|
IL121860A0
(en)
|
1997-08-14 |
1998-02-22 |
Yeda Res & Dev |
Interleukin-18 binding proteins their preparation and use
|
|
US7220717B2
(en)
|
1997-08-14 |
2007-05-22 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use
|
|
US7704944B2
(en)
|
1997-08-14 |
2010-04-27 |
Yeda Research And Development Company Ltd. |
Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
|
|
FR2781483A1
(fr)
*
|
1998-07-21 |
2000-01-28 |
Hoechst Marion Roussel Inc |
Derives de thioazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicament et compositions pharmaceutiques les renfermant
|
|
US7015212B1
(en)
|
1999-05-12 |
2006-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Thiazepine inhibitors of HIV-1 integrase
|
|
IL157024A0
(en)
*
|
2001-01-29 |
2004-02-08 |
Applied Research Systems |
Il-18 inhibitors in heart disease
|
|
US20050074434A1
(en)
*
|
2001-02-23 |
2005-04-07 |
Tomoaki Hoshino |
Remedies for metabolic bone diseases
|
|
US7001899B2
(en)
*
|
2002-06-10 |
2006-02-21 |
The Procter & Gamble Company |
Interleukin converting enzyme inhibitors
|
|
ES2422193T3
(es)
|
2002-06-28 |
2013-09-09 |
Life Technologies Corp |
Métodos para restaurar el repertorio inmune en pacientes con defectos inmunológicos relacionados con la autoinmunidad y trasplante de órganos o de células madre hematopoyéticas
|
|
CA2512138C
(en)
*
|
2002-12-30 |
2013-07-16 |
Biogen Idec Ma Inc. |
Kim-1 antagonists and use to modulate immune system
|
|
PL217743B1
(pl)
*
|
2004-05-15 |
2014-08-29 |
Vertex Pharma |
Zastosowanie inhibitorów ICE/kaspazy-1 do leczenia napadów i konwulsji w epilepsji oraz zawierające je kompozycja farmaceutyczna i zestaw
|
|
US9512125B2
(en)
*
|
2004-11-19 |
2016-12-06 |
The Regents Of The University Of California |
Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
|
|
EP1865985B1
(en)
|
2005-03-02 |
2010-08-25 |
Biogen Idec MA Inc. |
Kim-1 antibodies for treatment of th2-mediated conditions
|
|
KR20150038395A
(ko)
*
|
2006-04-04 |
2015-04-08 |
더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 |
키나제 길항물질
|
|
US20110160232A1
(en)
*
|
2007-10-04 |
2011-06-30 |
Pingda Ren |
Certain chemical entities and therapeutic uses thereof
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
BRPI0906473A8
(pt)
|
2008-01-04 |
2016-02-10 |
Intellikine Inc |
Certas entidades químicas, composições e métodos
|
|
WO2009114870A2
(en)
*
|
2008-03-14 |
2009-09-17 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
|
US8993580B2
(en)
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
|
MX2011000216A
(es)
*
|
2008-07-08 |
2011-03-29 |
Intellikine Inc |
Inhibidores de cinasa y metodos para su uso.
|
|
US20110224223A1
(en)
*
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
|
WO2010036380A1
(en)
|
2008-09-26 |
2010-04-01 |
Intellikine, Inc. |
Heterocyclic kinase inhibitors
|
|
AU2009305669A1
(en)
|
2008-10-16 |
2010-04-22 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
|
BRPI0914035A2
(pt)
*
|
2008-10-17 |
2015-11-03 |
Koninkl Philips Electronics Nv |
ventilador e método para ventilar um paciente usando um ventilador
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
JP5789252B2
(ja)
|
2009-05-07 |
2015-10-07 |
インテリカイン， エルエルシー |
複素環式化合物およびその使用
|
|
US8980899B2
(en)
|
2009-10-16 |
2015-03-17 |
The Regents Of The University Of California |
Methods of inhibiting Ire1
|
|
JP5951600B2
(ja)
|
2010-05-21 |
2016-07-13 |
インフィニティー ファーマシューティカルズ， インコーポレイテッド |
キナーゼ調節のための、化合物、組成物および方法
|
|
CN103269586B
(zh)
|
2010-10-26 |
2015-07-15 |
普雷西迪奥制药公司 |
丙型肝炎病毒抑制剂
|
|
WO2012064973A2
(en)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
EP3238722B1
(en)
|
2011-01-10 |
2019-03-13 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinones
|
|
TWI592411B
(zh)
|
2011-02-23 |
2017-07-21 |
英特爾立秦有限責任公司 |
激酶抑制劑之組合及其用途
|
|
EP2734520B1
(en)
|
2011-07-19 |
2016-09-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US9056877B2
(en)
|
2011-07-19 |
2015-06-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US9956260B1
(en)
|
2011-07-22 |
2018-05-01 |
The J. David Gladstone Institutes |
Treatment of HIV-1 infection and AIDS
|
|
PE20141371A1
(es)
|
2011-08-29 |
2014-10-13 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos
|
|
WO2013077921A2
(en)
|
2011-09-02 |
2013-05-30 |
The Regents Of The University Of California |
Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
|
CA2886240A1
(en)
|
2012-09-26 |
2014-04-03 |
The Regents Of The University Of California |
Modulation of ire1
|
|
RU2702908C2
(ru)
|
2012-11-01 |
2019-10-14 |
Инфинити Фармасьютикалз, Инк. |
Лечение злокачественных опухолей с использованием модуляторов изоформ pi3-киназы
|
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
|
EP3964507A1
(en)
|
2013-10-04 |
2022-03-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2015051241A1
(en)
|
2013-10-04 |
2015-04-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
CN103804367B
(zh)
*
|
2014-02-28 |
2016-09-14 |
天津药物研究院 |
苯并氮杂卓衍生物、其制备方法和用途
|
|
CN106456628A
(zh)
|
2014-03-19 |
2017-02-22 |
无限药品股份有限公司 |
用于治疗PI3K‑γ介导的障碍的杂环化合物
|
|
WO2015160975A2
(en)
|
2014-04-16 |
2015-10-22 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
WO2016054491A1
(en)
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
RU2716136C2
(ru)
|
2015-07-02 |
2020-03-06 |
Ф. Хоффманн-Ля Рош Аг |
Бициклические лактамы и способы их применения
|
|
CN114230571B
(zh)
|
2015-09-14 |
2025-07-08 |
无限药品股份有限公司 |
异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
|
|
US9815850B2
(en)
|
2016-02-05 |
2017-11-14 |
Denali Therapeutics Inc. |
Compounds, compositions and methods
|
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
|
US10919914B2
(en)
|
2016-06-08 |
2021-02-16 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
EP3474856B1
(en)
|
2016-06-24 |
2022-09-14 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
JP7349359B2
(ja)
|
2016-10-17 |
2023-09-22 |
エフ． ホフマン－ラ ロシュ アーゲー |
二環式ピリドンラクタム及びその使用方法。
|
|
LT3552017T
(lt)
|
2016-12-09 |
2022-05-10 |
Denali Therapeutics Inc. |
Junginiai, naudotini kaip ripk1 inhibitoriai
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
EP3781571B1
(en)
|
2018-04-20 |
2024-01-17 |
F. Hoffmann-La Roche AG |
N-[4-oxo-2,3-dihydro-pyrido[3,2-b][1,4]oxazepin-3-yl]-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazole-2-carboxamide derivatives and related compounds as rip1 kinase inhibitors for treating e.g. irritable bowel syndrome (ibs)
|
|
EP4463229A1
(en)
|
2022-01-12 |
2024-11-20 |
Denali Therapeutics Inc. |
Crystalline forms of (s)-5-benzyl-n-(5-methyl-4-oxo-2, 3,4,5- tetrahydropyrido [3,2-b] [l,4]oxazepin-3-yl)-4h-l,2,4-triazole-3-carboxamide
|
|
WO2026082873A1
(en)
|
2024-10-17 |
2026-04-23 |
Institut National de la Santé et de la Recherche Médicale |
Use of caspase-1 inhibitors for treating ineffective erythropoiesis in patients suffering from sickle cell disease
|