ITMI991452A0 - Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo[b,f! azepinica - Google Patents

Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo[b,f! azepinica

Info

Publication number
ITMI991452A0
ITMI991452A0 IT99MI001452A ITMI991452A ITMI991452A0 IT MI991452 A0 ITMI991452 A0 IT MI991452A0 IT 99MI001452 A IT99MI001452 A IT 99MI001452A IT MI991452 A ITMI991452 A IT MI991452A IT MI991452 A0 ITMI991452 A0 IT MI991452A0
Authority
IT
Italy
Prior art keywords
azepinic
dibenzo
receptors
selective antagonists
antagonists
Prior art date
Application number
IT99MI001452A
Other languages
English (en)
Inventor
Patrizia Maria Luisa Terni
Giacomina Roberta Mandelli
Stefano Maiorana
Bruno Pietro Imbimbo
Original Assignee
Mediolanum Farmaceutici Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Farmaceutici Srl filed Critical Mediolanum Farmaceutici Srl
Priority to IT1999MI001452A priority Critical patent/ITMI991452A1/it
Publication of ITMI991452A0 publication Critical patent/ITMI991452A0/it
Priority to PCT/EP2000/006020 priority patent/WO2001002386A1/en
Priority to AU59796/00A priority patent/AU5979600A/en
Publication of ITMI991452A1 publication Critical patent/ITMI991452A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT1999MI001452A 1999-07-01 1999-07-01 Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica ITMI991452A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT1999MI001452A ITMI991452A1 (it) 1999-07-01 1999-07-01 Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica
PCT/EP2000/006020 WO2001002386A1 (en) 1999-07-01 2000-06-28 SELECTIVE M2 MUSCARINIC RECEPTOR ANTAGONISTS HAVING 5H-DIBENZ[b,f]AZEPINE STRUCTURE
AU59796/00A AU5979600A (en) 1999-07-01 2000-06-28 Selective m2 muscarinic receptor antagonists having 5h-dibenz[b,f]azepine structure

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI001452A ITMI991452A1 (it) 1999-07-01 1999-07-01 Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica

Publications (2)

Publication Number Publication Date
ITMI991452A0 true ITMI991452A0 (it) 1999-07-01
ITMI991452A1 ITMI991452A1 (it) 2001-01-01

Family

ID=11383261

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999MI001452A ITMI991452A1 (it) 1999-07-01 1999-07-01 Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica

Country Status (3)

Country Link
AU (1) AU5979600A (it)
IT (1) ITMI991452A1 (it)
WO (1) WO2001002386A1 (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2007109794A (ru) 2004-08-19 2008-09-27 Вертекс Фармасьютикалз, Инкорпорейтед (Us) Модуляторы мускариновых рецепторов
US7786141B2 (en) 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
AU2005309365B2 (en) 2004-11-29 2011-10-06 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
AU2006330866A1 (en) 2005-12-22 2007-07-05 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
EP1988892A2 (en) 2006-02-22 2008-11-12 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
ATE517106T1 (de) 2006-02-22 2011-08-15 Vertex Pharma Kondensierte spiropiperidine als modulatoren muskarinartiger rezeptoren
CN101500565A (zh) 2006-06-29 2009-08-05 弗特克斯药品有限公司 毒蕈碱性受体的调节剂
CN101553231A (zh) 2006-08-15 2009-10-07 弗特克斯药品有限公司 毒蕈碱受体调节剂
JP2010501561A (ja) 2006-08-18 2010-01-21 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体の調節剤
PT2178858E (pt) * 2007-08-02 2012-02-24 Recordati Ireland Ltd Novos compostos heterocíclicos como antagonistas de mglu5
CA2700724A1 (en) 2007-10-03 2009-04-09 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
US20180360845A1 (en) * 2015-07-20 2018-12-20 Chase Pharmaceuticals Corporation Muscarinic combination of a selective m2-antagonist and a peripheral non-selective antagonist for treating hypocholinergic disorders
CN115448871B (zh) * 2022-08-30 2023-07-11 中国药科大学 一种盐酸替罗非班的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3638950B2 (ja) * 1993-04-05 2005-04-13 マンカインド コーポレイション 神経障害の治療用ｍ▲下２▼レセプターリガンド
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands

Also Published As

Publication number Publication date
AU5979600A (en) 2001-01-22
ITMI991452A1 (it) 2001-01-01
WO2001002386A1 (en) 2001-01-11

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