IT8567298A0 - Procedimento per la preparazione di 14 idrossi n etossicarbonil norco deinone - Google Patents
Procedimento per la preparazione di 14 idrossi n etossicarbonil norco deinoneInfo
- Publication number
- IT8567298A0 IT8567298A0 IT8567298A IT6729885A IT8567298A0 IT 8567298 A0 IT8567298 A0 IT 8567298A0 IT 8567298 A IT8567298 A IT 8567298A IT 6729885 A IT6729885 A IT 6729885A IT 8567298 A0 IT8567298 A0 IT 8567298A0
- Authority
- IT
- Italy
- Prior art keywords
- ethoxicarbonil
- deinone
- norco
- hydroxy
- procedure
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 title 1
- 229940099678 norco Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
- Noodles (AREA)
- Thermistors And Varistors (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/593,752 US4639520A (en) | 1984-03-27 | 1984-03-27 | Preparation of 14-hydroxy-N-ethoxy-carbonyl-norcodeinone |
Publications (3)
Publication Number | Publication Date |
---|---|
IT8567298A0 true IT8567298A0 (it) | 1985-03-26 |
IT8567298A1 IT8567298A1 (it) | 1986-09-26 |
IT1184058B IT1184058B (it) | 1987-10-22 |
Family
ID=24376012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT67298/85A IT1184058B (it) | 1984-03-27 | 1985-03-26 | Procedimento per la preparazione di 14 idrossi n etossicarbonil norco deinone |
Country Status (9)
Country | Link |
---|---|
US (1) | US4639520A (it) |
EP (1) | EP0159823B1 (it) |
JP (1) | JPH0651702B2 (it) |
AT (1) | ATE45358T1 (it) |
DE (1) | DE3572172D1 (it) |
ES (2) | ES8607306A1 (it) |
FR (1) | FR2566777B1 (it) |
IT (1) | IT1184058B (it) |
NO (1) | NO161975C (it) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4795813A (en) * | 1981-08-17 | 1989-01-03 | The Florida Board Of Regents On Behalf Of The Florida State University | Synthesis of derivatives of codeine and other 3-O-alkylmorphines |
US5112975A (en) * | 1984-03-27 | 1992-05-12 | Mallinckrodt Specialty Chemicals Company | Preparation of noroxymorphone from morphine |
US5668285A (en) * | 1986-10-31 | 1997-09-16 | The United States Of America As Represented By The Department Of Health And Human Services | Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates |
ES2129395T3 (es) * | 1989-10-16 | 1999-06-16 | Us Health | Sintesis total de enantiomeros de nortebaina, normorfina, noroximorfona y sus derivados a traves de productos intermedios n-nor. |
TWI483944B (zh) | 2004-03-30 | 2015-05-11 | Euro Celtique Sa | 含有小於25ppm14-羥可待因酮之羥可酮鹽酸鹽組成物、醫藥劑型、延遲釋出口服劑型及醫藥上可以接受的包裝 |
JP2008546688A (ja) * | 2005-06-16 | 2008-12-25 | マリンクロッド・インコーポレイテッド | 1−ハロ−テバインまたは類似体を介する14−ヒドロキシルオピエート類への合成経路 |
JP2010522189A (ja) * | 2007-03-23 | 2010-07-01 | マリンクロッド・インコーポレイテッド | オリパビンからのオキシモルホンの改善された調製 |
US8309727B2 (en) * | 2007-04-16 | 2012-11-13 | Mallinckrodt Llc | Opiate reduction utilizing catalytic hydrogen transfer reaction |
ES2549904T3 (es) * | 2008-05-27 | 2015-11-03 | Mallinckrodt Llc | Procesos y compuestos para la preparación de normorfinanos |
TWI471289B (zh) | 2010-06-11 | 2015-02-01 | Rhodes Technologies | 使三級胺進行n-脫烷反應之方法 |
CA2936749C (en) | 2010-06-11 | 2019-07-09 | Joshua R. Giguere | Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof |
DE102012108266A1 (de) | 2012-09-05 | 2014-03-06 | Aesculap Ag | Chirurgisches, Drehmoment übertragendes Instrument einschließlich zugehöriges Werkzeug |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2772270A (en) * | 1954-10-21 | 1956-11-27 | M J Lewenstein | 14-hydroxymorphinone and 8, 14-dihydroxydihydromorphinone |
DE1938219A1 (de) * | 1968-07-26 | 1970-02-12 | Sankyo Co | Verfahren zur Herstellung von 14-Hydroxy-normorphinonderivaten |
US4472253A (en) * | 1981-08-17 | 1984-09-18 | The Florida Board Of Regents On Behalf Of The Florida State University | Process for the preparation of an N-substituted 3-O-alkyl-14-hydroxynormorphinone derivative |
-
1984
- 1984-03-27 US US06/593,752 patent/US4639520A/en not_active Expired - Lifetime
-
1985
- 1985-03-26 DE DE8585302102T patent/DE3572172D1/de not_active Expired
- 1985-03-26 IT IT67298/85A patent/IT1184058B/it active
- 1985-03-26 EP EP85302102A patent/EP0159823B1/en not_active Expired
- 1985-03-26 FR FR858504486A patent/FR2566777B1/fr not_active Expired
- 1985-03-26 NO NO851217A patent/NO161975C/no not_active IP Right Cessation
- 1985-03-26 AT AT85302102T patent/ATE45358T1/de not_active IP Right Cessation
- 1985-03-27 ES ES541630A patent/ES8607306A1/es not_active Expired
- 1985-03-27 JP JP60061023A patent/JPH0651702B2/ja not_active Expired - Lifetime
-
1986
- 1986-01-08 ES ES550731A patent/ES8705447A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0159823B1 (en) | 1989-08-09 |
IT8567298A1 (it) | 1986-09-26 |
EP0159823A1 (en) | 1985-10-30 |
FR2566777A1 (fr) | 1986-01-03 |
DE3572172D1 (en) | 1989-09-14 |
ES541630A0 (es) | 1986-05-16 |
NO161975B (no) | 1989-07-10 |
JPH0651702B2 (ja) | 1994-07-06 |
ES8607306A1 (es) | 1986-05-16 |
FR2566777B1 (fr) | 1989-09-29 |
ES8705447A1 (es) | 1987-05-01 |
IT1184058B (it) | 1987-10-22 |
NO851217L (no) | 1985-09-30 |
US4639520A (en) | 1987-01-27 |
NO161975C (no) | 1989-10-18 |
ATE45358T1 (de) | 1989-08-15 |
JPS60218392A (ja) | 1985-11-01 |
ES550731A0 (es) | 1987-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19980327 |