JP2001500723A5 - - Google Patents

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Publication number
JP2001500723A5
JP2001500723A5 JP1997542848A JP54284897A JP2001500723A5 JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5 JP 1997542848 A JP1997542848 A JP 1997542848A JP 54284897 A JP54284897 A JP 54284897A JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997542848A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001500723A (ja
JP3945822B2 (ja
Filing date
Publication date
Priority claimed from US08/653,226 external-priority patent/US6514731B1/en
Application filed filed Critical
Priority claimed from PCT/US1997/008950 external-priority patent/WO1997044469A2/en
Publication of JP2001500723A publication Critical patent/JP2001500723A/ja
Publication of JP2001500723A5 publication Critical patent/JP2001500723A5/ja
Application granted granted Critical
Publication of JP3945822B2 publication Critical patent/JP3945822B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP54284897A 1996-05-24 1997-05-23 複数エピトープ融合タンパク質 Expired - Lifetime JP3945822B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/653,226 1996-05-24
US08/653,226 US6514731B1 (en) 1996-05-24 1996-05-24 Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
US08/859,524 1997-05-20
US08/859,524 US6428792B1 (en) 1996-05-24 1997-05-20 Hepatitis C virus multiple copy epitope fusion antigens
PCT/US1997/008950 WO1997044469A2 (en) 1996-05-24 1997-05-23 Multiple epitope fusion protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007027374A Division JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Publications (3)

Publication Number Publication Date
JP2001500723A JP2001500723A (ja) 2001-01-23
JP2001500723A5 true JP2001500723A5 (enExample) 2005-01-13
JP3945822B2 JP3945822B2 (ja) 2007-07-18

Family

ID=27096474

Family Applications (2)

Application Number Title Priority Date Filing Date
JP54284897A Expired - Lifetime JP3945822B2 (ja) 1996-05-24 1997-05-23 複数エピトープ融合タンパク質
JP2007027374A Withdrawn JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007027374A Withdrawn JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Country Status (11)

Country Link
EP (1) EP0935662B1 (enExample)
JP (2) JP3945822B2 (enExample)
AT (1) ATE311463T1 (enExample)
AU (1) AU719929B2 (enExample)
CA (1) CA2250723C (enExample)
DE (1) DE69734776T2 (enExample)
DK (1) DK0935662T3 (enExample)
ES (1) ES2251028T3 (enExample)
IL (1) IL126460A (enExample)
NZ (1) NZ333431A (enExample)
WO (1) WO1997044469A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322965B1 (en) * 1997-02-10 2001-11-27 Advanced Life Science Institute, Inc. Chimera antigen peptide
WO1999015901A1 (en) 1997-09-22 1999-04-01 Chiron Corporation Buffers for stabilizing antigens
DE69837155T2 (de) * 1997-09-22 2007-06-21 Novartis Vaccines and Diagnostics, Inc., Emeryville Verfahren zum nachweiss von antikörpern in einer probe
EP1056762A4 (en) * 1998-01-30 2003-07-23 Gen Hospital Corp GENETIC IMMUNIZATION WITH HEPATITIS C VIRUS NON-STRUCTURAL PROTEINS
EP1071955B2 (en) 1998-04-17 2009-02-18 N.V. Innogenetics S.A. Improved immunodiagnostic assays using reducing agents
AU3714499A (en) * 1998-05-14 1999-11-29 Pasteur Merieux Serums Et Vaccins Hepatitis c virus mimotopes
US7052696B2 (en) * 1998-07-10 2006-05-30 The United States Of America As Represented By The Department Of Health And Human Services Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins
US6379903B1 (en) * 1999-10-08 2002-04-30 Sigma-Aldrich Co. Purification of recombinant proteins fused to multiple epitopes
AU1236801A (en) 1999-10-27 2001-05-08 Chiron Corporation Activation of hcv-specific t cells
MXPA02006554A (es) * 1999-12-28 2003-09-22 Epimmune Inc Minigenes optimizados y peptidos codificados por los mismos.
EP1829891B1 (en) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immunoassays for Anti-HCV Antibodies
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
DE60125240T3 (de) * 2000-06-15 2010-10-28 Novartis Vaccines and Diagnostics, Inc., Emeryville Hcv-antigen/antikörper-kombinations-assay
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
CA2498228C (en) 2002-09-09 2011-03-22 Chiron Corporation Hcv assay
EP1576125A4 (en) * 2002-10-25 2008-09-03 Novartis Vaccines & Diagnostic ACTIVATION OF SPECIFIC HCV LYMPHOCYTES
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
US7871625B2 (en) 2004-08-27 2011-01-18 Novartis Vaccines And Diagnostics, Inc. HCV multiple epitope fusion antigens with modified proteolytic cleavage sites and uses thereof
JP5475279B2 (ja) * 2005-06-17 2014-04-16 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ Ｃ型肝炎ウイルス核酸ワクチン
JP5215865B2 (ja) 2005-11-22 2013-06-19 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド ノロウイルス抗原およびサポウイルス抗原
EP2244695A1 (en) 2007-12-07 2010-11-03 Novartis AG Compositions for inducing immune responses
JP6069212B2 (ja) 2010-12-02 2017-02-01 ビオノール イミュノ エーエスＢｉｏｎｏｒ Ｉｍｍｕｎｏ Ａｓ ペプチド骨格設計
JP6294076B2 (ja) 2011-01-06 2018-03-14 ビオノール イミュノ エーエスＢｉｏｎｏｒ Ｉｍｍｕｎｏ Ａｓ 多量体ペプチド
EP2806890A4 (en) * 2012-01-26 2015-09-02 Longhorn Vaccines & Diagnostics Llc COMPOSITIONAL ANTIGEN SEQUENCES AND VACCINES
KR20150018870A (ko) 2012-06-06 2015-02-24 바이오노르 이뮤노 에이에스 면역원 및 투여 반응제로서 사용하기 위한 바이러스 단백질로부터 유래하는 펩타이드
US11867696B2 (en) 2015-02-06 2024-01-09 Cell Idx, Inc. Antigen-coupled immunoreagents
BR112017020539B8 (pt) 2015-03-27 2024-01-09 Grifols Worldwide Operations Ltd Reagente para imunoensaio compreendendo um polipeptídeo, métodos de detecção de anticorpos e/ou antígenos para o vírus da hepatite c em uma amostra biológica, de seleção de amostras biológicas de um suprimento de amostras biológicas humanas, bem como polipeptídeo isolado e kit para teste imunodiagnóstico
WO2018017606A1 (en) * 2016-07-18 2018-01-25 Cell Idx, Inc. Antigen-coupled hybridization reagents
KR101813586B1 (ko) * 2016-12-29 2018-01-30 고려대학교 산학협력단 다양한 질병마커 인지 에피토프와 연결된 단백질 나노입자 및 이를 이용한 고민감도 질병마커 검출방법
CN110996986B (zh) * 2017-07-27 2024-07-19 豪夫迈·罗氏有限公司 Hcv抗原的多表位融合蛋白及其用途
KR101871985B1 (ko) * 2017-08-14 2018-06-27 고려대학교 산학협력단 3차원 단백질 나노입자 프로브 기반 복수 질환의 동시검출 방법 및 키트
CN108794636B (zh) * 2018-06-28 2020-05-22 中国人民解放军军事科学院军事医学研究院 一种表位多肽串联混合物在抗立氏立克次体的免疫保护中的应用
KR102100813B1 (ko) * 2018-11-08 2020-04-16 주식회사 보레다바이오텍 C형 간염바이러스 유래 융합 단백질 및 이를 포함하는 진단키트

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227547B1 (en) * 1991-06-24 2011-08-29 Novartis Vaccines & Diagnostic Hepatitis c virus (hcv) polypeptides
EP0610335B1 (en) * 1991-10-16 2008-01-02 Merck Patent GmbH Methods for designing recombitope peptides
US5683695A (en) * 1993-02-10 1997-11-04 United Biomedical, Inc. Production of recombinant proteins containing multiple antigenic determinants linked by flexible hinge domains
US5744144A (en) * 1993-07-30 1998-04-28 University Of Pittsburgh University Patent Committee Policy And Procedures Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
GB2294047A (en) * 1994-10-14 1996-04-17 Merck & Co Inc Synthetic peptides for use as epitopes specific for HIV

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