ITMI991731A0 - Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piper idine - Google Patents

Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piper idine

Info

Publication number
ITMI991731A0
ITMI991731A0 IT99MI001731A ITMI991731A ITMI991731A0 IT MI991731 A0 ITMI991731 A0 IT MI991731A0 IT 99MI001731 A IT99MI001731 A IT 99MI001731A IT MI991731 A ITMI991731 A IT MI991731A IT MI991731 A0 ITMI991731 A0 IT MI991731A0
Authority
IT
Italy
Prior art keywords
phenyl
preparation
substituted derivatives
piper idine
idine
Prior art date
Application number
IT99MI001731A
Other languages
English (en)
Inventor
Ferra Lorenzo De
Pietro Massardo
Giorgio Cignarella
Oreste Piccolo
Original Assignee
Chemi Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemi Spa filed Critical Chemi Spa
Publication of ITMI991731A0 publication Critical patent/ITMI991731A0/it
Priority to IT1999MI001731A priority Critical patent/IT1313702B1/it
Priority to US09/627,689 priority patent/US6444822B1/en
Priority to ES00116505T priority patent/ES2191587T3/es
Priority to DE60001296T priority patent/DE60001296T2/de
Priority to EP00116505A priority patent/EP1074550B1/en
Priority to AT00116505T priority patent/ATE231858T1/de
Priority to CA002314750A priority patent/CA2314750A1/en
Priority to JP2000234404A priority patent/JP2001081089A/ja
Publication of ITMI991731A1 publication Critical patent/ITMI991731A1/it
Application granted granted Critical
Publication of IT1313702B1 publication Critical patent/IT1313702B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT1999MI001731A 1999-08-02 1999-08-02 Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine. IT1313702B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1999MI001731A IT1313702B1 (it) 1999-08-02 1999-08-02 Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine.
US09/627,689 US6444822B1 (en) 1999-08-02 2000-07-28 Process for the preparation of 3-substituted 4-phenyl-piperidine derivative
EP00116505A EP1074550B1 (en) 1999-08-02 2000-07-31 Process for the preparation of 3-substituted 4-phenyl-piperidine derivatives
DE60001296T DE60001296T2 (de) 1999-08-02 2000-07-31 Verfahren zur Herstellung von 3-substituierten 4-Phenyl-Piperidin Derivaten
ES00116505T ES2191587T3 (es) 1999-08-02 2000-07-31 Procedimiento para la preparacion de derivados de 4-fenil-piperidina 3-sustituida.
AT00116505T ATE231858T1 (de) 1999-08-02 2000-07-31 Verfahren zur herstellung von 3-substituierten 4- phenyl-piperidin derivaten
CA002314750A CA2314750A1 (en) 1999-08-02 2000-08-01 Process for the preparation of 3-substituted 4-phenyl-piperidine derivatives
JP2000234404A JP2001081089A (ja) 1999-08-02 2000-08-02 ３−置換−４−フェニル−ピペリジン誘導体の製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001731A IT1313702B1 (it) 1999-08-02 1999-08-02 Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine.

Publications (3)

Publication Number Publication Date
ITMI991731A0 true ITMI991731A0 (it) 1999-08-02
ITMI991731A1 ITMI991731A1 (it) 2001-02-02
IT1313702B1 IT1313702B1 (it) 2002-09-09

Family

ID=11383481

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001731A IT1313702B1 (it) 1999-08-02 1999-08-02 Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine.

Country Status (8)

Country Link
US (1) US6444822B1 (it)
EP (1) EP1074550B1 (it)
JP (1) JP2001081089A (it)
AT (1) ATE231858T1 (it)
CA (1) CA2314750A1 (it)
DE (1) DE60001296T2 (it)
ES (1) ES2191587T3 (it)
IT (1) IT1313702B1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739561D1 (de) 1996-06-13 2009-10-15 Sumitomo Chemical Co Piperidin Derivative als Zwischenprodukte zur Herstellung von Paroxetine und Verfahren zu ihrer Herstellung
GB9930577D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Novel process
HUP0401895A2 (hu) 2001-10-22 2004-12-28 Synthon B.V. Paroxetin N-formil származékai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
CN102008978B (zh) * 2010-11-24 2012-10-03 郑州大学 手性催化剂及其制备方法和应用
WO2017037662A1 (en) * 2015-09-03 2017-03-09 Piramal Enterprises Limited An improved process for the preparation of paroxetine and its intermediate
WO2023102477A1 (en) * 2021-12-02 2023-06-08 The Johns Hopkins University Peripherally and luminally-restricted inhibitors of the serotonin transporter as treatments for disorders of gastrointestinal motility

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
EP0190496A3 (en) 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
DE3680184D1 (de) 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine
JPH11505229A (ja) 1995-05-17 1999-05-18 ノボ ノルディスク アクティーゼルスカブ ４−アリール−ピペリジン誘導体を製造する方法
NZ315677A (en) * 1995-09-07 2000-02-28 F 4-(oxyalkoxyphenyl)-3-oxy-piperidines for treating heart and kidney insufficiency
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
AP9901698A0 (en) * 1997-05-29 1999-12-31 Smithkline Beecham Corp Novel process.

Also Published As

Publication number Publication date
DE60001296D1 (de) 2003-03-06
US6444822B1 (en) 2002-09-03
ITMI991731A1 (it) 2001-02-02
EP1074550A1 (en) 2001-02-07
JP2001081089A (ja) 2001-03-27
EP1074550B1 (en) 2003-01-29
DE60001296T2 (de) 2003-12-11
IT1313702B1 (it) 2002-09-09
ATE231858T1 (de) 2003-02-15
CA2314750A1 (en) 2001-02-02
ES2191587T3 (es) 2003-09-16

Similar Documents

Publication Publication Date Title
EE200200095A (et) Sulfonüülkarboksamiidi derivaadid, nende kasutamine, ravim ja nende valmistamismeetod
AU7414300A (en) Method for the production of substituted pyrimidine derivatives
IT1317741B1 (it) Metodo per la preparazione di 5-cianoftalide.
NO20006039D0 (no) Fremgangsmåte for fremstilling av 4-karboksyamino-2- substituert-1,2,3,4- tetrahydroquinolin
ITMI991731A0 (it) Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piper idine
IT1319242B1 (it) Processo per la preparazione di maleato di fluvossamina.
IT1313592B1 (it) Derivati di 1h-pirido 3,4-b indol-1-one.
EE200200014A (et) Dibensotiasepiiniderivaatide valmistamismeetod
GB2363605B (en) Process for the preparation of alpha-aminoketone derivatives
NO20013995D0 (no) Fremgangsmate for fremstilling av L-sorbose
DK1202949T3 (da) Fremgangsmåde til fremstilling af acylerede 1,3-dicarbonylforbindelser
NO20011652D0 (no) Fremgangsmåte for fremstilling av 1,5-diaryl-3-substituerte pyrazoler
NO20020308D0 (no) Fremgangsmåte for fremstilling av epothiolon B og derivater, såvel som mellomprodukter for fremgangsmåten
NO20022956D0 (no) Fremgangsmåte for fremstilling av nitroguanidin
NO20012811D0 (no) Fremgangsmåte for fremstilling av p-klorfenyl-propanol- derivat
NO20013044L (no) Fremgangsmåte for fremstilling av NG-substituerte deaza- adenosinderivater
NO20020328D0 (no) Fremgangsmåte for fremstilling av 4-cyano-2-aminometyltiazol
FR2797443B1 (fr) Procede de prepartion de quinoleine-5,8-diones
ITMI991655A0 (it) Processo per la sintesi di derivati beta-lattamici
NO20020327D0 (no) Fremgangsmåte for fremstilling av 2-aminometyl-4-cyano-tiazol
FR2795731B1 (fr) PROCEDE DE PREPARATION DE [1,4] DIAZEPINO [6,7,1-hi] INDOL-4-ONES SUBSTITUEES
FR2817550B1 (fr) Procede de preparation de derives de pyrrolidine substituee
IT1312551B1 (it) Processo per la sintesi di 5-alchilbenzodiossoli
ITMI991730A0 (it) Processo per la preparazione di trans-4-p-fluorofenil-3-idrossimetil-p iperidina
ITMI992492A0 (it) Processo per la preparazione di (4-metiltio-fenil-acetonitrile