ITGE950132A1 - Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. - Google Patents
Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. Download PDFInfo
- Publication number
- ITGE950132A1 ITGE950132A1 IT95GE000132A ITGE950132A ITGE950132A1 IT GE950132 A1 ITGE950132 A1 IT GE950132A1 IT 95GE000132 A IT95GE000132 A IT 95GE000132A IT GE950132 A ITGE950132 A IT GE950132A IT GE950132 A1 ITGE950132 A1 IT GE950132A1
- Authority
- IT
- Italy
- Prior art keywords
- ion
- hypocal
- hypochlorous
- compound
- vital
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims description 4
- 238000004659 sterilization and disinfection Methods 0.000 title description 3
- 210000000170 cell membrane Anatomy 0.000 claims abstract description 3
- 239000000314 lubricant Substances 0.000 claims abstract description 3
- 239000011368 organic material Substances 0.000 claims abstract description 3
- 150000002500 ions Chemical class 0.000 claims description 7
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 5
- 229910001424 calcium ion Inorganic materials 0.000 claims description 5
- 239000000645 desinfectant Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 210000004053 periapical tissue Anatomy 0.000 claims description 4
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims description 3
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 3
- 229910001414 potassium ion Inorganic materials 0.000 claims description 3
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- 210000000988 bone and bone Anatomy 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 230000002188 osteogenic effect Effects 0.000 claims description 2
- 230000017423 tissue regeneration Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- 208000004550 Postoperative Pain Diseases 0.000 claims 2
- 230000001506 immunosuppresive effect Effects 0.000 claims 2
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 1
- 206010062016 Immunosuppression Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 210000004268 dentin Anatomy 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 231100001231 less toxic Toxicity 0.000 claims 1
- 230000007246 mechanism Effects 0.000 claims 1
- 230000007830 nerve conduction Effects 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 230000000704 physical effect Effects 0.000 claims 1
- 239000002630 root canal dressing Substances 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000002087 whitening effect Effects 0.000 abstract description 3
- 102000004190 Enzymes Human genes 0.000 abstract description 2
- 108090000790 Enzymes Proteins 0.000 abstract description 2
- 230000001120 cytoprotective effect Effects 0.000 abstract description 2
- 229960003444 immunosuppressant agent Drugs 0.000 abstract description 2
- 230000001861 immunosuppressant effect Effects 0.000 abstract description 2
- 239000003018 immunosuppressive agent Substances 0.000 abstract description 2
- 239000003381 stabilizer Substances 0.000 abstract description 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000010478 bone regeneration Effects 0.000 abstract 1
- 239000004744 fabric Substances 0.000 abstract 1
- 230000002262 irrigation Effects 0.000 description 2
- 238000003973 irrigation Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001338 necrotic effect Effects 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 210000004262 dental pulp cavity Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000000684 root canal irrigant Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/50—Preparations specially adapted for dental root treatment
- A61K6/52—Cleaning; Disinfecting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
IL PRODOTTO PRESENTA LE SEGUENTI PROPRIETA':DISINFESTANTE; LUBRIFICANTE; SBIANCANTE; DISSOLVENTE DEL MATERIALE ORGANICO; CITOPROTETTIVO; STABILIZZANTE DELLE MEMBRANE CELLULARI; ATTIVANTE DEGLI ENZIMI PER LA RIGENERAZIONE OSSEA E DEL TESSUTO PERIMETRALE; IMMUNOSOPPRESSORE; RIDUTTORE DEGLIALGOSTIMOLI.TUTTO CIO' E' OTTENUTO DALLA SINERGIA DEGLI IONI PRESENTI NELLA SOLUZIONE, OPPORTUNATAMENTE DOSATI.
Description
INVENZIONE INDUSTRIALE DAL TITOLO:
COMPOSTO AD USO ODONTOSTOMATOLOGICO PER LA DETERSIONE E DISINFEZIONE DEI CANALI RADICOLARI E DELLA DENTINA VITALE.
RIASSUNTO
Il prodotto presenta le seguenti proprietà': disinfettante; lubrificante; sbiancante; dissolvente del materiale organico; citoprotettivo; stabilizzante debile membrane cellulari; attivante degli,enzimi per la rigenerazione ossea e del tessuto periapicale; immunosopressore; riduttore degli algostimoli. Tutto ciò' e' ottenuto dalla sinergia degli ioni nella soluzione, opportunamente dosati.
DESCRIZIONE
Il liquido qui presentato, denominato "HYPOCAL-K", puro o diluito con acqua, viene utilizzato in odontostomatol.og.ia per l'irrigazione, la detersione e la disinfezione spinta del sistema endoriontico. La tecnica di utilizzo e' assimilabile a quella di altri irriganti canalari già' presenti in commercio, quali i composti a base rii sali di ammonio quaternari o a base di ipoclorito di sodio. L'irrigazione secondo le tecniche consuete, si effettua mediante siringa con ago montato. Il liquido penetra all'interno del sistema canalare e vi defluisce asportando residui pulpari, fango dentinale, materich e infetto e necrotico.
Le proprietà' che distinguono l'HYPOCAL-K da tutti gli altri irriganti canalari presenti in commercio, sono:
1) Elevato potere disinfettante, sbiancante, lubrificante e di dissoluzione dei residui necrotici dovuto allo ione ipocloroso.
2) Bassa tossicità' nei riguardi dei tessuti periapicali, dovuta alla presenza di ione calcio bivalente.
3) Significativa riduzione del dolore piostoperatorio, dovuta alla presenza di ione calcio bivalente e di ione potassio.
4) Significativo incremento dell'attività' osteogenic:a e cicatrizzante dei tessuti periapicali, dovuto alla presenza dello ione calcio in soluzione.
Nel complesso, l'uso di HYPDCAL-K presenta caratteristiche superiori a quelle di tutti cjli altri irriganti canalari fino ad ora proposti dal mercato.
La peculiarità' esclusiva dell'HYPOCAL-K e' l 'associazione in soluzione delle seguenti tre specie ioniche:
calcio bivalente;; potassio e ione ipocloroso.,
Claims (1)
- RIVENDICAZIONI A) Il liquido HYPOCAL-K possiede molteplici proprietà' chimico-fisiche e biologiche, attribuibili vai suoi componenti, di notevole utilità' in campo endodontico. I tre principi attivi contenuti nell' HYPOCAL-K sono: lo ione ipocloroso, lo ione calcio bivalente e lo .ione potassio. B) Lo ione ipocloroso possiede i seguenti effetti: - disinfettante - sterilizzante lubrificante --sbiancante -- di dissoluzione di materiale organico C) Lo ione calcio bivalente, contenuto in soluzione, confo risce al composto in primo luogo una maggiore biocompatibillta' rispetto valle altre soluzioni a base di ipoclorito di sodio presenti in commercio; inoltre esplica effetti quali: citoprotezione-Stabilizzazione delle membrane cellulari. Attivazione di meccanismi implicati nella rigenerazione ossea e del tessuto periapicale (quali la fosfatasi alcalina). Immunosoppressione. D) Lo ione potassio esplica un effetto fondamentale sul potenziale di azione neuronaie e quindi sulla conduzione nervosa, col risultato di ottenere una signifieativa riduzione degli algostimoli postoperatori, cosi' comuni in campo endodontico. E) Il complesso degli ioni presenti in questa soluzione rivendica le proprietà' prima descritte, con la particolare caratteristica di risultare molto meno tossico per i tessuti vitali rispetto all'ipoclorito di sodio ed in grado di ridurre significativamente il dolore postoperatorio. F) La particolare modalità' di rilascio dello ione ipocloroso, unito all'effetto osteogenico ed immunosoppressore del calcio, consente rii attribuire all' HYPOCAL-K anche il ruolo di "medicazione canalare intermedia", non rivendicabile-da nessun altro liquido irrigante canalare esistente m commercio HYPOCAL-K in opportuna diluizione rivendica la proprietà' di disinfettante cavitario (dentina vitale) in odontostomatologia
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95GE000132A ITGE950132A1 (it) | 1995-11-29 | 1995-11-29 | Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. |
| DE69628665T DE69628665D1 (de) | 1995-11-29 | 1996-11-28 | Zusammensetzung für odontostomatologische verwendung zur reinigung und desinfektion von zahnwurzelkanälen und lebensfähiges dentin |
| AU77100/96A AU7710096A (en) | 1995-11-29 | 1996-11-28 | A composition for odontostomatological use in cleaning and disinfecting the root canals and viable dentine |
| AT96940133T ATE242602T1 (de) | 1995-11-29 | 1996-11-28 | Zusammensetzung für odontostomatologische verwendung zur reinigung und desinfektion von zahnwurzelkanälen und lebensfähiges dentin |
| EP96940133A EP0876101B1 (en) | 1995-11-29 | 1996-11-28 | A composition for odontostomatological use in cleaning and disinfecting the root canals and viable dentine |
| PCT/IT1996/000232 WO1997019597A1 (en) | 1995-11-29 | 1996-11-28 | A composition for odontostomatological use in cleaning and disinfecting the root canals and viable dentine |
| US09/077,349 US5976509A (en) | 1995-11-29 | 1996-11-28 | Composition for odontostomatological use in cleaning and disinfecting the root canals and viable dentine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95GE000132A ITGE950132A1 (it) | 1995-11-29 | 1995-11-29 | Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITGE950132A0 ITGE950132A0 (it) | 1995-11-29 |
| ITGE950132A1 true ITGE950132A1 (it) | 1997-05-29 |
Family
ID=11354820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95GE000132A ITGE950132A1 (it) | 1995-11-29 | 1995-11-29 | Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5976509A (it) |
| EP (1) | EP0876101B1 (it) |
| AT (1) | ATE242602T1 (it) |
| AU (1) | AU7710096A (it) |
| DE (1) | DE69628665D1 (it) |
| IT (1) | ITGE950132A1 (it) |
| WO (1) | WO1997019597A1 (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042943A4 (en) * | 1997-12-30 | 2002-05-02 | Radical Waters Ip Pty Ltd | IRRIGATION MEDIUM FOR ROOT CHANNELS |
| SE514784C2 (sv) * | 1998-08-17 | 2001-04-23 | Mediteam Dental Ab | Metod och preparat för rengöring av rotytor och omgivande vävnader hos tänder |
| SE513404C2 (sv) * | 1999-01-19 | 2000-09-11 | Mediteam Dentalutveckling I Go | Preparat för kemisk-mekanisk tandbehandling innehållande en klorförening som aktiv komponent |
| FR2906713A1 (fr) * | 2006-10-05 | 2008-04-11 | Jean Camps | Composition pharmaceutique utilisee pour le soin des canaux radiculaires. |
| CN114176086B (zh) * | 2020-09-15 | 2022-09-27 | 中国科学院生态环境研究中心 | 一种杀灭灾害生物沼蛤的微囊化饵料及其制备与使用方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1435498A (en) * | 1920-01-16 | 1922-11-14 | Ernest D Resnik | Dentifrice |
| US3932605A (en) * | 1972-06-12 | 1976-01-13 | Jaroslav Vit | Dental treatment |
| US3998945A (en) * | 1972-06-12 | 1976-12-21 | National Patent Development Corporation | Dental treatment |
| US4155975A (en) * | 1976-11-01 | 1979-05-22 | Riley Harvey W | Deodorant and method for deodorizing livestock manure |
| US4755354A (en) * | 1984-07-20 | 1988-07-05 | The Procter & Gamble Company | Bromide activated hypochlorite cleaning of soiled toilet bowls |
| US5281392A (en) * | 1986-03-10 | 1994-01-25 | Rubinstein Alan I | Method for disinfecting red blood cells, blood products, and corneas |
| US4772414A (en) * | 1986-07-24 | 1988-09-20 | Ppg Industries, Inc. | Bleaching composition |
| US4780216A (en) * | 1986-11-19 | 1988-10-25 | Olin Corporation | Calcium hypochlorite sanitizing compositions |
| US4918181A (en) * | 1988-03-02 | 1990-04-17 | Karcher Dennis J | Tertiaryaminoalkyl-hydroxyalkyl ethers of polygalactomannans |
| US5049385A (en) * | 1988-06-30 | 1991-09-17 | Ppg Industries, Inc. | Solid halogen-containing composition and method for producing same |
| US5106559A (en) * | 1988-06-30 | 1992-04-21 | Ppg Industries, Inc. | Solid halogen-containing composition and method for producing same |
| US5599571A (en) * | 1989-12-06 | 1997-02-04 | Estrada; Joe J. | Process for preserving leafy produce |
| EP0701400A1 (en) * | 1993-06-03 | 1996-03-20 | Amuchina, Inc. | Sodium hypochlorite based disinfectant and sterilizer for medical-surgical instruments |
| US5709992A (en) * | 1994-08-17 | 1998-01-20 | Rubinstein; Alan I. | Method for disinfecting red blood cells |
| US5817337A (en) * | 1995-10-06 | 1998-10-06 | Desenna; Richard A. | Disinfectant effervescent tablet formulation |
| US5753602A (en) * | 1995-12-18 | 1998-05-19 | The Block Drug Company | Chlorine cleanser tabletting process and product |
-
1995
- 1995-11-29 IT IT95GE000132A patent/ITGE950132A1/it not_active Application Discontinuation
-
1996
- 1996-11-28 EP EP96940133A patent/EP0876101B1/en not_active Expired - Lifetime
- 1996-11-28 AU AU77100/96A patent/AU7710096A/en not_active Abandoned
- 1996-11-28 WO PCT/IT1996/000232 patent/WO1997019597A1/en active IP Right Grant
- 1996-11-28 US US09/077,349 patent/US5976509A/en not_active Expired - Fee Related
- 1996-11-28 DE DE69628665T patent/DE69628665D1/de not_active Expired - Lifetime
- 1996-11-28 AT AT96940133T patent/ATE242602T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7710096A (en) | 1997-06-19 |
| EP0876101A1 (en) | 1998-11-11 |
| WO1997019597A1 (en) | 1997-06-05 |
| EP0876101B1 (en) | 2003-06-11 |
| ATE242602T1 (de) | 2003-06-15 |
| US5976509A (en) | 1999-11-02 |
| ITGE950132A0 (it) | 1995-11-29 |
| DE69628665D1 (de) | 2003-07-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Topbas et al. | Endodontic irrigation solutions: A review: Endodontic irrigation solutions | |
| Agrawal Vineet et al. | A contemporary overview of endodontic irrigants–A review | |
| DE60017196T2 (de) | Ein topisches nicht-zytotoxisches antimikrobielles hydrogel mit thixotropischen eigenschaften | |
| Mohammadi et al. | Antimicrobial efficacy of chlorhexidine as a root canal irrigant: a literature review | |
| Solovyeva et al. | Cleaning effectiveness of root canal irrigation with electrochemically activated anolyte and catholyte solutions: a pilot study | |
| KR20050039835A (ko) | 생리적으로 배런스된 이온화 산성 용액 및 상처 치료에사용하는 방법론 | |
| JP2003520820A5 (it) | ||
| JP2003520820A (ja) | 生理学的にバランスのとれた、イオン化された酸性の溶液および創傷治癒におけるその使用方法 | |
| Kaur et al. | Irrigating solutions in pediatric dentistry: Literature review and update | |
| WO2015082937A2 (en) | Composition and uses thereof | |
| ES2011232T3 (es) | Composiciones farmaceuticas de piroxicam en soluciones acuosas y procedimiento para su preparacion. | |
| Mohanty et al. | Antimicrobial efficacy of apple cider vinegar against Enterococcus faecalis and Candida albicans: An in vitro study | |
| ES2318019T3 (es) | Agente para el tratamiento de heridas. | |
| ITGE950132A1 (it) | Composto ad uso odontostomatologico per la detersione e disinfezione dei canali radicolari e della dentina vitale. | |
| Kaur | Role of irrigants in endodontics | |
| AU2019280025A1 (en) | Wound treatment composition | |
| CN103800210B (zh) | 一种含蛋白酶的牙科、口腔科制剂及其制备方法 | |
| Mohammadi | Effects of root canal irrigants on the planktonic form of Enterococcus faecalis: a review | |
| EP2068892A1 (en) | Wound healing compositions | |
| Napte et al. | Endodontic irrigants | |
| ES2907961T3 (es) | Producción electrolítica de soluciones de cloramina orgánica | |
| Kashyap et al. | Irrigating solutions in pediatric dentistry: a big deal in little teeth | |
| RU2481818C1 (ru) | Способ очистки и дезинфекции съемных зубных протезов | |
| Venghat et al. | Irrigants used in endodontics | |
| Yano et al. | A literature review on intracanal irrigants in endodontics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0002 | Rejected |