ITRM20040242A1 - "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine. - Google Patents

"7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.

Info

Publication number
ITRM20040242A1
ITRM20040242A1 IT000242A ITRM20040242A ITRM20040242A1 IT RM20040242 A1 ITRM20040242 A1 IT RM20040242A1 IT 000242 A IT000242 A IT 000242A IT RM20040242 A ITRM20040242 A IT RM20040242A IT RM20040242 A1 ITRM20040242 A1 IT RM20040242A1
Authority
IT
Italy
Prior art keywords
butossiimminometilcamptotecina
conjuged
integrine
antagonists
integrine antagonists
Prior art date
Application number
IT000242A
Other languages
English (en)
Italian (it)
Inventor
Domenico Alloatti
Pozzo Alma Dal
Sabrina Dallavalle
Giuseppe Giannini
Lucio Merlini
Ming Hong Ni
Sergio Penco
Claudio Pisano
Maria Ornella Tinti
Loredana Vesci
Franco Zunino
Original Assignee
Ist Naz Stud Cura Dei Tumori
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Naz Stud Cura Dei Tumori, Sigma Tau Ind Farmaceuti filed Critical Ist Naz Stud Cura Dei Tumori
Priority to IT000242A priority Critical patent/ITRM20040242A1/it
Publication of ITRM20040242A1 publication Critical patent/ITRM20040242A1/it
Priority to PCT/IT2005/000245 priority patent/WO2005110486A2/en
Priority to EP05743414A priority patent/EP1747020A2/en
Priority to CNA2005800152130A priority patent/CN101065150A/zh
Priority to BRPI0511077-7A priority patent/BRPI0511077A/pt
Priority to JP2007512729A priority patent/JP2007537243A/ja
Priority to CA002562569A priority patent/CA2562569A1/en
Priority to MXPA06012885A priority patent/MXPA06012885A/es
Priority to AU2005243883A priority patent/AU2005243883A1/en
Priority to US11/596,016 priority patent/US7589099B2/en
Priority to TW094114400A priority patent/TW200538123A/zh
Priority to ARP050101934A priority patent/AR049337A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT000242A 2004-05-13 2004-05-13 "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine. ITRM20040242A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT000242A ITRM20040242A1 (it) 2004-05-13 2004-05-13 "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.
US11/596,016 US7589099B2 (en) 2004-05-13 2005-04-28 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
BRPI0511077-7A BRPI0511077A (pt) 2004-05-13 2005-04-28 7-t-butoximinometilcamptotecina conjugada na posição 20 com antagonistas de integrina
EP05743414A EP1747020A2 (en) 2004-05-13 2005-04-28 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
CNA2005800152130A CN101065150A (zh) 2004-05-13 2005-04-28 在20位与整联蛋白拮抗剂缀合的7－叔丁氧基亚氨基甲基喜树碱
PCT/IT2005/000245 WO2005110486A2 (en) 2004-05-13 2005-04-28 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
JP2007512729A JP2007537243A (ja) 2004-05-13 2005-04-28 ２０位にてインテグリンアンタゴニストと接合した７−ｔ−ブトキシイミノメチルカンプトテシン
CA002562569A CA2562569A1 (en) 2004-05-13 2005-04-28 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
MXPA06012885A MXPA06012885A (es) 2004-05-13 2005-04-28 7-t-butoximinometilcamptotecina conjugada en posicion 20 con antagonistas de integrina.
AU2005243883A AU2005243883A1 (en) 2004-05-13 2005-04-28 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
TW094114400A TW200538123A (en) 2004-05-13 2005-05-04 7-t-butoxyiminomethylcamptothecin conjugated in position 20 with integrin antagonists
ARP050101934A AR049337A1 (es) 2004-05-13 2005-05-12 7-t-butoxiiminometilcamptotecina conjugada en la posicion 20 con antagonistas de la integrina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000242A ITRM20040242A1 (it) 2004-05-13 2004-05-13 "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.

Publications (1)

Publication Number Publication Date
ITRM20040242A1 true ITRM20040242A1 (it) 2004-08-13

Family

ID=35124315

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000242A ITRM20040242A1 (it) 2004-05-13 2004-05-13 "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine.

Country Status (12)

Country Link
US (1) US7589099B2 (cg-RX-API-DMAC7.html)
EP (1) EP1747020A2 (cg-RX-API-DMAC7.html)
JP (1) JP2007537243A (cg-RX-API-DMAC7.html)
CN (1) CN101065150A (cg-RX-API-DMAC7.html)
AR (1) AR049337A1 (cg-RX-API-DMAC7.html)
AU (1) AU2005243883A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0511077A (cg-RX-API-DMAC7.html)
CA (1) CA2562569A1 (cg-RX-API-DMAC7.html)
IT (1) ITRM20040242A1 (cg-RX-API-DMAC7.html)
MX (1) MXPA06012885A (cg-RX-API-DMAC7.html)
TW (1) TW200538123A (cg-RX-API-DMAC7.html)
WO (1) WO2005110486A2 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040239A1 (it) * 2004-05-13 2004-08-13 Sigma Tau Ind Farmaceuti Derivati ciclopeptidici ad attivita' antintegrine.
WO2011086553A1 (en) * 2010-01-13 2011-07-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Cyclic peptides, compositions comprising them and uses thereof as nucleases of nucleotidic macromolecules
CN103275094B (zh) * 2013-05-08 2015-07-08 中国农业科学院植物保护研究所 (20s)-喜树碱的衍生物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19815812A1 (de) * 1998-04-08 1999-10-14 Bayer Ag Modifizierte Cytostatika
ES2175919T3 (es) * 1999-03-09 2002-11-16 Sigma Tau Ind Farmaceuti Derivados del camptothecin con actividad antitumoral.
ITRM20020306A1 (it) * 2002-05-31 2003-12-01 Sigma Tau Ind Farmaceuti Esteri in posizione 20 di camptotecine.

Also Published As

Publication number Publication date
TW200538123A (en) 2005-12-01
BRPI0511077A (pt) 2007-12-26
AU2005243883A1 (en) 2005-11-24
WO2005110486A3 (en) 2007-03-08
JP2007537243A (ja) 2007-12-20
CN101065150A (zh) 2007-10-31
EP1747020A2 (en) 2007-01-31
AR049337A1 (es) 2006-07-19
MXPA06012885A (es) 2007-08-14
US20070225311A1 (en) 2007-09-27
WO2005110486A2 (en) 2005-11-24
CA2562569A1 (en) 2005-11-24
US7589099B2 (en) 2009-09-15

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