ITMI921554A1 - Procedimento per la preparazione degli enantiomeri della dropropizina - Google Patents

Procedimento per la preparazione degli enantiomeri della dropropizina

Info

Publication number
ITMI921554A1
ITMI921554A1 IT001554A ITMI921554A ITMI921554A1 IT MI921554 A1 ITMI921554 A1 IT MI921554A1 IT 001554 A IT001554 A IT 001554A IT MI921554 A ITMI921554 A IT MI921554A IT MI921554 A1 ITMI921554 A1 IT MI921554A1
Authority
IT
Italy
Prior art keywords
dropropizine
preparation
enantiomers
procedure
propanediol
Prior art date
Application number
IT001554A
Other languages
English (en)
Inventor
Carlo Bombarda
Gianbattista Paradisi
Carlo Polacci
Original Assignee
Bidachem Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bidachem Spa filed Critical Bidachem Spa
Priority to ITMI921554A priority Critical patent/IT1254993B/it
Publication of ITMI921554A0 publication Critical patent/ITMI921554A0/it
Priority to EP93108659A priority patent/EP0575776B1/en
Priority to DE69324193T priority patent/DE69324193T2/de
Priority to ES93108659T priority patent/ES2130190T3/es
Priority to DK93108659T priority patent/DK0575776T3/da
Priority to AT93108659T priority patent/ATE178324T1/de
Publication of ITMI921554A1 publication Critical patent/ITMI921554A1/it
Application granted granted Critical
Publication of IT1254993B publication Critical patent/IT1254993B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ITMI921554A 1992-06-24 1992-06-24 Procedimento per la preparazione degli enantiomeri della dropropizina IT1254993B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITMI921554A IT1254993B (it) 1992-06-24 1992-06-24 Procedimento per la preparazione degli enantiomeri della dropropizina
EP93108659A EP0575776B1 (en) 1992-06-24 1993-05-28 A process for the preparation of enantiomers of dropropizine
DE69324193T DE69324193T2 (de) 1992-06-24 1993-05-28 Verfahren zur Herstellung von Enantiomeren von Dropropizin
ES93108659T ES2130190T3 (es) 1992-06-24 1993-05-28 Procedimiento para la preparacion de enantiomeros de dropropizina.
DK93108659T DK0575776T3 (da) 1992-06-24 1993-05-28 Fremgangsmåde til fremstilling af enantiomerer af dropropizin
AT93108659T ATE178324T1 (de) 1992-06-24 1993-05-28 Verfahren zur herstellung von enantiomeren von dropropizin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921554A IT1254993B (it) 1992-06-24 1992-06-24 Procedimento per la preparazione degli enantiomeri della dropropizina

Publications (3)

Publication Number Publication Date
ITMI921554A0 ITMI921554A0 (it) 1992-06-24
ITMI921554A1 true ITMI921554A1 (it) 1993-12-24
IT1254993B IT1254993B (it) 1995-10-11

Family

ID=11363573

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921554A IT1254993B (it) 1992-06-24 1992-06-24 Procedimento per la preparazione degli enantiomeri della dropropizina

Country Status (6)

Country Link
EP (1) EP0575776B1 (it)
AT (1) ATE178324T1 (it)
DE (1) DE69324193T2 (it)
DK (1) DK0575776T3 (it)
ES (1) ES2130190T3 (it)
IT (1) IT1254993B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4405387A1 (de) * 1994-02-19 1995-08-24 Hoechst Ag Verfahren zur Herstellung von Polyalkyl-1-oxa-diazaspirodecan-Verbindungen
IT1318650B1 (it) * 2000-07-28 2003-08-27 Dompe Spa 1,3-diossolani ad attivita' antitosse.
CN105481795B (zh) * 2015-12-31 2018-01-26 山东诚汇双达药业有限公司 一种左羟丙哌嗪的生产工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.

Also Published As

Publication number Publication date
DK0575776T3 (da) 1999-10-18
DE69324193T2 (de) 1999-07-15
EP0575776A3 (it) 1994-04-13
ATE178324T1 (de) 1999-04-15
EP0575776A2 (en) 1993-12-29
IT1254993B (it) 1995-10-11
ES2130190T3 (es) 1999-07-01
ITMI921554A0 (it) 1992-06-24
EP0575776B1 (en) 1999-03-31
DE69324193D1 (de) 1999-05-06

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970626