989-02-24 1996-03-25 Univ California Genetisk manipulerede immunoglobuliner
US5612035A (en) 1989-03-21 1997-03-18 The Immune Response Corporation Vaccination against diseases resulting from pathogenic responses by specific T cell populations
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5969109A (en) * 1990-02-28 1999-10-19 Bona; Constantin Chimeric antibodies comprising antigen binding sites and B and T cell epitopes
JP3583420B2 (ja) 1990-10-05 2004-11-04 メダレツクス・インコーポレーテツド 二特異的試薬を用いた標的免疫化
WO1993006135A1 (en) 1991-09-23 1993-04-01 Genentech, Inc. Diagnosing and treating autoimmune disorders
US5474771A (en) 1991-11-15 1995-12-12 The Trustees Of Columbia University In The City Of New York Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same
WO1993010220A1 (en) 1991-11-19 1993-05-27 Anergen, Inc. Soluble mhc molecules and their uses
GB9223377D0 (en) 1992-11-04 1992-12-23 Medarex Inc Humanized antibodies to fc receptors for immunoglobulin on human mononuclear phagocytes
WO1994014847A1 (en) 1992-12-24 1994-07-07 The Regents Of The University Of California Genetically engineered immunoglobulins
US5885573A (en) 1993-06-01 1999-03-23 Arch Development Corporation Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
US5820866A (en) 1994-03-04 1998-10-13 National Jewish Center For Immunology And Respiratory Medicine Product and process for T cell regulation
US6329499B1 (en) 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
DE69637391T2 (de) 1995-05-02 2008-08-14 Alexion Pharmaceuticals, Inc., Cheshire Modifizierte myelin proteinmoleküle
US20020081298A1 (en) * 1997-01-07 2002-06-27 Habib Zaghouani Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
AU5428598A (en) 1997-08-19 1999-03-08 Mount Sinai School Of Medicine Of The City University Of New York, The Epitope-bearing major histocompatibility complex class II element/immunoglobulin chimeric molecules

Similar Documents

Publication Publication Date Title
JP2002510447A5 (OSRAM)
JP2000510751A5 (OSRAM)
JP2000509637A5 (OSRAM)
JP2000507042A5 (OSRAM)
JP2000509942A5 (OSRAM)
JP2001509070A5 (OSRAM)
JP2001515619A5 (OSRAM)
JP2000509587A5 (OSRAM)
JP2000507369A5 (OSRAM)
JP2000507433A5 (OSRAM)
JP2000508866A5 (OSRAM)
JP2000510793A5 (OSRAM)
JP2000508841A5 (OSRAM)
JP2000508680A5 (OSRAM)
JP2002512601A5 (OSRAM)
JP2000509853A5 (OSRAM)
JP2000509755A5 (OSRAM)
JP2000510969A5 (OSRAM)
JP2000510247A5 (OSRAM)
JP2001513765A5 (OSRAM)
JP2000508102A5 (OSRAM)
JP2000508836A5 (OSRAM)
JP2000509520A5 (OSRAM)
JP2000507434A5 (OSRAM)
JP2000508880A5 (OSRAM)