ITMI20051743A1 - Uso di coniugati della doxorubicina con albumina lattosaminata - Google Patents

Uso di coniugati della doxorubicina con albumina lattosaminata

Info

Publication number
ITMI20051743A1
ITMI20051743A1 IT001743A ITMI20051743A ITMI20051743A1 IT MI20051743 A1 ITMI20051743 A1 IT MI20051743A1 IT 001743 A IT001743 A IT 001743A IT MI20051743 A ITMI20051743 A IT MI20051743A IT MI20051743 A1 ITMI20051743 A1 IT MI20051743A1
Authority
IT
Italy
Prior art keywords
hccs
treatment
conjugate
receptor
albumin
Prior art date
Application number
IT001743A
Other languages
English (en)
Inventor
Stefano Giuseppina Di
Luigi Fiume
Original Assignee
Uni Di Bologna Dipartimento Di Patologia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni Di Bologna Dipartimento Di Patologia Spa filed Critical Uni Di Bologna Dipartimento Di Patologia Spa
Priority to IT001743A priority Critical patent/ITMI20051743A1/it
Priority to CNA2006800343753A priority patent/CN101267842A/zh
Priority to US12/067,211 priority patent/US20080227710A1/en
Priority to DE602006018499T priority patent/DE602006018499D1/de
Priority to AT06793626T priority patent/ATE489139T1/de
Priority to EP06793626A priority patent/EP1937310B8/en
Priority to ES06793626T priority patent/ES2357031T3/es
Priority to PCT/EP2006/066489 priority patent/WO2007039448A2/en
Publication of ITMI20051743A1 publication Critical patent/ITMI20051743A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT001743A 2005-09-20 2005-09-20 Uso di coniugati della doxorubicina con albumina lattosaminata ITMI20051743A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT001743A ITMI20051743A1 (it) 2005-09-20 2005-09-20 Uso di coniugati della doxorubicina con albumina lattosaminata
CNA2006800343753A CN101267842A (zh) 2005-09-20 2006-09-19 阿霉素与乳糖胺化白蛋白的轭合物的用途
US12/067,211 US20080227710A1 (en) 2005-09-20 2006-09-19 Use of Conjugates of Doxorubicin with Lactosaminated Albumin
DE602006018499T DE602006018499D1 (de) 2005-09-20 2006-09-19 Verwendung von konjugaten von doxorubicin mit lactosaminiertem albumin
AT06793626T ATE489139T1 (de) 2005-09-20 2006-09-19 Verwendung von konjugaten von doxorubicin mit lactosaminiertem albumin
EP06793626A EP1937310B8 (en) 2005-09-20 2006-09-19 Use of conjugates of doxorubicin with lactosaminated albumin
ES06793626T ES2357031T3 (es) 2005-09-20 2006-09-19 Uso de conjugados de doxorrubicina con albúmina lactosaminada.
PCT/EP2006/066489 WO2007039448A2 (en) 2005-09-20 2006-09-19 Use of conjugates of doxorubicin with lactosaminated albumin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001743A ITMI20051743A1 (it) 2005-09-20 2005-09-20 Uso di coniugati della doxorubicina con albumina lattosaminata

Publications (1)

Publication Number Publication Date
ITMI20051743A1 true ITMI20051743A1 (it) 2007-03-21

Family

ID=37665721

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001743A ITMI20051743A1 (it) 2005-09-20 2005-09-20 Uso di coniugati della doxorubicina con albumina lattosaminata

Country Status (8)

Country Link
US (1) US20080227710A1 (it)
EP (1) EP1937310B8 (it)
CN (1) CN101267842A (it)
AT (1) ATE489139T1 (it)
DE (1) DE602006018499D1 (it)
ES (1) ES2357031T3 (it)
IT (1) ITMI20051743A1 (it)
WO (1) WO2007039448A2 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20040928A1 (it) 2004-05-07 2004-08-07 Uni Di Bologna Dipartiment O D Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
CN103656659B (zh) * 2012-09-26 2016-01-06 包骏 一种靶向载体、抗肿瘤药物及其应用
CN106344930B (zh) * 2015-07-16 2021-08-17 亚飞（上海）生物医药科技有限公司 分子定点靶向和激活的短肽阿霉素的制备和用途
RU2696096C2 (ru) * 2017-12-07 2019-07-31 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Низкомолекулярные конъюгаты противоопухолевых агентов и высокоселективных лигандов асиалогликопротеинового рецептора для терапии онкологических патологий печени
CN108671238A (zh) * 2018-05-14 2018-10-19 江苏医药职业学院 一种联合治疗高肿瘤渗透性白蛋白纳米系统的制备方法
CN109157662B (zh) * 2018-06-06 2021-07-20 北京大学 一种人血清白蛋白-阿霉素交联物纳米颗粒及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025239A1 (en) * 1992-06-17 1993-12-23 Advanced Magnetics Inc. Arabinogalactan derivatives and uses thereof
ITMI20040928A1 (it) * 2004-05-07 2004-08-07 Uni Di Bologna Dipartiment O D Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
US8147805B2 (en) * 2005-01-05 2012-04-03 The Board of Regents of The University of T exas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications

Also Published As

Publication number Publication date
EP1937310A2 (en) 2008-07-02
US20080227710A1 (en) 2008-09-18
WO2007039448A3 (en) 2007-05-31
ATE489139T1 (de) 2010-12-15
WO2007039448A2 (en) 2007-04-12
ES2357031T3 (es) 2011-04-15
EP1937310B1 (en) 2010-11-24
EP1937310B8 (en) 2011-07-13
DE602006018499D1 (de) 2011-01-05
CN101267842A (zh) 2008-09-17

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