JP2000507950A5 - - Google Patents
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- Publication number
- JP2000507950A5 JP2000507950A5 JP1997534907A JP53490797A JP2000507950A5 JP 2000507950 A5 JP2000507950 A5 JP 2000507950A5 JP 1997534907 A JP1997534907 A JP 1997534907A JP 53490797 A JP53490797 A JP 53490797A JP 2000507950 A5 JP2000507950 A5 JP 2000507950A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9606508.1A GB9606508D0 (en) | 1996-03-28 | 1996-03-28 | Chemical componds |
| GB9606508.1 | 1996-03-28 | ||
| GBGB9623001.6A GB9623001D0 (en) | 1996-11-05 | 1996-11-05 | Chemical compounds |
| GB9623001.6 | 1996-11-05 | ||
| PCT/EP1997/001530 WO1997036903A1 (en) | 1996-03-28 | 1997-03-26 | Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000507950A JP2000507950A (ja) | 2000-06-27 |
| JP2000507950A5 true JP2000507950A5 (Direct) | 2006-02-02 |
| JP4118337B2 JP4118337B2 (ja) | 2008-07-16 |
Family
ID=26309008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53490797A Expired - Fee Related JP4118337B2 (ja) | 1996-03-28 | 1997-03-26 | 好中球エラスターゼのインヒビターとしてのピロロピロロン誘導体 |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US5994344A (Direct) |
| EP (1) | EP0891362B1 (Direct) |
| JP (1) | JP4118337B2 (Direct) |
| KR (1) | KR20000005039A (Direct) |
| CN (1) | CN1067075C (Direct) |
| AP (1) | AP823A (Direct) |
| AR (1) | AR006401A1 (Direct) |
| AT (1) | ATE261969T1 (Direct) |
| AU (1) | AU726649B2 (Direct) |
| BR (1) | BR9708449A (Direct) |
| CA (1) | CA2250209A1 (Direct) |
| CO (1) | CO4790152A1 (Direct) |
| CZ (1) | CZ309798A3 (Direct) |
| DE (1) | DE69728139T2 (Direct) |
| DK (1) | DK0891362T3 (Direct) |
| EA (1) | EA001437B1 (Direct) |
| EE (1) | EE9800335A (Direct) |
| ES (1) | ES2217404T3 (Direct) |
| HU (1) | HUP9900567A3 (Direct) |
| IL (1) | IL125859A0 (Direct) |
| IS (1) | IS4837A (Direct) |
| NO (1) | NO984470L (Direct) |
| NZ (1) | NZ331490A (Direct) |
| PE (1) | PE55298A1 (Direct) |
| PL (1) | PL329153A1 (Direct) |
| PT (1) | PT891362E (Direct) |
| SK (1) | SK132498A3 (Direct) |
| TR (1) | TR199801935T2 (Direct) |
| WO (1) | WO1997036903A1 (Direct) |
| YU (1) | YU41198A (Direct) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9719189D0 (en) * | 1997-09-09 | 1997-11-12 | Glaxo Group Ltd | New therapeutic method |
| PE107899A1 (es) * | 1997-09-09 | 1999-11-17 | Glaxo Group Ltd | Derivados de pirrolopirrolona como inhibidores de elastasa leucocitaria |
| GB9719187D0 (en) * | 1997-09-09 | 1997-11-12 | Glaxo Group Ltd | Compounds |
| GB9719172D0 (en) | 1997-09-09 | 1997-11-12 | Glaxo Group Ltd | Compounds |
| GB9821199D0 (en) * | 1998-09-30 | 1998-11-25 | Glaxo Group Ltd | Chemical compounds |
| GB9905418D0 (en) * | 1999-03-09 | 1999-05-05 | Glaxo Group Ltd | Process |
| WO2004081015A1 (en) * | 2003-03-10 | 2004-09-23 | Hetero Drugs Limited | Amorphous clopidogrel hydrogen sulfate |
| MXPA05009771A (es) | 2003-03-14 | 2005-10-26 | Ono Pharmaceutical Co | Derivados heterociclicos que contienen nitrogeno y medicamentos que los contienen como el ingrediente activo. |
| US8530509B2 (en) | 2003-06-20 | 2013-09-10 | Siga Technologies, Inc. | Compounds, compositions and methods for treatment and prevention of orthopoxvirus infections and associated diseases |
| GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| US7692037B2 (en) * | 2004-09-02 | 2010-04-06 | Eastman Chemical Company | Optimized liquid-phase oxidation |
| SG146673A1 (en) | 2004-09-13 | 2008-10-30 | Ono Pharmaceutical Co | Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient |
| GB0512238D0 (en) * | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| WO2007105637A1 (ja) | 2006-03-10 | 2007-09-20 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
| CN104758281A (zh) * | 2007-04-23 | 2015-07-08 | 西佳技术公司 | 用于治疗和预防正痘病毒感染和相关疾病的化合物、组合物和方法 |
| MX2010005298A (es) | 2007-11-16 | 2010-06-30 | Rigel Pharmaceuticals Inc | Compuestos de carboxamida, sulfonamida y amina para trastornos metabolicos. |
| EP2231666B1 (en) | 2007-12-12 | 2015-07-29 | Rigel Pharmaceuticals, Inc. | Carboxamide, sulfonamide and amine compounds for metabolic disorders |
| CN112079769A (zh) | 2008-04-23 | 2020-12-15 | 里格尔药品股份有限公司 | 用于治疗代谢障碍的甲酰胺化合物 |
| AU2013363783B2 (en) * | 2012-12-18 | 2018-02-08 | Chiesi Farmaceutici S.P.A. | Novel compounds |
| JP7672641B2 (ja) | 2019-09-17 | 2025-05-08 | メレオ バイオファーマ ４ リミテッド | 移植片拒絶反応、閉塞性細気管支炎症候群、及び移植片対宿主病の治療に使用するためのアルベレスタット |
| MX2022012942A (es) | 2020-04-16 | 2023-01-11 | Mereo Biopharma 4 Ltd | Metodos que involucran el inhibidor de la elastasa de neutrofilo alvelestat para el tratamiento de enfermedades respiratorias mediadas por deficiencia de alfa-1 antitripsina. |
| IL312002A (en) | 2021-10-20 | 2024-06-01 | Mereo Biopharma 4 Ltd | Neutrophil elastase inhibitors for use in the treatment of fibrosis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2932650A (en) * | 1957-11-19 | 1960-04-12 | Arthur C Cope | 2-6-diazabicyclo (3. 3. 0) octanes |
| US4997950A (en) * | 1989-04-20 | 1991-03-05 | Richard Finbar Murphy | Novel C-terminal gastrin antagonists |
| GB9211783D0 (en) * | 1992-06-04 | 1992-07-15 | Ici Plc | Amide derivatives |
| GB9402680D0 (en) * | 1994-02-11 | 1994-04-06 | Zeneca Ltd | Pyrrolidine derivatives |
| US5610296A (en) * | 1994-12-05 | 1997-03-11 | G. D. Searle & Co. | Process for the preparation of amidino phenyl pyrrolidine beta-alanine urea analogs |
-
1997
- 1997-03-26 AR ARP970101212A patent/AR006401A1/es not_active Application Discontinuation
- 1997-03-26 AT AT97915439T patent/ATE261969T1/de not_active IP Right Cessation
- 1997-03-26 PL PL97329153A patent/PL329153A1/xx unknown
- 1997-03-26 WO PCT/EP1997/001530 patent/WO1997036903A1/en not_active Ceased
- 1997-03-26 PE PE1997000244A patent/PE55298A1/es not_active Application Discontinuation
- 1997-03-26 SK SK1324-98A patent/SK132498A3/sk unknown
- 1997-03-26 CA CA002250209A patent/CA2250209A1/en not_active Abandoned
- 1997-03-26 EP EP97915439A patent/EP0891362B1/en not_active Expired - Lifetime
- 1997-03-26 DK DK97915439T patent/DK0891362T3/da active
- 1997-03-26 KR KR1019980707664A patent/KR20000005039A/ko not_active Withdrawn
- 1997-03-26 EE EE9800335A patent/EE9800335A/xx unknown
- 1997-03-26 ES ES97915439T patent/ES2217404T3/es not_active Expired - Lifetime
- 1997-03-26 NZ NZ331490A patent/NZ331490A/en unknown
- 1997-03-26 US US09/155,323 patent/US5994344A/en not_active Expired - Fee Related
- 1997-03-26 EA EA199800773A patent/EA001437B1/ru not_active IP Right Cessation
- 1997-03-26 TR TR1998/01935T patent/TR199801935T2/xx unknown
- 1997-03-26 AU AU22917/97A patent/AU726649B2/en not_active Ceased
- 1997-03-26 AP APAP/P/1998/001351A patent/AP823A/en active
- 1997-03-26 BR BR9708449A patent/BR9708449A/pt unknown
- 1997-03-26 CZ CZ983097A patent/CZ309798A3/cs unknown
- 1997-03-26 CN CN97194959A patent/CN1067075C/zh not_active Expired - Lifetime
- 1997-03-26 IL IL12585997A patent/IL125859A0/xx unknown
- 1997-03-26 HU HU9900567A patent/HUP9900567A3/hu unknown
- 1997-03-26 PT PT97915439T patent/PT891362E/pt unknown
- 1997-03-26 JP JP53490797A patent/JP4118337B2/ja not_active Expired - Fee Related
- 1997-03-26 DE DE69728139T patent/DE69728139T2/de not_active Expired - Fee Related
- 1997-03-31 CO CO97015902A patent/CO4790152A1/es unknown
-
1998
- 1998-08-28 IS IS4837A patent/IS4837A/is unknown
- 1998-09-23 YU YU41198A patent/YU41198A/sh unknown
- 1998-09-25 NO NO984470A patent/NO984470L/no not_active Application Discontinuation
-
1999
- 1999-10-15 US US09/418,644 patent/US6057457A/en not_active Expired - Fee Related
-
2000
- 2000-03-03 US US09/517,963 patent/US6215002B1/en not_active Expired - Fee Related