JP2001502170A5 - - Google Patents

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Publication number
JP2001502170A5
JP2001502170A5 JP1998516242A JP51624298A JP2001502170A5 JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5 JP 1998516242 A JP1998516242 A JP 1998516242A JP 51624298 A JP51624298 A JP 51624298A JP 2001502170 A5 JP2001502170 A5 JP 2001502170A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998516242A
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English (en)
Japanese (ja)
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JP4005637B2 (ja
JP2001502170A (ja
Filing date
Publication date
Priority claimed from EP96115873A external-priority patent/EP0834569A1/en
Application filed filed Critical
Publication of JP2001502170A publication Critical patent/JP2001502170A/ja
Publication of JP2001502170A5 publication Critical patent/JP2001502170A5/ja
Application granted granted Critical
Publication of JP4005637B2 publication Critical patent/JP4005637B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP51624298A 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ Expired - Fee Related JP4005637B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96115873.0 1996-10-03
EP96115873A EP0834569A1 (en) 1996-10-03 1996-10-03 Thermostable DNA polymerase from carboxydothermus hydrogenoformans
PCT/EP1997/005391 WO1998014589A1 (en) 1996-10-03 1997-10-01 Thermostable dna polymerase from carboxydothermus hydrogenoformans

Publications (3)

Publication Number Publication Date
JP2001502170A JP2001502170A (ja) 2001-02-20
JP2001502170A5 true JP2001502170A5 (https=) 2005-05-12
JP4005637B2 JP4005637B2 (ja) 2007-11-07

Family

ID=8223262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51624298A Expired - Fee Related JP4005637B2 (ja) 1996-10-03 1997-10-01 カルボキシドテルムス ヒドロゲノホルマンス由来の熱安定dnaポリメラーゼ

Country Status (12)

Country Link
US (1) US6468775B1 (https=)
EP (2) EP0834569A1 (https=)
JP (1) JP4005637B2 (https=)
AT (1) ATE357527T1 (https=)
AU (1) AU717009B2 (https=)
CA (1) CA2268014C (https=)
DE (1) DE69737502T2 (https=)
IL (1) IL129085A (https=)
NO (1) NO323846B1 (https=)
NZ (1) NZ334652A (https=)
RU (1) RU2197524C2 (https=)
WO (1) WO1998014589A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0921196A1 (en) * 1997-12-02 1999-06-09 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
EP0922765B1 (en) * 1997-12-02 2005-11-23 Roche Diagnostics GmbH Modified DNA-polymerase from carboxydothermus hydrogenoformans and its use for coupled reverse transcription and polymerase chain reaction
US20030228616A1 (en) * 1999-10-29 2003-12-11 Stratagene DNA polymerase mutants with reverse transcriptase activity
US20050123940A1 (en) * 1999-10-29 2005-06-09 Stratagene California Compositions and methods for synthesizing cDNA
US20040009486A1 (en) * 1999-10-29 2004-01-15 Sorge Joseph A. Compositions and methods utilizing DNA polymerases
US7384739B2 (en) * 2001-11-14 2008-06-10 Toyo Boseki Kabushiki Kaisha Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof
BRPI0408967B8 (pt) 2003-03-31 2021-07-27 Hoffmann La Roche kit e métodos para detecção de um ácido nucléico de vários membros do sorogrupo do vírus da encefalite japonesa em uma amostra biológica sob condições de hibridização rigorosas
US7927580B2 (en) 2004-03-16 2011-04-19 Nanirx, Inc. Tat-based immunomodulatory compositions and methods of their discovery and use
US8962293B2 (en) 2006-10-18 2015-02-24 Roche Molecular Systems, Inc. DNA polymerases and related methods
NZ595060A (en) 2009-03-23 2013-05-31 Pin Pharma Inc Treatment of cancer with immunostimulatory hiv tat derivative polypeptides
JP5841136B2 (ja) 2010-06-18 2016-01-13 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 増大した3’末端ミスマッチ識別能を有するdnaポリメラーゼ
KR101622442B1 (ko) 2010-06-18 2016-05-19 에프. 호프만-라 로슈 아게 3’―미스매치 구별이 증가된 dna 중합효소
WO2011157436A1 (en) 2010-06-18 2011-12-22 Roche Diagnostics Gmbh Dna polymerases with increased 3'-mismatch discrimination
CA2802000C (en) 2010-06-18 2016-08-16 F. Hoffmann-La Roche Ag Dna polymerases with increased 3'-mismatch discrimination
CA2801997C (en) 2010-06-18 2016-05-31 F. Hoffmann-La Roche Ag Dna polymerases with increased 3'-mismatch discrimination
JP5926246B2 (ja) 2010-06-18 2016-05-25 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 増大した3’末端ミスマッチ識別能を有するdnaポリメラーゼ
ES2536978T3 (es) 2010-06-18 2015-06-01 F. Hoffmann-La Roche Ag ADN polimerasas con discriminación incrementada de no correspondencias 3'
CA2802239C (en) 2010-06-18 2016-08-23 F. Hoffmann-La Roche Ag Dna polymerases with increased 3'-mismatch discrimination
WO2012110061A1 (en) 2011-02-15 2012-08-23 Roche Diagnostics Gmbh Dna polymerases with increased 3'-mismatch discrimination
EP2697372B1 (en) 2011-04-11 2015-12-16 Roche Diagnostics GmbH Dna polymerases with improved activity
WO2013013822A1 (en) 2011-07-28 2013-01-31 Roche Diagnostics Gmbh Dna polymerases with improved activity
JP6144697B2 (ja) 2011-12-08 2017-06-07 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
WO2013083262A1 (en) 2011-12-08 2013-06-13 Roche Diagnostics Gmbh Dna polymerases with improved activity
JP6140182B2 (ja) 2011-12-08 2017-05-31 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 改善された活性を有するdnaポリメラーゼ
JP2016533352A (ja) 2013-10-04 2016-10-27 ピーアイエヌ ファーマ インコーポレイテッド 免疫刺激性HIV Tat誘導体ポリペプチドによる癌の治療
ES2969883T3 (es) 2018-03-21 2024-05-23 Hoffmann La Roche ADN polimerasas para la incorporación eficiente y eficaz de dNTP metilados
JP7504872B2 (ja) 2018-09-13 2024-06-24 エフ. ホフマン-ラ ロシュ アーゲー 改善されたストランド置換能力を有する変異体dnaポリメラーゼ
CN111733145A (zh) * 2020-07-01 2020-10-02 济南国科医工科技发展有限公司 重组酶的纯化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5374553A (en) * 1986-08-22 1994-12-20 Hoffmann-La Roche Inc. DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
US5912155A (en) * 1994-09-30 1999-06-15 Life Technologies, Inc. Cloned DNA polymerases from Thermotoga neapolitana

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