JP2001500723A5 - - Google Patents
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- Publication number
- JP2001500723A5 JP2001500723A5 JP1997542848A JP54284897A JP2001500723A5 JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5 JP 1997542848 A JP1997542848 A JP 1997542848A JP 54284897 A JP54284897 A JP 54284897A JP 2001500723 A5 JP2001500723 A5 JP 2001500723A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/653,226 US6514731B1 (en) | 1996-05-24 | 1996-05-24 | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
| US08/653,226 | 1996-05-24 | ||
| US08/859,524 US6428792B1 (en) | 1996-05-24 | 1997-05-20 | Hepatitis C virus multiple copy epitope fusion antigens |
| US08/859,524 | 1997-05-20 | ||
| PCT/US1997/008950 WO1997044469A2 (en) | 1996-05-24 | 1997-05-23 | Multiple epitope fusion protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007027374A Division JP2007127671A (ja) | 1996-05-24 | 2007-02-06 | 複数エピトープ融合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001500723A JP2001500723A (ja) | 2001-01-23 |
| JP2001500723A5 true JP2001500723A5 (enExample) | 2005-01-13 |
| JP3945822B2 JP3945822B2 (ja) | 2007-07-18 |
Family
ID=27096474
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54284897A Expired - Lifetime JP3945822B2 (ja) | 1996-05-24 | 1997-05-23 | 複数エピトープ融合タンパク質 |
| JP2007027374A Withdrawn JP2007127671A (ja) | 1996-05-24 | 2007-02-06 | 複数エピトープ融合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007027374A Withdrawn JP2007127671A (ja) | 1996-05-24 | 2007-02-06 | 複数エピトープ融合タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0935662B1 (enExample) |
| JP (2) | JP3945822B2 (enExample) |
| AT (1) | ATE311463T1 (enExample) |
| AU (1) | AU719929B2 (enExample) |
| CA (1) | CA2250723C (enExample) |
| DE (1) | DE69734776T2 (enExample) |
| DK (1) | DK0935662T3 (enExample) |
| ES (1) | ES2251028T3 (enExample) |
| IL (1) | IL126460A (enExample) |
| NZ (1) | NZ333431A (enExample) |
| WO (1) | WO1997044469A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6322965B1 (en) * | 1997-02-10 | 2001-11-27 | Advanced Life Science Institute, Inc. | Chimera antigen peptide |
| WO1999015898A1 (en) * | 1997-09-22 | 1999-04-01 | Chiron Corporation | Method for detecting antibodies in a sample |
| JP4427182B2 (ja) | 1997-09-22 | 2010-03-03 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 抗原を安定化するための緩衝液 |
| KR20060057653A (ko) * | 1998-01-30 | 2006-05-26 | 더 제너럴 하스피탈 코포레이션 | C형 간염 바이러스의 비구조 단백질을 이용한 유전자면역법 |
| DE69939132D1 (de) | 1998-04-17 | 2008-08-28 | Innogenetics Nv | Verfahren zur Verbesserung der Proteinkonformation mit Hilfe von Reduktionsmitteln |
| AU3714499A (en) * | 1998-05-14 | 1999-11-29 | Pasteur Merieux Serums Et Vaccins | Hepatitis c virus mimotopes |
| US7052696B2 (en) * | 1998-07-10 | 2006-05-30 | The United States Of America As Represented By The Department Of Health And Human Services | Antigenic epitopes and mosaic polypeptides of hepatitis C virus proteins |
| US6379903B1 (en) * | 1999-10-08 | 2002-04-30 | Sigma-Aldrich Co. | Purification of recombinant proteins fused to multiple epitopes |
| US6562346B1 (en) | 1999-10-27 | 2003-05-13 | Chiron Corporation | Activation of HCV-specific T cells |
| CA2394748A1 (en) * | 1999-12-28 | 2001-07-05 | Epimmune Inc. | Optimized minigenes and peptides encoded thereby |
| US7491808B2 (en) | 2000-06-15 | 2009-02-17 | Novartis Vaccines And Diagnostics, Inc. | HCV non-structural protein mutants and uses thereof |
| ATE368221T1 (de) * | 2000-06-15 | 2007-08-15 | Novartis Vaccines & Diagnostic | Immunoassays für anti-hcv-antikörper |
| EP1829891B1 (en) | 2000-06-15 | 2012-12-26 | Novartis Vaccines and Diagnostics, Inc. | Immunoassays for Anti-HCV Antibodies |
| WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
| AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| BR0314166B8 (pt) | 2002-09-09 | 2021-07-27 | Chiron Corp | teste de hcv |
| WO2004039950A2 (en) * | 2002-10-25 | 2004-05-13 | Chiron Corporation | Activation of hcv-specific cells |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| ES2377978T3 (es) | 2004-08-27 | 2012-04-03 | Novartis Vaccines And Diagnostics, Inc. | Mutantes de proteínas no estructurales de VHC y usos de los mismos |
| EP1893636A2 (en) * | 2005-06-17 | 2008-03-05 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus nucleic acid vaccine |
| WO2007081447A2 (en) | 2005-11-22 | 2007-07-19 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and sapovirus antigens |
| EP3067048B1 (en) | 2007-12-07 | 2018-02-14 | GlaxoSmithKline Biologicals SA | Compositions for inducing immune responses |
| CN103282375B (zh) | 2010-12-02 | 2017-01-11 | 比奥诺尔免疫有限公司 | 肽支架设计 |
| BR112013017488A2 (pt) | 2011-01-06 | 2017-08-01 | Bionor Immuno As | peptídeos imunogênicos multiméricos e monoméricos |
| EP3494989B1 (en) * | 2012-01-26 | 2025-07-16 | Longhorn Vaccines and Diagnostics, LLC | Composite antigenic sequences and vaccines |
| CA2874923C (en) | 2012-06-06 | 2021-08-31 | Bionor Immuno As | Peptides derived from viral proteins for use as immunogens and dosage reactants |
| EP3253788A4 (en) | 2015-02-06 | 2018-08-08 | Cell IDX, Inc. | Antigen-coupled immunoreagents |
| CN107735499B (zh) | 2015-03-27 | 2022-05-03 | 奥索临床诊断有限公司 | Hcv ns4a/经修饰的ns3多肽及其用途 |
| AU2017298299A1 (en) * | 2016-07-18 | 2019-02-28 | Cell Idx, Inc. | Antigen-coupled hybridization reagents |
| KR101813586B1 (ko) * | 2016-12-29 | 2018-01-30 | 고려대학교 산학협력단 | 다양한 질병마커 인지 에피토프와 연결된 단백질 나노입자 및 이를 이용한 고민감도 질병마커 검출방법 |
| JP7389740B2 (ja) * | 2017-07-27 | 2023-11-30 | エフ. ホフマン-ラ ロシュ アーゲー | Hcv抗原のマルチエピトープ融合タンパク質およびその使用 |
| KR101871985B1 (ko) * | 2017-08-14 | 2018-06-27 | 고려대학교 산학협력단 | 3차원 단백질 나노입자 프로브 기반 복수 질환의 동시검출 방법 및 키트 |
| CN108794636B (zh) * | 2018-06-28 | 2020-05-22 | 中国人民解放军军事科学院军事医学研究院 | 一种表位多肽串联混合物在抗立氏立克次体的免疫保护中的应用 |
| KR102100813B1 (ko) * | 2018-11-08 | 2020-04-16 | 주식회사 보레다바이오텍 | C형 간염바이러스 유래 융합 단백질 및 이를 포함하는 진단키트 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2188583T3 (es) * | 1991-06-24 | 2003-07-01 | Chiron Corp | Polipeptidos para el virus de la hepatitis c (hcv). |
| ES2300100T3 (es) * | 1991-10-16 | 2008-06-01 | Merck Patent Gmbh | Metodos para el diseño de peptidos de epitodo recombinado. |
| US5683695A (en) * | 1993-02-10 | 1997-11-04 | United Biomedical, Inc. | Production of recombinant proteins containing multiple antigenic determinants linked by flexible hinge domains |
| US5744144A (en) * | 1993-07-30 | 1998-04-28 | University Of Pittsburgh University Patent Committee Policy And Procedures | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| GB2294047A (en) * | 1994-10-14 | 1996-04-17 | Merck & Co Inc | Synthetic peptides for use as epitopes specific for HIV |
-
1997
- 1997-05-23 WO PCT/US1997/008950 patent/WO1997044469A2/en not_active Ceased
- 1997-05-23 AU AU32143/97A patent/AU719929B2/en not_active Expired
- 1997-05-23 AT AT97927767T patent/ATE311463T1/de active
- 1997-05-23 IL IL126460A patent/IL126460A/en not_active IP Right Cessation
- 1997-05-23 NZ NZ333431A patent/NZ333431A/xx not_active IP Right Cessation
- 1997-05-23 DE DE69734776T patent/DE69734776T2/de not_active Expired - Lifetime
- 1997-05-23 DK DK97927767T patent/DK0935662T3/da active
- 1997-05-23 CA CA2250723A patent/CA2250723C/en not_active Expired - Lifetime
- 1997-05-23 ES ES97927767T patent/ES2251028T3/es not_active Expired - Lifetime
- 1997-05-23 JP JP54284897A patent/JP3945822B2/ja not_active Expired - Lifetime
- 1997-05-23 EP EP97927767A patent/EP0935662B1/en not_active Expired - Lifetime
-
2007
- 2007-02-06 JP JP2007027374A patent/JP2007127671A/ja not_active Withdrawn