|
WO1998041229A1
(en)
*
|
1997-03-19 |
1998-09-24 |
F. Hoffmann-La Roche Ag |
USE OF IL-12p40 AS IMMUNOSTIMULANT
|
|
ES2590912T3
(es)
|
1997-12-08 |
2016-11-24 |
Merck Patent Gmbh |
Proteínas de fusión heterodiméricas útiles para inmunoterapia dirigida y estimulación general del sistema inmunitario
|
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
|
MXPA00010070A
(es)
*
|
1998-04-15 |
2004-03-10 |
Lexigen Pharm Corp |
Mejora de respuestas inmunes medidas de proteina de fusion anticuerpo-citoquina por co-administracion con inhibidor de angiogenesis.
|
|
JP2002524530A
(ja)
*
|
1998-09-15 |
2002-08-06 |
ジェネティックス・インスチチュート・インコーポレーテッド |
Ｉｌ−１２を用いるカポジ肉腫の治療
|
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
|
JP4793971B2
(ja)
|
1999-08-09 |
2011-10-12 |
メルク パテント ゲーエムベーハー |
複合サイトカイン−抗体複合体
|
|
US20030190305A1
(en)
*
|
1999-09-15 |
2003-10-09 |
Wyeth And National Institutes Of Health |
Treatment of Kaposi's sarcoma with IL-12
|
|
US7074210B2
(en)
*
|
1999-10-11 |
2006-07-11 |
Felton International, Inc. |
Universal protector cap with auto-disable features for needle-free injectors
|
|
US6626871B1
(en)
|
1999-10-11 |
2003-09-30 |
Felton International, Inc. |
Method and apparatus for removing cap from medical device
|
|
EP1142590B8
(en)
*
|
1999-10-29 |
2008-11-26 |
AnGes MG, Inc. |
Gene therapy for diabetic ischemic disease
|
|
EP1228214A2
(en)
|
1999-11-12 |
2002-08-07 |
MERCK PATENT GmbH |
Erythropoietin forms with improved properties
|
|
US7887506B1
(en)
|
1999-11-23 |
2011-02-15 |
Pulse Needlefree Systems, Inc. |
Safety mechanism to prevent accidental patient injection and methods of same
|
|
US6770054B1
(en)
|
1999-11-23 |
2004-08-03 |
Felton International, Inc. |
Injector assembly with driving means and locking means
|
|
US7115712B1
(en)
|
1999-12-02 |
2006-10-03 |
Maxygen, Inc. |
Cytokine polypeptides
|
|
ATE336514T1
(de)
*
|
2000-02-11 |
2006-09-15 |
Merck Patent Gmbh |
Steigerung der zirkulierenden halbwertzeit von auf antikörpern basierenden fusionsproteinen
|
|
US20020120228A1
(en)
*
|
2000-06-08 |
2002-08-29 |
Yuh-Fun Maa |
Powder compositions
|
|
US20040213798A1
(en)
*
|
2000-06-08 |
2004-10-28 |
Powderject Vaccines, Inc. |
Spray-dried alum compositions
|
|
RU2272644C2
(ru)
*
|
2000-06-29 |
2006-03-27 |
Мерк Патент Гмбх |
Усиление иммунной реакции, медиатором которой является слитый протеин антитело-цитокин, при помощи комбинированного лечения агентами, увеличивающими поглощение иммуноцитокина
|
|
US7255865B2
(en)
*
|
2000-12-05 |
2007-08-14 |
Allergan, Inc. |
Methods of administering botulinum toxin
|
|
US20020086036A1
(en)
|
2000-12-05 |
2002-07-04 |
Allergan Sales, Inc. |
Methods for treating hyperhidrosis
|
|
DK1366067T3
(da)
*
|
2001-03-07 |
2012-10-22 |
Merck Patent Gmbh |
Ekspressionsteknologi for proteiner indeholdende en hybrid isotype-antistof-enhed
|
|
US6992174B2
(en)
*
|
2001-03-30 |
2006-01-31 |
Emd Lexigen Research Center Corp. |
Reducing the immunogenicity of fusion proteins
|
|
US6969517B2
(en)
*
|
2001-05-03 |
2005-11-29 |
Emd Lexigen Research Center Corp. |
Recombinant tumor specific antibody and use thereof
|
|
CA2349506C
(en)
*
|
2001-06-14 |
2009-12-08 |
Duke University |
A method for selective expression of therapeutic genes by hyperthermia
|
|
BR0214650A
(pt)
|
2001-12-04 |
2005-05-03 |
Merck Patent Gmbh |
Imunocitoquinas com seletividade modulada
|
|
ATE471946T1
(de)
*
|
2002-12-17 |
2010-07-15 |
Merck Patent Gmbh |
Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
|
|
JP2007517506A
(ja)
*
|
2004-01-05 |
2007-07-05 |
イーエムディー・レキシゲン・リサーチ・センター・コーポレーション |
標的化用化合物
|
|
CA2635618C
(en)
*
|
2005-12-30 |
2015-10-06 |
Merck Patent Gesellschaft Mit Beschraekter Haftung |
Interleukin-12p40 variants with improved stability
|
|
WO2007084364A2
(en)
*
|
2006-01-13 |
2007-07-26 |
The Government Of The United States, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health |
Improved il-12 for expression in mammalian cells
|
|
NZ585190A
(en)
*
|
2007-10-08 |
2012-11-30 |
Intrexon Corp |
Engineered dendritic cells and uses for the treatment of cancer
|
|
KR101361416B1
(ko)
|
2008-10-08 |
2014-02-21 |
인트렉손 코포레이션 |
다수의 면역조절자를 발현하는 조작된 세포 및 그 용도
|
|
US8556882B2
(en)
|
2009-04-30 |
2013-10-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Inducible interleukin-12
|
|
US20110014228A1
(en)
*
|
2009-06-15 |
2011-01-20 |
New York University |
Il23 modified viral vector for recombinant vaccines and tumor treatment
|
|
ES2941411T3
(es)
|
2016-05-18 |
2023-05-22 |
Modernatx Inc |
Polinucleótidos que codifican interleucina-12 (IL12) y usos de los mismos
|
|
JP7285220B2
(ja)
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン－１２（ｉｌ１２）ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|