IT8921244A0 - Procedimento per la risoluzione ottica della dropropizina. - Google Patents

Procedimento per la risoluzione ottica della dropropizina.

Info

Publication number
IT8921244A0
IT8921244A0 IT8921244A IT2124489A IT8921244A0 IT 8921244 A0 IT8921244 A0 IT 8921244A0 IT 8921244 A IT8921244 A IT 8921244A IT 2124489 A IT2124489 A IT 2124489A IT 8921244 A0 IT8921244 A0 IT 8921244A0
Authority
IT
Italy
Prior art keywords
dropropizine
procedure
optical resolution
resolution
optical
Prior art date
Application number
IT8921244A
Other languages
English (en)
Other versions
IT1231158B (it
Inventor
Roberto Giani
Original Assignee
Dompe Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici Spa filed Critical Dompe Farmaceutici Spa
Publication of IT8921244A0 publication Critical patent/IT8921244A0/it
Priority to IT8921244A priority Critical patent/IT1231158B/it
Priority to PT92767A priority patent/PT92767B/pt
Priority to ES8904429A priority patent/ES2019010A6/es
Priority to CA002007385A priority patent/CA2007385C/en
Priority to KR1019900000286A priority patent/KR0146047B1/ko
Priority to AT90113123T priority patent/ATE116975T1/de
Priority to EP90113123A priority patent/EP0409044B1/en
Priority to DE199090113123T priority patent/DE409044T1/de
Priority to DE69015907T priority patent/DE69015907T2/de
Priority to US07/553,796 priority patent/US5087698A/en
Priority to JP2192817A priority patent/JP2977237B2/ja
Priority to GR91300062T priority patent/GR910300062T1/el
Application granted granted Critical
Publication of IT1231158B publication Critical patent/IT1231158B/it
Priority to GR950400200T priority patent/GR3014936T3/el
Priority to HK98105521A priority patent/HK1006309A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Optical Couplings Of Light Guides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Indole Compounds (AREA)
  • Glass Compositions (AREA)
  • Semiconductor Lasers (AREA)
IT8921244A 1989-07-20 1989-07-20 Procedimento per la risoluzione ottica della dropropizina. IT1231158B (it)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT8921244A IT1231158B (it) 1989-07-20 1989-07-20 Procedimento per la risoluzione ottica della dropropizina.
PT92767A PT92767B (pt) 1989-07-20 1989-12-29 Processo para a resolucao da forma racemica de 3-(4-fenil-1-piperazinil)-1,2- -propanodiol (dropropizina) nos seus isomeros opticos
ES8904429A ES2019010A6 (es) 1989-07-20 1989-12-29 Un procedimiento de resolucion optica de dropropizina racemica.
CA002007385A CA2007385C (en) 1989-07-20 1990-01-09 Process for the optical resolution of dropropizine
KR1019900000286A KR0146047B1 (ko) 1989-07-20 1990-01-11 드로프로피진의 광학적 분할방법
EP90113123A EP0409044B1 (en) 1989-07-20 1990-07-10 A process for the optical resolution of dropropizine
AT90113123T ATE116975T1 (de) 1989-07-20 1990-07-10 Verfahren zur optischen trennung von dropropizin.
DE199090113123T DE409044T1 (de) 1989-07-20 1990-07-10 Verfahren zur optischen trennung von dropropizin.
DE69015907T DE69015907T2 (de) 1989-07-20 1990-07-10 Verfahren zur optischen Trennung von Dropropizin.
US07/553,796 US5087698A (en) 1989-07-20 1990-07-19 Process for the optical resolution of dropopizine
JP2192817A JP2977237B2 (ja) 1989-07-20 1990-07-19 ドロプロピジンの光学分割法
GR91300062T GR910300062T1 (en) 1989-07-20 1991-11-15 A process for the optical resolution of dropropizine
GR950400200T GR3014936T3 (en) 1989-07-20 1995-02-01 A process for the optical resolution of dropropizine.
HK98105521A HK1006309A1 (en) 1989-07-20 1998-06-17 A process for the optical resolution of droproizine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8921244A IT1231158B (it) 1989-07-20 1989-07-20 Procedimento per la risoluzione ottica della dropropizina.

Publications (2)

Publication Number Publication Date
IT8921244A0 true IT8921244A0 (it) 1989-07-20
IT1231158B IT1231158B (it) 1991-11-19

Family

ID=11178946

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8921244A IT1231158B (it) 1989-07-20 1989-07-20 Procedimento per la risoluzione ottica della dropropizina.

Country Status (12)

Country Link
US (1) US5087698A (it)
EP (1) EP0409044B1 (it)
JP (1) JP2977237B2 (it)
KR (1) KR0146047B1 (it)
AT (1) ATE116975T1 (it)
CA (1) CA2007385C (it)
DE (2) DE69015907T2 (it)
ES (1) ES2019010A6 (it)
GR (2) GR910300062T1 (it)
HK (1) HK1006309A1 (it)
IT (1) IT1231158B (it)
PT (1) PT92767B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254452B (it) * 1992-02-14 1995-09-25 Dompe Farmaceutici Spa N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
IT1254993B (it) * 1992-06-24 1995-10-11 Procedimento per la preparazione degli enantiomeri della dropropizina
IN187238B (it) * 1995-06-30 2002-03-09 Astra Ab
DE19821039A1 (de) 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE601394A (it) *
NL275711A (it) * 1962-03-15
US4255426A (en) * 1979-07-09 1981-03-10 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines
US4312877A (en) * 1979-07-09 1982-01-26 Pfizer Inc. 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted piperidines, pharmaceutical compositions, thereof and use thereof
IT1210639B (it) * 1981-02-25 1989-09-14 Menarini Sas Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono
NL8801622A (nl) * 1988-06-25 1990-01-16 Stamicarbon Bereiding van enantiomeren van dropropizine.
IT1217950B (it) * 1988-06-28 1990-03-30 Dott Formenti Ind Chimica E Fa Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina

Also Published As

Publication number Publication date
KR0146047B1 (ko) 1998-08-17
ES2019010A6 (es) 1991-05-16
GR910300062T1 (en) 1991-11-15
ATE116975T1 (de) 1995-01-15
EP0409044B1 (en) 1995-01-11
PT92767B (pt) 1995-11-30
EP0409044A3 (en) 1991-05-29
EP0409044A2 (en) 1991-01-23
KR910002745A (ko) 1991-02-26
JP2977237B2 (ja) 1999-11-15
CA2007385C (en) 1997-12-30
DE409044T1 (de) 1991-07-25
IT1231158B (it) 1991-11-19
JPH0381270A (ja) 1991-04-05
HK1006309A1 (en) 1999-02-19
US5087698A (en) 1992-02-11
DE69015907D1 (de) 1995-02-23
GR3014936T3 (en) 1995-05-31
PT92767A (pt) 1991-03-20
CA2007385A1 (en) 1991-01-20
DE69015907T2 (de) 1995-05-24

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970729