ITRM920919A0 - Nuovo preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale. - Google Patents
Nuovo preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale.Info
- Publication number
- ITRM920919A0 ITRM920919A0 IT92RM919A ITRM920919A ITRM920919A0 IT RM920919 A0 ITRM920919 A0 IT RM920919A0 IT 92RM919 A IT92RM919 A IT 92RM919A IT RM920919 A ITRM920919 A IT RM920919A IT RM920919 A0 ITRM920919 A0 IT RM920919A0
- Authority
- IT
- Italy
- Prior art keywords
- anticoagulant
- inflammatory
- anticancer activity
- new preparation
- preparation
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 229940127219 anticoagulant drug Drugs 0.000 title 1
- 230000014508 negative regulation of coagulation Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Pain & Pain Management (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920919A IT1257184B (it) | 1992-12-22 | 1992-12-22 | Preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale |
EP94904167A EP0675956B1 (en) | 1992-12-22 | 1993-12-21 | New protein from urine named component b |
US08/448,561 US5908827A (en) | 1992-12-22 | 1993-12-21 | Protein from urine named component B |
AU58335/94A AU690093B2 (en) | 1992-12-22 | 1993-12-21 | New protein from urine named component B |
ES94904167T ES2193152T3 (es) | 1992-12-22 | 1993-12-21 | Nueva proteina de la orina denominada componente b. |
CA002151156A CA2151156A1 (en) | 1992-12-22 | 1993-12-21 | New protein from urine named component b |
JP6514813A JP3025014B2 (ja) | 1992-12-22 | 1993-12-21 | 成分bと命名された新規な蛋白質 |
DE69332861T DE69332861T2 (de) | 1992-12-22 | 1993-12-21 | Neues protein aus urin, komponent b genannt |
PCT/EP1993/003645 WO1994014959A1 (en) | 1992-12-22 | 1993-12-21 | New protein from urine named component b |
UA95062918A UA46702C2 (uk) | 1992-12-22 | 1993-12-21 | Поліпептид, спосіб одержання поліпептиду (варіанти),фрагмент днк (варіанти), експресуючий вектор (варіанти), штам e.coli, лінія клітин (варіанти), білок, фармацевтична композиція (варіанти) |
DK94904167T DK0675956T3 (da) | 1992-12-22 | 1993-12-21 | Nyt protein fra urin betegnet komponent B |
AT94904167T ATE236976T1 (de) | 1992-12-22 | 1993-12-21 | Neues protein aus urin, komponent b genannt |
PT94904167T PT675956E (pt) | 1992-12-22 | 1993-12-21 | Proteina nova da urina denominada componente b |
KR1019950702407A KR100193107B1 (ko) | 1992-12-22 | 1993-12-21 | 성분b로 명명된 신규 단백질 |
RU95113418/13A RU2177480C2 (ru) | 1992-12-22 | 1993-12-22 | Полипептид, способ получения (варианты), днк (варианты), вектор (варианты), клетка, применение полипептида, фармацевтическая композиция (варианты) |
ZA939621A ZA939621B (en) | 1992-12-22 | 1993-12-22 | Protein named component B |
IL10814993A IL108149A (en) | 1992-12-22 | 1993-12-22 | Component b protein, its preparation and pharmaceutical compositions containing it |
FI953091A FI114478B (fi) | 1992-12-22 | 1995-06-21 | Menetelmä virtsasta peräisin olevan komponentti B: ksi kutsutun proteiinin valmistamiseksi |
NO19952494A NO315800B1 (no) | 1992-12-22 | 1995-06-21 | Polypeptid fra urin med betegnelse komponent B, fremgangsmate for fremstilling av dette, DNA-molekyl, ekspresjonsvektor, vertscelle, pattedyrscelle, anvendelse av polypeptidet for fremstilling av et medikament samt farmasoytisk preparat |
FI20040608A FI116059B (fi) | 1992-12-22 | 2004-04-29 | Analogiamenetelmä komponentti B:ksi kutsutun rekombinanttiproteiinin valmistamiseksi sekä DNA-molekyyli, ilmentämisvektori ja isäntäsolu |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920919A IT1257184B (it) | 1992-12-22 | 1992-12-22 | Preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM920919A0 true ITRM920919A0 (it) | 1992-12-22 |
ITRM920919A1 ITRM920919A1 (it) | 1994-06-22 |
IT1257184B IT1257184B (it) | 1996-01-10 |
Family
ID=11401349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM920919A IT1257184B (it) | 1992-12-22 | 1992-12-22 | Preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale |
Country Status (19)
Country | Link |
---|---|
US (1) | US5908827A (it) |
EP (1) | EP0675956B1 (it) |
JP (1) | JP3025014B2 (it) |
KR (1) | KR100193107B1 (it) |
AT (1) | ATE236976T1 (it) |
AU (1) | AU690093B2 (it) |
CA (1) | CA2151156A1 (it) |
DE (1) | DE69332861T2 (it) |
DK (1) | DK0675956T3 (it) |
ES (1) | ES2193152T3 (it) |
FI (2) | FI114478B (it) |
IL (1) | IL108149A (it) |
IT (1) | IT1257184B (it) |
NO (1) | NO315800B1 (it) |
PT (1) | PT675956E (it) |
RU (1) | RU2177480C2 (it) |
UA (1) | UA46702C2 (it) |
WO (1) | WO1994014959A1 (it) |
ZA (1) | ZA939621B (it) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA001077B1 (ru) * | 1996-04-24 | 2000-10-30 | Апплайд Резеч Системз Арс Холдинг Н.В. | Компонент в, используемый в качестве рубцующего агента, содержащая его фармацевтическая композиция и способ лечения |
WO1998056810A2 (de) * | 1997-06-09 | 1998-12-17 | Forssmann Wolf Georg | Humanes protein lus-i, seine herstellung und verwendung |
AU765600B2 (en) | 1998-07-09 | 2003-09-25 | Merck Serono Sa | Compound B as angiogenic agent in combination with human growth factors |
US6962700B1 (en) | 2000-09-13 | 2005-11-08 | Atopix Pharmaceuticals Corporation | Method of manufacturing immune globulin |
AU2004229237B2 (en) * | 2003-04-16 | 2009-06-04 | Merck Serono Sa | Use of SLURP-1 for treating diseases related to acetylcholine receptors dysfunction |
US7343581B2 (en) * | 2005-06-27 | 2008-03-11 | Tela Innovations, Inc. | Methods for creating primitive constructed standard cells |
US7590968B1 (en) | 2006-03-01 | 2009-09-15 | Tela Innovations, Inc. | Methods for risk-informed chip layout generation |
US8245180B2 (en) | 2006-03-09 | 2012-08-14 | Tela Innovations, Inc. | Methods for defining and using co-optimized nanopatterns for integrated circuit design and apparatus implementing same |
US8448102B2 (en) | 2006-03-09 | 2013-05-21 | Tela Innovations, Inc. | Optimizing layout of irregular structures in regular layout context |
US7908578B2 (en) | 2007-08-02 | 2011-03-15 | Tela Innovations, Inc. | Methods for designing semiconductor device with dynamic array section |
US7932545B2 (en) | 2006-03-09 | 2011-04-26 | Tela Innovations, Inc. | Semiconductor device and associated layouts including gate electrode level region having arrangement of six linear conductive segments with side-to-side spacing less than 360 nanometers |
US7956421B2 (en) | 2008-03-13 | 2011-06-07 | Tela Innovations, Inc. | Cross-coupled transistor layouts in restricted gate level layout architecture |
US9563733B2 (en) | 2009-05-06 | 2017-02-07 | Tela Innovations, Inc. | Cell circuit and layout with linear finfet structures |
US8839175B2 (en) | 2006-03-09 | 2014-09-16 | Tela Innovations, Inc. | Scalable meta-data objects |
US8541879B2 (en) | 2007-12-13 | 2013-09-24 | Tela Innovations, Inc. | Super-self-aligned contacts and method for making the same |
US8225261B2 (en) | 2006-03-09 | 2012-07-17 | Tela Innovations, Inc. | Methods for defining contact grid in dynamic array architecture |
US9035359B2 (en) | 2006-03-09 | 2015-05-19 | Tela Innovations, Inc. | Semiconductor chip including region including linear-shaped conductive structures forming gate electrodes and having electrical connection areas arranged relative to inner region between transistors of different types and associated methods |
US7446352B2 (en) | 2006-03-09 | 2008-11-04 | Tela Innovations, Inc. | Dynamic array architecture |
US8653857B2 (en) | 2006-03-09 | 2014-02-18 | Tela Innovations, Inc. | Circuitry and layouts for XOR and XNOR logic |
US8247846B2 (en) | 2006-03-09 | 2012-08-21 | Tela Innovations, Inc. | Oversized contacts and vias in semiconductor chip defined by linearly constrained topology |
US9230910B2 (en) | 2006-03-09 | 2016-01-05 | Tela Innovations, Inc. | Oversized contacts and vias in layout defined by linearly constrained topology |
US7763534B2 (en) | 2007-10-26 | 2010-07-27 | Tela Innovations, Inc. | Methods, structures and designs for self-aligning local interconnects used in integrated circuits |
US8658542B2 (en) | 2006-03-09 | 2014-02-25 | Tela Innovations, Inc. | Coarse grid design methods and structures |
US8225239B2 (en) | 2006-03-09 | 2012-07-17 | Tela Innovations, Inc. | Methods for defining and utilizing sub-resolution features in linear topology |
US9009641B2 (en) | 2006-03-09 | 2015-04-14 | Tela Innovations, Inc. | Circuits with linear finfet structures |
US7943967B2 (en) | 2006-03-09 | 2011-05-17 | Tela Innovations, Inc. | Semiconductor device and associated layouts including diffusion contact placement restriction based on relation to linear conductive segments |
US7586800B1 (en) | 2006-08-08 | 2009-09-08 | Tela Innovations, Inc. | Memory timing apparatus and associated methods |
US8286107B2 (en) | 2007-02-20 | 2012-10-09 | Tela Innovations, Inc. | Methods and systems for process compensation technique acceleration |
US7979829B2 (en) * | 2007-02-20 | 2011-07-12 | Tela Innovations, Inc. | Integrated circuit cell library with cell-level process compensation technique (PCT) application and associated methods |
US8667443B2 (en) | 2007-03-05 | 2014-03-04 | Tela Innovations, Inc. | Integrated circuit cell library for multiple patterning |
NZ583783A (en) * | 2007-09-20 | 2012-10-26 | Commw Scient Ind Res Org | Avian interferon-lambda polypeptide and genetic sequences encoding the same |
RU2486245C2 (ru) * | 2007-10-15 | 2013-06-27 | Чугаи Сейяку Кабусики Кайся | Способ получения клетки, способной продуцировать гетеропротеины с высоким выходом |
US8453094B2 (en) | 2008-01-31 | 2013-05-28 | Tela Innovations, Inc. | Enforcement of semiconductor structure regularity for localized transistors and interconnect |
US7939443B2 (en) | 2008-03-27 | 2011-05-10 | Tela Innovations, Inc. | Methods for multi-wire routing and apparatus implementing same |
KR101749351B1 (ko) | 2008-07-16 | 2017-06-20 | 텔라 이노베이션스, 인코포레이티드 | 동적 어레이 아키텍쳐에서의 셀 페이징과 배치를 위한 방법 및 그 구현 |
US9122832B2 (en) | 2008-08-01 | 2015-09-01 | Tela Innovations, Inc. | Methods for controlling microloading variation in semiconductor wafer layout and fabrication |
GB0820631D0 (en) * | 2008-11-11 | 2008-12-17 | London School Hygiene & Tropical Medicine | Vectors |
EP2239322A1 (en) * | 2009-04-07 | 2010-10-13 | Basf Se | Use of enzymes to reduce formaldehyde from formaldehyde-containing products |
US8661392B2 (en) | 2009-10-13 | 2014-02-25 | Tela Innovations, Inc. | Methods for cell boundary encroachment and layouts implementing the Same |
US9159627B2 (en) | 2010-11-12 | 2015-10-13 | Tela Innovations, Inc. | Methods for linewidth modification and apparatus implementing the same |
EP2740485B1 (en) * | 2012-12-07 | 2018-10-31 | Brightpulse Holding LTD. | Protein slurp-1 for use in the treatment of ocular diseases |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4359415A (en) * | 1981-06-03 | 1982-11-16 | University Of Tennessee Research Corporation | Isolation of an antineoplastic protein fraction and an antineoplastic peptide fraction from human urine |
US4470970A (en) * | 1981-07-02 | 1984-09-11 | Burzynski Stanislaw R | Purified antineoplaston fractions and methods of treating neoplastic disease |
US5298604A (en) * | 1992-07-27 | 1994-03-29 | Sloane Nathan H | Parital primary amino acid sequence of the antineoplastic protein (ANUP); a cytokine present in granulocytes |
-
1992
- 1992-12-22 IT ITRM920919A patent/IT1257184B/it active IP Right Grant
-
1993
- 1993-12-21 KR KR1019950702407A patent/KR100193107B1/ko not_active IP Right Cessation
- 1993-12-21 WO PCT/EP1993/003645 patent/WO1994014959A1/en active IP Right Grant
- 1993-12-21 DE DE69332861T patent/DE69332861T2/de not_active Expired - Fee Related
- 1993-12-21 UA UA95062918A patent/UA46702C2/uk unknown
- 1993-12-21 CA CA002151156A patent/CA2151156A1/en not_active Abandoned
- 1993-12-21 PT PT94904167T patent/PT675956E/pt unknown
- 1993-12-21 US US08/448,561 patent/US5908827A/en not_active Expired - Fee Related
- 1993-12-21 AT AT94904167T patent/ATE236976T1/de not_active IP Right Cessation
- 1993-12-21 EP EP94904167A patent/EP0675956B1/en not_active Expired - Lifetime
- 1993-12-21 DK DK94904167T patent/DK0675956T3/da active
- 1993-12-21 AU AU58335/94A patent/AU690093B2/en not_active Ceased
- 1993-12-21 JP JP6514813A patent/JP3025014B2/ja not_active Expired - Fee Related
- 1993-12-21 ES ES94904167T patent/ES2193152T3/es not_active Expired - Lifetime
- 1993-12-22 ZA ZA939621A patent/ZA939621B/xx unknown
- 1993-12-22 RU RU95113418/13A patent/RU2177480C2/ru not_active IP Right Cessation
- 1993-12-22 IL IL10814993A patent/IL108149A/xx not_active IP Right Cessation
-
1995
- 1995-06-21 FI FI953091A patent/FI114478B/fi active IP Right Grant
- 1995-06-21 NO NO19952494A patent/NO315800B1/no not_active IP Right Cessation
-
2004
- 2004-04-29 FI FI20040608A patent/FI116059B/fi active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JPH08509359A (ja) | 1996-10-08 |
ATE236976T1 (de) | 2003-04-15 |
UA46702C2 (uk) | 2002-06-17 |
IL108149A0 (en) | 1994-04-12 |
JP3025014B2 (ja) | 2000-03-27 |
US5908827A (en) | 1999-06-01 |
DE69332861D1 (de) | 2003-05-15 |
ZA939621B (en) | 1995-06-22 |
FI20040608A (fi) | 2004-04-29 |
FI114478B (fi) | 2004-10-29 |
IL108149A (en) | 2005-05-17 |
KR100193107B1 (ko) | 1999-06-15 |
EP0675956A1 (en) | 1995-10-11 |
DE69332861T2 (de) | 2004-01-29 |
FI953091A0 (fi) | 1995-06-21 |
EP0675956B1 (en) | 2003-04-09 |
WO1994014959A1 (en) | 1994-07-07 |
ITRM920919A1 (it) | 1994-06-22 |
FI953091A (fi) | 1995-06-21 |
CA2151156A1 (en) | 1994-07-07 |
AU5833594A (en) | 1994-07-19 |
FI116059B (fi) | 2005-09-15 |
NO952494L (no) | 1995-08-21 |
ES2193152T3 (es) | 2003-11-01 |
KR950704486A (ko) | 1995-11-20 |
AU690093B2 (en) | 1998-04-23 |
PT675956E (pt) | 2003-07-31 |
DK0675956T3 (da) | 2003-07-07 |
NO315800B1 (no) | 2003-10-27 |
IT1257184B (it) | 1996-01-10 |
NO952494D0 (no) | 1995-06-21 |
RU2177480C2 (ru) | 2001-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19961217 |