JP2001500723A5 - - Google Patents

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Publication number
JP2001500723A5
JP2001500723A5 JP1997542848A JP54284897A JP2001500723A5 JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5 JP 1997542848 A JP1997542848 A JP 1997542848A JP 54284897 A JP54284897 A JP 54284897A JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997542848A
Other languages
English (en)
Japanese (ja)
Other versions
JP3945822B2 (ja
JP2001500723A (ja
Filing date
Publication date
Priority claimed from US08/653,226 external-priority patent/US6514731B1/en
Application filed filed Critical
Priority claimed from PCT/US1997/008950 external-priority patent/WO1997044469A2/en
Publication of JP2001500723A publication Critical patent/JP2001500723A/ja
Publication of JP2001500723A5 publication Critical patent/JP2001500723A5/ja
Application granted granted Critical
Publication of JP3945822B2 publication Critical patent/JP3945822B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP54284897A 1996-05-24 1997-05-23 複数エピトープ融合タンパク質 Expired - Lifetime JP3945822B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/653,226 US6514731B1 (en) 1996-05-24 1996-05-24 Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
US08/653,226 1996-05-24
US08/859,524 US6428792B1 (en) 1996-05-24 1997-05-20 Hepatitis C virus multiple copy epitope fusion antigens
US08/859,524 1997-05-20
PCT/US1997/008950 WO1997044469A2 (en) 1996-05-24 1997-05-23 Multiple epitope fusion protein

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007027374A Division JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Publications (3)

Publication Number Publication Date
JP2001500723A JP2001500723A (ja) 2001-01-23
JP2001500723A5 true JP2001500723A5 (enExample) 2005-01-13
JP3945822B2 JP3945822B2 (ja) 2007-07-18

Family

ID=27096474

Family Applications (2)

Application Number Title Priority Date Filing Date
JP54284897A Expired - Lifetime JP3945822B2 (ja) 1996-05-24 1997-05-23 複数エピトープ融合タンパク質
JP2007027374A Withdrawn JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007027374A Withdrawn JP2007127671A (ja) 1996-05-24 2007-02-06 複数エピトープ融合タンパク質

Country Status (11)

Country Link
EP (1) EP0935662B1 (enExample)
JP (2) JP3945822B2 (enExample)
AT (1) ATE311463T1 (enExample)
AU (1) AU719929B2 (enExample)
CA (1) CA2250723C (enExample)
DE (1) DE69734776T2 (enExample)
DK (1) DK0935662T3 (enExample)
ES (1) ES2251028T3 (enExample)
IL (1) IL126460A (enExample)
NZ (1) NZ333431A (enExample)
WO (1) WO1997044469A2 (enExample)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6322965B1 (en) * 1997-02-10 2001-11-27 Advanced Life Science Institute, Inc. Chimera antigen peptide
WO1999015898A1 (en) * 1997-09-22 1999-04-01 Chiron Corporation Method for detecting antibodies in a sample
JP4427182B2 (ja) 1997-09-22 2010-03-03 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド 抗原を安定化するための緩衝液
KR20060057653A (ko) * 1998-01-30 2006-05-26 더 제너럴 하스피탈 코포레이션 C형 간염 바이러스의 비구조 단백질을 이용한 유전자면역법
DE69939132D1 (de) 1998-04-17 2008-08-28 Innogenetics Nv Verfahren zur Verbesserung der Proteinkonformation mit Hilfe von Reduktionsmitteln
AU3714499A (en) * 1998-05-14 1999-11-29 Pasteur Merieux Serums Et Vaccins Hepatitis c virus mimotopes
US7052696B2 (en) * 1998-07-10 2006-05-30 The United States Of America As Represented By The Department Of Health And Human Services Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins
US6379903B1 (en) * 1999-10-08 2002-04-30 Sigma-Aldrich Co. Purification of recombinant proteins fused to multiple epitopes
US6562346B1 (en) 1999-10-27 2003-05-13 Chiron Corporation Activation of HCV-specific T cells
CA2394748A1 (en) * 1999-12-28 2001-07-05 Epimmune Inc. Optimized minigenes and peptides encoded thereby
US7491808B2 (en) 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
ATE368221T1 (de) * 2000-06-15 2007-08-15 Novartis Vaccines & Diagnostic Immunoassays für anti-hcv-antikörper
EP1829891B1 (en) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immunoassays for Anti-HCV Antibodies
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
BR0314166B8 (pt) 2002-09-09 2021-07-27 Chiron Corp teste de hcv
WO2004039950A2 (en) * 2002-10-25 2004-05-13 Chiron Corporation Activation of hcv-specific cells
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
ES2377978T3 (es) 2004-08-27 2012-04-03 Novartis Vaccines And Diagnostics, Inc. Mutantes de proteínas no estructurales de VHC y usos de los mismos
EP1893636A2 (en) * 2005-06-17 2008-03-05 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Hepatitis c virus nucleic acid vaccine
WO2007081447A2 (en) 2005-11-22 2007-07-19 Novartis Vaccines And Diagnostics, Inc. Norovirus and sapovirus antigens
EP3067048B1 (en) 2007-12-07 2018-02-14 GlaxoSmithKline Biologicals SA Compositions for inducing immune responses
CN103282375B (zh) 2010-12-02 2017-01-11 比奥诺尔免疫有限公司 肽支架设计
BR112013017488A2 (pt) 2011-01-06 2017-08-01 Bionor Immuno As peptídeos imunogênicos multiméricos e monoméricos
EP3494989B1 (en) * 2012-01-26 2025-07-16 Longhorn Vaccines and Diagnostics, LLC Composite antigenic sequences and vaccines
CA2874923C (en) 2012-06-06 2021-08-31 Bionor Immuno As Peptides derived from viral proteins for use as immunogens and dosage reactants
EP3253788A4 (en) 2015-02-06 2018-08-08 Cell IDX, Inc. Antigen-coupled immunoreagents
CN107735499B (zh) 2015-03-27 2022-05-03 奥索临床诊断有限公司 Hcv ns4a/经修饰的ns3多肽及其用途
AU2017298299A1 (en) * 2016-07-18 2019-02-28 Cell Idx, Inc. Antigen-coupled hybridization reagents
KR101813586B1 (ko) * 2016-12-29 2018-01-30 고려대학교 산학협력단 다양한 질병마커 인지 에피토프와 연결된 단백질 나노입자 및 이를 이용한 고민감도 질병마커 검출방법
JP7389740B2 (ja) * 2017-07-27 2023-11-30 エフ. ホフマン-ラ ロシュ アーゲー Hcv抗原のマルチエピトープ融合タンパク質およびその使用
KR101871985B1 (ko) * 2017-08-14 2018-06-27 고려대학교 산학협력단 3차원 단백질 나노입자 프로브 기반 복수 질환의 동시검출 방법 및 키트
CN108794636B (zh) * 2018-06-28 2020-05-22 中国人民解放军军事科学院军事医学研究院 一种表位多肽串联混合物在抗立氏立克次体的免疫保护中的应用
KR102100813B1 (ko) * 2018-11-08 2020-04-16 주식회사 보레다바이오텍 C형 간염바이러스 유래 융합 단백질 및 이를 포함하는 진단키트

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2188583T3 (es) * 1991-06-24 2003-07-01 Chiron Corp Polipeptidos para el virus de la hepatitis c (hcv).
ES2300100T3 (es) * 1991-10-16 2008-06-01 Merck Patent Gmbh Metodos para el diseño de peptidos de epitodo recombinado.
US5683695A (en) * 1993-02-10 1997-11-04 United Biomedical, Inc. Production of recombinant proteins containing multiple antigenic determinants linked by flexible hinge domains
US5744144A (en) * 1993-07-30 1998-04-28 University Of Pittsburgh University Patent Committee Policy And Procedures Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof
GB2294047A (en) * 1994-10-14 1996-04-17 Merck & Co Inc Synthetic peptides for use as epitopes specific for HIV

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