JP2001501613A5 - - Google Patents
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- Publication number
- JP2001501613A5 JP2001501613A5 JP1998515906A JP51590698A JP2001501613A5 JP 2001501613 A5 JP2001501613 A5 JP 2001501613A5 JP 1998515906 A JP1998515906 A JP 1998515906A JP 51590698 A JP51590698 A JP 51590698A JP 2001501613 A5 JP2001501613 A5 JP 2001501613A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/719,488 | 1996-09-25 | ||
| US08/719,488 US5750737A (en) | 1996-09-25 | 1996-09-25 | Method for paclitaxel synthesis |
| PCT/US1997/017230 WO1998013360A1 (en) | 1996-09-25 | 1997-09-25 | Method for paclitaxel synthesis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001501613A JP2001501613A (ja) | 2001-02-06 |
| JP2001501613A5 true JP2001501613A5 (enExample) | 2005-05-12 |
Family
ID=24890263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10515906A Ceased JP2001501613A (ja) | 1996-09-25 | 1997-09-25 | パクリタキセルの合成方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5750737A (enExample) |
| EP (1) | EP0935596B1 (enExample) |
| JP (1) | JP2001501613A (enExample) |
| CN (2) | CN1097586C (enExample) |
| AT (1) | ATE288427T1 (enExample) |
| AU (1) | AU736591B2 (enExample) |
| CA (1) | CA2266892C (enExample) |
| DE (1) | DE69732421D1 (enExample) |
| IL (1) | IL129100A (enExample) |
| WO (1) | WO1998013360A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5973170A (en) * | 1996-09-25 | 1999-10-26 | Napro Biotherapuetics, Inc. | C-7 metal alkoxides of baccatin III |
| US6448417B1 (en) * | 1998-05-01 | 2002-09-10 | Napro Biotherapeutics, Inc. | Methods and useful intermediates for paclitaxel synthesis from C-7, C-10 di-cbz 10-deacetylbaccatin III |
| US6002025A (en) * | 1999-02-24 | 1999-12-14 | Bcm Developement Inc. | Method for the purification of taxanes |
| US6136999A (en) * | 1999-06-21 | 2000-10-24 | Napro Biotherapeutics, Inc. | C-2 hydroxyl protected-n-acyl (2R,3S)-3-phenylisoserine substituted phenyl activated esters and method for production thereof |
| US6143902A (en) * | 1999-06-21 | 2000-11-07 | Napro Biotherapeutics, Inc. | C-2 hydroxyl protected-N-acyl (2R,3S)-3-phenylisoserine N-imido activated esters and method for production thereof |
| EP1192126A1 (en) * | 1999-06-21 | 2002-04-03 | Napro Biotherapeutics, Inc. | C-2 hydroxyl protected-n-acyl(2r,3s)-3-phenylisoserine activated esters and methods for production thereof |
| US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
| US6452024B1 (en) | 2000-02-22 | 2002-09-17 | Chaichem Pharmaceuticals International | Process for extraction and purification of paclitaxel from natural sources |
| US6358996B1 (en) | 2000-06-09 | 2002-03-19 | Napro Biotherapeutics, Inc. | Stable isotope labeling of paclitaxel |
| US6825166B2 (en) * | 2001-03-23 | 2004-11-30 | Tapestry Pharmaceuticals, Inc. | Molecular conjugates for use in treatment of cancer |
| US6452025B1 (en) | 2001-04-25 | 2002-09-17 | Napro Biotherapeutics, Inc. | Three-step conversion of protected taxane ester to paclitaxel |
| US6479679B1 (en) | 2001-04-25 | 2002-11-12 | Napro Biotherapeutics, Inc. | Two-step conversion of protected taxane ester to paclitaxel |
| US6653501B2 (en) | 2001-06-27 | 2003-11-25 | Napro Biotherapeutics, Inc. | Chiral resolution method for producing compounds useful in the synthesis of taxanes |
| CA2479665C (en) * | 2002-03-20 | 2011-08-30 | Elan Pharma International Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
| US6759539B1 (en) | 2003-02-27 | 2004-07-06 | Chaichem Pharmaceuticals International | Process for isolation and purification of paclitaxel from natural sources |
| US20050272807A1 (en) * | 2004-06-04 | 2005-12-08 | Phytogen Life Sciences Inc. | Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel |
| JP2009521435A (ja) * | 2005-12-21 | 2009-06-04 | タペストリー ファーマシューティカルズ インコーポレーテッド | タキサンを形成するための新規化合物および方法ならびにその使用 |
| US20090306400A1 (en) * | 2006-03-27 | 2009-12-10 | Henri John T | Convergent process for the synthesis of taxane derivatives. |
| US20100137221A1 (en) * | 2007-02-27 | 2010-06-03 | University Utah Research Foundation | Peptides that interact with topoisomerase i and methods thereof |
| TW201127384A (en) * | 2009-11-18 | 2011-08-16 | Nerviano Medical Sciences Srl | Therapeutic combination comprising a Cdc7 inhibitor and an antineoplastic agent |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34277A (en) * | 1862-01-28 | Improvement in lamps | ||
| FR2601676B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| USRE34277E (en) * | 1988-04-06 | 1993-06-08 | Centre National De La Recherche Scientifique | Process for preparing taxol |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
| US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| US5175315A (en) * | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| US5136060A (en) * | 1989-11-14 | 1992-08-04 | Florida State University | Method for preparation of taxol using an oxazinone |
| US5015744A (en) * | 1989-11-14 | 1991-05-14 | Florida State University | Method for preparation of taxol using an oxazinone |
| FR2658513B1 (fr) * | 1990-02-21 | 1994-02-04 | Rhone Poulenc Sante | Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r). |
| FR2680506B1 (fr) * | 1991-08-19 | 1994-09-02 | Rhone Poulenc Rorer Sa | Procede de preparation de derives de la beta-phenylisoserine et leur utilisation. |
| US5229526A (en) * | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
| US5399726A (en) * | 1993-01-29 | 1995-03-21 | Florida State University | Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups |
| FR2687150B1 (fr) * | 1992-02-07 | 1995-04-28 | Rhone Poulenc Rorer Sa | Procede de preparation de derives du taxane. |
| FR2687151B1 (fr) * | 1992-02-07 | 1994-03-25 | Rhone Poulenc Rorer Sa | Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| US5948919A (en) * | 1993-02-05 | 1999-09-07 | Napro Biotherapeutics, Inc. | Paclitaxel synthesis from precursor compounds and methods of producing the same |
| JP3031715B2 (ja) * | 1993-02-05 | 2000-04-10 | ブリン モーアー カレッジ | 様々なａ環側鎖を有するタキソール、類似体及び中間体の合成 |
-
1996
- 1996-09-25 US US08/719,488 patent/US5750737A/en not_active Expired - Lifetime
-
1997
- 1997-09-02 US US08/922,684 patent/US6133462A/en not_active Expired - Fee Related
- 1997-09-25 CA CA002266892A patent/CA2266892C/en not_active Expired - Fee Related
- 1997-09-25 DE DE69732421T patent/DE69732421D1/de not_active Expired - Lifetime
- 1997-09-25 IL IL12910097A patent/IL129100A/en not_active IP Right Cessation
- 1997-09-25 AU AU45021/97A patent/AU736591B2/en not_active Expired
- 1997-09-25 WO PCT/US1997/017230 patent/WO1998013360A1/en not_active Ceased
- 1997-09-25 EP EP97943583A patent/EP0935596B1/en not_active Expired - Lifetime
- 1997-09-25 JP JP10515906A patent/JP2001501613A/ja not_active Ceased
- 1997-09-25 AT AT97943583T patent/ATE288427T1/de not_active IP Right Cessation
- 1997-09-25 CN CN97198130A patent/CN1097586C/zh not_active Expired - Lifetime
-
2002
- 2002-08-16 CN CN02130213A patent/CN1440967A/zh active Pending