|
US7704944B2
(en)
|
1997-08-14 |
2010-04-27 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
|
|
IL121860A0
(en)
|
1997-08-14 |
1998-02-22 |
Yeda Res & Dev |
Interleukin-18 binding proteins their preparation and use
|
|
US7220717B2
(en)
|
1997-08-14 |
2007-05-22 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use
|
|
FR2781483A1
(fr)
*
|
1998-07-21 |
2000-01-28 |
Hoechst Marion Roussel Inc |
Derives de thioazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicament et compositions pharmaceutiques les renfermant
|
|
US7015212B1
(en)
|
1999-05-12 |
2006-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Thiazepine inhibitors of HIV-1 integrase
|
|
KR100857376B1
(ko)
*
|
2001-01-29 |
2008-09-05 |
라보라토리스 세로노 에스.에이. |
심장 질환의 치료 및/또는 예방에 사용되는 il-18저해물질
|
|
US20050074434A1
(en)
*
|
2001-02-23 |
2005-04-07 |
Tomoaki Hoshino |
Remedies for metabolic bone diseases
|
|
US7001899B2
(en)
*
|
2002-06-10 |
2006-02-21 |
The Procter & Gamble Company |
Interleukin converting enzyme inhibitors
|
|
US20040151704A1
(en)
|
2002-06-28 |
2004-08-05 |
Xcyte Therapies, Inc. |
Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
SI1585546T1
(sl)
*
|
2002-12-30 |
2008-12-31 |
Biogen Idec Inc |
KIM-1 antagonisti in uporaba za moduliranje imunskega sistema
|
|
CA2566362C
(en)
*
|
2004-05-15 |
2013-09-10 |
Vertex Pharmaceuticals Incorporated |
Treating seizures using ice inhibitors
|
|
EP1831225A2
(en)
*
|
2004-11-19 |
2007-09-12 |
The Regents of the University of California |
Anti-inflammatory pyrazolopyrimidines
|
|
BRPI0608254A2
(pt)
|
2005-03-02 |
2009-12-08 |
Biogen Idec Inc |
anticorpos kim-1 para o tratamento de condições mediadas por th2
|
|
EA200870409A1
(ru)
*
|
2006-04-04 |
2009-04-28 |
Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния |
Антагонисты киназы pi3
|
|
GB2467670B
(en)
*
|
2007-10-04 |
2012-08-01 |
Intellikine Inc |
Chemical entities and therapeutic uses thereof
|
|
CA2711558C
(en)
*
|
2008-01-04 |
2016-12-13 |
Intellikine, Inc. |
Phosphatidyl inositol-3 kinase inhibiting compounds
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
US8993580B2
(en)
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
|
JP5547099B2
(ja)
*
|
2008-03-14 |
2014-07-09 |
インテリカイン, エルエルシー |
キナーゼ阻害剤および使用方法
|
|
WO2010006072A2
(en)
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Mtor modulators and uses thereof
|
|
AU2009268611B2
(en)
*
|
2008-07-08 |
2015-04-09 |
Intellikine, Llc |
Kinase inhibitors and methods of use
|
|
JP5731978B2
(ja)
|
2008-09-26 |
2015-06-10 |
インテリカイン, エルエルシー |
複素環キナーゼ阻害剤
|
|
CA2740885C
(en)
|
2008-10-16 |
2018-04-03 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
|
EP2334359B1
(en)
|
2008-10-17 |
2020-07-22 |
Koninklijke Philips N.V. |
Volume control in a medical ventilator
|
|
US8476282B2
(en)
*
|
2008-11-03 |
2013-07-02 |
Intellikine Llc |
Benzoxazole kinase inhibitors and methods of use
|
|
EP2427195B1
(en)
|
2009-05-07 |
2019-05-01 |
Intellikine, LLC |
Heterocyclic compounds and uses thereof
|
|
WO2011047384A2
(en)
|
2009-10-16 |
2011-04-21 |
The Regents Of The University Of California |
Methods of inhibiting ire1
|
|
AU2011255218B2
(en)
|
2010-05-21 |
2015-03-12 |
Infinity Pharmaceuticals, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
|
CN103269586B
(zh)
|
2010-10-26 |
2015-07-15 |
普雷西迪奥制药公司 |
丙型肝炎病毒抑制剂
|
|
JP2013545749A
(ja)
|
2010-11-10 |
2013-12-26 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
複素環化合物及びその使用
|
|
AU2012205669B2
(en)
|
2011-01-10 |
2015-08-20 |
Infinity Pharmaceuticals Inc. |
Processes for preparing isoquinolinones and solid forms of isoquinolinones
|
|
JP6130305B2
(ja)
|
2011-02-23 |
2017-05-17 |
インテリカイン, エルエルシー |
キナーゼ阻害剤の組み合わせおよびそれらの使用
|
|
JP6027610B2
(ja)
|
2011-07-19 |
2016-11-16 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
複素環式化合物及びその使用
|
|
US9056877B2
(en)
|
2011-07-19 |
2015-06-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US9956260B1
(en)
|
2011-07-22 |
2018-05-01 |
The J. David Gladstone Institutes |
Treatment of HIV-1 infection and AIDS
|
|
EP2751093A1
(en)
|
2011-08-29 |
2014-07-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
MX370814B
(es)
|
2011-09-02 |
2020-01-08 |
Univ California |
Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
|
MX2015003874A
(es)
|
2012-09-26 |
2015-12-16 |
Univ California |
Modulacion de ire1.
|
|
KR102229478B1
(ko)
|
2012-11-01 |
2021-03-18 |
인피니티 파마슈티칼스, 인코포레이티드 |
Pi3 키나아제 동형단백질 조절인자를 사용하는 암의 치료
|
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
PE20160685A1
(es)
|
2013-10-04 |
2016-07-23 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos
|
|
CN103804367B
(zh)
*
|
2014-02-28 |
2016-09-14 |
天津药物研究院 |
苯并氮杂卓衍生物、其制备方法和用途
|
|
SG10201808053XA
(en)
|
2014-03-19 |
2018-10-30 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
|
|
US20150320755A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
US9708348B2
(en)
|
2014-10-03 |
2017-07-18 |
Infinity Pharmaceuticals, Inc. |
Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
|
|
TWI788830B
(zh)
|
2015-07-02 |
2023-01-01 |
瑞士商赫孚孟拉羅股份公司 |
雙環內醯胺及其使用方法
|
|
US10160761B2
(en)
|
2015-09-14 |
2018-12-25 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinones, and process of making, composition comprising, and methods of using the same
|
|
SG10201913587WA
(en)
|
2016-02-05 |
2020-02-27 |
Denali Therapeutics Inc |
Inhibitors of receptor-interacting protein kinase 1
|
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
|
US10919914B2
(en)
|
2016-06-08 |
2021-02-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
MX391135B
(es)
|
2016-06-24 |
2025-03-21 |
Infinity Pharmaceuticals Inc |
Terapias de combinacion.
|
|
EP3526219B1
(en)
|
2016-10-17 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Bicyclic pyridone lactams and methods of use thereof
|
|
DK3552017T3
(da)
|
2016-12-09 |
2022-05-16 |
Denali Therapeutics Inc |
Forbindelser, der er anvendelige som ripk1-inhibitorer
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
JP7398391B2
(ja)
|
2018-04-20 |
2023-12-14 |
エフ. ホフマン-ラ ロシュ アーゲー |
N-[4-オキソ-2,3-ジヒドロ-1,5-ベンズオキサゼピン-3-イル]-5,6-ジヒドロ-4H-ピロロ[1,2-b]ピラゾール-2-カルボキサミド誘導体及び例えば過敏性腸症候群(IBS)を処置するためのRIP1キナーゼ阻害剤としての関連化合物
|
|
WO2023137035A1
(en)
|
2022-01-12 |
2023-07-20 |
Denali Therapeutics Inc. |
Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide
|
|
WO2026082873A1
(en)
|
2024-10-17 |
2026-04-23 |
Institut National de la Santé et de la Recherche Médicale |
Use of caspase-1 inhibitors for treating ineffective erythropoiesis in patients suffering from sickle cell disease
|