ITPD20040245A1 - Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali - Google Patents

Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali

Info

Publication number
ITPD20040245A1
ITPD20040245A1 IT000245A ITPD20040245A ITPD20040245A1 IT PD20040245 A1 ITPD20040245 A1 IT PD20040245A1 IT 000245 A IT000245 A IT 000245A IT PD20040245 A ITPD20040245 A IT PD20040245A IT PD20040245 A1 ITPD20040245 A1 IT PD20040245A1
Authority
IT
Italy
Prior art keywords
gell
usable
sulfate
prevention
hyaluronic acid
Prior art date
Application number
IT000245A
Other languages
English (en)
Italian (it)
Inventor
Davide Bellini
Vittorio Crescenzi
Cristina Longinotti
Anna Taglienti
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Priority to IT000245A priority Critical patent/ITPD20040245A1/it
Publication of ITPD20040245A1 publication Critical patent/ITPD20040245A1/it
Priority to AU2005291474A priority patent/AU2005291474B2/en
Priority to US11/664,754 priority patent/US8563039B2/en
Priority to CN2005800340303A priority patent/CN101035575B/zh
Priority to JP2007535074A priority patent/JP5385532B2/ja
Priority to KR1020077007821A priority patent/KR20070107658A/ko
Priority to RU2007112777/15A priority patent/RU2383336C2/ru
Priority to PCT/EP2005/010645 priority patent/WO2006037592A1/en
Priority to CA2583149A priority patent/CA2583149C/en
Priority to EP05800102A priority patent/EP1796752B1/en
Priority to MX2007004158A priority patent/MX2007004158A/es
Priority to BRPI0516568-7A priority patent/BRPI0516568A/pt
Priority to US13/468,405 priority patent/US8728524B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
IT000245A 2004-10-08 2004-10-08 Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali ITPD20040245A1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT000245A ITPD20040245A1 (it) 2004-10-08 2004-10-08 Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali
BRPI0516568-7A BRPI0516568A (pt) 2004-10-08 2005-10-03 biomateriais consistindo em ácido hialurÈnico sulfatado e gelana, bem como composição farmacêutica e uso dos mesmos
JP2007535074A JP5385532B2 (ja) 2004-10-08 2005-10-03 脊柱癒着の防止において使用される、硫酸化ヒアルロン酸とゲランとからなるバイオマテリアル
US11/664,754 US8563039B2 (en) 2004-10-08 2005-10-03 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
CN2005800340303A CN101035575B (zh) 2004-10-08 2005-10-03 用于防止脊髓粘连的由硫酸化透明质酸和吉兰糖胶组成的生物材料
AU2005291474A AU2005291474B2 (en) 2004-10-08 2005-10-03 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
KR1020077007821A KR20070107658A (ko) 2004-10-08 2005-10-03 척추 유착 예방에 이용되는 황산화 히알루론산 및 겔란으로구성된 생체 물질
RU2007112777/15A RU2383336C2 (ru) 2004-10-08 2005-10-03 Биоматериалы, состоящие из сульфатированной гиалуроновой кислоты и геллана, применяемые для предотвращения спаек в позвоночнике
PCT/EP2005/010645 WO2006037592A1 (en) 2004-10-08 2005-10-03 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
CA2583149A CA2583149C (en) 2004-10-08 2005-10-03 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
EP05800102A EP1796752B1 (en) 2004-10-08 2005-10-03 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
MX2007004158A MX2007004158A (es) 2004-10-08 2005-10-03 Biomateriales que consiste en el acido hialuronico sulfatado y gelano para utilizarse en la prevencion de adhesiones de la columna vertebral.
US13/468,405 US8728524B2 (en) 2004-10-08 2012-05-10 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000245A ITPD20040245A1 (it) 2004-10-08 2004-10-08 Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali

Publications (1)

Publication Number Publication Date
ITPD20040245A1 true ITPD20040245A1 (it) 2005-01-08

Family

ID=35610035

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000245A ITPD20040245A1 (it) 2004-10-08 2004-10-08 Biomateriali costituiti da acido ialuronico solfatato e gellano utilizzabili nella prevenzione delle adesioni spinali

Country Status (12)

Country Link
US (2) US8563039B2 (cg-RX-API-DMAC7.html)
EP (1) EP1796752B1 (cg-RX-API-DMAC7.html)
JP (1) JP5385532B2 (cg-RX-API-DMAC7.html)
KR (1) KR20070107658A (cg-RX-API-DMAC7.html)
CN (1) CN101035575B (cg-RX-API-DMAC7.html)
AU (1) AU2005291474B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0516568A (cg-RX-API-DMAC7.html)
CA (1) CA2583149C (cg-RX-API-DMAC7.html)
IT (1) ITPD20040245A1 (cg-RX-API-DMAC7.html)
MX (1) MX2007004158A (cg-RX-API-DMAC7.html)
RU (1) RU2383336C2 (cg-RX-API-DMAC7.html)
WO (1) WO2006037592A1 (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20050206A1 (it) * 2005-07-07 2007-01-08 Fidia Advanced Biopolymers Srl Biomateriali in forma di fibra da impiegarsi come dispositivi medici nel trattamento delle ferite e loro processi di produzione
JP5088864B2 (ja) * 2007-03-16 2012-12-05 オリンパス株式会社 生体組織補填材とその製造方法
US8343942B2 (en) 2008-04-04 2013-01-01 University Of Utah Research Foundation Methods for treating interstitial cystitis
JP5758797B2 (ja) * 2008-04-04 2015-08-05 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法
WO2009148985A2 (en) * 2008-06-03 2009-12-10 E. I. Du Pont De Nemours And Company A tissue coating for preventing undesired tissue-to-tissue adhesions
KR101406743B1 (ko) 2009-01-13 2014-06-20 페르가뭄 아베 상처, 흉터, 수술 후 유착 형성을 치료하기 위한 히알루론산 함유 조성물
IT1397247B1 (it) * 2009-05-14 2013-01-04 Fidia Farmaceutici Nuovi agenti regolatori dell'attivita' citochinica
CA2830933A1 (en) 2011-03-23 2012-09-27 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
ITMI20120664A1 (it) 2012-04-20 2013-10-21 Anika Therapeutics Srl Biomateriali a base di gellano per l'uso come filler in chirurgia
ITMI20130221A1 (it) * 2013-02-18 2014-08-19 Novagenit S R L Formulazione a base di polisaccaridi biocompatibili e biodegradabili da impiegare in chirurgia
WO2018053111A1 (en) 2016-09-15 2018-03-22 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
US10590257B2 (en) 2016-09-26 2020-03-17 The Board Of Trustees Of The Leland Stanford Junior University Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications
US11969526B2 (en) 2017-04-03 2024-04-30 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
US11975123B2 (en) 2018-04-02 2024-05-07 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
WO2020072495A1 (en) 2018-10-01 2020-04-09 The Board Of Trustees Of The Leland Stanford Junior University Injectable hydrogels for controlled release of immunomodulatory compounds
CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
RU2744752C1 (ru) * 2020-08-28 2021-03-15 Федеральное государственное бюджетное учреждение науки Институт проблем химико-энергетических технологий Сибирского отделения Российской академии наук (ИПХЭТ СО РАН) Способ получения противоспаечного материала

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4326053A (en) * 1978-12-04 1982-04-20 Merck & Co., Inc. Polysaccharide S-60 and bacterial fermentation process for its preparation
US5080893A (en) * 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
IT1254704B (it) * 1991-12-18 1995-10-09 Mini Ricerca Scient Tecnolog Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico
ITPD940054A1 (it) 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
RU2177332C2 (ru) * 1995-08-29 2001-12-27 Фидиа Адвансд Биополимерз, С.Р.Л. Биоматериал для предотвращения послеоперационных спаек, включающий производные гиалуроновой кислоты (варианты) и способ предотвращения послеоперационных спаек ткани
SE9603480L (sv) * 1996-09-23 1998-03-24 Johan Carlfors Beredningsform för svårlösliga läkemedel
AU738788B2 (en) 1997-04-04 2001-09-27 Fidia Farmaceutici S.P.A. N-sulphated hyaluronic acid compounds, derivatives thereof and a process for their preparation
IT1294797B1 (it) * 1997-07-28 1999-04-15 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante
GB0015682D0 (en) * 2000-06-28 2000-08-16 Bristol Myers Squibb Co Sprayable wound care composition
IT1317359B1 (it) * 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e
US20030219431A1 (en) * 2002-05-24 2003-11-27 Empire Pharmaceuticals, Inc. Treatment of neuronal and neurological damage associated with spinal cord injury

Also Published As

Publication number Publication date
US8563039B2 (en) 2013-10-22
RU2383336C2 (ru) 2010-03-10
US8728524B2 (en) 2014-05-20
AU2005291474B2 (en) 2011-06-02
JP2008515832A (ja) 2008-05-15
MX2007004158A (es) 2007-10-08
CN101035575B (zh) 2011-12-14
KR20070107658A (ko) 2007-11-07
US20090202639A1 (en) 2009-08-13
WO2006037592A1 (en) 2006-04-13
JP5385532B2 (ja) 2014-01-08
EP1796752B1 (en) 2012-12-12
CA2583149C (en) 2013-09-10
US20130184234A1 (en) 2013-07-18
AU2005291474A1 (en) 2006-04-13
RU2007112777A (ru) 2008-10-10
CA2583149A1 (en) 2006-04-13
EP1796752A1 (en) 2007-06-20
CN101035575A (zh) 2007-09-12
BRPI0516568A (pt) 2008-09-09

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