JO2903B1 - Salts and crystalline forms of 2-methyl-2-[4-3-methyl-2-oxo-8-quinoline-3-yl-3-yl-2, 3-dihydro-imidazo [4,5-c] quinoline -1- YL) - phenyl - propionitrile - Google Patents

Salts and crystalline forms of 2-methyl-2-[4-3-methyl-2-oxo-8-quinoline-3-yl-3-yl-2, 3-dihydro-imidazo [4,5-c] quinoline -1- YL) - phenyl - propionitrile

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Publication number
JO2903B1
JO2903B1 JO2007482A JOP20070482A JO2903B1 JO 2903 B1 JO2903 B1 JO 2903B1 JO 2007482 A JO2007482 A JO 2007482A JO P20070482 A JOP20070482 A JO P20070482A JO 2903 B1 JO2903 B1 JO 2903B1
Authority
JO
Jordan
Prior art keywords
quinolin
methyl
salts
propionitrile
imidazo
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Application number
JO2007482A
Other languages
Arabic (ar)
English (en)
Inventor
ديفيداسراو جاراد سودهاكر
ستواسير فرانك
بانزيجر ماركوس
Original Assignee
نوفارتيس ايه جي
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by نوفارتيس ايه جي filed Critical نوفارتيس ايه جي
Application granted granted Critical
Publication of JO2903B1 publication Critical patent/JO2903B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
    • C07C309/30—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings of six-membered aromatic rings substituted by alkyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JO2007482A 2006-11-20 2007-11-19 Salts and crystalline forms of 2-methyl-2-[4-3-methyl-2-oxo-8-quinoline-3-yl-3-yl-2, 3-dihydro-imidazo [4,5-c] quinoline -1- YL) - phenyl - propionitrile JO2903B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86648306P 2006-11-20 2006-11-20

Publications (1)

Publication Number Publication Date
JO2903B1 true JO2903B1 (en) 2015-09-15

Family

ID=39345299

Family Applications (1)

Application Number Title Priority Date Filing Date
JO2007482A JO2903B1 (en) 2006-11-20 2007-11-19 Salts and crystalline forms of 2-methyl-2-[4-3-methyl-2-oxo-8-quinoline-3-yl-3-yl-2, 3-dihydro-imidazo [4,5-c] quinoline -1- YL) - phenyl - propionitrile

Country Status (36)

Country Link
US (2) US8436177B2 (es)
EP (2) EP2094700B1 (es)
JP (2) JP5562033B2 (es)
KR (3) KR20090080530A (es)
CN (5) CN102993202A (es)
AR (1) AR064256A1 (es)
AU (1) AU2007323820B2 (es)
BR (1) BRPI0719112A2 (es)
CA (1) CA2669199C (es)
CL (1) CL2007003316A1 (es)
CO (1) CO6382134A2 (es)
CR (1) CR10757A (es)
DO (1) DOP2009000116A (es)
EA (1) EA015677B1 (es)
EC (1) ECSP099340A (es)
GE (1) GEP20125436B (es)
GT (1) GT200900133A (es)
HK (1) HK1132739A1 (es)
HR (1) HRP20140627T1 (es)
IL (2) IL198467A (es)
JO (1) JO2903B1 (es)
MA (1) MA30967B1 (es)
MX (1) MX2009005360A (es)
MY (1) MY150216A (es)
NI (1) NI200900091A (es)
NO (1) NO20092227L (es)
NZ (1) NZ576357A (es)
PE (2) PE20081780A1 (es)
PH (1) PH12013502100A1 (es)
RS (1) RS53335B (es)
SM (1) SMP200900041B (es)
TN (1) TN2009000191A1 (es)
TW (2) TW201402567A (es)
UA (1) UA98473C2 (es)
UY (1) UY30728A1 (es)
WO (1) WO2008064093A2 (es)

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JP6382949B2 (ja) 2013-04-17 2018-08-29 シグナル ファーマシューティカルズ，エルエルシー 癌を治療するためのｔｏｒキナーゼ阻害剤及び５−置換キナゾリノン化合物を含む組合せ療法
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Also Published As

Publication number Publication date
EP2094700A2 (en) 2009-09-02
CL2007003316A1 (es) 2008-06-27
EP2364981A1 (en) 2011-09-14
US20100168153A1 (en) 2010-07-01
HRP20140627T1 (hr) 2014-09-26
AU2007323820A1 (en) 2008-05-29
CN102993202A (zh) 2013-03-27
KR20090080530A (ko) 2009-07-24
EP2094700B1 (en) 2014-04-02
NZ576357A (en) 2011-01-28
SMAP200900041A (it) 2009-07-14
PE20120083A1 (es) 2012-03-01
JP5562033B2 (ja) 2014-07-30
IL198467A (en) 2014-11-30
CN106045993A (zh) 2016-10-26
EA015677B1 (ru) 2011-10-31
AR064256A1 (es) 2009-03-25
CA2669199C (en) 2015-12-29
PE20081780A1 (es) 2009-01-01
MA30967B1 (fr) 2009-12-01
US20130289064A1 (en) 2013-10-31
TN2009000191A1 (en) 2010-10-18
UY30728A1 (es) 2008-07-03
PH12013502100A1 (en) 2015-09-21
US8436177B2 (en) 2013-05-07
WO2008064093A3 (en) 2008-08-14
WO2008064093A2 (en) 2008-05-29
IL198467A0 (en) 2010-02-17
GT200900133A (es) 2010-05-21
CN109970735A (zh) 2019-07-05
MY150216A (en) 2013-12-13
KR20140129396A (ko) 2014-11-06
JP2010510240A (ja) 2010-04-02
JP2013173788A (ja) 2013-09-05
CN101541793A (zh) 2009-09-23
CO6382134A2 (es) 2012-02-15
BRPI0719112A2 (pt) 2013-12-10
NI200900091A (es) 2010-02-17
RS53335B (en) 2014-10-31
TW200827356A (en) 2008-07-01
UA98473C2 (ru) 2012-05-25
DOP2009000116A (es) 2009-05-31
TWI417292B (zh) 2013-12-01
ECSP099340A (es) 2009-06-30
EA200900638A1 (ru) 2009-12-30
MX2009005360A (es) 2009-06-05
KR20140091718A (ko) 2014-07-22
GEP20125436B (en) 2012-03-26
CA2669199A1 (en) 2008-05-29
CN102336752A (zh) 2012-02-01
NO20092227L (no) 2009-08-17
AU2007323820B2 (en) 2012-02-23
HK1132739A1 (en) 2010-03-05
TW201402567A (zh) 2014-01-16
SMP200900041B (it) 2009-09-07
IL219877A0 (en) 2012-06-28
CR10757A (es) 2009-06-11

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