DE69324193D1 - Verfahren zur Herstellung von Enantiomeren von Dropropizin - Google Patents
Verfahren zur Herstellung von Enantiomeren von DropropizinInfo
- Publication number
- DE69324193D1 DE69324193D1 DE69324193T DE69324193T DE69324193D1 DE 69324193 D1 DE69324193 D1 DE 69324193D1 DE 69324193 T DE69324193 T DE 69324193T DE 69324193 T DE69324193 T DE 69324193T DE 69324193 D1 DE69324193 D1 DE 69324193D1
- Authority
- DE
- Germany
- Prior art keywords
- dropropizine
- preparation
- enantiomers
- propanediol
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI921554A IT1254993B (it) | 1992-06-24 | 1992-06-24 | Procedimento per la preparazione degli enantiomeri della dropropizina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69324193D1 true DE69324193D1 (de) | 1999-05-06 |
| DE69324193T2 DE69324193T2 (de) | 1999-07-15 |
Family
ID=11363573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69324193T Expired - Lifetime DE69324193T2 (de) | 1992-06-24 | 1993-05-28 | Verfahren zur Herstellung von Enantiomeren von Dropropizin |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0575776B1 (de) |
| AT (1) | ATE178324T1 (de) |
| DE (1) | DE69324193T2 (de) |
| DK (1) | DK0575776T3 (de) |
| ES (1) | ES2130190T3 (de) |
| IT (1) | IT1254993B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4405387A1 (de) * | 1994-02-19 | 1995-08-24 | Hoechst Ag | Verfahren zur Herstellung von Polyalkyl-1-oxa-diazaspirodecan-Verbindungen |
| IT1318650B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | 1,3-diossolani ad attivita' antitosse. |
| CN105481795B (zh) * | 2015-12-31 | 2018-01-26 | 山东诚汇双达药业有限公司 | 一种左羟丙哌嗪的生产工艺 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
| NL8801622A (nl) * | 1988-06-25 | 1990-01-16 | Stamicarbon | Bereiding van enantiomeren van dropropizine. |
| IT1226570B (it) * | 1988-08-01 | 1991-01-24 | Bidachem Spa | Procedimento di preparazione della levo- e destro-dropropizina |
| IT1231158B (it) * | 1989-07-20 | 1991-11-19 | Dompe Farmaceutici Spa | Procedimento per la risoluzione ottica della dropropizina. |
-
1992
- 1992-06-24 IT ITMI921554A patent/IT1254993B/it active IP Right Grant
-
1993
- 1993-05-28 DE DE69324193T patent/DE69324193T2/de not_active Expired - Lifetime
- 1993-05-28 DK DK93108659T patent/DK0575776T3/da active
- 1993-05-28 EP EP93108659A patent/EP0575776B1/de not_active Expired - Lifetime
- 1993-05-28 AT AT93108659T patent/ATE178324T1/de active
- 1993-05-28 ES ES93108659T patent/ES2130190T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2130190T3 (es) | 1999-07-01 |
| DK0575776T3 (da) | 1999-10-18 |
| ATE178324T1 (de) | 1999-04-15 |
| EP0575776A3 (de) | 1994-04-13 |
| EP0575776A2 (de) | 1993-12-29 |
| ITMI921554A0 (it) | 1992-06-24 |
| ITMI921554A1 (it) | 1993-12-24 |
| EP0575776B1 (de) | 1999-03-31 |
| DE69324193T2 (de) | 1999-07-15 |
| IT1254993B (it) | 1995-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |