ITUB20160413A1 - Metodo per determinare Helicobacter pylori - Google Patents

Metodo per determinare Helicobacter pylori

Info

Publication number
ITUB20160413A1
ITUB20160413A1 ITUB2016A000413A ITUB20160413A ITUB20160413A1 IT UB20160413 A1 ITUB20160413 A1 IT UB20160413A1 IT UB2016A000413 A ITUB2016A000413 A IT UB2016A000413A IT UB20160413 A ITUB20160413 A IT UB20160413A IT UB20160413 A1 ITUB20160413 A1 IT UB20160413A1
Authority
IT
Italy
Prior art keywords
helicobacter pylori
determining
determining helicobacter
pylori
helicobacter
Prior art date
Application number
ITUB2016A000413A
Other languages
English (en)
Inventor
Filippo Bastia
Original Assignee
Thd Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thd Spa filed Critical Thd Spa
Priority to ITUB2016A000413A priority Critical patent/ITUB20160413A1/it
Priority to ES17712224T priority patent/ES2882501T3/es
Priority to JP2018540864A priority patent/JP7015786B2/ja
Priority to EP17712224.9A priority patent/EP3411714B1/en
Priority to CA3013547A priority patent/CA3013547A1/en
Priority to MX2018009505A priority patent/MX2018009505A/es
Priority to PCT/IB2017/050611 priority patent/WO2017134627A1/en
Priority to BR112018015965A priority patent/BR112018015965A2/pt
Priority to RU2018130349A priority patent/RU2744190C1/ru
Priority to CN201780009847.8A priority patent/CN108884489B/zh
Priority to US16/075,425 priority patent/US11377681B2/en
Publication of ITUB20160413A1 publication Critical patent/ITUB20160413A1/it

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56922Campylobacter
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ITUB2016A000413A 2016-02-05 2016-02-05 Metodo per determinare Helicobacter pylori ITUB20160413A1 (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ITUB2016A000413A ITUB20160413A1 (it) 2016-02-05 2016-02-05 Metodo per determinare Helicobacter pylori
ES17712224T ES2882501T3 (es) 2016-02-05 2017-02-03 Método para determinar Helicobacter pylori
JP2018540864A JP7015786B2 (ja) 2016-02-05 2017-02-03 ヘリコバクター・ピロリを判定するための方法
EP17712224.9A EP3411714B1 (en) 2016-02-05 2017-02-03 Method for determining helicobacter pylori
CA3013547A CA3013547A1 (en) 2016-02-05 2017-02-03 Method for determining helicobacter pylori
MX2018009505A MX2018009505A (es) 2016-02-05 2017-02-03 Metodo para determinar helicobacter pylori.
PCT/IB2017/050611 WO2017134627A1 (en) 2016-02-05 2017-02-03 Method for determining helicobacter pylori
BR112018015965A BR112018015965A2 (pt) 2016-02-05 2017-02-03 método para determinação de helicobacter pylori
RU2018130349A RU2744190C1 (ru) 2016-02-05 2017-02-03 Способ определения Helicobacter pylori
CN201780009847.8A CN108884489B (zh) 2016-02-05 2017-02-03 用于确定幽门螺杆菌(Helicobacter pylori)的方法
US16/075,425 US11377681B2 (en) 2016-02-05 2017-02-03 Method for determining Helicobacter pylori

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2016A000413A ITUB20160413A1 (it) 2016-02-05 2016-02-05 Metodo per determinare Helicobacter pylori

Publications (1)

Publication Number Publication Date
ITUB20160413A1 true ITUB20160413A1 (it) 2017-08-05

Family

ID=55948929

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2016A000413A ITUB20160413A1 (it) 2016-02-05 2016-02-05 Metodo per determinare Helicobacter pylori

Country Status (11)

Country Link
US (1) US11377681B2 (it)
EP (1) EP3411714B1 (it)
JP (1) JP7015786B2 (it)
CN (1) CN108884489B (it)
BR (1) BR112018015965A2 (it)
CA (1) CA3013547A1 (it)
ES (1) ES2882501T3 (it)
IT (1) ITUB20160413A1 (it)
MX (1) MX2018009505A (it)
RU (1) RU2744190C1 (it)
WO (1) WO2017134627A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101979202B1 (ko) * 2017-11-01 2019-05-15 연세대학교 원주산학협력단 퀀타매트릭스 어세이 플랫폼 기반 헬리코박터 파이로리균 및 그 균의 항생제 내성에 관련된 유전자의 검출을 확인할 수 있는 진단법 및 그 응용
SG11202102098WA (en) * 2018-09-03 2021-04-29 Visby Medical Inc Devices and methods for antibiotic susceptibility testing
CN109762877B (zh) * 2019-01-21 2021-03-09 北京大学第三医院(北京大学第三临床医学院) 从粪便中富集胃幽门螺杆菌治疗相关基因的方法及试剂盒
CN109797203A (zh) * 2019-01-24 2019-05-24 杭州和壹基因科技有限公司 幽门螺杆菌检测体系及检测试剂盒和应用
EP4085149A4 (en) 2020-01-03 2024-03-06 Visby Medical Inc ANTIBIOTIC SUSCEPTIBILITY TESTING DEVICES AND METHODS
CN111304345A (zh) * 2020-02-27 2020-06-19 中国人民解放军军事科学院军事医学研究院 幽门螺旋杆菌23S rRNA基因耐药突变的检测方法及其应用
CN111455073A (zh) * 2020-03-26 2020-07-28 温州医科大学附属第一医院 幽门螺旋杆菌分型与耐药检测的扩增和测序引物及试剂盒
WO2023121098A1 (ko) * 2021-12-23 2023-06-29 주식회사 이노제닉스 피시알-리버스 블랏 교잡 어세이 기반 헬리코박터 파이로리균 및 그 균의 항생제 내성에 관련된 유전자의 동시 검출을 확인할 수 있는 개선된 진단법 및 그 응용

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WO2000029618A1 (en) * 1998-11-12 2000-05-25 University Of Virginia Patent Foundation Non-invasive detection of helicobacter pylori infection
CN101665824A (zh) * 2009-09-24 2010-03-10 周玉贵 一种检测幽门螺杆菌克拉霉素耐药基因的生物芯片及其制备方法和应用
WO2014087055A1 (en) * 2012-12-05 2014-06-12 Amplidiag Oy Method for detecting helicobacter pylori dna in a stool sample

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US6312894B1 (en) 1995-04-03 2001-11-06 Epoch Pharmaceuticals, Inc. Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
PT104744A (pt) * 2009-09-11 2011-03-11 Univ Do Minho Sondas de ácido péptido nucleico, estojo e método para detectar helicobacter pylori e/ou da sua resposta à claritromicina e respectivas aplicações

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2000029618A1 (en) * 1998-11-12 2000-05-25 University Of Virginia Patent Foundation Non-invasive detection of helicobacter pylori infection
CN101665824A (zh) * 2009-09-24 2010-03-10 周玉贵 一种检测幽门螺杆菌克拉霉素耐药基因的生物芯片及其制备方法和应用
WO2014087055A1 (en) * 2012-12-05 2014-06-12 Amplidiag Oy Method for detecting helicobacter pylori dna in a stool sample

Non-Patent Citations (6)

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Title
AKIKO NAKAMURA ET AL: "Determination of mutations of the 23S rRNA gene of Helicobacter?pylori by allele specific primer-polymerase chain reaction method", JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 22, no. 7, 1 July 2007 (2007-07-01), AU, pages 1057 - 1063, XP055288549, ISSN: 0815-9319, DOI: 10.1111/j.1440-1746.2006.04546.x *
C. SCHABEREITER-GURTNER ET AL: "Novel Real-Time PCR Assay for Detection of Helicobacter pylori Infection and Simultaneous Clarithromycin Susceptibility Testing of Stool and Biopsy Specimens", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 42, no. 10, 1 October 2004 (2004-10-01), pages 4512 - 4518, XP055098248, ISSN: 0095-1137, DOI: 10.1128/JCM.42.10.4512-4518.2004 *
ISABEL C. A. SCALETSKY ET AL: "Application of Real-Time PCR Stool Assay for Helicobacter pylori Detection and Clarithromycin Susceptibility Testing in Brazilian Children", HELICOBACTER, vol. 16, no. 4, 1 August 2011 (2011-08-01), US, pages 311 - 315, XP055288584, ISSN: 1083-4389, DOI: 10.1111/j.1523-5378.2011.00845.x *
LYUDMILA BOYANOVA ET AL: "Clarithromycin Resistance Mutations in Helicobacter pylori in Association with Virulence Factors and Antibiotic Susceptibility of the Strains", MICROBIAL DRUG RESISTANCE., vol. 22, no. 3, 30 November 2015 (2015-11-30), US, pages 227 - 232, XP055288522, ISSN: 1076-6294, DOI: 10.1089/mdr.2015.0199 *
TAKAHISA FURUTA ET AL: "Modified allele-specific primer-polymerase chain reaction method for analysis of susceptibility of Helicobacter pylori strains to clarithromycin", JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 22, no. 11, 1 November 2007 (2007-11-01), AU, pages 1810 - 1815, XP055288517, ISSN: 0815-9319, DOI: 10.1111/j.1440-1746.2007.04919.x *
YUAN LI ET AL: "Detection of clarithromycin resistance in Helicobacter pylori following noncryogenic storage of rapid urease tests for 30 days", JOURNAL OF DIGESTIVE DISEASES, vol. 13, no. 1, 21 December 2011 (2011-12-21), pages 54 - 59, XP055288524, ISSN: 1751-2972, DOI: 10.1111/j.1751-2980.2011.00549.x *

Also Published As

Publication number Publication date
JP2019506169A (ja) 2019-03-07
EP3411714A1 (en) 2018-12-12
MX2018009505A (es) 2019-05-06
US11377681B2 (en) 2022-07-05
RU2744190C1 (ru) 2021-03-03
BR112018015965A2 (pt) 2018-12-18
US20190211381A1 (en) 2019-07-11
JP7015786B2 (ja) 2022-02-03
ES2882501T3 (es) 2021-12-02
CN108884489A (zh) 2018-11-23
EP3411714B1 (en) 2021-03-24
WO2017134627A1 (en) 2017-08-10
CA3013547A1 (en) 2017-08-10
CN108884489B (zh) 2022-06-14

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