JP2001506986A5 - - Google Patents

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Publication number
JP2001506986A5
JP2001506986A5 JP1998525838A JP52583898A JP2001506986A5 JP 2001506986 A5 JP2001506986 A5 JP 2001506986A5 JP 1998525838 A JP1998525838 A JP 1998525838A JP 52583898 A JP52583898 A JP 52583898A JP 2001506986 A5 JP2001506986 A5 JP 2001506986A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998525838A
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English (en)
Japanese (ja)
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JP2001506986A (ja
JP4094066B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/022355 external-priority patent/WO1998024804A2/en
Publication of JP2001506986A publication Critical patent/JP2001506986A/ja
Publication of JP2001506986A5 publication Critical patent/JP2001506986A5/ja
Application granted granted Critical
Publication of JP4094066B2 publication Critical patent/JP4094066B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP52583898A 1996-12-06 1997-12-05 インターロイキン−1β変換酵素のインヒビター Expired - Lifetime JP4094066B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3212996P 1996-12-06 1996-12-06
US60/032,129 1996-12-06
US4193897P 1997-04-04 1997-04-04
US60/041,938 1997-04-04
US5079697P 1997-06-26 1997-06-26
US60/050,796 1997-06-26
PCT/US1997/022355 WO1998024804A2 (en) 1996-12-06 1997-12-05 INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME

Publications (3)

Publication Number Publication Date
JP2001506986A JP2001506986A (ja) 2001-05-29
JP2001506986A5 true JP2001506986A5 (enExample) 2005-08-11
JP4094066B2 JP4094066B2 (ja) 2008-06-04

Family

ID=27364031

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52583898A Expired - Lifetime JP4094066B2 (ja) 1996-12-06 1997-12-05 インターロイキン−1β変換酵素のインヒビター

Country Status (8)

Country Link
US (1) US6350741B1 (enExample)
EP (1) EP0942925B1 (enExample)
JP (1) JP4094066B2 (enExample)
AT (1) ATE346085T1 (enExample)
AU (1) AU7624798A (enExample)
CA (1) CA2274250A1 (enExample)
DE (1) DE69736984T2 (enExample)
WO (1) WO1998024804A2 (enExample)

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CN1835769B (zh) * 2002-12-30 2011-06-29 比奥根艾迪克Ma公司 Kim-1拮抗剂及其在免疫系统调节中的应用
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US9512125B2 (en) * 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
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US8993580B2 (en) 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
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US20110224223A1 (en) * 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
WO2010036380A1 (en) 2008-09-26 2010-04-01 Intellikine, Inc. Heterocyclic kinase inhibitors
WO2010045542A2 (en) 2008-10-16 2010-04-22 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
CN102186525B (zh) 2008-10-17 2016-02-03 皇家飞利浦电子股份有限公司 医疗通气机中的体积控制
US8476431B2 (en) 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
WO2010129816A2 (en) 2009-05-07 2010-11-11 Intellikine, Inc. Heterocyclic compounds and uses thereof
WO2011047384A2 (en) 2009-10-16 2011-04-21 The Regents Of The University Of California Methods of inhibiting ire1
JP5951600B2 (ja) 2010-05-21 2016-07-13 インフィニティー ファーマシューティカルズ, インコーポレイテッド キナーゼ調節のための、化合物、組成物および方法
US20130302282A1 (en) 2010-10-26 2013-11-14 Presidio Pharmaceuticals, Inc. Inhibitors of Hepatitis C Virus
US8901133B2 (en) 2010-11-10 2014-12-02 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
KR20180080358A (ko) 2011-01-10 2018-07-11 인피니티 파마슈티칼스, 인코포레이티드 이소퀴놀린온 및 이의 고체 형태의 제조 방법
JP6130305B2 (ja) 2011-02-23 2017-05-17 インテリカイン, エルエルシー キナーゼ阻害剤の組み合わせおよびそれらの使用
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CN103930422A (zh) 2011-07-19 2014-07-16 无限药品股份有限公司 杂环化合物及其用途
US9956260B1 (en) 2011-07-22 2018-05-01 The J. David Gladstone Institutes Treatment of HIV-1 infection and AIDS
CN103998442B (zh) 2011-08-29 2016-09-14 无限药品股份有限公司 杂环化合物及其用途
MX370814B (es) 2011-09-02 2020-01-08 Univ California Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
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IL287136B2 (en) 2016-02-05 2023-09-01 Denali Therapeutics Inc Receptor inhibitors - interacting with protein kinase 1
US10759806B2 (en) 2016-03-17 2020-09-01 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
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HUE058802T2 (hu) 2016-12-09 2022-09-28 Denali Therapeutics Inc RIPK1 inhibitorokként alkalmas vegyületek
US11072607B2 (en) 2016-12-16 2021-07-27 Genentech, Inc. Inhibitors of RIP1 kinase and methods of use thereof
CN112074519B (zh) 2018-04-20 2024-08-02 豪夫迈·罗氏有限公司 作为rip1激酶抑制剂用于治疗例如肠易激综合征(ibs)的化合物
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EP0698015A1 (en) * 1993-05-14 1996-02-28 Genentech, Inc. Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole
US5580979A (en) * 1994-03-15 1996-12-03 Trustees Of Tufts University Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
US5716929A (en) * 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme
JPH09295996A (ja) * 1996-03-06 1997-11-18 Takeda Chem Ind Ltd システインプロテアーゼ阻害化合物

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