ATE489139T1 - Verwendung von konjugaten von doxorubicin mit lactosaminiertem albumin - Google Patents
Verwendung von konjugaten von doxorubicin mit lactosaminiertem albuminInfo
- Publication number
- ATE489139T1 ATE489139T1 AT06793626T AT06793626T ATE489139T1 AT E489139 T1 ATE489139 T1 AT E489139T1 AT 06793626 T AT06793626 T AT 06793626T AT 06793626 T AT06793626 T AT 06793626T AT E489139 T1 ATE489139 T1 AT E489139T1
- Authority
- AT
- Austria
- Prior art keywords
- hccs
- treatment
- conjugate
- doxorubicin
- receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001743A ITMI20051743A1 (it) | 2005-09-20 | 2005-09-20 | Uso di coniugati della doxorubicina con albumina lattosaminata |
| PCT/EP2006/066489 WO2007039448A2 (en) | 2005-09-20 | 2006-09-19 | Use of conjugates of doxorubicin with lactosaminated albumin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489139T1 true ATE489139T1 (de) | 2010-12-15 |
Family
ID=37665721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06793626T ATE489139T1 (de) | 2005-09-20 | 2006-09-19 | Verwendung von konjugaten von doxorubicin mit lactosaminiertem albumin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080227710A1 (de) |
| EP (1) | EP1937310B8 (de) |
| CN (1) | CN101267842A (de) |
| AT (1) | ATE489139T1 (de) |
| DE (1) | DE602006018499D1 (de) |
| ES (1) | ES2357031T3 (de) |
| IT (1) | ITMI20051743A1 (de) |
| WO (1) | WO2007039448A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20040928A1 (it) | 2004-05-07 | 2004-08-07 | Uni Di Bologna Dipartiment O D | Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata |
| CN103656659B (zh) * | 2012-09-26 | 2016-01-06 | 包骏 | 一种靶向载体、抗肿瘤药物及其应用 |
| CN106344930B (zh) * | 2015-07-16 | 2021-08-17 | 亚飞（上海）生物医药科技有限公司 | 分子定点靶向和激活的短肽阿霉素的制备和用途 |
| RU2696096C2 (ru) * | 2017-12-07 | 2019-07-31 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Низкомолекулярные конъюгаты противоопухолевых агентов и высокоселективных лигандов асиалогликопротеинового рецептора для терапии онкологических патологий печени |
| CN108671238A (zh) * | 2018-05-14 | 2018-10-19 | 江苏医药职业学院 | 一种联合治疗高肿瘤渗透性白蛋白纳米系统的制备方法 |
| CN109157662B (zh) * | 2018-06-06 | 2021-07-20 | 北京大学 | 一种人血清白蛋白-阿霉素交联物纳米颗粒及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993025239A1 (en) * | 1992-06-17 | 1993-12-23 | Advanced Magnetics Inc. | Arabinogalactan derivatives and uses thereof |
| ITMI20040928A1 (it) * | 2004-05-07 | 2004-08-07 | Uni Di Bologna Dipartiment O D | Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata |
| EP1846042A2 (de) * | 2005-01-05 | 2007-10-24 | Board of Regents, The University of Texas System | Konjugate zur doppelten abbildung und radiochemotherapie: zusammensetzung sowie herstellung und anwendungen davon |
-
2005
- 2005-09-20 IT IT001743A patent/ITMI20051743A1/it unknown
-
2006
- 2006-09-19 WO PCT/EP2006/066489 patent/WO2007039448A2/en active Application Filing
- 2006-09-19 ES ES06793626T patent/ES2357031T3/es active Active
- 2006-09-19 EP EP06793626A patent/EP1937310B8/de not_active Not-in-force
- 2006-09-19 AT AT06793626T patent/ATE489139T1/de not_active IP Right Cessation
- 2006-09-19 US US12/067,211 patent/US20080227710A1/en not_active Abandoned
- 2006-09-19 DE DE602006018499T patent/DE602006018499D1/de active Active
- 2006-09-19 CN CNA2006800343753A patent/CN101267842A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20051743A1 (it) | 2007-03-21 |
| WO2007039448A3 (en) | 2007-05-31 |
| WO2007039448A2 (en) | 2007-04-12 |
| US20080227710A1 (en) | 2008-09-18 |
| EP1937310B8 (de) | 2011-07-13 |
| DE602006018499D1 (de) | 2011-01-05 |
| EP1937310A2 (de) | 2008-07-02 |
| EP1937310B1 (de) | 2010-11-24 |
| ES2357031T3 (es) | 2011-04-15 |
| CN101267842A (zh) | 2008-09-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |